흉선종 제거후에 발생한 재생 불량성 빈혈 : 증례보고

전원선,이상철,김현정,배상병,김찬규,이남수,박노진,이규택,박성규,홍대식,박희숙,원종호 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.2

Thymoma is associated with myasthenia gravis, Pure red cell aplasia, and autoimmune diseases such as autoimmune hemolytic anemia, aplastic anemia, and hypogammaglobulinemia. It's association with aplastic anemia is rare and aplastic anemia appearing after surgical removal of thymoma is especially rare. The authors hereby report a case of aplastic anemia occuring in a patient who was diagnosed with thymoma and myasthenia gravis and had the tumor surgically removed. The patient was treated with anti-thymocyte globulin, cyclosporin, and prednisolone, and showed partial remission with hematologic improvements after 12 months.

재발 또는 불응성 비호즈킨 림프종 환자에서 CDME 구제항암화학요법 후 고용량 항암화학요법 및 자가말초혈액 조혈모세포이식의 효과

김세형,한강원,배상병,김찬규,이남수,이규택,박성규,원종호,홍대식,박희숙 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

Background and objectives : The long-term survival in patients with non-Hodgkin's lymphoma (NHL) after conventional dose chemotherapy is about 35% and the rest of the patients tend to have relapse. So, in relapsed or refractory NHL, we compared the outcome of patients undergoing high-dose chemotherapy with autologous peripheral blood stem cell transplantation(APBSCT) with only salvage chemotherapy of cisplatin, dexamethasone, mitoxantrone, and etoposide(CDME). Materials and methods : From June 1993 to December 1999, 25 patients with relapsed or resistant NHL were treated with CDME regimen as salvage chemotherapy. Twelve patients were received four cycles of CDME chemotherapy, and 13 patients were received high-dose chemotherapy with APBSCT following two cycles of CDME chemotherapy. Results : The median follow-up duration was 12.8 months(range:4-68). The overall response rate was 41.7% (complete response rate 25%, partial response rate 16.7%) in 12 patients with CDME only. Thirteen patients who were treated with high-dose chemotherapy with APBSCT achieved 61.5% complete response rate and 15.4% partial response rate, with an overall response rate of 76.9%. The estimated 3-year progression-free survival rate was significantly higher among patients who received high-dose therapy than patients who received CDME only(41.5% vs 20.0%, p<0.05). And, 3-year overall survival rate was significantly higher among patients who received high-dose therapy(51.3% vs 25.0%, p <0.05). Conclusions : In relapsed or refractory NHL, CDME chemotherapy is an effective salvage chemotherapy and allow peripheral blood stem cell collection. Also, high-dose chemotherapy with APBSCT following CDME is superior to CDME salvage chemotherapy only.

조혈모세포이식환자에서 조혈기능의 회복과 관련된 인자들에 관한 연구

정기주,강명수,권기두,김경하,이상철,김현정,배상병,김찬규,이남수,이규택,원종호,홍대식,박희숙 순천향대학교 의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.1

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폐색전증을 동반한 고환혼합생식세포종양 1례

이규택 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

A 30-year-old male presented with dyspnea and chest pain. Rt radical orchiectomy revealed mixed germ cell tumor and he was diagnosed with stage IV testicular cancer. Mixed germ cell tumor in testis is a rare tumor. Cure rate in ealy stage testicular cancer was above 90% but prognosis in late stage is not good. In three cycles of chemotherapy, β-hCG was not detected in serum, but the lung lesions were seen in the chest X-ray. We recognized that further treatment modalities needed.

세포질내 정자주입법(ICSI)에 있어서 정자흡입 및 난자내 주입방법에 관한 연구

이택후,김항진,송건호,김대근,전상식,박윤규,서태광,전병균,류은경,이은숙,문진수,김광철 경북대학교 의학연구소 2000 경북대학교병원의학연구소논문집 Vol.4 No.1

Study on Method of Sperm Aspiration and Injection into an Oocyte in Intracytoplasmic Sperm Injection(ICSI) Immobilization of spermatozoa prior to intracytoplasmic sperm iniection(ICSI) sometimes results in crooked tail and this makes it difficult to aspirate sperm into an injection pipette tail first. Head-first sperm aspiration into an injection pipette avoid this problem due to the bigger size of the sperm head. The effect of head or tail-first sperm injection into an oocyte on fertilization cleavage, percentage of grade I embryos and development to blastocyst stage in ICSI program has been studied. A single living immobilized spermatozoa from oligoasthenozoospermic patient was injected into an oocyte head-first or tail-first according to the treatment. Eighteen hours after microinjection, oocytes ware inspected for survival and fertilization Fertilized oocytes with two pronuclei were cultured in 30μl drop of mHTF supplemented with 10% heat-inactivated follicular fluid(FF) at 37℃. On day 2. embryo transfer was performed with cleaved embryos. The remaining 2-8 cell stage embryos were co-cultured with BRL cells in mHTF + 10% FF for 72 hours and the developmental stage was observed. The data were analyzed by Analysis of Variance. A total of 164 oocytes from 36 cycles were assigned to earth treatment and ICSI was performed(88 head-first, tail-first). The rates of normal fertilization were 81.8% and 76.3% for head-first and tail-first, respectively. Of the fertilized oocytes, the percentage of cleaved embryos and the percentage of grade 1 embryo among cleaved embryos were 88.9% and 68.8%, 93.1% and 74.1% for head-first and tail-first, respectively. Of the 2-8 cell embryos cultured, 44.4%(16/36) and 50.0%(10/20) for head first and tail first, respectively developed to blastocyst stage. There were no differences in fertilization, cleavage, rates of grade 1 embryos, and development to blastocyst stage. In conclusion, head-first or tail-first sperm injection into an oocyte in ICSI program does not affect fertilization and subsequent embryo development to blastocyst stage in vitro.

中國外債硏究

李圭澤 한국중국문화학회 2002 中國學論叢 Vol.14 No.-

개혁개방 후 중국의 취업정책과 노동력 시장의 변화

李圭澤 한국중국문화학회 2001 中國學論叢 Vol.12 No.-

目前, 中國大陵廳大的市場潛力, 已經咸爲國際的焦點. 中國市場的穩定與健全, 也深深影響着許多國家的經濟發展. 在衆多影響中國經濟的因素中, 勞動力的有效運用是至關重要的. 然而, 中國實施改革闢放以後, 韆着計劃經濟向市場經濟的轉型和市場競爭的加劇, 失業問題愈益喪出, 失業將鐵重咸脅經擴的發展和社會的安定. 目前其經壙正商集約型增長方式轉變, 經濟增長將主要依繫生産要素質量和使用效奉的提高, 以及生産要素總有效縕合等. 經擴增長方式的轉變意味着等量投資所創造約就業機會減少, 脚勞動力的有效需求下降. 國雌, 中國經濟在轉變經濟增畏方式的過程中, 也給增加就業機會帶來不利約影響. 中國的隱性失業和顚性失業畏期拉存, 呈現求職者就業難, 求才者招工也難的局面. 根據中國人日增畏及結構特點, 在末來拒至20率勞動力仍會保持一定增畏, 特別是前10年, 勞動力增畏速度絢達1.5路, 但勞動力索質在短期灼難以根本改變. 國沈, 中國必需加强勞勳力約培訓和再培訓, 提高勞動力的適應性, 以糾正勞動力市場結構性失衡, 最終提高人力贇源的利用效率. 男外, 末T液至10年內, 中國必須建立符合農村I業化和城市化方向, 且具市場化的競爭性就業制度和非戱說性勞動力市場, 通過制定就業促進法和職業介緖法等法規來規範勞動力市場.

固體還元劑에 의한 酸洗廢葉物인 酸化鐵의 充塡層 還元

李大喆,李圭澤 全北大學校 1979 論文集 Vol.21 No.-

In the manufacturing process for obtaining reduced sponge iron from pickling-oxide, the production of sponge iron is strictly controlled by pre-reduction process of the pickling oxide bed by coal coke and anthracite. Consequently for the increased of this product, the fundamental knowleadge of a reduction mechanism of the packed bed has to be reviewed. In this study, time dependences of fractional reduction R for a packed columnar iron oxide bed at 1100℃ were measured for various kind of iron oxides with various particle size, using reducing agents, coal coke and anthracite. Fractional reduction R is measured for ratio of outer diameter of unreacted part r_0 and that of sponge iron r, R=1-(r r_0)^2.

중국 산업별 취업구조 변화 연구

이규택 韓國外國語大學校 外國學綜合硏究센터 中國硏究所 2004 中國硏究 Vol.34 No.-

After China carried out the policy of economic reform and opened its gate to foreign intercourse, market competition in the industry became keen. This caused serious unemployment problems and it threatened economic advance and social stability in China. If Chinese government can't settle these problems, economic development can't be expected in the future. This paper focuses on degrees of contribution of three major industries to national economy, analyzes employment structure, predicts changes in employment by industries after China's joining WTO and helps Korea easily access and approach to China. This study proves that the degrees of contribution of three major industries to GDP in China differs through by industries. GDP component proportion in primary industry shows a downward tendency. In secondary industry it is at a standstill and in tertiary industry it goes on increasing. In the area of employment, after the reform and gate opening, tertiary industry makes great progress and produce output value and employment rate in tertiary industry ascend rapidly. On the contrary, employment rate in primary and secondary industry descends. In the field of foreign investment, foreign capitals imported in primary industry are few. Most of them are invested in secondary industry. The amount of foreign capitals imported in tertiary industry have been slowly increasing. But China's recent joining to WTO accelerates the investment in tertiary industry. After the economic reform, large amount of residuary labor force switched into the labor in industry segment at the early stage was created. From late 1990's, however, increasing unemployment in industry segment caused by industrial structure adjustment such as government-owned enterprise reform made it hard to absorb agricultural labor. Instead of industry segment, tertiary industry embarked itself in absorbing agricultural labor from late 1990's and much of agricultural residuary labor force was switched to tertiary industry labor. This tendency is expected to continue and increase for the time being. Secondary industry in which manufacturing occupies 90% have been decreased from 1998. Among 15 branches of trade in manufacturing 11 branches except sewing, leather, timber processing, electric machine and communication facilities are losing their laborer. It means that there has been a decrease in resources intensive field and traditional branches while labor-intensive maintains its power. Laborers in tertiary industry are increasing each year and the percentage of employment in traditional branches is the highest. The rate of employment increase is higher in emerging branches. Therefore continuous development is expected in these branches. Synthetically, primary industry tends to sink in occupancy rate and the percentage of employment, secondary industry shows the tendency of gradual fall, whereas tertiary industry will develop and increase and ultimately become the core industry which is going to have strong effect on Chinese industrial development.

식품과 식품포장재 중 첨가물 및 중금속 함량에 관한 연구

李丙晁,朴澤奎 건국대학교 1980 學術誌 Vol.24 No.2

A study was carried out on the coloring matters, preservatives and color fixation matters in hall and sausage sampled from 5 companies during the period of two months from August 1, to October 1, 1979, and determined the contents of cadmium and Lead in food packaging materials (PVC) The results were obtained as follows. (1)In ham a mixture of Amaranth and Tartrazine was detected in three (10%), and Amaranth was detected in two (5%) that of Amaranth, Tartrazine and Sunset yellow FCF in one (3.3%) (2)In sausage a mixture of Amaranth auld Tartrazine was found ill 11 (36.7%) that of Amaranth and Sunset Yellow FCF in 9 (30%), Amaranth in 4 (13.3%), Tartrazine 3 (10%) of 30 samples. (3)In ham a mixture of solbic acid and its salts, AF2 was detected in 11 (36.7%) and a mixture of sorbic acid, its salt, AF2 and Nitrofurazone was detected in 9 (30 %) out of 30 samples and that in sausage was a mixture of sorbic acid, its salts and AF2 in 14 (46.7%) and a mixture of sorbic acid, its salt and Nitrofurazone was in 11 (36.7%) out of 30 samples. (4)The concentrations of all the color fixation matter were in the range of 480mg to 2730mg per Kg of samples in ham and of 410mg to 2700mh in sausage (5)The contents of Cadmium and Lead in PVC packaging materials were in the range of 120.5 ㎍/g to 515.3 ㎍/g and 257 ㎍/g to 1.593 ㎍/g respectively.