http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Impact of Liver Fibrosis on Long-Term Outcome in Ischemic Stroke Patients
( Seung Up Kim ),( Minyoul Baik ),( Sungwoo Kang ),( Hyung Jong Park ),( Hyo Suk Nam ),( Ji Hoe Heo ),( Beom Kyung Kim ),( Jun Yong Park ),( Do Young Kim ),( Sang Hoon Ahn ),( Kwang-hyub Han ),( Young 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: To investigate whether there are differences in long-term all-cause and cardiovascular mortality by the burden of liver fibrosis or steatosis in patients with ischemic stroke or transient ischemic attack (TIA). Methods: Consecutive patients with acute ischemic stroke or TIA, who underwent transient elastography (TE) from January 2014 to December 2014, were considered eligible. The influence of liver fibrosis or steatosis, assessed using TE, on long-term outcomes was investigated using Cox proportional hazard models. Results: Among 395 patients included in this study, there were 37 (9%) patients with significant fibrosis (>8.0 kPa) and 164 (41.5%) patients with fatty liver (>250 dB/m). During the follow-up (median 2.7 years), all-cause and cardiovascular mortality occurred in 28 (7.1%) and 20 (5.1%) patients. On multivariate analyses, significant liver fibrosis was independently associated with increased risk of all-cause (HR 8.14, 95% CI 3.03-21.90, P< 0.001) and cardiovascular (HR 4.04, 95% CI 1.17-13.98, P=0.028) mortality, whereas fatty liver was not (all > p 0.05) Conclusions: This study demonstrated that the burden of liver fibrosis, not steatosis assessed on TE was an independent predictor of all-cause and cardiovascular mortality during long-term follow-up in patient with ischemic stroke.