사염화탄소의 간독성에 대한 파두 다당류분획의 예방효과

이은경,길이룡,소동수,창동신,전선덕,정명규,문창규 한국환경독성학회 1996 환경독성보건학회지 Vol.11 No.2

In present study, we fractionated polysaccharides from Croton tiglium and investigated their hepatoprotective effects on CCI₄ intoxication. Polysaccharide fraction of which molecular weight is over 300,000(HP) showed the most potent hepatoprotective effects on CC1₄ intoxication. Lipid peroxidation, BAST and sALT were used as parameters to evaluate the liver damage. Glucose, xylose and arabinose were found to be monosaccharides composing sugar moiety of HP.

우리나라 원자력산업의 기술이전 특성에 관한 연구

이영덕,김명환 충남대학교 경상대학부설 경영경제연구소 1999 경영논집 Vol.15 No.1

원자력 산업분야에서 우리 나라가 기술자체의 속성상 기술후발국의 한계를 극복하기 어려웠음에도 불구하고 비교적 빠른 기간 내에 기술개발에 성공할 수 있었던 것은 자체 기술개발의 노력뿐만 아니라 무엇보다도 선진국으로부터 이전된 기술의 개량화를 통한 기술의 고도화를 달성하였다는 사실을 간과할 수가 없다고 하겠다. 따라서 본고에서는 상용기술이 본격적으로 도입된 지난 10여 년간 원자력기술개발 및 실용화과정에서 추진해 온 기술이전의 유형을 파악하고, 나아가 원자력산업의 기술이전 유형과 영향요인에 관한 선험적 관계를 빈도분석을 통하여 탐색적으로 고찰해보는 연구를 수행하였다.

젖소 足皮膚炎에 대한 오존연고의 治療 效果

이수진,전무형,조성환,김덕환,박창식,김명철 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

Thirty dairy cows with pododermatitis were selected and treatment effect of ozone ointment for bovine pododermatitis was investigated. In addition, bactericidal effect of ozone ointment on etiological agent of bovine pododermatitis was evaluated. The pathohistological examination for the pododermatitis, according to application with ozone ointment was investigated. Thirty dairy cows were divided two groups: control group(vaseline group: 15 cows), treatment group(ozone ointment group: 15 cows). Various parameters were evaluated in terms of the lameness score, swelling score, lesion score, WBC, neutrophil, pathohistological finding, and antimicrobial action. As compared with vaseline group, ozone ointment group revealed significant decrease of lameness (p<O.05), swelling (p<O.O1) and lesion score (p<O.05) were shown in hoof lesions on 14 days after application. In hematological findings, WBC count revealed slightly high values within normal range before treatment, however, this was I Corresponding author improved on 14 days after application of ozone ointment. The number of neutrophils was slightly higher than that of normal, however. this was improved on 14 days after application of ozone ointment. In pathohistological findings, normal dermal tissue was found in tissues with pododermatitis on 14 days after application of ozone ointment. In antimicobial action, marked decrease rate of bacteria was observed in feet of all cases treated with ozone ointment. The decreasing rate of bacteria in anaerobic culture was higher than that in aerobic culture.

젖소 足皮膚炎에 대한 오존수의 治療 效果

이수진,조성환,전무형,김덕환,박창식,한홍율,김명철 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

This study was carried out to determine therapeutic the effect of ozonated water therapy on bovine pododermatitis. In addition, bactericidal effect of ozonated water on etiological agent of bovine pododermatitis was examined. The pathohistological examination for the pododermatitis, according to application with ozonated water and ozone ointment was investigated. Thirty healthy cattle were divided two groups(each of 15) : control group (povidone group), treatment group (ozone solution group). Various parameters were evaluated in terms of the lameness score, swelling score, lesion score, WBC count, neutrophil count, pathohistological finding, and antimicrobial action. The decrease of lameness and lesion score were shown in hoof lesions on 14 days after application of ozonated water. Significant decrease of swelling was shown in hoof lesions on 14 days 1 Corresponding author after application of ozonated water(p < 0.01). In hematological findings, WBC count revealed values within normal range. The number of neutrophils was slightly higher than that of normal, however, this was improved on 14 days after application of ozonated water. In pathohistological findings, recovery was rapid macroscopically and microscopically in the treatment with ozonated water on the hoof lesions and ozonated water was effective. In antimicobial action, bactericidal effect was observed in treatment with ozonated water on the hoof lesions and ozonated water was effective.

정전 열 접합을 이용한 Multi-Substrate Bonding

이덕중,주병권,최우범,한정인,조경익,이광배,장진,오명환 경북대학교 센서기술연구소 1997 센서技術學術大會論文集 Vol.8 No.1

We performed silicon-to-glass bonding using silicon direct bonding followed by anodic bonding(SDAB). Initial bonding between glass and silicon was caused by the hydrophilic surfaces of silicon and glass ensemble using silicon direct bonding(SDB) method. We found that the bonded specimen using SDAB process had higher strength than one using anodic bonding process only. We performed multiple layer bonding by SDAB, which is glass- silicon -glass as sandwich structure. In the silicon wafer, the (1mm x 2mm x 500μm)-sized cavity was formed by the anisotropic etching of the silicon substrate in EPW(Ethylendiamin-Pyrocatechol-Water). And, the cavity was sealed with glass wafers by SDAB method.

동물원에서 사육중인 Japanese Macaque (Macaca fuscata)에서 Zoletil 마취에 관한 연구

이재일,이수진,홍성혁,신남식,김덕환,박창식,전무형,조종민,김영석,김명철 충남대학교 형질전환복제돼지연구센터 2004 논문집 Vol. No.8

To evaluate the effects of Zoletil (tiletamine-zolazepam) that have been widely used for the chemical restraint and anesthesia of primates, on physiologic alteration, blood gas analysis and anesthetic duration in the Japanese macaque(Macaca fuscata), this study was carried out. Zoleril was administered by intramuscular injection, Evaluation of temperature, heart rate, respiration rate and blood gas analysis were performed before administration ancl at 1,10, 20, 30, 40, 50 and 60 min after administration, and induction and maintenance time was recorded. There was no significant difference in heart rate, PCO₂PO₂after Zolcril administration and temperature, respration rate, pH were significant difference compared with those of before administration, The induction time was 2.5±l.Omin and maintenance time was 86±23.2min. It was considered that Zoletil could he usefully used for the sedation and immobilization of Japanese macaque reared in zoological garden.

구강내에서 재광화용액 "R"의 법랑질 초기 우식병소에 대한 재광화의 정량적 평가

김명은,정일영,금기연,이찬영,노병덕 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.2

Dental caries is a chronic disease that causes the destruction of tooth structure by the interaction of plaque bacteria, food debris, and saliva. There has been attempts to induce remineralization by supersaturating the intra-oral environment around the surface enamel, where there is incipient caries. In this study, supersaturated remineralized solution "R" was applied to specimens with incipient enamel caries, and the quantitative ananlysis of remineralization was evaluated using microradiography. Thirty subjects volunteered to participate in this study. Removable appliances were constructed for the subjects. and the enamel specimen with incipient caries were embedded in the appliances. The subjects wore the intra-oral appliance for 15 days except while eating and sleeping. The removable appliance were soaked in supersaturated solution "R", saline, or Senstime® to expose the specimen to those solutions three times a day, 5 minutes each time. After 15 days, microradiography was retaken to compare and evaluate remineralization. The results were as the following: 1. The ratio of remineralized area to demineralized area was significantly higher in the supersaturated solution "R" and Senstime® than in the saline (p<0.05) 2. Remineralization in the supersaturated buffer solution "R" occurred in the significantly deeper parts of the tooth, compared to the Senstime® group containing high concentration of fluoride.(p<0.05) As in the above results, the remineralization effect of remineralized buffer solution "R" on incipient enamel caries has been proven. For clinical utilization, further studies on soft tissue reaction and the effect on dentin and cementum are necessary. In conclusion compared to commercially available fluoride solution, remineralization solution "R" showed better remineralization effect on early enamel caries lesion. so it is considered as effecient solution for clinical application

개의 심장사상충증 발생례

김명철,이수진,이재일,박창식,전무형,김덕환,임승평 충남대학교 형질전환복제돼지연구센터 2004 논문집 Vol. No.8

A 5 year old, 13kg, Jindo dogs was presented with clinical signs of anorexia, weakness and exercise intolerance, and diagnosed as dirofilariasis by hematology, blood chemistry and ultrasonography. In hematology and blood chemistry, the presence of microfilariae in the blood. anemia, leukocytosis, hemoglobinuria and jaundice were revealed. In ultrasonography, heartworms were found in the right ventricle artery and pulmonary artery as structures of hyperechoic dots or streaks. Because of the dog's poor physical status, the owner requested euthanasia. In autopsy, fifty odd of heartworms were ascertained in the right ventricle and pulmonary artery. Tricuspid valve in the orifice of right ventricle and right atrium, and chordae tendineae were deliquesced.

일부 농촌부인의 자궁경부암 집단검진시 수진과 관련된 결정요인의 분석연구

金順德,廉容泰,李明淑 고려대학교 의과대학 1988 고려대 의대 잡지 Vol.25 No.3

Among the females in Korea, cervical cancer is the most common malignant tumor. Exfoliative cytology is a highly sensitive and inexpensive screening technique for cervical cancer and its precursors. The detection and eradication of the precursors have led to a significant fall in cervical cancer incidence and mortality rates in those areas of some developed countries in which there has been widespread and prolonged use. Interviews were carried out during the period from December,1986 to March, 1987 to study the determinants of the positive health seeking behavior of married women living in Jeomdong Myon, Yeoju Kun, Kyonggi Province focusing on the cervical cancer screening. Interviewed were 291 married women who participated in the cervical cancer screening and 249 who didn't. The path analysis and the discriminant analysis were used to identify major determinants for the health behavior concerned with cervical cancer screening. The results of this study were summarized as follows: 1. Belief, motive and action levels to the cervical cancer screening were 87.5%, 70.2% and 53.9% each. Belief and motive levels were 95.5%, 62.8% in the participants of the screening, and 78.2%, 33.3% in nonparticipants. 2 Determinants for the belief were age, regular health check up, benefit, susceptibility, level of knowledge, marital status, and interpersonal interaction. These determinants were able to explain 28.5% of the belief. 3. Determinants for the motive were belief, symptom, acquaintance who participated in cervical cancer screening, benefit, age, regular health check up, interpersonal interaction, acquaintance of cancer cases other than cervical cancer, and level of knowledge. These determinants were able to explain 26.9% of the motive. 4. Determinants for the action were occupation, age, symptom, belief, marital status, acquaintance who participated in cervical cancer screening, motive, some basic medical equipment kept in home, interpersonal interaction, acquaintance with cervical cancer patient, and mass media communications. These determinants were able to explain 37.8% of the actions. The variables having indirect effects on the actions through the belief and motive were susceptibility, benefit, level of knowledge, acquaintance with cancer cases other than cervical cancer, and regular health check up. 5. The belief was able to explain 18.2% of the motive, belief and the motive was able to explain 9.8%of the action. 6. The hit ratio was 78.82% for the prediction of the action in the discriminant analysis with the discriminating variables.

대동물 임상에서의 침술마취의 적용

김명철,김덕환,전무형,홍성혁,박창식,이재일,이수진,김영석 충남대학교 수의과대학 동물의과학연구소 2002 動物醫科學硏究誌 Vol.10 No.-

Acupuncture is used to treat pathological conditions and to prevent pain from arising. The pathological conditions that can be treated can be painless or painful conditions. Acupuncture analgesia (AA) is a specific form of acupuncture: the stimulation of the acupuncture points must be strong and long (about 15 to 30 minutes) before a local or general analgesia or hypalgesia will develop. Development of modern AA began in the late fifties. Effectiveness of acupuncture in alleviation of pain was quickly noticed and brought to the medical researchers and surgeons. Through their diligent pursuit, AA has been established as a viable alternative for relief of pain and substitution of conventional anesthesia. In veterinary medicine, early successful applications of AA to surgery of domestic animals were reported in the late sixties. Local or regional anesthesia is often preferred to general anesthesia in cattle. Acupuncture was effective in inducing analgesia. Regional electroacupuncture analgesia is potentially useful for standing surgeries in cattle. Some standing surgeries may be easily accomplished using electroacupuncture anesthesia.