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Koh Myeongseok,Lee Jong Yoon,Han Song-Hee,Jeon Seong Woo,Kim Su Jin,Cho Joo Young,Kim Seong Hwan,Jang Jae Young,Baik Gwang Ho,Jang Jin Seok 거트앤리버 소화기연관학회협의회 2023 Gut and Liver Vol.17 No.2
Background/Aims: Endoscopic submucosal dissection is a widely used treatment for gastric epithelial neoplasms. Accurate delineation of the horizontal margins is necessary for the complete resection of gastric epithelial neoplasms. Recently, image-enhanced endoscopy has been used to evaluate horizontal margins of gastric epithelial neoplasms. The aim of this study was to investigate whether I-SCAN-optical enhancement (I-SCAN-OE) is superior to chromoendoscopy in evaluating the horizontal margin of gastric epithelial neoplasms. Methods: This was a multicenter, prospective, and randomized trial. The participants were divided into two groups: I-SCAN-OE and chromoendoscopy. For both groups, we first evaluated the horizontal margins of early gastric cancer or high-grade dysplasia using white-light imaging, and then evaluated, the horizontal margins using I-SCAN-OE or chromoendoscopy. We devised a unique scoring method based on the pathological results obtained after endoscopic submucosal dissection to accurately evaluate the horizontal margins of gastric epithelial neoplasms. The delineation scores of both groups were compared, as were the ratios of positive/negative horizontal margins. Results: In total, 124 patients were evaluated for gastric epithelial neoplasms, of whom 112 were enrolled in the study. A total of 112 patients participated in the study, and 56 were assigned to each group (1:1). There was no statistically significant difference in the delineation scores between the groups (chromoendoscopy, 7.80±1.94; I-SCAN-OE, 8.23±2.24; p=0.342). Conclusions: I-SCAN-OE did not show superiority over chromoendoscopy in delineating horizontal margins of gastric epithelial neoplasms.
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Walter Foreman,Soojeong Lee,Myeongseok Ko,Sangchul Bae,Sanghoon Han 한국산학기술학회 2012 SmartCR Vol.2 No.5
The purpose of this study was to determine the effect of an educational game with a situated learning strategy on the writing abilities of Korean elementary school students. With regard to writing abilities, this study focuses on the accuracy and fluency of English writing. Two research questions in this study are as follows: 1) Is there a significant difference in the English writing accuracy between an educational game group with a situated learning strategy and one without it? 2) Is there a significant difference in the English writing fluency between an educational game group with a situated learning strategy and one without it? This study used quantitative methods to evaluate the use of situated and non-situated learning strategies with an educational game. The research findings are as follows: First, there was no statistically significant difference between the experimental and control groups in the English writing accuracy test. Second, there was a statistically significant difference between the experimental and the control groups in the English writing fluency test. In sum, when an educational game is more situated, it can increase English writing fluency in elementary English writing. Thus, an educational game in elementary English with a situated learning strategy offers benefits for the growth of English writing fluency.
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( Seung Hyun Lee ),( So Ra Oh ),( Yeon Jin Cho ),( Jung-woo Park ),( Myeongseok Han ),( Jong Woon Bae ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-
Objective: Comparing conventional radical hysterectomy (CRH) and nerve-sparing radical hysterectomy (NSRH), about 1. Primary outcomes Postoperative outcomes (especially, Duration of postoperative catheterization) 2. Secondary outcomes Radicality and oncologic outcomes (disease free survival rate and overall survival rate in stage IA2-IIA) Methods: 1. Electronic searches using MEDLINE, Embase and CENTRAL. 2. Inclusion criteria: Studies reporting data of patients affected by cervical cancer 3. Exclusion criteria: Non cervical cancer (e.g. endometrial cancer), Case reports and only abstracts, Impossible data extraction 4. 24 studies were analysed using RevMan version 5.3 software [Risk ratios (RRs). Weighted mean differences (WMDs)] Results: 1. Operating time: WMD, 8.45 minutes ; 95% CI (-2.79 to 19.67); p = 0.14 2. Blood loss: WMD, -87.29 mL; 95% CI (-139.91 to -34.66); p = 0.001 3. Complications: RR, 0.61; 95% CI, 0.49 to 0.76; p < 0.0001 4. Duration of postoperative catheterization: WMD, -8.59 days; 95% CI (-12.17 to -5.02); p < 0.00001 5. Length of hospital stay: WMD, -5.37 days; 95% CI (-8.08 to -2.67); p < 0.0001 6. Resected parametrial length: WMD, -0.78 cm; 95% CI (-1.45 to -0.11); p = 0.02 7. Resected vaginal length: WMD, -0.12 cm; 95% CI (-0.27 to 0.02); p = 0.09 8. 5 year DFS (stage Ia2 IIa): RR, 0.98; 95% CI, 0.90 to 1.06; p = 0.62 9. 5 year OS (stage Ia2 IIa): RR, 0.97; 95% CI, 0.92 to 1.02; p = 0.26 Conclusion: 1. Operating time is similar in two groups 2. Duration of postoperative catheterization, LOS, complication, EBL, urinary, rectal sexual dysfunctions are significantly lower in NSRH. 3. Radicality is significantly inferior in NSRH. 4. Oncological safeties (2, 3, 5 DFS and OS) are similar in two groups. 5. CRH lowers QoL with bladder, rectal, sexual dysfunctions. 6. More radicality in CRH could not guarantee oncological safety in this study. 7. NSRH is not myth but histologically proven. 8. More RCTs should be conducted to strengthen the superiority and safety of NSRH in early stage cervical cancer. Acknowledgements: This work was supported by Dong-A University
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