Variation in clinical usefulness of biomarkers of acute kidney injury in young children undergoing cardiac surgery

Baek, Hee Sun,Lee, Youngok,Jang, Hea Min,Cho, Joonyong,Hyun, Myung Chul,Kim, Yeo Hyang,Hwang, Su-Kyeong,Cho, Min Hyun The Korean Pediatric Society 2020 Clinical and Experimental Pediatrics (CEP) Vol.63 No.4

Background: Acute kidney injury (AKI) is one of the most significant postoperative complications of pediatric cardiac surgery. Because serum creatinine has limitations as a diagnostic marker of AKI, new biomarkers including neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (KIM-1), and interleukin-18 (IL-18) are being evaluated to overcome these limitations and detect AKI at an early stage after cardiac surgery. Purpose: This study aimed to investigate the clinical usefulness of these biomarkers in young children. Methods: Thirty patients with congenital heart diseases who underwent cardiac surgery using cardiopulmonary bypass (CPB) were selected, and their urine and blood samples were collected at baseline and 6, 24, and 48 hours after surgery. Serum creatinine and blood urea nitrogen levels as well as NGAL, KIM-1, and IL-18 levels in urine samples were measured, and clinical parameters were evaluated. Results: Of the 30 patients, 12 developed AKI within 48 hours after cardiac surgery. In the AKI group, 8 of 12 (66.6%) met AKI criteria after 24 hours, and urine KIM-1/creatinine (Cr) level (with adjustment of urine creatinine) peaked at 24 hours with significant difference from baseline level. Additionally, urine KIM-1/Cr level in the AKI group was significantly higher than in the non-AKI group at 6 hours. However, urine NGAL/Cr and IL-18/Cr levels showed no specific trend with time for 48 hours after cardiac surgery. Conclusion: It is suggested that urine KIM-1/Cr concentration could be considered a good biomarker for early AKI prediction after open cardiac surgery using CPB in young children with congenital heart diseases.

養液濃度와 培地種類가 Black Olympia 포도나무의 生育과 果實品質에 미치는 影響

김희곤,김광수,김월수,임경호,최경주,김상철,김병삼 全南大學校 農業科學技術硏究所 1999 農業科學技術硏究 Vol.34 No.-

본 硏究는 養液栽培時 養液濃度와 培地種類가 대립계 포도품종인 Black Olympia의 生育과 果實品質에 미치는 영향을 구명하고자 하였다. 新梢長은 0.5배에서 1.5배의 양액농도에서 농도가 높을수록 길었고, 배지종류별로는 0.5배 농도에서는 밭흙과 퇴비를 1:1로 혼합한 배지에서 신초장이 길었으나 1.5배 농도에서는 오히려 짧게 나타났다. 節間長은 저농도의 양액농도에서는 밭흙과 퇴비를 혼합한 배지가 길었으나 1.5배의 고농도에서는 차이를 보이지 않았다. 각 배지에서 濃度가 높을수록 간경이 크게 나타났으며 배지종류간에는 펄라이트와 버미큘라이트 혼합배지가 밭흙과 퇴비를 혼합한 배지보다 컸으나 유의차가 없었다. 果房重은 각 배지에서 1.0배의 양액농도가 가장 무거웠으며 배지 종류간에는 밭흙과 퇴비를 혼합한 배지가 더 무거웠다. 糖度는 각 배지의 1.0배 양액농도가 높았으며 배지종류간에는 차이를 보이지 않았다. 果皮의 안토시아닌 함량은 배지별로 밭흙과 퇴비를 혼합한 배지에서 높았으며 양액농도별로는 1.0배에서 높게 나타났다. 收量은 펄라이트와 버미큘라이트를 혼합한 배지에서 양액농도가 높을수록 많았으나 밭흙과 퇴비 혼합배지에서는 1.0배의 농도에서 높게 나타났다. This study was carried out to investigate the effects of ionic strength and substrates on growth and fruit quality, and to establish fruit tree nutrient solution culture. The higher ionic strength showed the longer shoot length of grape. Among the substrates, upland soil+compost showed longer shoot length than perlite+vermiculite in 0.5 strength but shorter in 1.5 strength of Hoagland solution. Internode length was longer in upland soil+compost than in perlite+vermiculite in 0.5 strength, but there were no significance in 1.0 and 1.5 strength of Hoagland solution. Higher ionic strength and/or perlite+vermiculite of substrates showed tricker in trunk diameter than lower ionic strength and/or upland soil+compost. Cluster weight was heavier in 1.0 ionic strength than the others. Cluster weight in upland soil+compost was heavier than that of perlite+vermiculite. Soluble solids content of berry was the highest as much as 17.3。 Bx on 1.0 ionic strength of three strength, but there are no significances in substrates. Anthocyanin content of grape skin was higher in upland soil+compost than perlite+vermiculite, as well as the highest in 1.0 strength among three strengths. The higher ionic strength showed the more berry set. Each substrate showed uniformal berry set and growth. The best result in berry yields was obtained in 1.0 ionic strength with substrate of upland soil+compost in comparison to other treatments.

Failure Diagnosis Method of Photovoltaic Generator Using Support Vector Machine

Kyeong‑Hee Cho,Hyung‑Chul Jo,Eung‑sang Kim,Hyang‑A. Park,박준호 대한전기학회 2020 Journal of Electrical Engineering & Technology Vol.15 No.4

The capacity of photovoltaic (PV) generators can increase owing to the 4030 policy of the Government of South Korea.. In addition, there has been signifcant interest in developing a technology for the maintenance of PV generators owing to an increase in the number of outdated PV generators. This paper describes a failure diagnosis method that uses operational data for power generation and solar radiation of PV generators. The measured data stored since four years in an operational 50-kW PV generator that was installed in 2014, were analyzed. The proposed failure diagnosis logic uses support vector machine classifcation as a failure diagnosis method that can classify normal and failure data. The failure data were processed to be used as the fault diagnosis logic for solar power generators. A new 50-kW PV generator, which contained no fault data, was used for a case study in this paper. Fault data were generated and the operation data of the PV generators were diagnosed by applying the proposed method. In addition, the accuracy was calculated and the results were analyzed.

위절제술 환자의 표준진료지침 개발 및 적용 효과

김은희,김철규,이순교,김순덕,이혜옥,권정순,이경미,이민미,심순미,유용만,신종식,강은희,이상일,김병식,오성태,육정환,박수길 한국의료QA학회 2003 한국의료질향상학회지 Vol.10 No.2

Background : Gastric cancer is the most common malignant tumor in Korea. surgical operation is one of the major treatment modalities for gastric cancer patients. Therefore, gastrectomy is one of the most common procedures in General Surgery. There were variation in length of hospital stay and medical treatment for gastrectomy between three surgeons at Asan Medical Center. Clinical pathways have received considerable attention as a tool for recucing the medical practice variation, increasing the efficiency of care process, and improving the quality of care. The aim of this study was to evaluate the effect of a clinical pathway for gastrectomy in gastric cancer patients. Methods : The clinical pathway for gastrectomy was developed and implemented by a multidisciplinary group in Asan Medical Center. A computerized clinical pathway program was developed and revised after a pilot test. A total of 145 patients underwent gastrectomy by three surgeons at Asan Medical Center. We compared the length of hospital stay, patient satisfaction, and unplanned readmission rate between the pre-pathway group(n=67) and the post-pathway group(n=78). We also investigated the degree of satisfaction among the physicians and nurses who were main end-users of the clinical pathway. Results : The clinical pathway was applied to all target patients. The average length of hospital stay was shortened from 12.7days to 10.6days(p<0.01). The degree of patient satisfaction with the care process changed from 90.3% to 89.2% after the implementation of the clinical pathway, but the difference was of satistically significant(p=0.761). Unplanned readmission rate was 2.9% in the pre-pathway group. More than 90% of physicians and nurses answered that the clinical pathway had been a useful tool in their medical practice. Conclusions : The findings of the study demonstrated that implementation of the clinical pathway for gastrectomy produced substantial reduction in the length of hospital stay while improving the quality of patient outcomes. The computerized clinical pathway program can be used as one of the powerful patient management tools for reducing the practice variations and increasing the efficiency of care process in Korea hospital settings.

경정맥 신우조영술중 파열된 자궁의 악성혼합뮬러리안 종양 1예

조희정,김태희,김정식,이해혁,남계현,김희경 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

The Malignant Mixed Mullerian Tumor(MMMT) of uterus, a biphasic malignant tumor composed of both epithelial and stromal component, is rare but very aggressive and generally lethal. Most of these tumors arise spontaneously in the sixth to eighth decade of life, but certain proportions are known to be occurred in women, who had received pelvic irradiation. But, the precise role of irradiation in the genesis of uterine neoplasia remains uncertain. We experienced a case of MMMT of uterus which ruptured during intravenous pyelogram and she had received pelvic irradiation 40years ago.

건강식품 바이탈 및 비지놀의 抗疲勞 效果에 관한 연구

정경수,김혜경,김희수,김계양,곽영숙,김학범 충남대학교 약학대학 의약품개발연구소 1993 藥學論文集 Vol.9 No.-

As a result of extensive research efforts on the oriental medicinal herbs, some of their interesting biological activities have been elucidated. In the present study, antifatigue effects of two natural food supplements consisting of oriental herbs, Vital and Vigilor, were investigated using the ICR mice. The mice were fed with antibiotic-free normal mouse feed containing Vital or Vigilor for 14,28, or 31 days and then subjected to forced swim tests. In a test carried out in melting-ice water, Vital and Vigilor significantly increased the exhaustion times of the 28 day-fed mice by 26.9 % (p < 0.01) and 16.2% (p < 0.05), respectively. However, in the other test performed at 15±0.5℃ using 31 day-fed mice, Vigilor failed to increase the exhaustion time significantly (at p< 0.05), while Vital showed antifatigue effect by increasing the swimming time by 29.9% (p<0.01). Neither of Vital nor Vigilor exerted antifatigue effects in a swim test carried out on day 14 after the initiation of feeding. These results suggest that Vital and Vigilor exhert antifatigue effets when administered for a sufficient period of time by enhancing the health of the host animals.

민들레 잎과 뿌리 분말을 첨가한 설기떡의 품질 특성

유경미,김세희,장정화,황인경,김경임,김성수,김영찬 한국조리과학회 2005 한국식품조리과학회지 Vol.21 No.1

In order to develop a dandelion (Taraxacum officinale) with natural food applications, the effects of dandelion leaves and roots powder content on the physical, textural and sensory properties of sulggidduk were examined. Dandelion powders of leaves and roots at 0, 1, 2 and 3% were added to the dandelion sulgidduk. In the dandelion roots powder in sulgidduk, the color intensity of L values and the values and moisture content decreased however, the sensory color intensity, dandelion flavor and overall acceptability increased with increasing the dandelion powder content. The sensory overall acceptability indicated the dandelion roots powder content at 3% had the highest overall and flavor scores. As the dandelion leaves content was increased, the moisture contents, lightness, adhesiveness and cohesiveness of sulggidduk decreased, while the sensory color intensity, sensory hardness, hardness of texture properties and dandelion flavor increased. The addition at 1% of the dandelion leaves powder content with the dandelion sulggidduk and the addition at 3% of the dandelion roots powder content with the dandelion sulggidduk showed the highest overall acceptability.

임신 중 발견된 대망 종괴 1례

조인숙,김태의,김정식,이해혁,이권해,김희경,남계현 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

A case of omental mass during Pregnancy Omental cyst is a rare lesion and occur primarily during childhood and young adulthood. When encountered, most of them are benign and intraabdominal masses. It shows a large mass but not palpable and often asymptomatic. The precise diagnosis is made by most commonly at surgery or during pathologic examination. So, we report this case with brief review of literatures.

결혼이주여성과 한국여성의 양육 스트레스 비교

김혜경 ( Hae Kyeong Kim ),이은희 ( Eun Hee Lee ) 서울대학교 간호과학연구소 2014 간호학의 지평 Vol.11 No.2

Purpose: The purpose of this study was to compare parenting stress between married migrant women and Korean women. Methods: Subjects were 68 married migrant women and 70 Korean women raising children aged seven years or younger, living in three different cities in Gangwon Do. To measure parenting stress, we used Kim`s (1997) questionnaire that had been modified from Richard & Abidin`s (1990) Parenting Stress Index (PSI). Results: There were significant differences between the two groups in age, academic credentials, job, monthly income, and achievement of maternal role. No statistically significant differences were found for parenting stress scores (p<.355), but there was a significant difference in the child characteristics of parenting stress (p<.007) between the two groups. There were no differences in the demographic variables influencing parenting stress between the two groups. Conclusion: The development of multi-cultural parenting and family support programs should consider the nationality and marital satisfaction of the family.

민들레 추출액 농도에 따른 민들레 코팅쌀밥의 품질에 관한 연구

유경미,이연경,김세희,황인경,이부용,김성수,홍희도,김영찬 한국조리과학회 2005 한국식품조리과학회지 Vol.21 No.1

Washed rice was coated by spraying aqueous dandelion (Taraxacum officinale) extracts at 20, 30, 40 'Brix and dried at room temperature. The coating procedure was conducted 5 mL/min for 10min. Property changes in the dandelion coated rice and un-coated cooked rice were observed during 2 days of storage. Increasing the coating concentration was associated with lower color values (L, a value) and moisture contents. Sensory and texture properties generally decreased in the cooked rice coated with dandelion more than the control (non-coated rice). But, D-20(20 °Brix of the dandelion concentration) resulted in better textural properties and s ensnry scores for hardness and overall acceptability in cooked rice. Compared to the control, the washed rice roated with 20 °Brix for 0 and 2 days showed better quality in sensory activities, a lower gel consistency and better textural activities. It was concluded that the optimum coating ration of rice and added dandelion extract for cooking were 20 °Brix and 5% respectively, in proportion to the total weight of raw rice.