알코올의 섭취가 흰쥐의 혈액과 간의 지질대사에 미치는 영향

이명숙,김영연,김효숙,김매하,전진순,서진숙,송선미,양영재,윤원손,이미라,이효영,정승현 誠信女子大學校 生活文化硏究所 2004 生活文化硏究 Vol.18 No.-

To investigate the effects of ethanol on the lipid metabolism in blood and liver, twenty one male Sprague Dawley rats had orally taken the 25% alcohol and 50% alcohol by 5g per Kg of weight during 3 weeks after the adjusting period. For the energy balance, 85% sucrose and 45% sucrose was added in control group and 25% alcohol group each. The weight was reduced by alcohol treatment according to the levels, otherwise the weight of liver and heart was little increased in alcohol groups rather than in control without significance. Moreover, RBC, WBC, hemoglobin and hematocrit were increased by alcohol treatment according to the levels without significance. Otherwise, adjusted bilirubin levels by 100g of weight was significantly increased by alcohol treatment dose dependently. Alcohol induced RBC degradation and increased circulated bilirubin because of liver damage. For blood lipid profiles, blood cholesterol was increased in 50% of alcohol group compared to that of 25% and control groups, otherwise, blood triglycerides (TG) was increased by 30% in 25% alcohol groups rather than in control but not significantly different. The hepatic lipid composition, cholesterol levels in alcohol treatment groups was lower than those in control. The hepatic TG was not influenced by alcohol treatment. The two reasons of decreasing hepatic lipids were suggested by 85% sucrose of control for energy balance more synthesized cholesterol and TG than those in 25 or 50% alcohol groups, and by cholesterol and TG could not be synthesized because of liver damage from alcohol.

한국전통생활문화에 관한 고찰

이숙,홍윤호,신윤숙,신효식,한경미,최정미,김은정 全南大學校家政科學硏究所 2002 生活科學硏究 Vol.12 No.-

This study is objected on preliminary research for more scientific and wider studies on the Traditional Living Culture of Korea. For this purpose, studies about clothing, food, home management, Traditional Living Culture were reviewed and analysed. The results were as follows : First, Clothing culture studies concentrated on ritual clothings, Second, Food Culture studies included history of traditional food development and recipes. Third, in the field of home management value system, attitudes and parent-child relations were studied,

연구 여성 문학 : 몸과 기억의 현상학 : 윤정모의 『 고삐 』 읽기

김정자(Jung Ja Kim),정미숙(Mi Sook Jung) 부산대학교 여성연구소 2000 여성학연구 Vol.10 No.1

N/A

퍼머넌트와 염색 연결시술시 정향트리트먼트 적용시점에 따른 모발보호효과

박미나ㆍ정지영ㆍ고경숙(Mi na ParkㆍJee Young JungㆍKyoung sook Ko) 한국인체미용예술학회 2016 한국인체미용예술학회지 Vol.17 No.1

This study attempted to determine the effects of hair protection by investigating the characteristics and possibilities of hair cosmetics using the hot water extracts of Syzygium aromaticum and then hair-protection effects were confirmed through pre-treatment and post-treatment at consecutive chemical treatments. At the consecutive chemical treatments, the general treatment was divided into pretreatment(N1) and general treatment post-process(N2). Then, the Syzygium aromaticum-based treatment was divided into pre-treatment(J1) and post processing(J2). According to the analysis, tensile strength was the highest in the Syzygium aromaticum extract treatment group. At consecutive treatments, ‘J2’ which processed treatment for Syzygium aromaticum, was the highest. In terms of hair thickness, the Syzygium aromaticum group was greater than the general treatment group. When measured to determine the morphological characteristics of ‘Hair’ at 20,000 magnifications using SEM, the Syzygium aromaticum extract post-treatment group (J2) revealed the highest value (373.98±10.83㎚). Regarding hair composition under the EDS, Syzygium aromaticum extract post-treatment group was the highest with 07.77% interms of sulfur content. The results confirmed that Syzygium aromaticum extract treatment is extremely effective in easing hair damage which is caused by consecutive dyeing after permanent. Therefore, the Syzygium aromaticum extract treatment would be effective in preventing hair damage and keeping hair healthy and glossy.

암 병동 간호사의 통증관리에 대한 지식과 태도

공성화,방찌야,서민숙,현신숙,김희정,이미애1,이미애2,유현희,허재경,김은애,박경숙 성인간호학회 2004 성인간호학회지 Vol.16 No.1

Purpose: The purpose of this study is to evaluate the knowledge and attitudes of oncology ward nurses toward cancer pain management and to find ways to improve the educational program for nurses. Method: A total of 209 nurses working at the oncology ward of three hospitals in Seoul and a Gyenggi Province. The survey instrument used was the 32-item scale for evaluating nurses knowledge and attitudes originally developed by McCaffery and Ferrell'(1990). that was by Kim'(1997). Result: In terms of the nurses knowledge of pain management. the result showed that the nurses scored an average of 67.8 out of 100 for phamacokinetics of opioids. 84.8 for classification of analgesics, 60.1 for pain assessment, and 70.7 for drug administration. 18.2% of the nurses hesitate to inject the narcotic agent because of concerns regarding the drug's potential side effects. there was significant difference in the knowledge of pain management according to the general characteristics of pain in terms of the nurses age(p=.001), position (p=.016). years of experiences(p=.002), experience of cancer pain education(p= .001). Conclusion: The also showed that nurses working at cancer ward lack knowledge. It is important to provide intensive education to nurses about cancer pain management.

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

발열을 동반한 호중구감소증에서 Cefepime 단독투여와 Ceftazidime 및 Tobramycin 병합투여의 효능비교

정현욱,채제욱,강미라,양정채,문치숙,기현균,장현하,오원섭,김기현,백경란,이남용,송재훈 대한감염학회 2004 감염과 화학요법 Vol.36 No.6

목적 : 국내에서 발열을 동반한 호중구감소증이 있는 악성 종양환자에게 경험적 항생제로 베타락탐계 항생제와 아미노배당체의 병합요법의 사용이 일반적이다. Cefepime은 광범위 항균 작용을 가지고 있어, 그람 음성균 뿐만 아니라 그람 양성균에 대해서도 우수한 효과를 나타낸다. 재료 및 방법: 발열을 동반한 호중구감소증이 있는 악성 종양환자를 대상으로 무작위, 공개, 비교 연구를 시행하였다. 대상 환자를 무작위로 cefepime 단독요법군과 ceftazidime 및 tobramycin 병합요법군으로 나누어 투여하고 각각의 임상적 효능과 안전성을 비교하였다. 구강및 인후 점막염이 있는 환자에서 분리된 녹색 연쇄알 구균에 대한 항생제 내성 정도를 조사하였다. 결과 : 대상환자 89명 중 CA 투여군이 48예(53.9%), CT 투여군이 41예(46.1%)이었다. 발열의 유형별로 MDI는 18예(20.2%), CDI는 9예(10.1%), UF는 62예(69.7%)로 두 군 간에 차이가 없었다. CA 투여군과 CT 투여군의 임상적 호전률은 시험약 투여 후 2-4일째 각각 91.7%, 85.4% (P=0.31), 치료 종료 시 각각 91.7%, 100% (P=0.15)로 두 군간에 유의한 차이가 없었다. 치료 종료 시 CA 투여군과 CT 투여군의 세균학적 소실률은 모두 100%로 두 군간의 유의한 차이가 없었다(P=0.78). 점막염이 있는 환자로부터 녹색 연쇄알 구균이 분리된 경우는 25예(28.1%)이었으며, 분리된 녹색 연쇄알 구균은 penicillin, ceftriaxone, cefepime, vancomycin에 모두 감수성을 보였다. 약제 관련 이상 반응의 발생 빈도도 두 군간에 유의한 차이가 없었다. 결론 : 발열을 동반한 호중구감소증이 있는 악성 종양환자의 경험적 항생제로서 cefepime 단독요법은 ceftazidime 및 아미노배당체의 병합요법만큼 효과적이고 안전하였다. Background : Broad-spectrum antibiotic therapy has been recommended as an empirical regimen in cancer patients with febrile neutropenia. Cefepime is a fourth generation cephalosporin with good activity against both gram-positive cocci and gram-negative bacilli. Materials and Methods : To compare the efficacy and safety of cefepime alone with ceftazidime plus tobramycin as empirical regimen for adult cancer patients with febrile neutropenia, a randomized, open label, comparative trial was performed. If the patient showed clinical improvent 72 hours, antibiotic could be changed to oral ciprofloxacin. Clinical and microbiological responses were determined at 72 hours and at the end of therapy. To investigate the antimicrobial resistance of viridans streptococci, swab cultures were obtained from throat in all enrolled patients and antimicrobial susceptibility tests were performed by using microdilution method according to the NCCLS. Results : A total of 89 patients were enrolled. Forty-eight patients received cefepime alone (CA), and 41 patients received ceftazidime plus tobramycin (CT). Demographic and baseline clinical characteristics were similar in both groups (P>0.05). The initial clinical success rate at day 2-4 in group CA (91.7%) was similar with that in CT group (85.4%) (P=0.31). At the end of therapy, the final clinical success rate in CA group (91.7%) was similar to that in CT group (100%) (P=0.15). In 18 patients, with microbiologically defined infections, the eradication rate was 100% in both groups. Adverse events including liver dysfunction (21.3%) and renal dysfunction (2.2%), were similar in both groups (P=0.87). Viridans streptococci were isolated from the throat cultures in 25 cases, and all of these strains were susceptible to penicillin (MIC_(90) 0.12 ㎍/mL), cefepime (1 ㎍/mL), and vancomycin (0.12 ㎍/mL). Conclusion : Efficacy and safety of cefepime monotherapy was comparable to the combination of ceftazidime and tobramycin. It could be used as an alternative empirical regimen for treating cancer patients with febrile neutropenia.

性敎育이 女高生의 性에 對한 知識 및 態度에 미친 效果

정문숙,방미라 慶北大學校 醫科大學 1991 慶北醫大誌 Vol.32 No.2

본 조사는 인문계 여고생 2학년에게 연구자가 정규적으로 주1시간 총 24시간에 걸쳐 성교육을 지침서에 의거, 실시하고 1학년과 교육을 주지 않은 2학년 여고생과 비교하여 성에 대한 지식 및 태도에 준 효과를 설문지를 배부 후 회수하여 본 결과는 다음과 같다. 대상은 경남 지역 1개교 542명을 교육군으로, 1학년 164명 그리고 비교육군 2학년 972명을 대상으로 하였으며 설문기간은 1988년 12월 21일부터 23일까지 3일간이었다. 대상 여학생의 70.8%는 부모와 성문제를 상담하지 않았으며, 98.5%가 성교육이 필요하다고 응답하였다. 적절한 성교육 시기로 전체의 56.0%가 중학교라고 응답했으며 성지식의 출처로 선생님으로부터가 교육군의 30.1%인데 비해 비교육군은 19.1%로 양군간 유의한 차를 보였다(p<0.01). 성에 관련된 인간의 해부 생리 및 2차 성징, 성병, 피임 및 임신 생리 등의 지식의 정도를 1학년의 평균치를 기준으로 보았을 때 교육군은 평균치 이상인 여고생이 100.0%이었고 비교육군에 비해(54.3%, 76.3%, 75.1%) 유의하게 높은 비율이었다(p<0.01). 성에 대한 긍정적 태도, 혼전 성관계와 인공유산에 대한 바른 태도 및 가족계획 슬로건에 대한 긍정적 태도는 교육군과 비교육군간 찬성유무 및 생각해 본 일이 없다는 무관심 유무에서 유의한 차를 나타냈다(p<0.05, p<0.01). 고등학교 시절의 이성교제, 이성교제에 대한 지식, 친구, 부모, 선생님과의 자유로운 대화에 대한 찬성율이 교육군과 비교육군간 유의한 차(p<0.05, p<0.01)가 있었으며 생각해 본 일이 없다는 항목은 비교육군이 교육군보다 유의하게 높았다. This study was attempted to assess the effects of a long term regular sex education on the knowledge about anatomy and physiology of human reproductive organs and the attitude toward sex of second grade high school girls. The study population included 1,678 high school girls(542 educated second grade grils, 972 not educated second grade girls and 164 pre-educated first grade girls) attending in 3 high schools located in Kyungnam province. The data was collected by guestionnaire to assess knowledge of sexual anatomy and physiology and the attitude toward sex from 21 to 24 December 1988. The results were as follows: Most of students(educated group 99.3%, not educated group 98.1%) agreed to necessity of sex education. Among students 70.8% did not talk about their sexual problems with their parents and 30.1% of educated group obtained sexual knowledge from their teachers. There were significant differences between level of knowledge on anatomy and physiology of reproductive organs, secondary growth spurt, VD, pregnancy and contraceptives of educated group and not educated group(p<0.01). There was significant difference between positive attitude about sexual intercourse before marriage, artificial abortion and family planning slogan of educated group and not educated group(p<0.05, p<0.01). There were significant differences between degree of agreement about acquaintance with the other sex, knowledge of acquaintance with the other sex, talk freely with friend, parent and teacher of educated group and not educated group(p<0.05, 0<0.01). Statistics revealed that high school girls of not educated group had less knowledge about acquaintance with the other sex than educated group(p<0.01).

三陟地域의 Karst Terrain 에 關한 硏究

鄭美淑 건국대학교 1980 論文集 Vol.12 No.1

The limestones forming the Karst Terrain in the Korean Peninsula are belong to Cambro-Ordovician, so called Choseon System. They are distributed widely in the Pyeongan Geosyncline and Ogcheon Geosyncline, but in this paper is discussed only Ogcheon Geosyncline. The Karst Phenomena found in this layer are terra rossa, lapie´s, doline, uvala, hum, and karst spring etc. There are a half of dedekte karst in the area, therefore lapie´s and terra rossa are many found. The conspicous karst phenomena are at the mercy of the geologic structure, quality of limestones, landform, and a head of water between local base level of the level of sinkhole terrain. Dolines are very development but uvala is not found or a little. The density of the dolines on the sinkhole terrain(the number of the sinkholes in square kilometer) are 70 to 50. In Yeondang and Hwedongri Region, it is consider that the formation of the doline were developed a after gravelly deluvial deposits, it's age may be Wu¨rm Ice Age to Postglacial Age. A study on the cycle Karst topography by the cvijic, the karst cycle corresponds to the full mature and late mature to the early old stage.

소아 간질환자에서 혈중 Carbamazepine-epoxide 농도 및 이에 영향을 미치는 요인

정인숙,백정미,장인진,신상구 大韓臨床藥理學會 1998 臨床藥理學會誌 Vol.6 No.2