TiN 피막처리된 Co-Cr계 교정용 선재의 마찰저항력

이호규,권오원,김교한 대한치과교정학회 1998 대한치과교정학회지 Vol.28 No.1

TiN ion-plating된 Co-Cr 선재(.016", .016"x.022")와 ion-plating되지 않은 선재(.016", .016"x.022")를 이용하고, 3가지 종류의 브라켓(TiN ion-plating된 금속 브라켓, 세라믹 브라켓 및 플라스틱 브라켓)을 대상으로 마찰실험을 행하고, 거기에서 얻어진 마찰 특성곡선과 곡선으로부터 구한 최대 정지마찰력, 그리고 선재와 브라켓의 표면양상을 주사 전자 현미경으로 관찰하여 TiN ion-plating의 효과를 검토한 결과 다음과 같은 결론을 얻었다. ·3가지 종류의 브라켓에 TiN ion-plating된 선재를 사용한 경우의 마찰력은 TiN ion-plating되지 않은 선재를 사용한 경우의 마찰력보다 각각 통계학적으로 유의성 있게 낮았다(P<0.05). ·3가지 종류의 브라켓에 원형선재를 사용한 경우의 마찰력은 각형 선재를 사용한 경우의 마찰력보다 각각 통계학적으로 유의성있게 낮았다(P<0.05). ·원형 선재를 사용한 경우 TiN ion-plating되지 않은 선재를 사용한 경우가 TiN ion-plating된 선재를 사용한 경우보다 선재 및 브라켓 슬롯의 표면이 더욱 거친 양상을 나타내었다. ·각형 선재를 사용한 경우 전반적으로 원형 선재를 사용한 경우보다 선재 및 브라켓 슬롯의 표면이 더욱 거친 양상을 나타내었다. ·TiN ion-plating된 원형 선재를 사용한 경우 정지마찰력과 운동마찰력의 차는 별로 없었으나 TiN ion-plating된 각형 선재를 사용한 경우 정지마찰력은 운동마찰력보다 높았다. ·TiN ion-plating되지 않은 선재를 사용한 경우가 TiN ion-plating된 선재를 사용한 경우에 비해 정지마찰력이 운동 마찰력보다 훨씬 높았다. The effectiveness of TiN ion-plating was examined with TiN ion-plated Co-Cr wires(.016", .016"x.022") on three different types of bracket(TiN ion-plated metal bracket, ceramic bracket and plastic bracket) Maximum static frictional forces and characteristic curves obtained from the frictional characteristic graph, were compared and surface roughness of wires and bracket slots before and after friction experiment was observed by SEM. The obtained results were as follows : ·The frictional forces of TiN ion-plated wires were significantly lower than those of non ion-plated wires(P<0.05) ·On the effect of wire shape, the frictional forces of round wires were significantly lower than those of rectangular wires(P<0.05). ·As the result of the SEM observation on the wires and bracket slots after the friction experiment, the surface of non ion-plated wires was rougher than that of TiN ion-plated one. ·The difference between the static frictional forces and the kinetic frictional forces was not significant in case of TiN ion-plated round wires, but the static fictional forces were a little higher than the kinetic frictional forces in the TiN ion-plated rectangular wires. ·The static frictional forces were much higher than the kinetic frictional forces in the case of non ion-plated wires.

그레이브스 병 치료 후 재발 위험 인자에 관한 연구

이영창,유명희,윤석기,변동원,서교일,김극배 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.2

연구 배경 : 그레이브스 병에 대한 항갑상선제 치료후 적절한 치료 여부 평가 및 재발 위험성을 예측하기 위하여 여러 가지 예후 판정 인자들이 연구되어 왔으며, 이러한 인자들 중 TRH(thyrotropin-releasing hormone) 자극 시험이 가장 믿을 만한 검사중에 하나로 알려져 있다. 그러나 TRH 자극 검사가 정상으로 나와도 재발하는 경우가 많으며, 현재로는 이러한 경우에 재발을 예측하는 예후 인자에 대한 연구는 전무한 실정이다. 금번 연구에서는 TRH 자극 시험 후 TSH(thyroid stimulating hormone)가 정상적인 반응을 보인 환자를 대상으로 재발 및 관해여부를 예측할 수 있는 인자들을 찾고자 하였다. 대상 및 방법 : 항갑상선제제 치료 종료후 TRH 자극 시험을 시행하였던 그레이브스 병 환자 총 84명 중, 정상적인 TSH 반응을 보이면서 1년 이상 추적 관찰이 가능하였던 32명의 환자를 대상으로 하였다. 처음 진단 시와 치료 종료 시에 T3(triiodothyronine), T4(thyroxine), T3/T4 비, TSH, TRAb, Anti-TPO Ab(anti-thyroperoxidase antibody)를 측정하였으며, 치료 종료 2개월후에는 TRH 자극 검사를 하여 TSH 증가폭(△TSH) 및 유리 T_(3) 증가폭(△FT_(3))을 구하였다. 모든 측정치는 평균±표준편차로 표시하였으며, SPSS software를 이용하여 Student's paired t-test, chi-square test, Wilcoxon signed ranks test를 시행하였고, 유의 수준 0.05 이하를 통계적으로 유의하다고 판단하였다. 결과 1) 총 32명의 환자 중 재발한 환자(Group Ⅰ)는 22명(69%) 이었으며, 재발한 환자(Group Ⅱ)는 10명(31%) 이었다. 2) 진단 초기 총T3 치는 Ⅰ 군에서 342.0±126.2ng/dl, Ⅱ 군에서 493.0 ±142.2 ng/dl로 Ⅱ군에 비해 유의하게 증가되었다(p<0.05). 3) Anti-TPO Ab는 Ⅰ군에서 2.9±4.4, Ⅱ군에서 22.3±22.3 U/mL로 나타나 Ⅱ군에서 유의하게 증가되었다.(p<0.05) 4) 양군에서 치료 종료후 재발시 대부분의 환자가 1년 이내에 재발하였다. 5) TRH 자극· 검사후 유리 T3 증가폭 및 TSH 증가폭은 양군간에 차이가 업ㅅ었다(1.5±0.9 vs 1.2±1.0 pmol/L, 12.54±7.56 vs 11.23±4.21 mU/L, p>0.05) 결론 : TRH 자극 검사후 정상적인 TSH 반응을 보인 환자에서 재발 및 관해여부를 치료 초기 T3 및 치료 종료시 Anti-TPO Ab로 예측할 수 있었으며, 이들 측정치가 증가해 있을수록 재발의 가능성이 많음을 알 수 있었다. 또한 투약 중단후 초기 12개원의 추적기간 동안 관해가 유지되면 그 이후엔 재발의 가능성이 현저히 줄어 들었으며, 이 후 좀더 많은 환자들을 대상으로 하는 장기적인 추적연구가 진행 되어야 할 것으로 사료된다. Background : Many studies were undertaken to find parameters that could predict the clinical course of patients with Graves' disease after withdrawal of antithyroid drugs. In many parameters, TRH (thyrotropin-releasing hormone) stimulation test and T3 suppression test were considered to be one of the most reliable for predicting remission. But recently, some studies showed that the measurement of free T3 and FT3 are to be a more accurate than other thyroid function test. In this study, we measured T_(3), T_(4), T_(3)/T_(4), TSH (thyroid stimulating hormone), TRAb (TSH receptor antibody), FT3 and other known useful parameters to compare the factors influencing the relapse of Graves disease after antithyroid medication. Patients and methods : Among the 84 Graves' disease patients who had done the TRH stimulation test after withdrawal of antithyroid medication, we examined 32 patients who showed normal TSH response and followed up more than one year. T_(3), T_(4), T_(3)/T_(4), TSH and TRAb levels were measured at the time of diagnosis and at the end of therapy. Serum TSH and FT_(3) levels were measured after TRH stimulation, after two months of withdrawal of medication. Statistical evaluation was Performed by SPSS software in combination with Student's Paired t-test, chi-square test, Wlicoxon signed-ranks test. p-value less than 0.05 was considered to be significant. Results 1. In the 32 patients with Graves disease, 10 patients(31%) relapsed(Group Ⅰ) and 22 Patients(69%) remained in remission(Group Ⅱ). 2. Initial serum T3 level was significantly higher in group Ⅰ than group Ⅱ(342.0 ±126.2 vs. 493.0±142.2 ng/dl, p<0.05). 3. Anti-TPO Ab level was significantly higher in group Ⅰ than group Ⅱ(22.3±22.3 vs 2.9±4.4 U/mL, p<0.05). 4. In group Ⅰ and Ⅱ most patients showed relapse within 1 year after antithyroid medication. 5. After TRH stimulation test, serum FT_(3), and TSH level were not significantly different between group I and Ⅱ(p>0.05). 6. Serum T_(4), T_(3)/T_(4), TSH, TRAb levels were not significantly different from group Ⅰ and Ⅱ. Conclusion : In this study, we found increased relapse rate in the patients with Graves' disease whose initial serum T3 and anti-TPO Ab levels were high, so these parameters could be used to predict the relapse of Graves' disease. In the case of more than 12 months remission period after withdrawal of antithyroid medication, no relapse wsa observed in this study, but study should be done in the large population of patients with Graves' disease.

만성신부전증 환자에서 Recombinant Human Erythropoietin 치료에 따른 혈액지표와 Hemoglobin A1c에 대한 연구

이세영,배성한,변동원,서교일,유명희,김극배 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.2

Hemoglobin A1c is produced by a progressive, non-enzymatic reaction between glucose and hemoglobin within the erythrocytes. The HbA1c concentration is dependent on the plasma glucose level and the stage of development of the erythrocytes. Immature erythrocytes contain lower levels of glycosylated hemoglobin than mature erythrocytes. HbA1c level was decreased in short RBC life span. Therefore, HbA1c level is not only measure for assessment of moderate to long term glycemic status in diabetics, but also as a possible diagnostic parameter of anemia. The aim of this study was to evaluate the HbA1c level in patients with chronic renal failure with anemia. HbA1c concentration, iron, ferritin, TIBC and hematologic parameters were measured before treatment and 1, 2 months after administration of recombinant human erythropoietin. The HbA1c concentration was measured by high performance liquid chromatography with cation exchange column (Pharmacia). The results were as follows; 1. The mean of hemoglobin was 8.66 g/dL in the controls and 7.84 g/dL in the patients with chronic renal failure. The mean of hematocrit was 25.19 % in the controls and 23.14 % in the patients with chronic renal failure. The mean of MCV was 93.23 fL in the controls and 92.73 fL in the patients with chronic renal failure. The mean of MCH was 32.56 pg in the controls and 31.76 pg in the patients with chronic renal failure. The mean of HbA1c was 3.15 % in the controls and 2.95 % in the patients with chronic renal failure. 2. Hematologic parameters in the patients with chronic renal failure 1) The results of hemoglobins were 7.84 g/dL, 8.11 g/dL, 8.92 g/dL, the MCH were 31.76 pg, 32.87 pg, 33.20 pg, the results of MCV were 92.73 fL, 97.37 fL, 92.85 fL at before treatment and 1, 2 months after administration of r-HuEpo. 2) The results of hematocrits were 23.14 %, 23.73 %, 26.73 % at before treatment and 1, 2 months after administration of r-HuEpo. 3. Iron metabolism parameters in the patients with chronic renal failure 1) The results of iron test were 180.92 ㎍/dL, 137.79 ㎍/dL, 126.83 ㎍/dL at before treatment and 1, 2 months after administration of r-HuEpo. 2) The results of ferritin test were 1500.2 ng/ml, 1311.6 ng/ml, 1151.0 ng/ml at before treatment and 1, 2 months after administration of r-HuEpo. 3) The results of TIBC test were 282.17 ㎍/dL, 282.45 ㎍/dL, 278.83 ㎍/dL at before treatment and 1, 2 months after administration of r-HuEpo. 4. The results of HbA1c test were 2.95 %, 3.08 %, 3.18 % at before treatment and 1, 2 months after administration of r-HuEpo. It is suggested that, in patients with chronic renal failure, evaluation of HbA1c in diabetics who have anemia with chronic renal failure should be consider possible hematologic parameters, and HbA1c level would be one of the marker of anemia status, but further studies are needed.

전립선 선암종에서의 p53 및 I-cadherin 단백의 면역조직 화학적 연구

맹이소,김원일,이교영,김영신,강창석,심상인 대한병리학회 1998 Journal of Pathology and Translational Medicine Vol.32 No.3

경기관지폐생검의 진단적 가치

이원식,정태훈,김교선,이국희,유덕종,손명원 대한내과학회 1986 대한내과학회지 Vol.30 No.2

The diagnostic value of transbronchial lung biopsy(TBLB) through fiberoptic bronchoscope was studied in 61 patients with diffuse or localized lung disease in which routine clinical and laboratory examinations revealed no diagnostic clue. By the technique adequate tissue specimen for diagnosis was obtainable in 28 of 33 patients (78.8 percent) and 25 of 28(89.3 percent) with localized and diffuse lung diseases, respectively. A histological diagnosis was possible in more than 75 percent of the patients with lung cancer proved by various means. On the other hand, in patients with tuberculous lesions, diffuse or localized, the incidence of positive diagnosis was less than a half. The complications among 61 patients underwent the TBLB were pneumothorax in one and hemoptysis in three, which subsided spontaneously. These facts suggest that the TRLB is a relatively safe, and more useful in the diagnosis of cancer of the lung than in inflammatory disease.

1-Bromoacetylpyrene 誘導體化劑를 利用한 Carboxyl基 含有成分의 分析에 관한 硏究(Ⅰ) : 高級不飽和脂肪酸의 HPLC에 依한 定量 Determination of Unsaturated Fatty Acids by HPLC

李允中,曺正吉,朴元敎,李康春 成均館大學校 科學技術硏究所 1988 論文集 Vol.39 No.1

A simple and highly sensitive method for the determination of unsaturated fatty acids (C_16:1, C_20:4, C_20:5) is described. I-Bromoacetylpyrene was used as the pre-column fluorescent labelling reagent for HPLC. Fatty acids were derivatized quantitatively into fluorescent compounds by treating with 1-bromoacetylpyrene in the presence of 18-crown- 6 in acetonitrile. The optimum conditions for the derivatization such as, concentrations of KOH, 18-crown-6, and 1-bromoacetylpyrene, reaction temperature and reaction time, were investigated. The derivatives were separated on a reversed phase column (LiChrosorb RP-8, 5 ㎛) using the tertiary mixture of acetonitrile, methanol, and water as the mobile phase. The effluent was monitored by fluorometer (excitation wavelength; 366 nm, emission wavelength; 454 nm). Linearities of calibration curve were obtained between 5.0 p mol and 40.0 p mol. The detection limit of fatty acids was 1 p mol in a 20μl of injection volume.

대구전시컨벤션센터(EXCO) 확장의 필요성과 기대효과

서민교,서동욱,이원복 대구대학교 경제경영연구소 2006 경제경영연구 Vol.4 No.1

Recently, the exhibition and convention industry in many countries, including Korea has rapidly grown. Also the local government recognizes it as a prospective emerging industry and has built exhibition and convention centers to promote its development. Daegu city also has built EXCO(Daegu exhibition & convention center) in 2001 to develop the exhibition and convention industry. The purposes of this study are as follows; 1. To investigate the current situation and performance of EXCO 2. To analyze the necessity and expected effects of EXCO expansion. 3. To search for ideas and suggestions to spur the development of the Daegu-Kyung Buk exhibition and convention industry.

프랑스語의 문화적·언어적 背景

오원교,이명숙 慶北大學校 語學硏究所 1989 語文硏究 Vol.14 No.-

Cd_(1-x)Zn_xS/CdTe 이종접합 태양전지의 구조 및 전기적 특성에 관한 연구

송우창,이상교,심낙순,박종국,김원종 三陟大學校 2001 論文集 Vol.34 No.1

In this paper, the processing conditions and the various methods to improve the efficiency of the Cd1-xZnxS/CdTe solar cells were studied. Cd1-xZnxS films were grown by chemical bath deposition (CBD), which is a very attractive method for low-cost and large-area solar cells. To improve the electrical conductivity of Cd1-xZnxS films, thin indium films(10-40nm thickness) were evaporated on the surface of Cd1-xZnxS films. Experimental parameters such as indium film thickness, Zn mole fraction, and the annealing temperature in terms of structural and electrical properties of Cd1-xZnxS films were investigated. The diffusion process was carried out by heating the sample in air at 150-550℃ for 20 minute. The open circuit voltage of Cd1-xZnxS/CdTe solar cells increased due to reduced electron affinity difference between Cd1-xZnxS and CdTe films. However, the conversion efficiency of Cd1-xZnxS/CdTe solar cell decreased because of the higher series resistance(Rs) than CdS/CdTe solar cell. The series resistance and conversion efficiency of Cd1-xZnxS/CdTe solar cell were improved by using indium-doped Cd1-xZnxS films as windows layer. Cd1-xZnxS/CdTe solar cells fabricated with optimal conditions exhibited Voc=630㎷, Jsc=38.89㎃/㎠ and □=13.19%

간내 포충낭 1예

김정미,최교원,이헌주 영남대학교 기초/임상의학연구소 2001 Yeungnam University Journal of Medicine Vol.18 No.1

In humans, echinococcal species produce cystic lesions primarily involving the liver and lung. Echinococcal infection is caused far more commonly by Echinococcus granulosa than by E. multilocularis, which accounts for less than 5 per cent of all cases of hydatid liver disease. Hydatid disease occurs principally in sheep grazing areas, particularly in the Australia, New Zealand, Greece, Yugoslavia, Middle East, and South American countries, but with increasing migration and traveling, this disease now has a worldwide distribution. This disease is rare in Korea and only few cases have been reported. This is a clinical case report of hydatid cyst of liver caused by Echinococcus granulosus in a 52-year-old man who had been dispatched in the Vietnam from 1966 to 1968.