Cancer Risk in Patients with Intestinal Behçet’s Disease: A Nationwide Population-Based Study

( Minkyung Han ),( Yoon Suk Jung ),( Won Ho Kim ),( Jae Hee Cheon ),( Sohee Park ) 대한간학회 2018 Gut and Liver Vol.12 No.4

Background/Aims: The relationship between intestinal Behçet’s disease (BD) and cancer remains unclear. We conducted a nationwide, population-based study to determine the risk of cancer in patients with intestinal BD. Methods: Using the National Health Insurance claims records, we collected data on 365 patients who had been diagnosed with intestinal BD between 2011 and 2014. Standardized incidence ratios (SIRs) of overall and site-specific cancers in patients with intestinal BD in comparison with the general population were calculated. Results: Among 167 men with intestinal BD, four cases of cancer were observed; among 191 women with BD, eight cases of cancer were observed. The risk of all cancers was significantly higher in women with intestinal BD than in women of the general population (SIR, 4.27; 95% confidence interval [CI], 1.84 to 8.41). However, in men with intestinal BD, the risk of all cancers was not significantly higher than that in men of the general population (SIR, 2.08; 95% CI, 0.57 to 5.33). The risk of hematologic cancer was significantly higher in both men and women with intestinal BD than in their counterparts in the general population (SIR, 23.90; 95% CI, 2.89 to 86.32 in men; SIR, 34.47; 95% CI, 4.17 to 124.51 in women). In particular, patients with intestinal BD showed a higher risk of leukemia and myelodysplastic syndrome than the general population. Conclusions: Patients with intestinal BD demonstrated a higher risk of hematologic cancer, especially leukemia, than the general population. Furthermore, women with intestinal BD showed a higher risk of all cancers. (Gut Liver 2018;12:433-439)

아동의 어휘발달 촉진을 위한 언어입력환경으로서의 동화책 어휘 연구: 용언을 중심으로

한민경(MinKyung Han),성시연(SiYeon Seong),최서진(SouJin Choi) 한국언어청각임상학회 2016 Communication Sciences and Disorders Vol.21 No.1

본 연구에서는 동화책에 사용되는 어휘 중 용언의 유형과 사용빈도 등 그 형태적 특징을 알아보고 동화책에 등장하는 용언의 활용방안을 모색하고자 하였다. 방법: 0-2세, 3-4세, 5-7세용 동화책 각 연령대에서 선정한 26권씩 총 78권의 동화책에 등장하는 총 14,728어절 중 동사, 형용사, 보조동사, 보조형용사, 긍정지정사, 부정지정사 등 용언에 해당되는 5,388어절의 품사별 유형 수와 사용빈도를 계산하고, 연령별 유형 수와 사용빈도의 차이를 살펴보았다. 결과: 동화책에 등장하는 용언은 동화책에서 사용되는 어휘 전체 유형 수의 25.9%, 어휘 전체 사용빈도의 18.7%를 차지하였고, 동화책 대상 연령이 높을수록 유형 수와 사용빈도가 증가하였다. 품사별 유형 수는 동사>형용사>보조동사>보조형용사>긍정지정사=부정지정사의 순서로 많았고, 사용빈도는 동사>형용사>보조동사>긍정지정사>보조형용사>부정지정사의 순서로 높았다. 동화책 대상 연령이 높을수록 동사는 유형 수와 사용빈도가 유의미하게 증가하였으나, 형용사는 유형 수와 사용빈도가 모두 유의미하게 감소하였고, 보조용언은 유형 수는 유의미하게 감소하나 사용빈도는 유의미하게 증가하였다. 논의 및 결론: 동화책에서 사용되는 용언 품사 중 동사와 보조동사의 경우 동화책 대상 연령이 높아질수록 다양한 종류가 빈번하게 사용되는 것으로 나타나 동화책은 아동의 구문발달에 긍정적인 영향을 미치는 언어입력환경을 제공하는 것으로 보인다. Objectives: The purpose of this study was to investigate the characteristics of the types and tokens of predicates in storybooks and to provide suggestions on the use of storybook predicates in research and clinical practice. Methods: Twenty-six books from each age group of 0-2, 3-4, and 5-7 years were selected, totaling 78 storybooks. Morphological analysis was conducted on 5,388 utterances containing predicates including verbs (Verb), adjectives (Adj), auxiliary verbs (Aux Verb), auxiliary adjectives (Aux Adj), positive copular (P Copula), and negative copula (N Copula) in order to calculate the types and tokens of predicates across word classes and to determine the differences in the types and tokens of each word class across storybook age groups. Results: In the selected storybooks predicates repre¬sented 25.9% and 18.7% of the total types and tokens, respectively, with types and tokens increasing with age. The order of types from greatest to smallest across word classes was Verb>Adj>Aux Verb>Aux Adj>P Copula=N Copula and the frequency of tokens was Verb>Adj>Aux Verb>P Copula>Aux Adj >N Copula. Across storybook age groups both type and token frequency for verbs increased significantly with age and decreased signifi¬cantly for adjectives, and for auxiliary predicates the types decreased significantly with age whereas the token frequency increased significantly with age. Conclusion: Results show that the type and token frequency of verbs and auxiliary verbs increases with age in these storybooks. Thus, storybooks provide a language input environment that may positively influence syntactic development in children.

에스테렐 프로그램 디버깅을 위한 테스트 데이터 자동 생성

윤정한(Jeong-Han Yun),조민경(Minkyung Cho),서선애(Sunae Seo),한태숙(Taisook Han) 한국정보과학회 2009 정보과학회논문지 : 소프트웨어 및 응용 Vol.36 No.10

Esterel is an imperative synchronous language that is well-adopted to specify reactive systems. Programmers sometimes want simple validations that can be applied while the system is under development. Since a reactive system reacts to environment changes, a test data is a sequence of input events. Generating proper test data by hand is complex and error-prone. Although several test data generators exist, they are hard to learn and use. Mostly, system designers need test data to reach a specific status of a target program. In this paper, we develop a test data generator to generate test input sequences for debugging Esterel programs. Our tool is focused on easy usage; users can describe test data properties with simple specifications. We show a case study in which the test data generator is used for a practical development process. 에스테렐은 반응형 시스템 설계에 적합하도록 디자인 된 명령형 동기언어이다. 시스템 개발 시에는 디버깅을 위해 다양한 테스트가 필요하다. 반응형 시스템을 테스트 하려면 일련의 입력을 시간의 흐름에 따라 순서대로 나열하여야 한다. 하지만 원하는 목적에 적합한 테스트 데이터를 생성해 주려면 많은 노력이 필요하며, 이 과정에서 오류가 발생하기도 한다. 따라서 디버깅의 특성상 빠르면서 원하는 목적의 테스트 데이터를 쉽게 표현할 수 있는 도구가 필요하다. 본 연구에서는 디버깅에 도움을 줄 수 있는 테스트 데이터 자동 생성기를 개발하였다. 본 연구는 개발자가 원하는 테스트 데이터를 쉽게 표현할 수 있고, 빠르게 테스트 데이터를 만들어내는 것에 초점을 두었다. 또한 사례 연구를 통해 실제 시스템 개발에 우리의 테스트 데이터 생성기를 적용한 예를 보여준다.

Ketamine Inhibits Ultrasound Stimulation-Induced Neuromodulation by Blocking Cortical Neuron Activity

Han, Sungmin,Kim, Minkyung,Kim, Hyungmin,Shin, Hyunjoon,Youn, Inchan Elsevier 2018 Ultrasound in medicine & biology Vol.44 No.3

<P><B>Abstract</B></P> <P>Ultrasound (US) can be used to noninvasively stimulate brain activity. However, reproducible motor responses evoked by US are only elicited when the animal is in a light state of anesthesia. The present study investigated the effects of ketamine on US-induced motor responses and cortical neuronal activity. US was applied to the motor cortex of mice, and motor responses were evaluated based on robustness scores. Cortical neuronal activity was observed by fluorescence calcium imaging. US-induced motor responses were inhibited more than 20 min after ketamine injection, and US-triggered Ca<SUP>2+</SUP> transients in cortical neurons were effectively blocked by ketamine. Our results indicate that ketamine suppresses US-triggered Ca<SUP>2+</SUP> transients in cortical neurons and, therefore, inhibits US-induced motor responses in a deep anesthetic state.</P>

안동지역 사과원에 발생하는 식물기생선충상 조사

한상찬,최광준,김준혁,김병희,윤상부,허재원,곽민경 安東大學校 農業科學技術硏究所 1998 農業科學技術 硏究論文集 Vol.5 No.-

사과원의 식물기생선충상을 조사하여 사과생산에 문제를 일으키는 선충 파악과 그 관리 방법을 규명코자 안동시 길아면.일직면.풍산읍.풍천면의 사과원 398개소(1084ha)에서 시료를 채취, 선충을 분리하였다. 그 시료를 검정한 결과 Aphelenchoides, Aphelenchus, Criconemoides, Cryphodera, Helicotylenchus, Hemicycliophora, Meloidogyne, Paratylenchus, Pratylenchus, Tylenchorhynchus, Tylenchidae, Tylenchus, Trichodorus, Xiphinema등 14개속의 기생선충이 검출되었다. 이들 중 Tylenchorhynchus (29.37%), Pratylenchus (10.05%), Hemicycliophora (5.11%), Meloidogyne (4.47%), trichodorus (2.86%), and Xiphinema (2.18%)를 차지하여 사과원의 주요 기생선충으로 인정되었다. Plant-parasitic nematodes in apple archards were sampled and classified to understand their fauna. Samples were obtained in 398 sites (ca. 1084ha) in Andong area including Kilan, Iljik, Poongsan, and Pungchun. Fiffteen geni were identified : Aphelenchoides, Aphelenchus, Criconemoides, Cryphodera, Helicotylenchus, Hemicycliophora, Meloidogyne, Paratylenchus, Pratylenchus, Tylenchorhynchus, Tylenchidae, Tylenchus, Trichodorus, and Xiphinema. Dominant geni represented Tylenchorhynchus (29.37%), Pratylenchus (10.05%), Hemicycliophora (5.11%), Meloidogyne (4.47%), trichodorus (2.86%), and Xiphinema (2.18%).

WO₃/NiO 상호 보완적인 구조의 전고체 전기변색 필름

신민경 ( Minkyung Shin ),이선희 ( Sun Hee Lee ),서인태 ( Intae Seo ),강형원 ( Hyung-won Kang ),한승호 ( Seung Ho Han ) 한국전기전자재료학회 2022 전기전자재료학회논문지 Vol.35 No.3

An all-solid-state electrochromic film was fabricated by laminating tungsten oxide (WO₃) and nickel oxide (NiO) thin films deposited by a reactive DC magnetron sputtering on flexible ITO films. The influence of oxygen partial pressure on the crystal structure, microstructure, optical properties, and electrochromic properties of WO₃ and NiO thin films were investigated. WO₃ and NiO films showed the best electrochromic properties under the flow of Ar:O₂=80:20 and Ar:O₂=90:10, respectively. The EC film fabricated with an optimized WO₃ and NiO films showed a high coloration efficiency, a fast response time, and a stable optical modulation. It is expected that flexible EC window films will pave the way for the next-generation energy-saving windows.

새떼 알고리즘을 이용한 무선 메쉬 네트워크 내 시간 동기화 기법에 관한 연구

김민경(MinKyung Kim),한기림(Kireem Han),최준균(Junkyun Choi) 한국통신학회 2017 한국통신학회 학술대회논문집 Vol.2017 No.11

Effects of Drip Irrigation Volumes on Plant Growth and Yield of Tomato Grown in Perlite

Doo Han Kim(김두한),Md Rayhan Ahmed Shawon(라이한 샤원),Jin Hee An(안진희),Hyoun Jin Lee(이현진),Yun-Jae Lee(이윤재),Minkyung Kim(김민경),Yong-Beom Lee(이용범),Ki Young Choi(최기영) (사)한국생물환경조절학회 2022 생물환경조절학회지 Vol.31 No.4

가변 배기 머플러의 밸브 개폐에 따른 내부 유동 특성 비교

한성현(SungHyun Han),조범지(Beomji Jo),박민경(Minkyung Park),조영수(Yungsoo Cho) 한국자동차공학회 2017 한국자동차공학회 부문종합 학술대회 Vol.2017 No.5

The Role of Bone Scintigraphy in the Diagnosis of Rheumatoid Arthritis According to the 2010 ACR/EULAR Classification Criteria

김지영,조수경,Minkyung Han,최윤영,배상철,성윤경 대한의학회 2014 Journal of Korean medical science Vol.29 No.2

We aimed to investigate the role of bone scintigraphy (BS) in the diagnosis of rheumatoid arthritis (RA) as a supplement to the 2010 American College of Rheumatology (ACR)/ European League Against Rheumatism (EULAR) criteria. A total of 156 patients who underwent BS with screening laboratory to confirm RA were enrolled. We divided them into two groups according to the presence of arthritis upon the first physical examination, and evaluated the diagnostic validity of BS as an independent (BS only) or assistant diagnostic tool using the 2010 criteria (BS-assisted). Seventy-five patients had active arthritis (Group I), while the remaining 81 patients did not (Group II). Among them, 56 patients in group I and 5 patients in group II were finally classified as RA. In the group I patients who were eligible for application of the 2010 criteria, the sensitivity of the BS only and BS-assisted diagnosis was not superior to that of the 2010 criteria. However, BS-assisted diagnosis showed high positive prediction values in group I patients with 2010 criteria score <6 and group II patients. Therefore, BS is still helpful to detect RA even after the introduction of the 2010 criteria, especially among patients who do not satisfy the 2010 criteria as well as those who are ineligible for the 2010 criteria due to dubitable arthritis at clinical presentation.