알레르기 환자에서 특이알레르겐 항체 양성율과 관련요인

이선화,남해선,이성수,안현철,황규윤,박준수,,박춘식 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.2

Recently, allergic diseases are very prevalent in Korea, resulting in physical and economic losses during the life. It is well-known that the principle therapy is identification, eradication, and desensitization of allergens. There are many allergic diagnostic tools for identification of specific-allergens. However, none of them is satisfied with its efficiency due to lack of validity. Recently MAST-CLA has been widely used in the allergic clinical fields because of its simplicity and simultaneous identification of allergens. This study was designed to determine the positivity of allergen-specific antibodies using MAST-CLA in patients with allergic diseases, and evaluate the efficacy for allergen detection, compared to results of skin prick test. During June 2000 - September 2001, 325 study subjects visited Soonchunhyang University Chunan Hospital for the evaluation of allergic problems. Among them, 289 subjects were diagnosed with allergic disease and included for the study. Thirty four subjects visited children's allergic unit were evaluated specific allergens using a skin prick test at the same time. Our result as follows; 1. The positive rates of allergen-specific antibodies and total IgE were 51.2% and 73.4%, retrospectively. 2. There was significant difference in positive rate in age group, showing highest in teen ages(73.6%), but insignificant difference in sex in allergen-specific antibodies. 3. The positive rate was 60.4% in allergic rhinitis, 51.3% in allergic dermatitis, 46.9% in bronchial asthma, and 39.1% in urticaria in order(P=0.073). 4. Significant difference in month or season was observed, with highest rate in April(78.1%) and May(72.1%). The highest season was in spring(62.7%), and then summer(52.8%), fall(50.3%), and winter(41.4%) in order (P=0.04). 5. The three highest allergen-specific antibodies were D. pteronyssinus(39.3%), D. farinae(38.3%), and house dust(24.3%) in Korean inhalant pannel, However, in food pannel types of allergen-specific antibody were different as D. farinae(18.5%), Alternaria(18.5%), house dust(17.3%). 6. There were significant agreements between MAST-CLA and Skin prick test (D. farianae Kappa=0.636;D. pteronyssinus Kappa=0.78, both P<0.001) In conclusion, MAST-CLA could detect allergen-specific antibodies in patients with allergic diseases as a simple and valid tool of screening of allergy. Especially, it could be a useful measure of multiple allergens simultaneously in children However, more detailed allergens and valid assay for unmeasured allergens should be identified for Korean-specific allergens.

LiNbO₃ 지연선을 이용한 온도측정시스템에 관한 연구

박남천,박순규 경남대학교 신소재연구소 1994 論文集 Vol.4 No.-

LiNbO₃ 지연선을 이용한 온도측정 시스템을 설계 및 제작하고 그 동작특성들을 평가하였다. LiNbO₃지연선의 지연시간은 온도에 역비례하며 이 지연선을 표면탄성과 발진기의 궤환로에 사용하였다. 이 온도측정 시스템의 분해능은 주파수 계수기의 게이트 시간이 1sec 일 때 400카운트/℃ 정도로 매우 높았고 온도변화에 대한 표면탄성과 발진기의 주파수 이동이 매우 양호한 선형성을 나타내었다. A temperature measurment system using a LiNbO3 delay line was desined fabricated and its operating characteristics were evaluated. The delay time of LiNbO3 delay-line is inversely propotional to the temperature and the delay-line was used as the feedback path of a SAW oscillator. The resolution of the temperature measurment system is very high to the 400 counts/℃ at 1sec gate-time of frequency counter and showed very linear characteristics of the frequency shift of SAW oscillator versus temperature.

정상교합자와 골격성 Ⅲ급 부정교합자의 경추골성숙도에 관한 연구

양규호,최남기,최봉선,이영준,류선열,김선미 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.1

정상교합자와 골격성 Ⅲ급 부정교합자간의 성장 정도에 차이가 있는지를 평가하기 위해 8-12세 여자를 대상으로 하여 진단 석고 모형과 측모두부방사선사진을 기준으로 정상교합자 172명 , 골격성 Ⅲ급 부정교합자 191명 총 363명을 분류하여 연구를 시행하였다. 경추의 하연의 만곡도와 수직·수평 길이의 비를 측정해서 연령이 증가함에 따른 변화를 분석하여 다음과 같은 결론을 얻었다. 1. 연령이 증가함에 따라 제2~6경추의 하연의 만곡도는 정상교합자와 골격성 Ⅲ급 부정교합자 모두에서 일정하게 증가하였다. 2. 연령이 증가함에 따라 제3~6경추의 수직·수평 길이의 비도 정상교합자와 골격성 Ⅲ급 부정교합자 모두에서 일정하게 증가하였다. 3. 제2~6경추의 하연의 만곡도와 제3~6경추의 수직·수평 길이의 비에서 정상교합자와 골격성 Ⅲ급 부정교합자간의 경추골성숙도 차이를 조사한 결과 통계적으로 유의한 차이를 보이지 않았다. 이상의 결과에서 정상교합자와 골격성 Ⅲ급 부정교합자간의 경추골성숙도를 비교했을 때 유의한 차이를 보이지 않았으므로 성장에 차이가 없음을 시사하였다. This study was to evaluate and compare differences of the cervical vertebral skeletal maturity of normal occlusion and skeletal Class Ⅲ malocclusion. Normal occlusion (172 girls) and skeletal Class Ⅲ malocclusion(191 girls) were classified according to diagnosis stone model and lateral cephalogram of Korean girls aging from 8 to 12 years. The concavity of inferior border, vertico-horizontal ratio of cervical vertebrae were observed and measured according to age. Differences of the cervical vertebral skeletal maturity were evaluated. The results were as follows : 1. The concavity of inferior border of the 2nd to 6th vertebrae of normal occlusion and skeletal Class Ⅲ had uniformly increased with age. 2. The vertico-horizontal ratio of the 3rd to 6th vertebrae of girls with normal occlusion and skeletal Class Ⅲ had uniformly increased with age. 3. There was no significant difference in cervical vertebral skeletal maturity between normal occlusion and skeletal Class Ⅲ malocclusion in the concavity of inferior border of the 2nd to 6th vertebrae and in the vertico-horizontal ratio of the 3rd to 6th vertebrae. The results in the study indicate that there is no significant difference of cervical vertebral skeletal maturity between girls with normal occlusion and skeletal Class Ⅲ malocclusion.

산성 불소가 복합레진 표면에 미치는 영향

양규호,육근영,최남기,김선미 대한소아치과학회 2007 大韓小兒齒科學會誌 Vol.34 No.2

복합레진 수복은 치아우식 및 치아우식 예방치료를 위한 대표적인 술식으로 소아치과 영역에서 널리 시행되고 있으며 불소도포는 치아우식 예방을 위한 대표적인 술식으로 1년에 2번 정도 실시되고 있다. 하지만 이러한 이점에도 불구하고 Acidulated phosphate fluoride(APF)가 복합 레진의 표면을 거칠게 한다는 부작용에 대한 논란이 있다. 이에 본 연구에서는 불소도포가 복합레진의 표면에 미치는 영향을 평가하기 위해 시판용 레진인 Solitaire 2^(®)(Heraeus Kulzer, Germany), Metafil CX^(®)(Sun medical, Japan), Composan LCM^(®)(Promedica, Germany), Charmseal^(®)(DenKist, Korea)을 이용하여 시편을 제작하고, 불소젤은 Topex^(®)(Sultan Dental Products, Canada)를 각각 1분과 4분동안 도포시킨 후 변화를 관찰하여 다음과 같은 결과를 얻었다. 1. 불소젤을 도포시키지 않은 대조군에서 가장 평활한 표면을 보였으며 1분군, 4분군 순으로 표면 거칠기가 증가하였다. 그리고 Composan LCM^(®)을 제외한 모든 제품에서 유의한 차이를 보였다(p<0.05). 2. 국소도포용 불소젤을 도포한 각 레진 시편의 무게 차이를 비교한 결과 대조군, 1분군, 4분군 간에 유의한 차이는 없었다(p>0.05). 3. 주사전자현미경 관찰시 불소젤을 도포시킨 실험군은 대조군에 비해 거친 표면을 나타내었다. Composite resin restorations are widely used to restore decayed teeth or preventive restoration in children. Children often receive topical fluoride treatments on a semiannual basis. However there is concern that topical acidulated phosphate fluorides (APF) may cause deterioration of composite resins. The aim of this study was to evaluate the surface changes in composite resins due to topical fluoride application. Composite resins(Solitaire 2^(®), Metafil CX^(®), Composan LCM^(®), Charmseal^(®)) in topical fluoride agents were immersed and their surface roughness, weight loss and SEM findings were evaluated. The results were as follows: 1. The 4 minutes-immersion group showed more roughened surface than 1 minute-immersion group and the control group showed the smoothest surface among all the materials, and there was statistically significant difference between the groups except the Composan LCM^(®)(P<0.05). 2. There was no significant difference between the 1 minute-immersion group and 4 minutes-immersion group in weight loss (P>0.05). 3. The experimental group treated with topical fluoride gel showed generally more roughened surface than control group in the SEM findings.

웨이브릿 변환 영역 적응필터에 의한 유한 임펄스 응답 필터시스템 확인

박순규,박남천,이수흠 慶南大學校 附設 工業技術硏究所 1998 硏究論文集 Vol.15 No.2

기존의 시간영역직 접형 유한 임펄스 응답 적응필터는 그 구조가 매우 간단하기 때문에 여러 분야에 응용되고 있으나, 이 적응필터는 일반적으로 수렴률이 매우 늦다. 변환영역 적응필터는 적응 알고리듬의 수렴속도 증가를 위해 유익하게 사용된다. 웨이브릿 변환은 프로세스가 비정적인 경우에도 Karhunen-Loeve변환과 매우 유사하다. 그러므로 웨이브릿 변환된 출력의 자동상관 마트릭스는 거의 대각이며, 변환 영역에서 간단한 전처리를 하면 수렴률을 매우 향상시킬 수 있다. 또한 변환에 Harr 웨이브릿을 이용하면 곱셈없이 변환이 가능하다. 이 논문에서는 웨이브릿 변환 영역 적응필터를 구성하고, 이를 유한 임펄스 시스템 확인에 적용하였다. 컴퓨터 시뮬레이션 결과를 DET 영역 적응 유한 임펄스응답 적응필터에 의한 결과와 함께 나타내었다. The conventional time domain direct-form FIR filter has been used for a variety of application, since it presents a very simple implemention, however, in general, the convergence rate of this adaptive filter is very slow. The transform domain adaptive filter can be used advantageously to increase the speed of convergence of the adaptive algorithm. The wavelet transform behaves as a good approximation to Karhunen-Loeve(KL) transform even when the underlying process is nonstationary. Therefore, the autocorrelation matrix of the wavelet transformed output is nearly diagonal. By using a simple preconditioning in the transformed domain, the conditioning can be improved resulting in dramatic increase in the convergence rates. And by using the Harr wavelet, we can transform without multiplication arithmetic. In this paper, a wavelet transform domain adaptive filter has been constructed and applied to the FIR filter system identification. Computer simulation results are shown with the results obtained by the DFT domain adaptive FIR filter.

전립선 비대 증상 자각군과 일반 남성군의 전립선 비대 증상, 일상생활 활동, 성생활 만족 및 안녕감 비교

이규은,오점숙,김현주,김남선 성인간호학회 2003 성인간호학회지 Vol.15 No.3

Purpose: This study was designed to explore and compare the prostatic hypertrophoc symptoms, activities of daily living, satisfaction of sexual activities and well-being among subjects with prostatic hypertrophic symptoms and the general population. Method: One hundred subjects with prostatic hypertrophic symptoms and one hundred general persons were recruited in K medical center. The data were collected from October 20, 2001 to March 30, 2002 by structured questionnaire. Result: The results were the following; 1. The percentage of mild(0~7), moderate(8~19) and severe(20~35) symptoms between subjects with prostatic hypertrophic symptoms and general persons were 6% : 60%, 54% : 39%, 40% : 1%. 2. There was a significant difference in prostatic hypertrophic symptoms(t=12.82, p<.001), in activities of daily living(t=-7.77, p<.0001), in satisfaction of sexual activities (t=-4.80, p<.0001), in well-being(t=-4.80, p<.0001) between subjects with prostatic hypertrophic symptoms and general persons 3. There was a significant difference in activities of daily living(F=16.28, p<.0001), satisfaction of sexual activities(F=3.98, p<.05) according to prostatic hypertrophic symptoms in subjects with prostatic hypertrophic symptoms. Conclusion : According to the above findings, prostatic hypertrophic symptoms influence activities of daily living, satisfaction of sexual activities, well-being of subjects with prostatic hypertrophic symptoms negatively.

男左·女右 理論에 따른 顔面神經痲痺의 臨床的 考察

李寬順,金南權,林圭庠 圓光大學校 韓醫學硏究所 1997 원광한의학 Vol.7 No.1

著者는 臨床에서 흔히 患者들로부터 구안와사의 豫候에 대해 "男左女右"와 關聯하여 질문을 받으므로 이에 대한 臨床的 妥當性을 알아보기 위해 1995年 9月 1日부터 1996年 8月 31日 까지 1年間 圓光大學校 附屬 全州韓方病院 外官科 外來에 來院하여 구안와사를 診斷받은 總 148명을 對象으로 發病動機 및 身體狀態, 年齡別 分布, 男女 左右別 發生率, 總 來院患者에 대한 治療率, 年齡別 發生率, 男女 左右에 따른 治療率을 각각 臨床 觀察하여 다음과 같은 결과를 얻었다. 1. 發病動機 및 身體狀態는 風寒과 연관되는 原因이 가장 많았으며, 肉體過勞, 精神過勞, 飮酒 등의 순으로 나타났고, 2가지 이상의 原因이 있는 경우는 精神過勞와 肉體過勞가 겸해오는 경우가 많았다. 2. 年齡別 分布는 50-59세가 가장 높았고, 40-49세, 30-39세, 20-29세, 60-69세, 70세 이상, 1-9세, 1세 이하의 순으로 각각 나타났다. 3. 男女 左右別 發病率은 右側 顔面神經이 痲痺된 男子 患者가 가장 많았으며, 右側 顔面神經이 痲痺된 女子 患者, 左側 顔面神經이 痲痺된 男子 患者, 左側 顔面神經이 痲痺된 女子 患者 순으로 나타났으나 發病率에 큰 차이는 없었다. 4. 總 來院患者 148명에 對한 治療率은 52.53%로 나타났다. 5. 年齡別 治療率은 1-9세가 가장 높았으며, 70세 이상, 50-59세, 40-49세, 60-69세, 20-29세, 30-39세, 10-19세의 순이었고, 주로 中·老年層이 治療率이 높게 나타났다. 6. 男女와 左右에 따른 治療率은 顔面神經痲痺의 女子 患者가 가장 높게 나타났고, 右側 顔面神經痲痺의 男子 患者, 左側 顔面神經痲痺의 女子 患者, 左側 顔面神經痲痺의 男子 患者의 순으로 나타났고, 男女 모두 右側에 發病한 患者의 治療率이 左側보다 높게 나타났으나, 특별한 有意性은 없었다. 以上의 結果로 보아 韓醫學的 生理 病理理論인 男左女右의 豫候와 治療率은 一致하지 않았으나 此後 좀더 많은 患者數와 오랜 期間의 臨床을 통한 硏究가 要求될 것으로 思料된다. The author analyzed 148cases of Facial Palsy, who were treated in the Jeon-ju Oriental Medical Hospital of Wonkwang University from September 1995 to August 1996. I've examined the 148 cases in the view of the etiologic distributions, the age, the relationship of the sex and paralytic side, and the ratio of recovery according to the age, the relations of sex and paralytic side. The following results are obtained. 1. The ratio of punghan(風寒) was 18.24%(27 cases), overwork was 14.86%(22 cases), stress was 12.84%(19 cases), excessive drinking was 2.70%(4 cases), teeth pain was 2.02%(3 cases), and idiopathy was 37.84(56) and etc. 2. The ratio of 5th decade were 20.95%(31 cases), 4th decade was 18.25%(27 cases), 3th decade was 17.57%(26 cases), 2th decade was 14.19%(21 cases), 6th decade was 12.16%(18 cases), over seventy was 10.81%(16 cases), teenagers was 4.05%(6 cases), under teenagers was 1.35%(2 cases), and infant was 0.67%(1 case). 3. The ratio of the male-right was 28.38%(42 cases), female-right was 25.68%(38 cases), male-left was 22.30%(33 cases), female-left was 21.62%(32 cases), female-both side was 1.35%(2 cases) and male-both side was 0.67%(1 case) in order. 4. When we examined the degree of recovery about the 148 patients, perfect cure was seen in 17.57%( 26 cases), excellent in 25.00%(37 cases), good in 22.30%(33 cases), fair in 20.27%(30 cases), poor in 14.86%(22 cases). The total remedial value of the 148 patients was revealed 52.53%. 5. When we examined the 148 patients the remedial value of the infant was 50.00%, under teenagers 62.50%, teenagers 41.67%, 2th decade 47.62%, 3th decade 44.23%, 4th decade 54.63%, 5th decade 58.87%, 6th decade 51.39%, over seventieth 60.94%. The remedial value of under teenagers, 4th decade, 5th decade, over seventieth were higher than the total remedial value(52.53%) 6. In the point of the relationship of the sex and the paralytic side, the remedial value of male-left was 51.47%, male-right 53.45%, male-both side 50.00%, femaled-left 47.62%, female-right 58.75% and female-both 37.50%. The remedial value of male-right(53.45%) and female-fight(58.75%) were higher than the total remedial value(52.53%). These results demonstrated that in the point of prognostic view, there was little concerned with the traditional rule of sex-paralytic relationship that man is awed left paralysis and woman right paralysis.

웨이브릿 변환 영역의 일반화된 서브밴드 분해 FIR 적응필터를 이용한 채널 등화기

박남천,박순규 慶南大學校 附設 工業技術硏究所 1997 硏究論文集 Vol.15 No.1

웨이브릿 변환 영역의 일반화된 서브밴드 분해 FIR(finite impulse response) 적응 필터를 이용한 새로운 채널 등화기를 구성하였다. 이 적응 필터의 희소 인자는 균일하지 않고 변환 레벨이 1 증가할 때 2 감소 한다. 구성된 적응필터를 이용한 채널 등화기의 수렴 속도를 조사하고 DFT(discrete fourier transform) 변환 영역의 일반화된 FIR 필터를 이용한 채널 등화기의 수렴 속도가 비교 평가하였다. A new channel equalizer using the adaptive filter based on the generalized subband decomposition FIR(finite impulse response) filter in the wavelet transform domain is designed. The sparsity factor of the subfilter used in this adaptive filter is not uniform but decreases by two as the wavelet transform level is increased by one. The convergence speed of the channel equalizer using the designed adaptive filter is tested and compared with the channel equalizer using adaptive filter with the DFT(discrete fourier transform) domain generalized subband FIR filter.

호흡기 감염증에 대한 Roxithromycin(Rulid^(�))의 임상 효과

노흥규,김남재,서지원,김주옥,김선영 최신의학사 1990 最新醫學 Vol.33 No.11

웹 카메라를 이용한 시설 내 국화생산 광 환경 원격 모니터링

정선옥(Sun-Ok Chung),김용주(Yong-Joo Kim),이규호(Kyu-Ho Lee),성남석(Nam-Seok Sung),이철휘(Cheol-Hwi Lee),노현권(Hyun-Kwon Noh) 충남대학교 농업과학연구소 2015 농업과학연구 Vol.42 No.4

Increase of national family income improved demand of high-quality and year-round horticultural products including chrysanthemum. To meet these demand, farmers have introduced protected facilities, such as greenhouses, of which environmental conditions could be monitored and controlled. Environment management up to three weeks after transplanting is critical for chrysanthemum quality. Artificial lighting and light-blocking screen are especially important for long-day (day period > 13 hours) and short-day (night period > 13 hours) treatments. In this study, a web-camera was installed, and the image was obtained and transmitted to mobile phones to monitor the status of 3-wavelength(RGB) lighting environments. RGB pixel values were used to determine malfunctioning of the lighting lamps, and leaking out and incoming illumination status during short-day and long-day treatment periods. Normal lighting lamps provided RGB pixel values of 240~255. During long-day treatment period, G pixel values were useful to detect abnormal lighting conditions (e.g., leaking). During short-day treatment period, R pixel values were useful to determine incoming light (e.g., sun-light). Results of this study would provide useful information for remote monitoring of light conditions for protected chrysanthemum production under artificial lights.