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Modeling of wind-induced fatigue of cold-formed steel sheet panels
Rosario-Galanes, Osvaldo,Godoy, Luis A. Techno-Press 2014 Structural Engineering and Mechanics, An Int'l Jou Vol.49 No.2
Wind-induced failure around screwed connections has been documented in roof and wall cladding systems made with steel sheet cold-formed panels during high wind events. Previous research has found that low cycle fatigue caused by stress concentration and fluctuating wind loads is responsible for most such failures. A dynamic load protocol was employed in this work to represent fatigue under wind effects. A finite element model and fatigue criteria were implemented and compared with laboratory experiments in order to predict the fatigue failure associated with fluctuating wind loads. Results are used to develop an analytical model which can be employed for the fatigue analysis of steel cold-formed cladding systems. Existing three dimensional fatigue criteria are implemented and correlated with fatigue damage observed on steel claddings. Parametric studies are used to formulate suitable yet simple fatigue criteria. Fatigue failure is predicted in different configurations of loads, types of connections, and thicknesses of steel folded plate cladding. The analytical model, which correlated with experimental results reported in a companion paper, was validated for the fatigue life prediction and failure mechanism of different connection types and thicknesses of cold-formed steel cladding.
Modeling of wind-induced fatigue of cold-formed steel sheet panels
Osvaldo Rosario-Galanes,Luis A. Godoy 국제구조공학회 2014 Structural Engineering and Mechanics, An Int'l Jou Vol.49 No.2
Wind-induced failure around screwed connections has been documented in roof and wall cladding systems made with steel sheet cold-formed panels during high wind events. Previous research has found that low cycle fatigue caused by stress concentration and fluctuating wind loads is responsible for most such failures. A dynamic load protocol was employed in this work to represent fatigue under wind effects. A finite element model and fatigue criteria were implemented and compared with laboratory experiments in order to predict the fatigue failure associated with fluctuating wind loads. Results are used to develop an analytical model which can be employed for the fatigue analysis of steel cold-formed cladding systems. Existing three dimensional fatigue criteria are implemented and correlated with fatigue damage observed on steel claddings. Parametric studies are used to formulate suitable yet simple fatigue criteria. Fatigue failure is predicted in different configurations of loads, types of connections, and thicknesses of steel folded plate cladding. The analytical model, which correlated with experimental results reported in acompanion paper, was validated for the fatigue life prediction and failure mechanism of different connection types and thicknesses of cold-formed steel cladding.
Hypocholesterolemia in Patients with an Amebic Liver Abscess
( Maria S Flores ),( Adriana Obregon Cardenas ),( Eva Tamez ),( Elba Rodriguez ),( Katiushka Arevalo ),( Isela Quintero ),( Rolando Tijerina ),( Francisco Bosques ),( Luis Galan ) 대한소화기학회 2014 Gut and Liver Vol.8 No.4
Background/Aims: Many parasites induce changes in the lipid profiles of the host. Cholesterol increases the virulence of Entamoeba histolytica in animal models and in vitro culture. This study aimed to determine, in patients with an amebic liver abscess, the correlation between cholesterol and other features, such as the size and number of abscesses, standard hematological and serum chemistry profiles, liver tests, and duration of hospital stay. Methods: A total of 108 patients with an amebic liver abscess and 140 clinically healthy volunteers were investigated. Cholesterol and triglycerides were measured in the sera. The data from medical observations and laboratory tests were obtained from the clinical records. Results: A total of 93% of patients with an amebic liver abscess showed hypocholesterolemia not related to any of the studied parameters. Liver function tests correlated with the size of the abscess. The most severe cases of amebic liver disease or death were found in patients whose cholesterol levels continued to decrease despite receiving antiamebic treatment and hospital care. Conclusions: Our results show that the hypocholesterolemia observed in patients with an amebic liver abscess is not related to any of the clinical and laboratory features analyzed. This is the first study relating hypocholesterolemia to severity of hepatic amebiasis. (Gut Liver 2014;8:415-420)