자전 고온 합성 반응법을 이용한 B₄C의 제조에 관한 연구

金錫胤,金明秀,金岩洙 弘益大學校 科學技術硏究所 1998 科學技術硏究論文集 Vol.9 No.2

유산양 유방염에 대한 Chitosan 약침의 치료 효과

황수현,서진석,김덕환,김명철,신상태,전무형,南三郞,김영찬,이우근,표수일 충남대학교 수의과대학 동물의과학연구소 1999 動物醫科學硏究誌 Vol.7 No.-

To improve the therapeutic method for mastitis, treatment effect of chitosan pharmacopuncture was examined in three milking goats(A,B and C). Mastitis was artificially induced in two milking goats(A and B) and one goat(C) was naturally infected case with mastitis. The acupoint used was Yang-Ming and chitosan suspensions(provided from Tottory University, Japan: 30㎎ of chitosan/㎖)were injected to the acupoint with 5㎖/time for 3 days, respectively. As for the change of somatic cells in milk along with chitosan pharmacopuncture, they showed a decreasing tendency after increase on the 3rd day in all udders of B. In addition, as for the change of total leukocyte counts of peripheral blood with chitosan pharmacopuncture, they showed a decreasing tendency after increase on the 3rd day in B and C except A which showed a increasing tendency until on the 7th day. In the change of neutrophil/lymphocyte(N/L) ratio, increasing tendency was seen in A and C but increasing tendency after slight decrease was observed in B. Further, in the change of serum total protein and A/G ratio, serum total protein content was decreased after slightly increase on the 3rd day in A, and they were decreased after increase until on the 7th day in B and C, respectively. As for the change of A/G ratio, different pattern increasing tendency was shown in A, B and C.

경연 대회를 통한 초ㆍ중고생의 창의력 신장 효과에 관한 연구

이희복,육근철,류해일,김현섭,김희수,박달원,유병환,김선효,김여상,서광수,변두원,서명석,배성효,박종석,심규철,이성희 공주대학교 과학교육연구소 2001 과학교육연구 Vol.32 No.1

미래 사회를 대비하기 위한 개인의 개성을 존중과 창의적인 능력을 지닌 인간을 양성을 목적으로 충청남도 지역의 초 ㆍ 중고등학생들을 대상으로 한 창의력 경연대회가 공주대학교 과학교육연구소에서 개최되었다. 충청남도 초 ㆍ중 ㆍ 고등학생들을 대상으로 실시한 창의력 경연대회는 창조적 아이디어를 내어 스스로 문제를 해결해 나갈 수 있는 교육 프로그램을 제공하는 좋은 기회였음이 확인되었으나, 일부의 팀에서만 참신하고 재미있는 아이디어들이 제안되었다. 여학생의 참가자 수가 상당히 증가하였으며, 대체적으로 입상권의 학생들의 상당 부분이 여학생이라는 것이 특이할만하다. 학년이 올라감에 따라서 창의적인 아이디어를 내는 양이나 질에 있어서 뒤떨어지는 것으로 분석되었으며, 토론 학습의 적응력이 미흡하고 발표력 및 청취력에 있어서도 떨어지는 것으로 나타났다. 따라서 중 ㆍ고등학교의 학교교육에서도 학생들에게 프로젝트형 탐구학습 프로그램의 적용은 물론 토론식 수습을 통한 학생들의 사고의 전환의 기회를 제공해야 할 것으로 사료된다. The creativity competition was held to foster the creativity of elementary and secondary school students in the Institute of Science Education, Kongju national University. It was found that the creativity competition effected on the improvement of inventing creative ideas and problem solving activities. But, only some competitors participated in semifinal and final contests, presented original and interesting ideas. More female students participated in competition than last year. More female participants were awarded a prize than males. Totally, participants were defective in discussion and communication, and presentation and listening ideas. Increasing grades correlated inversely with creativity and originality. There is need of inquiry project teaming programs and presenting opportunities of conversion of thinking by discussing instructions in school

국가의 자율성과 개입력 : 한국의 중화학공업화 계획을 중심으로

김명수 한양대학교 사회과학대학 1988 社會科學論叢 Vol.7 No.-

Contrary to the conventional image of an "ever-strong" Korean state in the literature, the strength of the Korean state which we could observe in the process of the state-initiated Heavy and Chemical Industrialization (HCI) was far from being strong. Although the state achieved same of its autonomously driven objectives, the shape of the project was not the one which the state intended to have. The particular shape and content of the HCI project compell us to rethink the conventional theories of the "dependent" capitalist state. At the outset of the HCI project, the Korean state had relatively high degrees of state autonomy and intervening capacity at its disposal. The state could initiate the HCI project in accordance with its own purview, most importantly, the development of self-defense industry, the deepening-of industrial structure, and the renewal of decaying political legitimacy of the President Park. The state could wield its discretionary poller over the big business groups, Jaebols, by setting terms of their entry in the HCI project. However, the Korean state put itself into a precarious position vis-a-vis Jaebols by deeply committing itself to the HCI project. The Jaebols aggressive thrust for hegemonic position in the Korean economy paralyed the strategic decision-making apparatus of the state. Incongruence among the strategic units within the state resulted in a series of incongruent state actions and a massive scales of duplicated overinvestment in the HCI sector. The state intervention in realigning the disarray was abortive primarily because the Jaebols refused to follow the state's direction and because a unit of the state apparatus 'revolted' against the state's own action. By then, the autonomy and intervening capacity' of the Korean state vis-a-vis'is the Jaebols had substantially been eroded. It is clear that the terms of alliance between the Korean state and Jaebols underwent a substantial transformation during the course of the HCI project. The case succinctly illustrates that strong state intervention with highly autonomous objectives could undercut the state strength. The above point substantially negates the utility of the static and overall typology of the state strength, either "strong state" or "weak state." It also illustrates the inadequacy of "society-centered" theories of the state, either neo-Marxist theories of "the" class-bounded capitalist state or pluralist theories of the "neutral" state. Since both perspectives deny the possibility that the state could generate and pursue autonomous objectives, both are inadequate in explaining the Korean state's action in the HCI project. Instead, it strongly suggests that it is necessary to conceive the state in its own terms.

유아의 구강관리에 관한 보호자의 인지도 조사

김명진,선예경,심연수 대한소아치과학회 2000 大韓小兒齒科學會誌 Vol.27 No.2

전반적인 유아의 구강관리에 관한 보호자의 인지도를 알아 보고, 이를 통한 구강관리에 대한 동기유발을 목적으로 1998년 7월부터 1998년 8월까지 삼성서울병원 소아과에 내원한 아동과 강남구 일원동 일대 유치원 및 어린이집 8곳의 만 3세 이하 아동 350명의 보호자를 대상으로 시행한 설문 조사를 통해 다음과 같은 결과를 얻었다. 1.남성보다는 여성이, 그리고 교육정도가 높을수록 치과 지식정도가 높았으며, 연령이나 경제 수준과는 무관하게 나타났다. 2.치아의 생성시기에 대해 응답자의 59%가 태아기라고 답하였다. 3.구강관리 시작시기는 응답자의 76%가 맹출 전이라고 하였으며, 63%가 실제로 만 1세 미만에 구강관리를 시작한다고 하였다. 4.구강관리 방법에 대해 응답자의 70%가 거즈를 사용한다고 하였다. 5.응답자의 57%가 만 1세 이후에도 계속 수유한다고 하였다. 6.우유병 우식증에 대한 인지도는 45%로 나타났다. 7.유치수복의 필요성에 대하여서는 90%가 필요하다고 하였으며, 31%에서 최초의 치과 내원시기를 만 2세 경이라고 하였다. 8.47%의 보호자가 치아우식이 감염성 질환임을 인식하지 못하였다. 9.응답자의 33%만이 임신 중 치과 검진을 받았다고 하였고, 소아과나 산부인과에서 구강관리에 관한 지도를 받은 것은 11% 뿐이었다. 10.주로 육아 서적에서 유아의 구강관리에 관한 정보를 얻는 것으로 나타났다. 11.보호자들의 전반적인 치과지식과 실천정도는 유아들에게 적절한 구강관리를 제공하기에 충분치 않은 것으로 나타났다. 주요어 : 유아, 구강건강관리, 부모, 교육

오픈마켓에서의 고객 만족과 충성도의 관계에 관한 연구

김명수 釜山 大學校 經營 經濟 硏究所 2009 經營 經濟 硏究 Vol.28 No.1

Mycophenolic Acid와 Rapamycin이 흰쥐 사구체 혈관간세포증식과 세포외기질 생성에 미치는 영향

김명수,박제현,하헌주,허규하,서지연,김유선,김혜진,박기일 이화여자대학교 약학연구소 2004 藥學硏究論文集 Vol.- No.14

Background: Excess proliferation and extracellular matrix (ECM) accumulation of mesenchymal cells such as vascular smooth muscle cells (VSMC) and glomerular mesangial cells cause chronic allograft nephropathy showing transplant vascular sclerosis and glomerulosclerosis. Mycophenolic acid (MPA) and rapamycin (RPM) are well known as strong inhibitors of VSMC proliferation, but their effects on the glomerular mesangial cells are not yet clearly understood. This study examined the effects of MPA or RPM on PDGF-induced proliferation and ECM accumulation in rat glomerular mesangial cells. Methods: Mesangial cells isolated from the glomeruli of Sprague-Dawley rats were cultured with DMEM containing 20% fetal bovine serum. Growth arrested and synchronized cells were administered with test drugs (MPA10 nM-10μM, RPM 0.1 nM-1μM) before the addition of PDGF 10 ng/mL. Cell proliferation was assessed by [³H]thymidine incorporation, collagen by [³H]proline incorporation, and fibronectin, ERK, and p38 MAPK by Western blot analysis. Results: PDGF increased mesangial cell proliferation by 4.64-fold. Compared to stimulated control, MPA above 500 nM and RPM above 10nM showed a significant inhibitory effect in a dose-dependent manner. The IC_(50) of MPA and RPM against PDGF-induced mesangial cell proliferation were around 500 nM and 100 nM, respectively. The collagen synthesis was also inhibited by MPA and RPM, but the fibronectin secretion was inhibited by MPA alone. The proliferation of mesangial cell correlated with activation of ERK and. p38 MAPK. MPA, but not RPM, inhibited ERK and p38 MAPK activation. Conclusion: This study demonstrated that MPA and RPM significantly inhibited PDGF-induced proliferation and ECM production in rat glomerular mesangial cells. The inhibitory effects of MPA, but not RPM, are correlated with ERK and p38 MAPK.

성인에서 발병한 지역사회폐렴의 원인으로서 호흡기 바이러스의 역할

김지희,곽영호,나병국,이주연,신구철,정혜선,홍정연,오명돈,정희진,김민자,배현주,김양리,신완식,강재명,우준희,어수택,이환종 대한감염학회 2001 감염 Vol.33 No.1

Purposes : To investigate the viral etiology of community-acquired pneumonia in Korean adults, we have detected respiratory viruses (Respiatory syncytial virus, adenovirus, influenza virus and parainfluenza virus) in the way of prospective, multi-center study. Methods : From July 1997 to April 2000, nasal aspirates or sputum were obtained from adults patients with community pneumonia admitted to the participating hospitals and transferred immediately to the central laboratory at the Seoul National University Children's Hospital. The specimens were divided into three parts. One part was used for indirect immunofluorescent test for respiratory viruses, the other part for the culture of RSV and adenovirus in HEp-2 cell monolayer. The other part was used for the culture of influenza virus and parainfluenza virus in MDCK or LLC-MK2 cell monolayers. Results : Of 317 samples, 32 (10.1%) specimens were positive for viral agent by indirect IF staining or culture, including one dual-infected specimen (adenovirus and parainfluenza virus). Influenza virus was most commonly detected (16 specimens). Parainfluenza virus, adenovirus and RSV were detected in 10, 4 and 3 patients, respectively. All isolated influenza viruses were type A (H3N2 in 9 patients, HIN1 in 2 and unspecified in 5), and 8 out of 10 parainfluenza virus isolates were type 3. Conclusion : Similar to previous reports from other countries, a significant portion of community-acquired pneumonia in Korean adult is caused by respiratory viruses. (Korean J Infect Dis 33:8~14, 2001)

오디첨가 요구르트의 발효특성

김혜경,배형철,남명수 충남대학교 농업과학연구소 2003 농업과학연구 Vol.30 No.1

오디의 건강 효과와 유산균 배양시 발효촉진 효과를 기대한 새로운 요구르트 개발의 일환으로, 환원 탈지유에 건조방법에 따른 오디의 첨가와 오디 첨가수준을 달리 한 요구르트 제조시 pH, 산도, 유산균수의 변화, 오디요구르트의 저장성 및 관능검사를 수행한 결과는 다음과 같다. 1. 생오디, 동결건조오디, 열풍건조오디는 보통 요구르트에 비하여 pH 저하와 산 생성의 증가가 빨라 발효촉진 효과를 보였으며, 처리구 간에는 동결건조오디나 열풍건조 오디에 비하여 생오디에서 그 효과가 두드러짐을 알 수 있었다. 2. 생오디의 첨가수준이 높을수록 pH 저하와 산생성의 증가가 빨라 발효촉진의 효과를 보였으며, 유산균수도 첨가수준이 높을수록 증가하였다. 3. 생오디 요구르트는 대조군에 비하여 유리당중의 fructose가 증가되었다. 4. 생오디 요구르트에서 lactic acid 함량은 대조군에 비하여 오디의 첨가량이 많을수록 더욱 증가되었다. 5. 생오디 요구르트의 관능검사 결과 외관(color), 맛(taste) 및 전체적인 기호도(overall acceptability)에서 유의적 차이를 보였으며, 향기(oder)와 조직감(texture)에서도 0.3%, 0.6% 처리구에 비하여 0.9%처리구가 좋은 결과를 보여 오디첨가요구르트의 제조 가능성을 보여주었다. 6. 생오디 요구르트의 저장실험 결과, 5℃에서 15일간 저장시 0.9% 오디첨가요구르트는 pH 4.04, 산도 1.082로 나타났고, 유산균수는 1.9×10^9cfu/ml로 우리나라의 호상 요구르트 총 유산균수 기준치 1.0×10^8cfu/ml를 초과하여 제품으로서의 우수성을 확인 할 수 있었다. This experiment was carried out to examine the fermentation properties of yogurt added fresh mulberry, freeze dried-mulberry and heated air dried-mulberry at concentrations of 0%, 0.3%, 0.6% and 0.9%. Lactic acid bacteria was used mixed starter culture(Str.salivarius ssp. thermophilus and Lac. delbrueckii ssp. bulgaricus). We obtained excellent results from the yogurt added fresh mulberry. In yogurt added 0.9% fresh-mulberry, lactic acid contents and titratable acidity were higher than those of 0%, 0.3%, 0.6% fresh-mulberry added. Also, sensory scores of color, taste and overall acceptability of the yogurt with 0.9% fresh mulberry was higher than those of any other groups.

한국인에서 혈소판 당단백 Ⅲa 유전자 다형성과 급성 관동맥 증후군의 관계

김광일,채인호,김효수,손대원,오병희,이명묵,박영배,최윤식,이영우 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.5