http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Korean treatment recommendations for patients with axial spondyloarthritis
( Mi Ryoung Seo ),( Jina Yeo ),( Jun Won Park ),( Yeon-ah Lee ),( Ju Ho Lee ),( Eun Ha Kang ),( Seon Mi Ji ),( Seong-ryul Kwon ),( Seong-kyu Kim ),( Tae-jong Kim ),( Tae-hwan Kim ),( Hye Won Kim ),( M 대한내과학회 2023 The Korean Journal of Internal Medicine Vol.38 No.5
We aimed to develop evidence-based recommendations for treating axial spondylarthritis (axSpA) in Korea. The development committee was constructed, key clinical questions were determined, and the evidence was searched through online databases including MEDLINE, Embase, Cochrane, KoreaMed, and Kmbase. Systematic literature reviews were conducted, quality of evidence was determined, and draft recommendations were formulated according to the Grading of Recommendations Assessment, Development, and Evaluations methodology. Recommendations that reached 80% consensus among a voting panel were finalized. Three principles and 21 recommendations were determined. Recommendations 1 and 2 pertain to treatment strategies, regular disease status assessment, and rheumatologist-steered multidisciplinary management. Recommendations 3 and 4 strongly recommend patient education, exercise, and smoking cessation. Recommendations 5-12 address pharmacological treatment of active disease using nonsteroidal anti-inflammatory drugs, glucocorticoids, sulfasalazine, biologics, and Janus kinase inhibitors. Recommendations 13-16 address treatment in stable disease. We suggest against spa and acupuncture as therapies (Recommendation 17). Recommendations 18 and 19 pertain to total hip arthroplasty and spinal surgery. Monitoring of comorbidities and drug toxicities are recommended (Recommendations 20 and 21). Recommendations for axSpA treatment in a Korean context were developed based on comprehensive clinical questions and evidence. These are intended to guide best practice in the treatment of axSpA.
Corrigendum: Korean treatment recommendations for patients with axial spondyloarthritis
( Mi Ryoung Seo ),( Jina Yeo ),( Jun Won Park ),( Yeon-ah Lee ),( Ju Ho Lee ),( Eun Ha Kang ),( Seon Mi Ji ),( Seong-ryul Kwon ),( Seong-kyu Kim ),( Tae-jong Kim ),( Tae-hwan Kim ),( Hye Won Kim ),( M 대한류마티스학회 2024 대한류마티스학회지 Vol.31 No.1
Corrigendum: Korean treatment recommendations for patients with axial spondyloarthritis
Mi Ryoung Seo,Jina Yeo,Jun Won Park,Yeon-Ah Lee,Ju Ho Lee,Eun Ha Kang,Seon Mi Ji,Seong-Ryul Kwon,Seong-Kyu Kim,Tae-Jong Kim,Tae-Hwan Kim,Hye Won Kim,Min-Chan Park,Kichul Shin,Sang-Hoon Lee,Eun Young L 대한내과학회 2024 The Korean Journal of Internal Medicine Vol.39 No.1
Case Reports : A Case of Enterocolic Lymphocytic Phlebitis Mimicking Surgical Abdomen
( Mi Ryoung Seo ),( Tae Eun Kim ),( Hee Jung Ryu ),( Han Joo Baek ),( Hyo Jin Choi ) 대한류마티스학회 2014 대한류마티스학회지 Vol.21 No.2
Vasculitis that involves the gastrointestinal (GI) tract often occurs as part of a systemic inflammatory process. It is a well-recognized manifestation of the small and medium sized vessel vasculitides. Vasculitis of the GI tract may occur in isolation; although it can progress to a systemic illness. It usually involves the arterioles, venules, and capillaries; however, it is very rare for only the venules to be affected. Enterocolic lymphocytic phlebitis is a localized vasculitis, typically affecting the small and medium-sized intramural and mesenteric veins of the intestines. We report a case of enterocolic lymphocytic phlebitis of the colon. A 38-year-old woman was presented with hematochezia and severe abdominal pain on the day of admission. She had no history of intestinal disease or systemic disease. Computed tomography showed an extremely thickened wall of the colon, along with several air bubbles in the colon with diffuse subcutaneous emphysema in the abdominal wall. An emergency exploration laparotomy and extended right hemicolectomy was performed. The patient recovered completely after surgery and remains well without further therapy.
Seo Mi Ryoung,Kim Gunwoo,Moon Ki Won,Sung Yoon-Kyoung,Yoo Jong Jin,Yoon Chong-Hyeon,Lee Eun Bong,Lee Jisoo,Kang Eun Ha,Kim Hyungjin,Park Eun-Jung,Uhm Wan-Sik,Lee Myeung Su,Lee Seung-Won,Choi Byoong Yo 대한의학회 2021 Journal of Korean medical science Vol.36 No.17
Background: There is increasing interest in the quality of health care and considerable efforts are being made to improve it. Rheumatoid arthritis (RA) is a disease that can result in favorable outcomes when appropriate diagnosis and treatment are provided. However, several studies have shown that RA is often managed inappropriately. Therefore, the Korean College of Rheumatology aimed to develop quality indicators (QIs) to evaluate and improve the health care of patients with RA. Methods: Preliminary QIs were derived based on the existing guidelines and QIs for RA. The final QIs were determined through two separate consensus meetings of experts. The consensus was achieved through a panel of experts who voted using the modified Delphi method. Results: Fourteen final QIs were selected among 70 preliminary QIs. These included early referral to and regular follow-up with a rheumatologist, radiographs of the hands and feet, early initiation and maintenance of disease-modifying anti-rheumatic drug (DMARD) therapy, periodic assessment of disease activity, screening for drug safety and comorbidities, including viral hepatitis and tuberculosis before biologic DMARD therapy, periodic laboratory testing, supplementation with folic acid, assessment of the risk for cervical spine instability before general anesthesia, patient education, and specialized nurse. Conclusion: These QIs can be used to assess and improve the quality of health care for patients with RA.
( Mi Ryoung Seo ),( Ji-won Kim ),( Eun-jung Park ),( Seung Min Jung ),( Yoon-kyoung Sung ),( Hyungjin Kim ),( Gunwoo Kim ),( Hyun-sook Kim ),( Myeung-su Lee ),( Jisoo Lee ),( Jian Hur ),( Bum Sik Chin 대한류마티스학회 2020 대한류마티스학회지 Vol.27 No.4
Patients with systemic rheumatic diseases (SRD) are vulnerable for coronavirus disease (COVID-19). The Korean College of Rheumatology recognized the urgent need to develop recommendations for rheumatologists and other physicians to manage patients with SRD during the COVID-19 pandemic. The working group was organized and was responsible for selecting key health questions, searching and reviewing the available literature, and formulating statements. The appropriateness of the statements was evaluated by voting panels using the modified Delphi method. Four general principles and thirteen individual recommendations were finalized through expert consensus based on the available evidence. The recommendations included preventive measures against COVID-19, medicinal treatment for stable or active SRD patients without COVID-19, medicinal treatment for SRD patients with COVID-19, and patient evaluation and monitoring. Medicinal treatments were categorized according to the status with respect to both COVID-19 and SRD. These recommendations should serve as a reference for individualized treatment for patients with SRD. As new evidence is emerging, an immediate update will be required. (J Rheum Dis 2020;27:218-232)
서미령 ( Mi Ryoung Seo ),백한주 ( Han Joo Baek ) 대한내과학회 2013 대한내과학회지 Vol.85 No.3
척추관절염은 천장관절염/척추염, 소수관절염, 부착부염같은 근골격 증상과 포도막염, 건선, 장점막 질환 및 HLA-B27유전자와의 연관성을 공유하고 있는 만성 염증성 류마티스질환이다. 척추관절염의 진단기준은 없지만 다양한 분류기준이 진단에 도움을 줄 수 있다. 최근 ASAS는 방사선학적 천장관절염이 보이지 않는 단계를 포함하여 포괄적이고 체계적으로 척추관절염을 분류할 수 있는 축형 및 말초형 척추관절염 분류기준을 제안하였다. 척추관절염은 유전 요소가 지배적인 질환이며 가장 강력한 연관 유전자는 HLA-B27이다. 최근 MHC 유전자 자리 바깥에 위치한 질환 감수성 유전자로 ERAP1, IL23R 등이 발견되었다. 척추관절염의 주요병리는 부착부의 염증과 골생성이다. 척추관절염의 염증 발생을 설명하기 위해 HLA-B27과 관련된 여러 기전이 제안 되었다. HLA-B27 이외의 질환 감수성 유전자 생성물들은 HLA-B27 분자의 과정이나 시토카인 경로에 관여할 것으로 추정된다. 한편 척추관절염의 골생성을 조절하는 염증 과정과는 완전히 혹은 부분적으로 분리된 기전이 존재한다. The spondyloarthritis (SpA) is a group of chronic inflammatory rheumatic diseases in association with HLA-B27. They share the clinical features including sacroiliitis, spondylitis, oligoarthritis, enthesitis and extra-articular involvement. Recently ASAS proposed new classification criteria sets of axial and peripheral SpA. They were designed to include non-radiographic SpA, thus can guide the early diagnosis of disease before the structural damage occurs. SpA has a strong genetic predisposition. Non-MHC genes, such as IL23R and ERAP1, as well as HLA-B27 were confirmed as susceptibility genes through several GWAS. Major pathology in SpA is entheseal inflammation and new bone formation. Intrinsic ability of HLA-B27 to trigger innate immune response and several proinflammtory cytokines may contribute to the inflammation in SpA. New bone formation could be explained by a mechanism, partly or completely independent of the inflammatory process. (Korean J Med 2013;85:229-239)
증례 : 류마티스 ; 클라인펠터 증후군(Klinefelter`s Syndrome)에서 동반된 류마티스관절염 1예
서미령 ( Mi Ryoung Seo ),조현정 ( Hyun Jung Cho ),최효진 ( Hyo Jin Choi ),백한주 ( Han Joo Baek ),안정열 ( Jeong Yeal Ahn ) 대한내과학회 2011 대한내과학회지 Vol.81 No.3
저자 등은 29세 남자에서 드문 활동성 류마티스관절염이 클라인펠터 증후군에 동반하여 발생한 국내 첫 증례를 경험하였다. 환자는 클라인펠터 증후군의 치료를 위해 지속적인 테스토스테론의 보충 요법을 했지만, 혈청 안드로겐 수치는 정상보다 낮았다. 환자의 성호르몬 불균형 상태가 류마티스 관절염의 발병과 경과에 영향을 미쳤을 것으로 추정된다. Klinefelter`s syndrome is a disorder of sexual differentiation in males, characterized by the presence of two or more X-chromosomes, hypogonadism, and lack of secondary sexual characteristics. The association between Klinefelter`s syndrome and systemic lupus erythematous has been described, while cases of rheumatoid arthritis associated with Klinefelter`s syndrome are rare. We report the first Korean case: a 29-year-old man with Klinefelter`s syndrome who developed rheumatoid arthritis. The sex hormone imbalance might have influenced the onset and course of his disease. (Korean J Med 2011;81:412-415)
Comparison of Indomethacin, Diclofenac and Aspirin-Induced Gastric Damage according to Age in Rats
Seo, Pyoung Ju,Kim, Nayoung,Kim, Joo-Hyon,Lee, Byoung Hwan,Nam, Ryoung Hee,Lee, Hye Seung,Park, Ji Hyun,Lee, Mi Kyoung,Chang, Hyun,Jung, Hyun Chae,Song, In Sung The Korean Society of Gastroenterology; the Korean 2012 Gut and Liver Vol.6 No.2
<P><B>Background/Aims</B></P><P>Aging gastric mucosa is known to have decreased mucosal defenses and increased susceptibility to injury by nonsteroidal anti-inflammatory drugs. Depending on the type of nonsteroidal anti-inflammatory drug (NSAID), the underlying mechanisms and the extent of damage to the stomach or intestine may differ. This study was performed to evaluate the acute gastric damage caused by different doses of indomethacin, diclofenac and aspirin in rats of various ages.</P><P><B>Methods</B></P><P>For the acute models, indomethacin (10, 20 or 40 mg/kg), diclofenac (40 or 80 mg/kg) or aspirin (100 mg/kg) was given to 7- and 25-week-old and 1-year-old Sprague-Dawley rats by intragastric gavage. The gross ulcer index, damage area as assessed by imaging, histological index, myeloperoxidase (MPO) activity, and cytosolic phospholipase A<SUB>2</SUB> (cPLA<SUB>2</SUB>) levels were measured after 24 hours.</P><P><B>Results</B></P><P>The gross ulcer index and damage area increased with age in the presence of three NSAIDs (p<0.05). The increases in MPO levels induced by diclofenac and aspirin were significantly higher in 1-year-old than 7-week-old rats (p<0.05). cPLA<SUB>2</SUB> expression induced by indomethacin (10 and 40 mg/kg) was greater in the 1-year-old rats, compared with 7-week-old rats (p<0.05).</P><P><B>Conclusions</B></P><P>NSAID-induced acute gastric damage increased in a dose- and age-dependent manner.</P>