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      • 대구지방의 위암에 대한 병리조직학적 연구

        홍석재,이태숙,최원희,이경철 영남대학교 의과대학 1985 Yeungnam University Journal of Medicine Vol.2 No.1

        대구지방의 위암에 대한 병리조직학적 연구의 목적으로 대구 일원의 의료기관에서 수집한 위내시경 표본과 위절제수술 표본에 의해 위암으로 확진된 350예 및 130예의 조직학적 유형과 연령 분포는 다음과 같다. 1. 위내시경 표본 350예 중 선암이 344예(98.3%)로서 대부분을 차지하였으며 편평상피암과 미분화암은 불과 6예(1.7%) 뿐이었다. 선암 중에서는 tubular type가 215예(61.4%)로서 가장 많았고, 다음이 signet-ring cell type으로 92예(26.3%)이었다. 연령 분포는 50세대가 가장 많이 발생하여 120예(34.3%), 다음이 60세대로 81예(23.1%), 40세대가 76예(21.7%), 70세대가 33예(9.4%), 30세대가 32예(9.1%), 20세대가 8예(2.3%) 등의 순위였다. 2. 위절제수술 표본 130예중 가장 많은 조직학적 유형은 역시 선암으로 127예(97.7%)였고, 만성소화성 위궤양에서 발생한 것이 3예 있었다. 선암 중에서는 tubular type이 86예(66.2%)로 제일 많았고 다음이 signet-ring cell type였다. 연령분포는 50세대에서 50예(38.5%)로 가장 많이 발생하였고, 다음 60세대가 36예(17.7%), 40세대가 21예(16.2%), 30세대가 11예(8.5%), 70세대가 6예(4.6%), 그리고 10세대에서 1예(0.8%)있었다. For evaluation on the histopathologic studies, and age sex distribution of the gastric carcinomas in the Taegu Area, the gastrectomized and gastoroscopic biopsy materials were collected at the Department of Pathology, College of Medicine, Yeungnam University, and the analyzed results were as follows: 1. In total of 350 cases of gastroscopic biopsy materials adenocarcinomas are 344 cases (98.3%), squamous cell carcinomas and undifferentiated carcinomas are only 6 cases (1.7%). In adenocarcinomas the most of all are tubular type, 215 cases(61.4%). In age distribution the highest is the 50th age group, and 120 cases (34.3%), the next, 60th, 81 cases (23.1%), 40th, 76 cases (21.7%), respectively. 2. In total of 130 cases of gastrectomized materials adenocarcinomas are 127 cases (97.7%), and are the highest incidence, the next, carcinomas originated from chronic peptic ulcer of the stomach, and are 3 cases (2.3%). In adenocarcinomas the highest are tubular type, 86 cases (66.2%), the next, signet-ring cell type, 20 cases (15.4%). The highest age incidence of the age group is 50th, and the next, 60th, 40th, 30th, 70th and 10th age group, respectively.

      • KCI등재

        우리나라 주택의 외관형태의 다양성에 관한 연구 : 1980년대 이후 건축가가 설계한 주택을 중심으로

        홍숙경,한기정,손세관 대한건축학회 2004 대한건축학회논문집 Vol.20 No.5

        The purposes of this study are to analyse the varieties of external shapes of detached houses in Korea after 1980s and to arrange the characteristics of those. For these purposes, 152 houses designed by architects have been selected. And the general form, the relationship of external form factors, the intermediate spaces in each form, the arrangement of internal spaces, especially livingroom and master bed room, and the roof styles of those were analysed by typological method. The results of analysis are as follows; Firstly, the general form of houses in Korea after 1980s is ㄱ-shape. Secondly, the external forms of houses are composed with complex form factors, and these form factors are annexed, adjoined, and crossed at right angles. Thirdly, the separated form factors are connected with hallway or staircase. Fourthly, the arrangement of a living room and a master bed room are identified by adjoined each other on the first floor. Fifthly, the representative roof style of architect-designed houses in Korea is even roof.

      • KCI등재

        여성용 춘추복지의 태에 관한 연구 (제1보) : 태의 주관적 평가척도 개발을 중심으로 Development for the Subjective Hand Evaluation Scale

        홍경희,김재숙,박춘순,박길순,이영선,김재임 한국의류학회 1994 한국의류학회지 Vol.18 No.3

        KES-F system is widely used in hand evaluation, however, it has encountered some challenges, such as the overlapping of primary hand value, lack of predictability in case of women's thin dress, difficulties in communication due to complexity of primary hand expression and cultural differences in subjective evaluation. Therefore, this study was intended 1) to find out the Korean primary hand expressions (factors) of the overall concept of fabric hand associated with women's spring-fall dress fabrics, 2) to develope the fabric hand attributes of those fabrics and 3) to show whether there are any differences between Korean textile experts and non-experts in terms of the concept of fabric hand descriptors of hand attributes. Data base of hand descriptors were collected by extensive interview 60 experts and 10 non-experts using 110 spring-fall dress fabrics. Finally, hand of selected fabrics was assessed by 205 experts and 265 non-experts using 7-point scale of 26 descriptors based on the data base. Subjective ratings were analyzed by common factor analysis with varimax rotation. It was found that Korean primary hand expression indicated rather simple property, hence, did not equate exactly with Japanese experssion(e.g. koshi, shinayakasa, etc.) which contains several material properties. There were differences in stretch & resilience, especially liveliness, between the judgement of non-expert than to experts. Surface-related category was more important to non-experts than to experts. Slight differences were found between both groups in terms of preferred descriptors. Important descriptors as a rating scale were suggested.

      • KCI등재후보
      • RAPD 표지자 분석에 의한 가시아메바속 한국분리주의 유전적 지위

        홍용표,오승환,라미숙,임경일 INSTITUTE OF TROPICAL MEDICINE YONSEI UNIVERSITY 1995 YONSEI REPORTS ON TROPICAL MEDICINE Vol.26 No.1

        가시아메바 속(Acanthamoeba spp.)의 DNA 염기 구성 정보와 관계없이 임의의 10개의 염기로 구성된 프라이머를 사용하여 random amplified polymorphic DNA-polymerase chain reaction(RAPD-PCR)에 의해 게놈 상의 DNA를 무작위로 증폭하여 확인된 표지자로써 한국 분리주 및 외국 분리주와 기존의 알려진 4개 가시아메바 종간의 유전적 근연관계 분석을 통해서 4개 한국분리주의 분류상의 성상을 규명하였다. 본 연구에서 A. culbertsoni, A. hatchetti, A. triangularis, A. polyphaga와 한국 분리주인 YM-2, YM-3, YM-4, YM-5, 그리고 외국 분리주인 HOV의 게놈 DNA는 18종류의 프라이머에 의하여 다양한 양상의 증폭산물을 보였으며, 그 중 9개 프라이머는 한국 분리주간에도 특이성을 보이는 RAPD 표지자를 제공하였다. 총 18개의 프라이머에 대한 증폭산물을 대상으로 각 시료의 유사도를 조사한 결과, A. culbertsoni는 A. hatchetti, A. triangularis, A. polyphaga와 유사도가 각각 0.300, 0.308, 0.313이었고, A. hatchetti와 A. triangularis간의 유사도는 0.838이었다. 한국 분리주 YM-2, -3, -4간의 평균 유사도는 0.959이었고, YM-2, -3, -4와 A. hatchetti, A. triangularis간의 평균 유사도는 0.832이었다. 한국 분리주 YM-5는 YM-2, -3, -4 간의 비교에서 평균 0.237의 유사도를 보인 반면, A. culbertsoni와 유사도 0.857을 보여, 다른 한국 분리주보다 A. culbertsoni와 유전적으로 유사함을 알 수 있었다. UPGMA법에 의한 유전적 근연관계 분석 결과 phenogram 상에 두개의 분지군이 존재하는데, A. hatchetti, A. triangularis 및 3개 한국 분리주 (YM-2, -3, -4)가 하나의 분지군을, A. culbertsoni, A. polyphaga, HOV주, 및 YM-5가 다른 분지군을 형성하는 것으로 나타났다. 게놈 DNA 상의 변이에 근거하여 볼 때, YM-5 주는 유전적으로 A. culbertsoni와 거의 유사한 분리주이며 한국 분리주는 최소 2종 이상의 가시아메바로 분류할 수 있다고 사료된다. Genetic status of Acanthamoeba spp. were tested on the basis of random amplified polymorphic DNA(RAPD) marker analysis. Four previously established Acanthamoeba species. 4 Korean isolates of Acanthamoeba sp.. and one American isolate of Acanthamoeba sp. were analyzed by RAPD-PCR using an arbitrary decamer primers. Amplification products were fractionated by agarose gel electrophoresis and stained by ethidium bromide. Eighteen primers producted DNA amplification profiles revealing clear differences among 4 species. Nie of them also produced DNA amplification profiles which included some isolate-specific amplification products. On the basis of amplified fragments by 18 primers, the pairwise similarity indices between A. culbertsoni and other species (i.e., A. hatchetti, A. triangularis, A. polyphaga) were 0.300, 0.308, and 0.313, respectively. Similarity index between A. hatchetti and A. triangularis was 0.833. The mean similarity index among the 3 Korean isolates (YM-2,-3,-4) was 0.959 and 0.832 among them and 2 other species (A. hatchetti and A. triangularis). The mean similarity index among YM-5 and other Korean isolates (YM-2,-3,-4) was 0.237. However, the similarity index between YM-5 and A. culbertsoni was 0.857, which suggests that YM-5 is genetically more similar to A. culbertsoni than other Korean isolates. Phenogram reconstructed by UPGMA method revealed that there are two groups: one group consists of A. hatchetti, A. triangularis, and 3 Korean isolates (YM-2,-3,-4), and the other group consists of A. culbertsoni, A. polyphaga, HOV, and YM-5.

      • 일부 사업장 건강증진사업 실태조사 및 요인분석

        이경화,이원철,이강숙,홍현숙,송연이 가톨릭대학교 산업의학센터 2000 韓國의 産業醫學 Vol.39 No.2

        For the purpose of access the health promotion activities in 138 worksite which had more than 50 workers, we surveyed the questionnaire on May and September 1998. The results of survey were as follows: 1.59 companies(45.1%) were conducting the health promotion activities. Most of them were manufacturing and located Kyung-sang province and had nurses as a health manager. 2.Companies operating the health promotion activities had significant higher degree of satisfaction and usage of welfare facilities than non-operating companies. 3.The level of knowledge for regulations, professional skills, and performance related health promotion was low in all companies. Top manager's interest and will for investment to health promotion was significant lower in non-operating companies. 4.The reasons why the health promotion program was not operated, were low budget, top manager's indifference, lack of information, work overloading, no human resource, an insufficient governmental support in order. 5.The most necessary items for program were education and promotion, budget, and governmental support. Needed personnel were nurses, fitness trainner, and necessary program were health management, exercise, nutrition, and stress counselling. For comparing before and after IMF, amount of budget was decreased. In conclusion, this study suggested that major barriers to conduct health promotion activities were lack of budget, lower interest of top managers, and insufficient professional information, therefore detail health promotion program would be developed and supported by government.

      • KCI등재후보

        위탁운영 중학교 급식에 있어 중학생들의 메뉴 기호도 조사

        한경수,홍숙현 한국식생활문화학회 2002 韓國食生活文化學會誌 Vol.17 No.1

        This research aimed to find out menu preference for middle school students and was conducted in a form of questionnaire sampled form middle school students in 10 schools where the meal program under commission was operating in Seoul. The questionnaire was distributed from Dec. 1 to 20, 2000 and gathered menu preference of staple, soup or stew, side dishes and dessert by each meal, season, gender. Statistical data analysis was completea using the SAS package, such as average and standard deviation, frequency analysis and T-test. The results can be summarized as follows : Most of the schools provided rice for lunch, while the students preferred noodles, mandu and bread. Most of students preferd beef rib soup. Gimchi stew with clear soup was favored for breakfast and stews for lunch and dinner. Side dishes were more favored by female students, in which shows the differences between male and female students. Students preferred dessert the most with fruits(4.49). It is required that the quality of school meals should be improved through the service of various kinds of desserts.

      • 肝吸蟲症의 肝癌 誘發 可能性에 對한 發癌物質 3´-methyl-4-dimethylaminoazobenzene의 影響

        閔弘基,鄭慶淑 梨花女子大學校 韓國生活科學硏究院 1986 韓國生活科學硏究院 論叢 Vol.37 No.-

        原發性 肝癌 특히 膽管癌이 肝吸蟲症을 동반하고 있는 예가 간흡충증이 高率로 만연되고 있는 극동 및 동남아의 여러 지역에서 드물지 않게 발견되어 왔으며 이런 현상은 偶然의 合倂일 것이라고 주장되기도 하였으나 그 동안의 疫學的, 病理組織學的 및 實驗的 觀察로 제시된 결과는 이들 兩者 사이의 밀접한 相關性을 강력하게 시사하고 있다. 간흡충증으로 인하여 惹起되는 담관의 腺腫性 增殖과 담관상피세포의 粘液細胞化生은 動物宿主의 차이에 관계없이 나타나는 특징적인 병리조직학적 공통소견인 동시에 암으로 轉化될 수 있는 前殷階의 변화로 看做되고 있으나 간흡충감염만으로는 실험적으로 암을 유발시키지 못하며 某種의 發癌物質의 介入으로 이루어질 것이라는 의견이 支配的이다. 그러나 발암물질을 사용한 실험적 연구가 우리나라에서는 수행된 바 없었다. 본실험은 간흡충감염으로 유발되는 담관조직의 변화에 관한 根本 性狀을 해명하고 발암물징이 이에 미치는 영향을 규명하려는 노력의 一環으로 진행 되었다. 食品染料로 많이 쓰이고 있는 발암물질이며 axo화합물의 하나인 3‘-MeDAB을 간흡충감염 마우스에 투여함으로써 담관상피세포가 암세포로 轉化되어가는 移行期 所見을 경험할 수 있었으나 간흡충 또는 발암물질 단독투여의 경우에 있어서는 암발생 소견을 발견할 수 없었다. 이러한 결과를 근거로, 간흡충감염은 담관상피세포의 화생을 유발하는 先行的 要因의 役割을 하며 3‘-MeDAB은 화생된 세포를 자극하여 惡性化시키는 促進的 要因으로서 담관암 발생에 있어 相互 協同作用을 나타내는 것으로 고려되었다. The main objective of the present study is to observe the effect of a carcinogen, 3'-methyl-4-dimethylaminoazobenzene(3'-MeDAB), on bile duct epithelial cells in Clonorchis-infected mice. The animals used were 90 male BALB/c albino mice, and divided into 3 groups: group I, treated with 0.03% 3'-MeDAB(Kwasei Ind. Co., Seoul, Korea) alone for 12 weeks; group II, given approximately 200 Clonorchis metacercriae alone, and group III, given 200 metacercariae at the end of the 12 week treatment with 0.03% 3'-MeDAB. From the 16th week when the autopsies have commenced, 3 mice were removed at random from each group and examined grossly and histopathologically at 4 week interval up to the 52nd week from the beginning of the experiment. For histopathological examination, liver tissues were stained with hematoxylin-eosin. The results obtained are summarized as follows; 1. The gross findings and histopathological changes observed were remarkable in groups II and III, particularly in group III. Mild to severe mucinous cell metaplasia and goblet cell metaplasia were demonstrable in epithelial cells of the adenomatous hyperplastic glands and the biliary ductules peripheral to the second-order bile ducts. Whereas, in group I there were no significant tissue changes except the lower degrees of bile duct proliferation. cholangiofibrosis and inflammatory cell infiltration which were transient. 2. Mice in groups I and II did not develop tumors at any stage. On the other hand, there were strong histopathological evidences of neoplastic transformation of epithelial cells of the biliary ductules and hyperplastic glandular tissues in 2 out of 30 mice in Group III throughout the observation period. The cells were identified as those of transitional stages in the development of cholangiocarcinoma. With the overall findings it was clear that a carcinogen, 3'-MeDAB, played a potentiating role as a promotor for the turnover of metaplastic biliary epithelial cells induced due to Clonorchis infection into neoplastic cells in mice

      • KCI등재후보

        일부 소방공무원의 음주와 직무스트레스와의 관련성

        강경화,이강숙,김석일,맹광호,홍현숙,정춘화 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.4

        목적 : 소방공무원의 음주량과 직종별 직무 스트레스에 대해 알아보고 보다 나은 스트레스 관리방안과 문제성 음주예방을 위한 프로그램을 모색하기 위해 시도되었다. 대상 : 2000년 7월부터 8월까지 소방공무원 중 구조대원 97명, 구급대원 97명, 화재진압대원 179명,행정대원 116명, 기타대원 49명을 대상으로 설문지를 이용하여 수집된 자료를 분석하였다. 결과 : 소방공무원은 모든 직종에서 승진 및 임금제도의 스트레스 요인 점수가 가장 높았다. 직종별로 직무 내적 요인, 조직에서의 역할, 대인관계, 조직과 풍토, 직장환경과 스트레스 결과 점수에 있어 유의한 차이를 보였다 과음 주자인 경우 직무 내적요인, 직무 스트레스 수준, 개인적 특성, 대처방식의 점수가 높았으나 유의하지 알았다. 음주량은 직무내적 요인 중 업무 피드백과 음의 관련성을, 직무 스트레스 요인 중 역할 갈등은 음주량을 증가시키는 것으로 나타났다. 결론 소방공무원의 가장 높은 직무 스트레스 요인으로는 승진 및 임금제도인 것으로 나타났다. 음주량은 역할 갈등과 같은 직무 스트레스 요인과 관련이 있었으며, 향후 전향적인 음주행태조사를 통해 직무 스트레스 요인이 음주에 미치는 영향을 파악하기 위한 연구가 필요하다고 생각된다. 따라서 본 연구결과를 기초로 소방공무원의 직무 스트레스 요인에 대한 적절한 관리와 정책이 필요한 것으로 사료된다. Objectives : To establish the relationship between alcohol use and job stress among firemen, and to develop a comprehensive health promotion program including stress management and the prevention of problem drinking. Methods : Data was collected from July to August, 2000. Study subjects included 97 rescue workers, 97 emergency medical personnel, 179 fire extinguishers, 116 administrators and 49 others. Results : The firemen displayed higher scores of stress due to promotion-related pres-sures and salary. We found significant differences in job internal factors, job role, inter-personal relationship, organizational norm, work environment and stress outcome among the various jobs. Job internal factors, job stress factors, personal characteristics, coping skills, and stress outcome were higher in heavy drinkers compared with the light and moderate drinkers. Job internal factors and smoking habit showed a positive correlation with the amount of drinking, although coping skill, exercise frequency and monthly income showed a negative relation with the amount consumed. Conclusion : This study suggested that alcohol drinking is associated with job stress. This suggests that a comprehensive health promotion program including stress management and problem drinking prevention and control should be developed.

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