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      • SCOPUSKCI등재

        Effects of Aqueous Extract of Schizandra Chinensis Fruit on Cadmium-Induced Change of Monoamine Neurotransmitters in Rats

        Zhao, Zheng Lin,Zhao, Guang Wen,Li, Li,Li, Meng Quan,Guan, Li Xin,Yang, Xu Dong,Li, Hou Zhong,Lin, Feng,Lee, Jong-Rok,Zhao, Rong Jie Korean Society of ToxicologyKorea Environmental Mu 2009 Toxicological Research Vol.26 No.1

        The effects of aqueous extract of Schizandra Chinensis Fruit (AESC) on cadmium-induced changes of monoamine neurotransmitters in the different brain regions of adult rats were investigated. Male rats were received intraperitoneal (i.p.) administration of CdCl2 (0.6 mg/kg/d) for 21 days and sacrificed 7 days after the last administration. Concentrations of norepinephrine (NE), dopamine (DA) in striatum and serotonin (5-HT), 5-hydroxyindole acetic acid (5-HIAA) in cortex were measured by HPLC. There were significant decreases of NE, DA, 5-HT and 5-HIAA in Cd intoxicated rats (P < 0.05), while pretreatment with AESC (20 mg/kg/d or 60 mg/kg/d, p.o., 30 min before $CdCl_2$) greatly inhibited the decrease of monoamine transmitters, respectively (P < 0.05). Also, AESC significantly increased the reduction of glutathione contents and superoxide dismutase activities in cortex induced by $CdCl_2$. These results suggest that AESC ameliorates Cd-induced depletion of monoamine neurotransmitters in brain through its antioxidant activity.

      • KCI등재

        Effects of Aqueous Extract of Schizandrae Fructus on Lead-Induced Change of Monoamine Neurotransmitters in Hippocampus

        Zhao, Rong Jie,Zhao, Zheng Lin,Zhao, Xiu Feng,Zhao, Guang Wen,Li, Meng Quan,Wu, Yi Yan,Li, Jing Qiu,Guan, Li Xin,Kim, Sang-Chan The Korean Medicine Society for the Herbal Formula 2009 大韓韓醫學方劑學會誌 Vol.17 No.2

        The effects of aqueous extract of Schizandrae Fructus (AESC) on lead (Pb)-induced changes of monoamine neurotransmitters in the hippocampus (HIP) of adult rats were investigated. Male Sprague-Dawley rats were received intraperitoneal (i.p.) administration of Pb acetate (5 mg/kg/d) for 28 days and sacrificed 7 days after the last administration. Concentrations of norepinephrine (NE), dopamine (DA), serotonin (5-HT), 5-hydroxyindole acetic acid (5-HIAA) in HIP were measured by HPLC. There were significant decreases of NE, DA, 5-HT and 5-HIAA in Pb treated rats (P < 0.05), while pretreatment with AESC (100 mg/kg/d or 300 mg/kg/d, p.o., 2 h before Pb) greatly inhibited the decrease of monoamine transmitters, respectively (P < 0.05). Also, AESC (300 mg/kg/d) significantly increased the reduction of glutathione contents and superoxide dismutase activities in HIP induced by chronic Pb. These results suggest that AESC ameliorates Pb-induced depletion of monoamine neurotransmitters in HIP through its antioxidant activity.

      • KCI등재

        Effects of Aqueous Extract of Schizandra Chinensis Fruit on Cadmium-Induced Change of Monoamine Neurotransmitters in Rats

        Zheng Lin Zhao,Guang Wen Zhao,Li Li,Meng Quan Li,Li Xin Guan,Xu Dong Yang,Hou Zhong Li,Feng Lin,Jong Rok Lee,Rong Jie Zhao 한국독성학회 2009 Toxicological Research Vol.25 No.1

        The effects of aqueous extract of Schizandra Chinensis Fruit (AESC) on cadmium-induced changes of monoamine neurotransmitters in the different brain regions of adult rats were investigated. Male rats were received intraperitoneal (i.p.) administration of CdCl₂ (0.6 ㎎/㎏/d) for 21 days and sacrificed 7 days after the last administration. Concentrations of norepinephrine (NE), dopamine (DA) in striatum and serotonin (5-HT), 5-hydroxyindole acetic acid (5-HIAA) in cortex were measured by HPLC. There were significant decreases of NE, DA, 5-HT and 5-HIAA in Cd intoxicated rats (P < 0.05), while pretreatment with AESC (20 ㎎/㎏/d or 60 mg/kg/d, p.o., 30 min before CdCl₂) greatly inhibited the decrease of monoamine transmitters, respectively (P < 0.05). Also, AESC significantly increased the reduction of glutathione contents and superoxide dismutase activities in cortex induced by CdCl₂. These results suggest that AESC ameliorates Cd-induced depletion of monoamine neurotransmitters in brain through its antioxidant activity.

      • KCI등재

        Effects of Acupuncture at Zu-San-Li (ST36) on the Activity of the HypothalamicePituitaryeAdrenal Axis during Ethanol Withdrawal in Rats

        Zheng Lin Zhao,Bong Hyo Lee,Feng Lin,YanQin Guo,Yi Yan Wu,Sang Mi Park,Sunghyeon In,Sang Chan Kim,Chae Ha Yang,Rong Jie Zhao 사단법인약침학회 2014 Journal of Acupuncture & Meridian Studies Vol.7 No.5

        The current study investigated the effects of acupuncture at Zu-San-Li (ST36) on the hypothalamicepituitaryeadrenalaxis during ethanol withdrawal in rats. Rats were intraperitoneallytreated with 3 g/kg/day of ethanol or saline for 28 days. Following 24 hours ofethanol withdrawal, acupuncture was applied at bilateral ST36 points or non-acupoints(tail) for 1 minute. Plasma levels of corticosterone (CORT) and adrenocorticotropic hormone(ACTH) were measured by radioimmunoassay (RIA), and the corticotropin-releasingfactor (CRF) protein levels in the paraventricular nucleus of the hypothalamus were alsoexamined by RIA 20 minutes after the acupuncture treatment. RIA showed significantlyincreased plasma levels of CORT and ACTH in the ethanol-withdrawn rats compared withthe saline-treated rats, which were inhibited significantly by the acupuncture at the acupointST36 but not at the non-acupoint. Additionally, ethanol withdrawal promoted CRFprotein expressions in the paraventricular nucleus of the hypothalamus, which were alsoblocked by the acupuncture at ST36. These findings suggest that acupuncture at the specific acupoint ST36 can inhibit ethanol withdrawal-induced hyperactivation of hypothalamicepituitaryeadrenalaxis, and it may be mediated via the modulation of hypothalamicCRF.

      • KCI등재

        国家形象视域下 《琅琊榜》 的跨国传播学研究

        ?林林(Zhao, Lin-Lin),王?霞(Wang, Bao-Xia) 한국중어중문학회 2017 中語中文學 Vol.- No.70

        The paper which is based on the basic theory of international communication study under the perspective of national image, comprehensively and specifically analyzed the hit Chinese TV series Nirvana in Fire from the three aspects of communication contents, communication symbols and communication effect to summarize the reasons for the success of the international communication of the TV series First, the theme of the TV series delivers a lot of global common value which is helpful to implement localization and arouse the sympathetic response of local viewers .The Chinese story Nirvana in Fire tells the pursuit of the contemporary global common value. With the theme of utter innocence, the series celebrates the loyalty to love,presents a profound friendship and shows the pursuit of the ideal society which is the whole world as a one community. For the global viewers, it is kind of placebo under the background of the modernization. Second, the plot of the TV series is full of decryption and reasoning which satisfied the curiosity of the global viewers about unknown and the demand for upholding the justice. The TV series Nirvana in Fire presents difficult problems and secrets one by one which could make the viewers find the truth in the chaos of emotional entanglements and conflicts of interest to experience pleasure. Third,thecommunicationsymbolsarefulloforiental charm which provide the viewers an opportunity to enjoy different cultures. The processing of the pictures and colors presents the traditional Chinese ink-wash painting style to bring the viewers into a traditional Chinese world which is full of classic beauty. Every motion of all actors in the series shows aesthetic perception of the state of ceremonies. The application of chivalry elements makes the series an eastern fairy tale world. Forth,the applicationofnetworknewmediaincreasethespeedanddepth of the spread. Nirvana in Fire spread to the countries and regions without broadcasting through video website s and fansub websites. In addition, the series created topics of discussion on the social network to improve the effect of spread.

      • Geographic Distribution and Epidemiology of Lung Cancer During 2011 in Zhejiang Province of China

        Lin, Xia-Lu,Chen, Yan,Gong, Wei-Wei,Wu, Zhao-Fan,Zou, Bao-Bo,Zhao, Jin-Shun,Gu, Hua,Jiang, Jian-Min Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.13

        Background: To explore etiology for providing scientific clues for the prevention of lung cancer. Materials and Methods: Data for lung cancer incidence and meteorological geographic factors from 25 counties in Zhejiang province of China during 2011 were studied. Stepwise multiple regression and correlation analysis were performed to analyze the geographic distribution and epidemiology of lung cancer. Results: 8,291 new cases (5,998 in males and 2,293 females) of lung cancer during 2011 in Zhejiang province were reported in the 25 studied counties. Reported and standardized incidence rates for lung cancer were 58.0 and 47.0 per 100,000 population, respectively. The incidence of lung cancer increased with age. Geographic distribution analysis shows that the standardized incidence rates of lung cancer in northeastern Zhejiang province were higher than in the southwestern part, such as in Nanhu, Fuyang, Wuxing and Yuyao counties, where the rates were more than 50 per 100,000 population. In the southwestern Zhejiang province, for instance, in Yueqing, Xianju and Jiande counties, the standardized incidence rates of lung cancer were lower than 37 per 100,000 population. Spearman correlation tests showed that forest coverage rate, air quality index (AQI), and annual precipitation level are associated with the incidence of lung cancer. Conclusions: Lung cancer in Zhejiang province shows obvious regional differences. High incidence appears associated with low forest coverage rate, poor air quality and low annual precipitation. Therefore, increasing the forest coverage rate and controlling air pollution may play an important role in lung cancer prevention.

      • KCI등재
      • KCI등재

        Efficient algorithm for finding the inverse and the groupinverse of FLS $r$-circulant matrix

        Zhao-Lin Jiang,Zong-Ben Xu 한국전산응용수학회 2005 Journal of applied mathematics & informatics Vol.18 No.1-2

        An efficient algorithm for finding the inverse and the group inverse of the FLS r-circulant matrix is presented by Euclidean algorithm. Extension is made to compute the inverse of the FLS r-retrocirculant matrix by using the relationship between an FLS r-circulant matrix and an FLS r-retrocirculant matrix. Finally, some examples are given.

      • Association between Dietary Behavior and Esophageal Squamous Cell Carcinoma in Yanting

        Zhao, Lin,Liu, Chun-Ling,Song, Qing-Kun,Deng, Ying-Mei,Qu, Chen-Xu,Li, Jun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

        Background: Yanting is one of high risk areas for esophageal cancer and the screening program was therefore initiated there. This study was aimed to investigate the dietary behaviors on the risk of esophageal squamous cell carcinoma (ESCC), among the individuals with normal and abnormal esophagus mucosa. Materials and Methods: A frequency matched case-controls study was proposed to estimate the different distribution of dietary behavior between individuals of control, esophagitis and cancer groups. Cancer cases were selected from hospitals. Esophagitis cases and controls were selected from screening population for ESCC. Health workers collected data for 1 year prior to interview, in terms of length of finishing a meal, temperature of eaten food and interval between water boiling and drinking. Chi-square, Kruskal-Wallis tests and unconditional logistic regression model were used to estimate differences and associations between groups. Results: Compared with controls, length of finishing a meal ${\geq}15mins$ was related to a reduced OR for cancer (OR=0.46, 95%CI, 0.22-0.97) and even compared with cases of esophagitis, the OR of cancer was reduced to 0.30 (95%CI, 0.13-0.72). The OR for often eating food at a high temperature was 2.48 (95%CI 1.06, 5.82) for ESCC as compared with controls. Interval between water boiling and drinking of ${\geq}10mins$ was associated with lower risk of cancer: the OR was 0.18 compared with controls and 0.49 with esophagitis cases (p<0.05). Conclusions: Length of eating food ${\geq}15mins$ and interval between water boiling and drinking ${\geq}10mins$ are potentially related to reduced risk of esophageal SCC, compared with individuals with normal and abnormal esophageal mucosa. Recommendations to Yanting residents to change their dietary behaviors should be made in order to reduce cancer risk.

      • KCI등재

        Aerodynamic and aero-elastic performances of super-large cooling towers

        Lin Zhao,Xu Chen,Shitang Ke,Yaojun Ge 한국풍공학회 2014 Wind and Structures, An International Journal (WAS Vol.19 No.4

        Hyperbolic thin-shell cooling towers have complicated vibration modes, and are very sensitive to the effects of group towers and wind-induced vibrations. Traditional aero-elastic models of cooling towers are usually designed based on the method of stiffness simulation by continuous medium thin shell materials. However, the method has some shortages in actual engineering applications, so the so-called “equivalent beam-net design method” of aero-elastic models of cooling towers is proposed in the paper and an aero-elastic model with a proportion of 1: 200 based on the method above with integrated pressure measurements and vibration measurements has been designed and carried out in TJ-3 wind tunnel of Tongji university. According to the wind tunnel test, this paper discusses the impacts of self-excited force effect on the surface wind pressure of a large-scale cooling tower and the results show that the impact of self-excited force on the distribution characteristics of average surface wind pressure is very small, but the impact on the form of distribution and numerical value of fluctuating wind pressure is relatively large. Combing with the Complete Quadratic Combination method (hereafter referred to as CQC method), the paper further studies the numerical sizes and distribution characteristics of background components, resonant components, cross-term components and total fluctuating wind-induced vibration responses of some typical nodes which indicate that the resonance response is dominant in the fluctuating wind-induced vibration response and cross-term components are not negligible for wind-induced vibration responses of super-large cooling towers.

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