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황기아,백미나 한국가정과학회 2004 한국가정과학회지 Vol.7 No.1
This study examined one room(studio apartment) residential deweller's housing behavior and housing need, and the relationship between the sense of housing values and housing satisfaction of one-room residence, The study surveyed 302 one-room residents in Busan city. The researcher modified, complimented, and used the previous researches on housing values and housing satisfaction. The analysis of the data used SPSS Win 10.0 program. The results of the research can be summarized as follows: 1. The motive of choosing one-room residence was mainly the closeness to the school or work, Jeonse(Rent with a one-room deposit) was more common than ownership, and the size is one-room residence was 10 to 15 Pyeong. 2. Among the five housing values of one-room residence dwellers, that is, amenity, indoor and outdoor environment, economy/convenience, convenience in transportation, and the interior functionality, the convenience in transportation was ranked highest, and the indoor and out door environment and economy/convenience followed. 3. The housing satisfaction of one-room residents was highest in location, and also high in the safety and the security or privacy, and the convenience of inside facility.
황기아,백미나 東亞大學校 附設 生活科學硏究所 2002 생활과학연구 논문집 Vol.10 No.-
This study examined one-room(studio apartment) residential dweller's housing values and housing satisfaction, and the relationship between the sense of housing values and housing satisfaction of one-room residence. The study surveyed 302 one-room residents in Busan city, The researcher modified, complimented, and used the previous researches on housing values and housing satisfaction. The analysis of the data used SPSS Win 10.0 program. The results of the research can be summarized as follows: 1. The motive of choosing one-room residence was mainly the closeness to the school or work, Jeonse(Rent with a one-room deposit) was more common than ownership, and the size of one-room residence was 10 to 15 Pyeong. 2. Among the five housing values of one-room residence dwellers, that is, amenity, indoor and outdoor environment, economy/convenience, convenience in transportation, and the interior functionality, the convenience in transportation was ranked highest, and the indoor and out door environment and economy/convenience were followed. 3. The housing satisfaction of one-room residents was highest in location, and also high in the safety and the security or privacy, and the convenience of inside facility.
정현아,윤지영,황재선,주나미 한국식생활문화학회 2004 韓國食生活文化學會誌 Vol.19 No.2
The purpose of this study was to determine the organoleptic characterisitcs of cauliflower pickles made in various compounding ratio according to central conposite design for optimum organoleptic characteristics of the cauliflower pickles. The optimum mixing condition of cauliflower pickles were optimized, using central composite design with 3 variables and 3 levels, by response surface methodology. The various kinds of cauliflower pickle were made in various compounding ratio of vinegar, salt and sucrose - critical ingredients of pickle recipe - and were presented to reliable panels, who graded the subjects in 7 degrees for 4 items : color, lavor, hardness and overall quality. The optimum mixing conditions of cauliflower pickle were 603.50g of vinegar, 80.13g of salt and 251.079 of sucrose in the maximum point of overall quality.
李年純,朴惠羅,羅美香 영남대학교 자원문제연구소 1991 資源問題硏究 Vol.10 No.-
In order to investgate the change of dye adsorption and printing effect by alkali concentration steaming time, and dyeing paste, cotton fabric was printed with the reactive dyes. The results are as follows : 1. The most effect of dye adsorption showed at 0.5% Na2CO₃to dyeing paste for C. I. Reactive Blue28 and 1% Na2CO₃for Blue 198. 2. The effect of dye adsorption was practically unchanged according to the increase of steaming time for printing was 10 min. 3. The most effect of printing showed at 3% paste to dyeing paste. 4. The colorfastness to laundering of each dye was excellent and the lightfastness was good, but the colorfastness to perspiration was poor more or less. 5. It was found that the colorfastness was not influenced by alkali concentration and steaming time.
( Hyun Ju Lee ),( Ja Sung Rho ),( Shao Ran Gui ),( Mi Kyung Kim ),( Yu Kyoung Lee ),( Yeon Sook Lee ),( Jeong Eun Kim ),( Eu Na Cho ),( Mong Cho ),( Tae Ho Hwang ) 대한간학회 2011 Clinical and Molecular Hepatology(대한간학회지) Vol.17 No.3
Background/Aims: JX-594 is an oncolytic virus derived from the Wyeth vaccinia strain that causes replication-dependent cytolysis and antitumor immunity. Starting with a cross-examination of clinical-trial samples from advanced hepatocellular carcinoma patients having high levels of aldosterone and virus amplification in JX-594 treatment, we investigated the association between virus amplification and aldosterone in human cancer cell lines. Methods: Cell proliferation was determined by a cell-counting-kit-based colorimetric assay, and vaccinia virus quantitation was performed by quantitative polymerase chain reaction (qPCR) and a viral plaque assay. Also, the intracellular pH was measured using a pH-sensitive dye. Results: Simultaneous treatment with JX-594 and aldosterone significantly increased viral replication in A2780, PC-3, and HepG2 cell lines, but not in U2OS cell lines. Furthermore, the aldosterone treatment time altered the JX-594 replication according to the cell line. The JX-594 replication peaked after 48 and 24 hours of treatment in PC-3 and HepG2 cells, respectively. qPCR showed that JX-594 entry across the plasma membrane was increased, however, the changes are not significant by the treatment. This was inhibited by treatment with spironolactone (an aldosterone-receptor inhibitor). JX-594 entry was significantly decreased by treatment with EIPA [5-(N-ethyl-N-isopropyl)amiloride; a Na+/H+-exchange inhibitor], but aldosterone significantly restored JX-594 entry even in the presence of EIPA. Intracellular alkalization was observed after aldosterone treatment but was acidified by EIPA treatment. Conclusions: Aldosterone stimulates JX-594 amplification via increased virus entry by affecting the H+ gradient. (Korean J Hepatol 2011;17:213-219)
황나미 ( Na-mi Hwang ) 한국보건사회연구원 1994 保健社會硏究 Vol.14 No.1
산모나 태아에게 심각한 위험이 미칠때 시행되는 제왕절개분만은 임산부사망률과 주산기사망률 감소에 기여한 것은 사실이나 최근 계속적인 증가를 보이고 있는 경향에 대해서는 양질의료의 추구와 국민의료비 억제측면에서 간과할 수 없는 문제이다. 이에 적정수준의 분만서비스를 제공할 수 있는 공급기반을 모색하고, 더 나아가서는 의료서비스 적정화를 위한 전략개발의 기반을 구축하기 위하여 적응증에 관한 임상적 고찰과 더불어 전국 종합병원을 대상으로 제 특성별 제왕절개분만 관련요인을 분석하였다. 연구결과, 평균 제왕절개분만율은 32.8%이며, 제왕절개분만율에 영향을 미치는 종합병원 특성을 소재지역, 분만건수, 설립주체로 나타나, 종합병원이 적정한 분만서비스를 제공하도록 하기 위해서는 의료인에게 자발적으로 질식분만을 권장하도록 유도하는 방안과 현행 의료보험 분만수가의 수정 및 보완이 그 대응방안으로 제시되었다. One of the most important issues facing health services is the rapidly increasing rate of cesarean section delivery. The Korean cesarean section rate has increased from 9.6 % in 1986 to approximately 28% in 1993 according to healthinsurance claim bills which have been submitted to National Federation of Medical Insurance. The charges for cesarean section are as much as four times those for vaginal births. The purpose of this study was to estimate the cesarean section rate by characteristics of General Hospital and analyze influencing factors at General Hospital on cesarean section rate for the adequate delivery services. The data was obtained from 1992 birth statistics of each General Hospital. Study population included all General Hospitals in Korea with a delivery service, 217 General Hospitals. The results are as follws : - Out of all deliveries of 275, 076, hospitalspecific cesarean section rates varied 0.01 % to 91.7 % and the mean of cesarean section rate of General Hospital was 32.8 %. - Several characteristics of General Hospital are stongly associated with cesarean section rate, such as location that is geographical region, ownership and deliveries per year. Cesarean section rate was negatively associated with deliveries per year and lower deliveries per year appear to have a higher cesarean section rate. General Hospitals established by private foundations or proprietary appear to have a higher cesarean section rate than public or teaching hospitals. It is concluded that the increase of cesarean section rate has been influenced by the health insurance system. It implies that high cesarean section rate is related to the financial incentives of cesarean section in comparison with vaginal delivery. I suggest a combined strategy may be necessary to lower the unjustifiably high cesarean section rate. One, doctors should obtain the second opinion and the other is minimizing financial incentives of cesarean section.
Ka, Na-Lee,Na, Tae-Young,Na, Hyelin,Lee, Min-Ho,Park, Han-Su,Hwang, Sewon,Kim, Il Yong,Seong, Je Kyung,Lee, Mi-Ock American Association for Cancer Research 2017 Cancer Research Vol.77 No.9
<P>These findings show how a nuclear receptor and its ligands blunts repair of double-strand DNA breaks, suggesting their candidacy as therapeutic targets in cancer patients.</P><P>DNA repair capacity is critical for survival of cancer cells upon therapeutic DNA damage and thus is an important determinant of susceptibility to chemotherapy in cancer patients. In this study, we identified a novel function of nuclear receptor NR1D1 in DNA repair, which enhanced chemosensitivity in breast cancer cells. NR1D1 inhibited both nonhomologous end joining and homologous recombination double-strand breaks repair, and delayed the clearance of γH2AX DNA repair foci that formed after treatment of doxorubicin. PARylation of NR1D1 by PARP1 drove its recruitment to damaged DNA lesions. Deletion of the ligand binding domain of NR1D1 that interacted with PARP1, or treatment of 6-(5H)-phenanthridinone, an inhibitor of PARP1, suppressed the recruitment of NR1D1 to DNA damaged sites, indicating PARylation as a critical step for the NR1D1 recruitment. NR1D1 inhibited recruitment of the components of DNA damage response complex such as SIRT6, pNBS1, and BRCA1 to DNA lesions. Downregulation of NR1D1 in MCF7 cells resulted in resistance to doxorubicin, both <I>in vitro</I> and <I>in vivo</I>. Analysis of four public patient data sets indicated that NR1D1 expression correlates positively with clinical outcome in breast cancer patients who received chemotherapy. Our findings suggest that NR1D1 and its ligands provide therapeutic options that could enhance the outcomes of chemotherapy in breast cancer patients. <I>Cancer Res; 77(9); 2453–63. ©2017 AACR</I>.</P>
Visual Control of Automated COVID-19 Swab Sampling Robot
Guebin Hwang(황규빈),Jongwoon Lee(이종원),Sungwook Yang(양성욱) 대한기계학회 2021 대한기계학회 춘추학술대회 Vol.2021 No.11
As coronavirus disease 2019 (COVID-19) has become a global pandemic, the initial screening of patients is regarded as the most effective way to prevent the spread of COVID-19. However, enormous swap sampling has led to the high workload of medical professionals as the number of infection has increased. Therefore, we propose a swab sampling robot systems in a fully automated fashion to address these issues. For automation of nasopharyngeal swab, the proposed robot system is designed to automatically insert a sampling swab through one nostril and collect sample via visual feedback. A prototype of the robot system incorporates a 6-DOF manipulator and a RGB-D sensor to investigate the feasibility of a visual-servo control scheme in automatic swab sampling. For accurate and safe operation, a deep learning-based nostril detection algorithm is adopted, which offers an accuracy of 99% at 60 FPS. Given the nostril position in 3D, the robot is planned to reach the target within a specific time. Since the kinematic control of the robot is prone to failure in reaching the target, we introduce the visual-servo control of the robot via the detection and tracking of error between the target position and the current swab tip. As a result, the visual-servo controlled robot could successfully reach the nostril target within an error of 1.11 mm on average for 30 trails trials different swabs, while the non-visual control with a 10.58-mm positioning error failed to reach the target.