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      • 경량 고강도 Mg-Zn계합금의 조직과 내식성에 관한 연구

        안효준,남태현,임수근,안인섭,허보영,김기원 慶尙大學校 1995 論文集 Vol.34 No.1

        The purpose in this study is to develope of high strength and corrosion reistant Mg-Zn system alloys by controlling microstructures and by adding of Cu elements. To produce optimum tesile strength,it is imperative to obtain effective grain refinment during casting. Optimal condition for grain size refining effect was obtained at the minmum composotion of 2wt% Cu or 1.5wt%So addition to Mg-6wt%Zn alloy.Age hardening behavior was experimented at the optimal compositions of the Mg-6wt%Zn, Mg-6wt%Zn-2wt%Cu and Mg-6wt%Zn-1.5wt%Si. The hardeness increment due to age hardening was at the Mg-Zn-Si alloy system. The improvement of corrosion resistanece by the addition with Cu is related to and increasing Zn/Cu ration in the intermatallic particles in the Mg-Zn system.Further improvements obtained by T6 treatment are related to the properties of the Mg-Zn phase,whih acts as a corrosion barrier by precipitating along the grainboundaries.Filiform corrosion observed soon after pit initiation and cellular form of pit propagation later in chloride media are explained in terms of solid solution matrix structure and the properties of air formed oxide.The information obtained from the fundamental research work is utilized in suggesting ways of improving the corrosion resistance of commercial AZ91.

      • SCOPUSSCIEKCI등재

        Transthyretin의 Glutathione 자동산화 촉진작용

        박종근,정신,김재휴,김수한,강삼석,이제혁,안봉환 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.8

        When reduced glutathione(GSH) was incubated at neutral pH and at 37°, its concentration decreased slowly with formation of oxidized glutathione(GSSG). Autooxidation of GSH was accelerated by Cu^(2+) and Hg^(2+), but not by other common mono-, di-, and tri-valent cations. Transthyretin was found to stimulate autooxidation of GSH in the presence or absence of Cu^(2+) and Hg^(2+). EDTA inhibited perfectly the autooxidation of GSH regardless of the presence of transthyretin. The stimulating activity of transthyretin was maximal at pH 7.0, declining progressively with increase or decrease of pH from 7.0. Sulfhydryl-blocking agents such as p-hydroxymercuribenzoic acid and Nethylmaleimide markedly inhibited the stimulating activity of transthyretin. Transthyretin stimulated autooxidation of other sulfhydryl compounds such as clithiothreitol and cysteine. However, it did not show a significant effect on autooxidation of sulfhydryl group of egg albumin and eye lens proteins. And transthyretin did not cause any oxidative change to thyroxine(T₄), 3, 5, 3Ltri iodo thyronine(T₃) and 3, 3: 5~triiodothpnine(rT₃) bound to it in the presence of GSH and Cu^(2+). The above results suggest that transthyretin may play a role in regulation of oxidized status of sulfhydryl groups in blood plasma and cerebrospinal fluid

      • 퍼지모델링을 이용한 저속비대선의 선미형상 주요치수 결정

        김수영,김현철,정성재,하문근,안당,신수철 釜山大學校生産技術硏究所 1998 生産技術硏究所論文集 Vol.55 No.-

        본 연구에서는 유전자 알고리즘을 적용한 퍼지모델링 기법을 이용하여 저속비대선에서 선미형상의 주요치수를 결정하고, 이를 실적선과 비교하였다. . This paper presents a method that determines the stern profile dimensions for full, slow-speed ship using fuzzy modeling, applied the genetic algorithm and compares with the database of ships

      • SCOPUSSCIEKCI등재

        안면 비대칭의 평가를 위한 기준에 관한 정보 두부 방사선 계측학적 연구

        백선호,안병근,김선해,손홍범,한호진,강수만 대한치과교정학회 1993 대한치과교정학회지 Vol.23 No.1

        This study was undertaken to investigate the middle having the least difference between the right and left structures among the lines that had been used in the study of the craniomaxillofacial asymmetry. The sample of this study consisted of twenty six Korean girls(average 18.9 years old) having normal facial appearance and occlusion. On the frontal cephalometric films of the sample, we divided the whole craniomaxillifacial area into four portions, i.e., cranial, upper facial, lower facial, and dental portion. So, we have found the midlines having the least difference in the whole craniomaxillofacial area itself, and in the each divided four portions, furtherly in the other portions from aimed portion. The findings were as follow : 1. In the whole craniomaxillofacial area, the connecting line between crista galli and anterior nasal spine and the perpendicular bisecting line between right and left foramen rotundrums were suitable for the midline. 2. In the cranial portion, established all six lines were suitable for midlines. In the other portions, the perpendicular bisection line between both condylion, the line passing the contact point between right and left mandibular central insisiors among the perpendicular lines between right and left mandibular central incisial tips were suitable midlines for evaluating the asymmetry of cranial portion. 3. In the upper facial portion, the perpendicular bisecting line between right and left zygions was the most suitable midline. In the other portions, the line between the crista galli and the most superior point of the odontoid process, the perpendicular bisecting line between right and left gonions, the perpendicular bisecting line between right and left condylions, and perpendicular bisecting line between right and left foramens rotundum were suitable midlines for evaluating the asymmetry of the upper facial portion. 4. In the dental portion, the perpendicular bisecting lines between right and left buccal cusps of both maxillary first molars and between right and left mandibular first molars were suitable midlines. In the other portions, the perpendicular bisecting line between right and left landmarks crossing the lesser wing of the connecting line between crista galli and prosthion were suitable midlines for evaluating the asymmetry of dental portion. 5. In the lower facial portion, the perpendicular bisecting lines between right and left condylions and between right and left gonions were suitable midlines. In the other portions, the line between the crista galli and anterior nasal spine, the perpendicular bisecting line between right and left foramen rotundums, and the perpendicular bisecting lines between right and left buccal cusps of both mandibular first molars and between right and left maxillary first molars were suitable midlines for evaluating the asymmetry of the lower facial portion.

      • KCI등재

        Correlation between Overactive Bladder Syndrome and Obsessive Compulsive Disorder in Women

        Keun-Soo Ahn,Hyun-Pyo Hong,권혁중,Ah-Leum Ahn,Eun-Jung Oh,최재경,조동영 대한가정의학회 2016 Korean Journal of Family Medicine Vol.37 No.1

        Background: Overactive bladder syndrome is characterized by urinary urgency, usually accompanied by Frequent urination and nocturia, with or without urgent urinary incontinence. There must be the absence of causative infection or pathological conditions. Overactive bladder syndrome is related to mental disorders, particularly depression and anxiety. However, obsessive-compulsive symptoms are investigated much less frequently. The purpose of the present study was thus to assess obsessive-compulsive symptoms in overactive bladder syndrome patients. Methods: Fifty-seven women patients with overactive bladder syndrome and fifty-seven women without it (age matched control group) were prospectively enrolled. They completed the overactive bladder syndrome-validated 8-question screener and the Korean version of the Maudsley Obsessional-Compulsive Inventory Questionnaire at the same time they visited the clinic. Patients were compared with controls on the Korean version of the Maudsley Obsessional-Compulsive Inventory Questionnaire and its checking, tidiness, doubting, and fear of contamination components. Results: Patients showed more obsessive traits than controls on the Korean version of the Maudsley Obsessional- Compulsive Inventory Questionnaire total score (P=0.006) and on the checking subscale (P=0.001). Odds ratio for the overactive bladder syndrome group’s obsessive-compulsive symptoms traits (score≥14) was 5.47 (P=0.001). The Korean version of the Maudsley Obsessional-Compulsive Inventory Questionnaire total score was associated with the overactive bladder syndrome-validated 8-question screener score in patients (P=0.03). Conclusion: Obsessive-compulsive symptoms may constitute an important aspect of the psychiatric profile of overactive bladder syndrome patients. The severity of obsessive-compulsive symptoms seems to be related to the degree of the overactive bladder syndrome severity. Clinicians may consider screening women with overactive bladder syndrome for obsessive-compulsive symptoms.

      • KCI등재후보
      • SCIESCOPUS

        Impact of preoperative endoscopic cholangiography and biliary drainage in Ampulla of Vater cancer

        Ahn, Keun Soo,Kang, Koo Jeong,Kim, Yong Hoon,Lee, Yoon Suk,Cho, Gwang Bum,Kim, Tae-Seok,Lee, Jung Woo Elsevier 2018 Surgical oncology Vol.27 No.1

        <P><B>Abstract</B></P> <P><B>Background</B></P> <P>Ampulla of Vater (AOV) carcinoma is a rare malignancy but has a relatively good prognosis. The aims of this study were to determine the clinicopathologic factors associated with survival and disease recurrence in patients with AOV cancer, focusing on the impact of preoperative endoscopic retrograde cholangiopancreatography (ERCP) and type of biliary drainage (endoscopic retrograde biliary drainage [ERBD] or percutaneous transhepatic biliary drainage [PTBD]).</P> <P><B>Methods</B></P> <P>We retrospectively reviewed the medical records of 80 patients who underwent curative resection for AOV cancer at a single institution between 1995 and 2015. The clinicopathologic factors associated with survival and disease recurrence were analyzed using univariate and multivariable tests.</P> <P><B>Results</B></P> <P>The 5-year disease-free and overall actuarial survival rates were 39.3% and 51.3%, respectively. Moderate or poor differentiation, preoperative ERCP, advanced T stage, lymph node metastases, advanced stage and lymphovascular invasion were associated with disease-free survival in univariate analyses. The prognosis was worse in patients who underwent ERBD than in patients who underwent PTBD or no biliary drainage. Multivariable analysis showed that advanced AJCC stage and preoperative ERCP were independent risk factors for recurrence. Patient who underwent preoperative ERCP had a significantly higher rate of early distant metastasis within 1 year, especially in patients with early stage AOV cancer.</P> <P><B>Conclusions</B></P> <P>Preoperative ERCP was an independent risk factor for postoperative recurrence in patients with AOV cancer, and is characterized by early distant metastasis in early stage cancer. Therefore, unnecessary ERCP should be avoided in patients with AOV cancer. If biliary drainage is necessary, PTBD may be preferred to ERBD in AOV cancer.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Preoperative ERCP is a risk factor for poor long term outcome in AOV cancer. </LI> <LI> ERCP is related with early distant metastasis in early stage AOV cancer. </LI> <LI> PTBD is preferred to ERBD for preoperative biliary drainage in AOV cancer. </LI> </UL> </P>

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