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정신분열병에 대한 Risperidone의 효과 및 안전성에 관하여
신석철,왕성근,지익성,이선우,이규광,이봉희,이진영,황선희,신용재,배경도,김정란 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1
In order to evaluate the efficacy and safety of risperidone, 10 patients with chronic schizophrenia were examined for 8 weeks in a silgle-open study. After the wash-out period of 1 week, risperidone was administered. Efficacy was evaluated by means of Positive and Negative syndrome Scale for Schizophernia(PANSS) and Clinical Global Impression(CGI). Safety assessment included the Extrapyramidal Symptom Rating Scale(ESRS), vital signs, body weight, ECG, and laboratory tests. The results were as follows 1) On the PANSS total score, there was significant improvement of total score after 1 week (P<.05) of administratiom. 2) On the PANSS positive and negative subscal, there were significant improvement of posotive and negative scores after 2 weeks (P<.05) of administration. 3) On the PANSS general psychopatholgy subscals, there were significant improvement of general psychopathologyscores after 1 week (P<.05) of administratiom. 4) On the CGI, there was significant decreasement of clinical impression of severity of schizophrenia score after 2 week (P<.05) of administration. 5) A statistically significant increase in body weight (P<.05) was observed after 8 weeks of administration. 6) EPS reached the peak at the end of the 1st week of administration of risperidone (11.8± 24.25) but they were easily relieved by addition of benztropine and clonazepam. There was not significant change in laboratory tests, vital sign, ECG after 8 weeks of administration. These results suggest that Risperidone is an effective antipsychotics and clinically safe except for increased body weight in chronic schizophrenia.
화학적 요부 교감신경절 차단에서 한 분절 차단과 두 분절 차단의 비교
김종일,이규종,이상곤,민병우,반종석,문철준 대한마취과학회 2001 Korean Journal of Anesthesiology Vol.41 No.4
Chemical Lumbar Sympathetic Block: Comparison of One- Versus Two-needle Techniques Chul-Jun Mun, M.D., Kyu-Jong Lee, M.D., Sang-Gon Lee, M.D., Jong-Il Kim, M.D.^* Jong-Suk Ban, M.D., and Byung-Woo Min, M.D. Department of Anesthesiology, Fatima Hospital, Daegu, Korea ^*Kim Jong Il Pain Clinic, Daegu, Korea Background: It was frequently noticed in the course of performing a two-needle sympathectomy, that satisfactory spread of contrast solution could be produced by injection through only one of the needles. This led to a closer examination of the merits of single-needle technique. Methods: Forty patients were randomized into two groups. Patients in the single-needle group (n = 20) were injected at the second or third lumbar sympathetic ganglia, while patients in the two-needle group (n = 20) were injected at the second and thired lumbar sympathetic ganglia. Lumbar sympathetic blocks were performed using 3 ml of alcohol and the spread of injectate was verified with C-arm fluoroscopy. The indicators of a successful sympathetic block are increasing skin temperature, decreasing pain, and anhidrosis in the distal extremity. Results: The duration of anhidrosis was 12.2 ?? 2.6 months (mean ?? SD) in the single-needle group versus 13.6 ?? 3.6 months (mean << SD) in the two-needle group. Conclusions: As these results were not significantly different from those obtained in patients having considered to be effective for a neurolytic ;i,bar sympathectomy. (korean J Anesthesiol 2001; 41: 439~443)
이성규,강석규,이동호 漢陽大學校 工學技術硏究所 2001 工學技術論文集 Vol.10 No.-
본 논문에서는 움직임 보상을 이용한 움직임 기반의 디인터레이싱 알고리즘을 제안한다. 정확한 움직임 추정을 위해 전처 리로서 EBMF(Edge Based Median Filter)를 사용하며 2 개의 같은 위상을 갖는 필드와 1개의 다른 위상을 갖는 필드를 이용한 새로운 BMA(Block Matching Algorithm) 움직임 보상 방법을 제안한다. 시간축 필터로서 모션 미싱 에러를 제거하기 위해 입력 영상의 움직임 영역에 따라 각각 다른 임계값을 적용하는 AMPDF(Adaptive Minimum Pixel Difference filter)를 적용하였으며 MMD(Maximum Motion Detection)와 SAD(Sum of Difference)를 이용하여 빠른 움직임 영역에서 화질을 향상시켰다. 최종적으로 잘못된 움직임 보상에 기인하는 화질의 열화를 방지하기 위한 후처리로서 움직임 보정 필터를 제안한다. 모의 실험을 통해 제안하는 방법이 기존의 방법에 비해 우수한 성능을 갖는 것을 확인하였다. In this paper, we propose a motion-adaptive de-interlacing method using motion compensated interpolation. In a conventional motion compensated method, a simple pre-filter such as line averaging is applied to interpolate missing lines before the motion estimation. However, this method causes interpolation error because of inaccurate motion estimation and compensation. In the proposed method, EBMF(Edge Based Median Filter) as a pre-filter is applied, and new matching method, which uses two same-parity fields and opposite-parity field as a reference, is proposed. For further improvement, motion correction filter is proposed to reduce the interpolation error caused by incorrect motion. Simulation results showed that the proposed method provides better performance than existing methods.
이종석,이성열,박영립,서용원,황규왕 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.1
Follicular stem cell was assumed as a hair matrix cell. But, recently it was suggested that follicular stem cells were in the bulge portion of outer root sheath of hair follicles, and its proofs were reported. We tried to culture outer root sheath keratinocytes in the bulge portion of human hair follicles, and it would be experimental base for many factors and drugs realated with hair growth and differentiation. The outer root sheath keratinocytes were isolated from plucked human hair follicles, and could be serially passaged for up to 2 times on used biologic feeder cell layer.
TSC 합성보의 제작방법에 따른 구조적 거동에 관한 실험적 연구
이지운,김도훈,김성배,이창남,김상섭,김규석 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)
Composite action can be achieved by providing shear connectors between steel top flange and concrete topping. Composite sections have larger stiffness than the summation of the individual stiffness of slab and beam, therefore, can carry larger load or similar loads with appreciably smaller deflection and are less prone to transient vibration. T-type Steel Composite beam(TSC-beam) is developed and tested. To make the part of steel beam, we used the way of welding two steel plates as well as the way of folding one steel plate.
청소년의 스포츠활동 참가유무와 학교생활 적응에 관한 연구
이학래,김석규 漢陽大學校 體育科學硏究所 2003 體育科學 Vol.23 No.23
This study in order to make sure the relationship between adolescents sports activity and the fitness of school life, at first I examine the difference of school life's fitness according to the sport activities experience. Second, this study was to examine the effect of sport activities on the fitness of school life. To make use of Stratified Cluster Random Sampling Method, all 320students(160 participants, 160 non-participants) being in middle & high school sin Seoul presently were selected as a sampling group, the only half of whom have the experience of sports activity participation. Questions are made up of such variables as a characteristic of a home back ground, sports activity participation and the fitness of school life. Dependability and appropriateness of questions were verified through improvement of question quality, preliminary inspection, investigation of literature studies and experts' conference. Especially as a result of questions about the fitness of school life by preliminary inspection those questions showed comparatively high dependability that the price of alpha comes to be 0.637. And statistics method used for data analysis in this study are Frequencies, ANOVA. By verifying experimentally an hypothesis about the relationship between sports activity participation of adolescents and the fitness of school life, acquired results are as follows. Participation in sports activity has an effect on adolescents the fitness of school life. In general the rate of the fitness by participants group in sports activity is higher than the rate of non-participants group.
인터넷 메타데이타 검색 및 관리 시스템의 설계 및 구현
이원석,박경용,양영종,정효택,김순용,이규철 한국문헌정보학회 1997 한국문헌정보학회지 Vol.31 No.2
인터넷은 디지탈 형태의 다양한 정보를 신속하게 전달한다는 점에서 매우 각광을 받고 있다. 그러나, 대량의 인터넷 정보 중에서 자신이 원하는 정보 자원을 정확하게 많이 얻어 낼 수 있는 방법의 제공은 매우 어려운 문제이다. 본 논문에서는 인터넷 정보 자원의 메타데이타를 관리하기 위해 SeriCore라는 SGML 형식의 메타데이타 DTD(Document Type Definition)를 정의하고, 이들 메타데이타를 효율적으로 저장하고 검색, 관리할 수 있는 시스템을 설계, 구현하였다 The Internet has gained popularity because ot provides various information in digital format. However, it is very difficult to provide methods which make it possible to search adequate information resource from bulk of Internet information. In this paper, we define a SGML metadata DTD, named SeriCore, and design and implement a metadata retrieval and management system which can store, retrieve and manage the Internet metadata efficiently
이규식,박정민,김태곤,홍석구 慶北專門大學 2003 慶北專門大學 論文集 Vol.22 No.-
It investigates the website and a technique in order to make the culture property of the area with digital contents, it presented a method to make digital contents through investigation of Young-Ju area culture property. The results of this study ① It minimizes the loss of information ② Must come to be processed with the form which corresponds in objective of information delivery ③ for the result, It is necessary to grafting on new digitizing techniques.