자폐아동의 기본운동교육프로그램 참가가 지각운동능력발달에 미치는 영향

이창섭,이명휘,현광석,이창규,조병준 한국특수체육학회 2003 한국특수체육학회지 Vol.11 No.1

The purpose of this study was to examine how the program of basic movement can influence and change the capability of perceptive movement among the children with autism. Four subjects (age3-5) participated in the specially designed program, three times a week for four weeks. For the purpose of this study, Oseretsky's Motor Development Test and PMDT(perception-Movement development Diagnosis Test) were used. The results were as follows; First, the upper limb performance of the children with autism showed significant changes by the movement education program. Second, along with the development of upper limb performance, the motor development index of the children with autism showed significant changes. Third, the Oseretsky spectrum of movement, of the children with autism responded to the order of mono-movement capability, hand-movement and co-operative movement. Fourth, the movement education program was more effective for the children with autism than for the retarded children in view of motor development capability. Fifth, the movement education program was more effective for the child with autism of multi-movement characteristics.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

Ethylenediamine-N,N'-di-α-Butyric Acid의 로디움(Ⅲ) 착물

전무진,한창윤,박장우,최승락,박광하 연세대학교 자연과학연구소 1985 學術論文集 Vol.15 No.-

네자리 리간드인 ethylenediamine--N,N'-di-α-butyric acid(eddb)의 디클로로 로디움(Ⅲ)착물을 합성하고 크로마토그래피법으로 분리하였다. Eddb리간드가 로디움(Ⅲ) 이온에 배위될 때 s-cis와 uns-cis기하 이성체가 형성됨이 관찰되었다. 합성된 착물의 구조는 적외선 분광분석법, 핵자기 공명 및 흡수 스펙트럼으로 확인되었다. Dichloro rhodium(Ⅲ) complex of a flexible tetradentate ligand of ethylenediamine-N,N'-di-α-butyric acid(eddb) has been prepared and separated by the chromatographic method. S-cis and uns-cis geometric isomers have been yielded during the preparation of complex. IR, PMR and electronic absorption spectra have been used to characterize the complex.

珪酸마그네슘의 合成條件에 關한 硏究

전우정,신화우,최광식,안세민,이광표,장영수 원광대학교 식품약품안전성연구소 1993 食品藥品安全性硏究 Vol.6 No.-

Magesium twisilicate is mainly uaed as a nonsytemic antacid andabsrbent. Magnesium trisilicate when teeated with anacid sxuh as diluted hydrochloric acid in gastric juice decomposes to form Magnesium chloride and colloidal Silicates. 2MgO·3SiO_2 + 4Hcl - 2MgCl_2 + H_4Si_3O_8 (or 3SiO_2 + 2H_2O) Colloidal mixture The resultng colloidal silicates can protect ahe ulcer frdm further acid and peptic attack and possibly adsorb the pepsin. It is well known that yield of Magnesium trisilcate produced is greatly affected by the Synthesis condition such as the reactant concentration, reaction temperature and moleatio of reactant solutions as well as by the emperature at which the precipitate is dried and the temperature of washing water, etc. The purpose of this study is to investigate the optimum synthesis conditions of Magnesium trisilicate. A randomized complete block design suggested by G.E.P. Bdx and K.B. Wagnesium sulfate solution with Sodium silicate solution in this study. It was found that optimal synthesis conditidns were: Reaction temperature range : 57-90 ℃. Concentration range of reactants (Sodium silicate and Magnesium sulfate) : 19.1-29% molar ratio of the reactants. [Sodium silicate]/[Magnesium sulfate]: 1.47-1.80. temperature range of washing water: 45-48℃ and drying temperature range: 65-82℃ The antacidic activity of five Magnesium trisilicate samples which shows the maximum antacidic efficacy was tested by pharmacopeia acid consuming capacity test. The five Magnesium trisilicate samples were samples were identified by chemical analysis.

댄스스포츠 참여가 청각장애인의 사회,정서 발달에 미치는 영향

이창규,현광석,조병준,김영표,김용진 한국특수체육학회 2002 한국특수체육학회지 Vol.10 No.2

The purpose of this study was to find out the effects of participation in dance sport programs on development of social-emotional behaviors of deaf students. The subjects were 20 deaf students of middle and high school for special education, and the subjects were randomly devided into participant group(n=10) and non-participants group(n=10). Meadow/Kendall social-emotional asessment inventory for the deaf students(1980) by Kim(1990) were administered by specialized teachers of the students. The statistical procedures used to analysed the hypotheses were ANCOVAs. The major findings of this study were that deaf students who regularly participated in dance sport activities had significantly higher level of the development of social adaptation, self-consciousness, and emotional adaptation rather than non-participants. It could be concluded in this study that sport activities had significant effects on the development of social-emotional behaviors of deaf students.

학생생활 질 개선에 관한 연구 : 충남대학생들의 LIFE STYLE 조사연구 Life Style of Students in Chungnam National University

서창원,전광희,김교헌,정용길,차상철,양병창 충남대학교 1993 學生生活硏究 Vol.20 No.-

콩코드 납축전지의 SOC 추정

전창완,채광석,임준규,오명섭,박명신 순천향대학교 부설 산업기술연구소 2004 순천향 산업기술연구소논문집 Vol.10 No.1

Nowadays many battery-based systems like electric vehicle have appeared. As a result efficient battery management becomes important. In this paper, state-of-charge (SOC) estimation of a Concode lead acid battery is discussed. The SOC estimation problem plays an important role in battery management system(BMS). In this paper, an SOC table is established by many charge and discharge experiments. This table can be used to development advanced SOC estimation algorithms.

막결합 간헐포기공정에서의 SRT와 C/N비에 따른 공정 자동제어

이준명 ( Jun-myeong Lee ),최창규 ( Chang-kyoo Choi ),이광호 ( Kwang-ho Lee ) 한국환경기술학회 2011 한국환경기술학회지 Vol.12 No.2

본 연구에서는 막결합 간헐포기공정에서의 SRT와 C/N비 변화시에 하나의 cycle내 ORP와 DO곡선의 변화와 NH₄⁺-N과 NO₃^--N 농도를 비교함으로써 막결합 간헐포기공정의 자동제어를 위한 적정 운영인자에 대한 가능성을 검토하고자 하였다. SRT 20day, 30day, 40day의 경우, 호기조건의 질산화 종료시점은 DO보다는 ORP 곡선과 밀접한 연관성을 가지고 있었으며, 무산소조건의 탈질 종료시점은 나타나지 않았다. C/N비 4.5, 7, 10에서의 질산화 종료시점 또한 ORP 굴곡점과 같은 시간에 나타났으며, 탈질 종료시점은 C/N비 10에서만 나타났는데 탈질종료시점과 같은 시점에 ORP의 경우 굴곡점이 나타난 반면 DO 곡선에는 변화가 없어 질산화종료시점과 마찬가지로 탈질종료시점도 ORP 곡선과 밀접한 연관성을 갖고 있었다. 따라서, 막결합 간헐포기공정의 자동제어는 DO 보다는 ORP 곡선을 이용하는 것이 적절할 것으로 판단된다. The purpose of this study was to inquire into the proper factor for the auto control of the process, as it compared ORP and DO curves with the variation of NH₄⁺-N and NO₃^--N concentration in a cycle. In the results to be operated in SRT 20day, 30day and 40day, the nitrification ending point coincided with ORP bending point in the aerobic state, however, the denitrification ending point wasn`t revealed in the anaerobic state. In the results to be operated in C/N 4.5, 7 and 10, the nitrification ending point appeared with ORP bending point at the same time. Also, the denitrification ending point presented at C/N ratio 10, then ORP bending point coincided with the ending point, on the other hand, DO curve wasn`t changed. Therefore, the ORP curve was more appropriate factor than DO for the auto control of IAMBR.

서울대학교 치과병원 장애인진료실의 외래환자마취 실태 분석

박창주,정준민,김현정,장기택,이상훈,염광원 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.1

치과적 장애인이란 치과진료 시 치과의사에게 자발적인 협조가 힘든 사람을 의미한다. 본 연구는 서울대학 치과병원 장애인진료실에서 치료받은 치과적 장애인 환자들의 임상진료 실태를 마취과적으로 분석하고 향후 장애인 치과치료에 대한지침 을 마련하고자 하였다. 1999년 1월부터 2002년 10월까지 서울대학교 치과병원 장애인진료실에 내원한 장애인 환자들을 대상으로 조사한 결과, 총89명의 환자들에게 93건의 치과진료가 시행되었다. 환자의 대다수는 정신지체였고 전신마취 하 보존치료를 받았다. 주로 마취유도제는 thiopental, 근이완제는 vecuronium을 이용하였으며 산소, 아산화질소, enflurane을 함께 흡입시켜 마취를 유지하였다. 총 마취지속시간과 회복실 체류시간은 각각 164.4±57.2 분과 106.2±50.5 분이었고 회복 과정에서 심각한 합병증은 관찰되지 않았다. 본 연구는 외래환자마취에 기반한 서울대학교 치과병원 장애인진료실의 치료방침에 따라 특별한 문제없이 성공적인 마취가 가능하였음을 보여 주었다. 또한 증가하는 장애인 치과치료에 대한 수요를 충족시키기 위해서 적절한 시설과 인력을 갖춘 보다 많은 외래환자마취 센터의 필요성도 제시한다고 할 수 있다. Dentally disabled person means one who have difficulty in cooperating voluntarily with a dentist for routine dental care. Seoul National University Dental Hospital (SNUDH) Dental Clinic for Disabled has worked for them under outpatient anesthesia concept. The aim of this study was to determine the anesthetic characteristics of the patients attending for dental treatment at SNUDH Dental Clinic for Disabled in order to establish better future treatment plans. The data were drawn from the patients who visited SNUDH Dental Clinic for Disabled from January 1999 to October 2002. Total 93 dental treatments for 83 patients were enrolled in this study. Most patients had mental retardation and the conservative treatments were carried out under general anesthesia. Thiopental and vecuronium were mostly used for induction agent and neuromuscular blocker, respectively. Enflurane, with oxygen and nitrous oxide, was mostly used to maintain the anesthesia. Mean total anesthetic time was 164.4±57.2 minutes and mean duration at the post-anesthetic care unit was 106.2±50.5 min. Serious postoperative complications were not observed. These results showed our successful anesthetic outcomes without any severe side effect or complication and the needs of more outpatient centers for dental care for disabled.

Silicone rubber 멤브레인을 이용한 압저항형 저차압센서의 개발

서창택,공성수,심준환,고광락,서현미,김영진,설철규,신장규,이종현 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

A 4-beam piezoresistive differential pressure sensor using a silicone rubber membrane has been fabricated on the selectively diffused (100)-oriented n/n^(+)/n silicon substrates by an unique silicon micromachining technique using porous silicon etching. The width, length, and thickness of the beam is 120 μn, 600 μm, and 6 μm, respectively, and the thickness of the silicone rubber membrane was 36 gm. By the use of four-beam structure, the mechanical strength of the differential pressure sensor can be highly improved due to smaller shear stress. And the lower sensitivity of the sensor can be simply solved by combining two output signals of half-bridge. The effectiveness of the sensor is confirmed through an experiment and FEM simulation in which the differential pressure sensor is characterized.