디지털 위서 통신 채널의 비선형성 보상을 위한 신경회로망 등화기의 설계 및 평가

윤병문,김정희,임영선,진근식,신요안 崇實大學校 生産技術硏究所 1995 論文集 Vol.25 No.2

A digital satellite communication channel has a strong nonlinearity with memory due to saturation characteristics of the high power amplifier in the satellite and transmitter/receiver filters used in the overall system, and can be well modelled by a nonlinear Volterra series. In this paper, we design and evaluate neural network based adaptive equalizers for compensation of nonlinearities in digital satellite communication channels. We consider CMLP (complex multi-layered perception). CRBFN (complex radial basis function network) and complex ρth order Volterra filter as equalizers, and evaluate their performances in terms of symbol error rate under various noise conditions. In particular, a complex hybrid learning algorithm of k-means clustering and LMS (least mean squares) algorithm is proposed for the CRBFN. Computer simulation results show good performance for all the equalizers considered

인슐린 비의존성 당뇨병에 동반된 심상성 천포창 1 례

이상준,박진용,임태형,윤영호,권순대,남창욱,허규찬,박근용,구본식,김상표,장종억 啓明大學校 醫科大學 1997 계명의대학술지 Vol.16 No.3

저자들은 인슐린 비의존형 당뇨병 환자에서 통증성 구강내 미란 및 전신성 수포성 미란을 동반한 심상성 천포창 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Various skin conditions such as diabetic dermopathy, necrobiosis lipoidica diabeticorum, bullosis diabeticorum, granuloma annulare occur frequently in diabetes, although common lesions may be associated by chance. Pemphigus vulgaris(PV) is a blistering skin disease seen predominantly in elderly patients. This disorder is characterized by the loss of cohesion between epidermal cells with the resultant formation of intraepidermal blisters. These blisters rupture easily, leaving denuded areases that may crust and enlarge peripherally. In half or more of patients, lesions begin in the mouth: approximately 90% of patients have oromucosal involvement at some time during the course of their disease. But the relationship of this disorder with diabetes is not clear. We experienced a case of pemphigus vulgaris associated with NIDDM in 67 years old woman who was admitted due to painful oral ulcer and control of blood glucose, so we present this case with a review of literatures.

심방조동과 특발성 심실빈맥 환자의 의식소실을 위해 사용한 Propofol 에 의한 정상 동성리듬으로의 전환

김태정,이춘수,이홍식,차영덕,정종권,임현경,이성근,한정욱,허이희 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.42 No.2

前腕部 經穴 取穴에서 骨度分寸法과 一夫法의 比較 硏究

박히준,채윤병,차웅석,박종배,이혜정,이향숙,인창식,고형균,김수영,최일환,김강식,문정배,배기태,유경환,육근영,정병주,손인철,임사비나 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Background : The cun measurement System, an essential and convenient method in locating acupoints, has been widely used in the practice of acupuncture. However, traditional cun measurement has been criticized for its lack of reliability. Objectives : The purposes of this study are to determine if one cun measured by the directional methods have a consistency with that of proportional methods and to investigate which factors are related with these differences, especially in forearm. Methods : The distance between the elbow crease and the wrist crease of forearm was compared to a reference value of one cun obtained by the directional method. In this method, one cun is one third of the distance between index finger and Small finger of a subject, measured at proximal interphalangeal joint. In addition, to investigate the factors influencing the differences between these two methods, we measured the height and body weight and calculated body mass index (BMI). Finally we analyzed the factors correlated with these lengths by linear regression test. Results : The results showed that one cun obtained by the directional methods were significantly different from one cun by the proportional methods in forearm. It was demonstrated that the length acquired with the directional method was more correlated with body weight and body mass index, while the length obtained by the proportional method was more correlated with the height.

Enhancement of Anti-MRSA (Methicillin Resistant Staphylococcus aureus) Activity by Fungal Fermentaion of Ecklonia cava Residue

Keun-Sik LIM,Sung-Hwan EOM,Tae-Young KIM,Hyeon-Ah CHO,Won SONG,Young-Mog KIM 한국생물공학회 2009 한국생물공학회 학술대회 Vol.2009 No.10

'95년 한국동해에서의 수온전선과 와동류의 구조 및 특성조사

임근식(Keun-Sik Lim),왕갑식(Kap-Sik Wang),윤재열(Jae-Yul Yun),김기철(Ki-Cheol Kim),김영규(Young-Gyu Kim),김구(Kuh Kim) 한국해양공학회 1996 韓國海洋工學會誌 Vol.10 No.2

The characteristics and fluctuations of structures and spatial distributions of thermal fronts and warm eddy in the Southeastern part of the East sea are discussed based on the data collected by the Naval Academy, Korea during Feb. 6-9, May 9-19 and Oct. 12-18, 1995. The thermal fronts existed very often at the sea off the Pohang-Ulsan. The generation of the thermal front is related with the development of the North Korea Cold Current. The warm eddy is located in the central part of the Ulleung basin where the local depth exceeds 1500m. This warm eddy is quasi-ellipse, having a diameter of approximately 150㎞. This large anticyclonic eddy is a major contributor to mass transport in the northern part of the East Sea. It is evident that knowledge of warm eddy is important in understanding the circulation in the western part of the East Sea.

Flavobacterium chungbukense sp. nov., isolated from soil.

Lim, Chae-Sung,Oh, Yong-Sik,Lee, Jae-Kwan,Park, A-Rum,Yoo, Jae-Soo,Rhee, Sung-Keun,Roh, Dong-Hyun Society for General Microbiology 2011 International journal of systematic and evolutiona Vol.61 No.11

<P>A yellow-pigmented, Gram-staining-negative, non-motile, strictly aerobic and rod-shaped bacterium, designated CS100(T), was isolated from soil in Chungbuk, Korea. Phylogenetic analysis and comparative studies based on the 16S rRNA gene sequence showed that strain CS100(T) belonged to the genus Flavobacterium in the family Flavobacteriaceae. Strain CS100(T) showed the highest sequence similarities to Flavobacterium glaciei JCM 13953(T) (97.6 %) and Flavobacterium johnsoniae KACC 11410(T) (97.1 %). Sequence similarity to other members of the genus Flavobacterium was 91.5-97.0 %. Growth occurred at 4-30 C, at pH 5.0-9.0 and in the presence of 0-2 % (w/v) NaCl. Flexirubin-type pigments were produced. Menaquinone-6 (MK-6) was the major respiratory quinone and the major fatty acids were iso-C(15 : 0) (17.3 %), summed feature 3 (comprising iso-C(15 : 0) 2-OH and/or C(16 : 1)ω7c, 15.5 %) and C(16 : 0) (11.8 %). The DNA G+C content was 36.4 mol%. Strain CS100(T) hydrolysed skimmed milk and gelatin, but not chitin or pectin, and showed oxidase and catalase activities. DNA-DNA relatedness was 3.0 % with F. glaciei JCM 13953(T) and 11.5 % with F. johnsoniae KACC 11410(T). On the basis of the evidence from this study, strain CS100(T) represents a novel species of the genus Flavobacterium, for which the name Flavobacterium chungbukense sp. nov. is proposed. The type strain is CS100(T) ( = KACC 15048(T) = JCM 17386(T)).</P>

Water-jacket reactor cavity cooling system concept to mitigate severe accident consequence of high temperature gas-cooled reactor

Lim, Hong Sik,Tak, Nam-il,Lee, Sung Nam,Jo, Chang Keun Elsevier 2018 Nuclear engineering and design Vol.340 No.-

<P><B>Abstract</B></P> <P>The High Temperature Gas-Cooled Reactor (HTGR), as a Gen-IV reactor, adopts a Reactor Cavity Cooling System (RCCS) to remove core decay heat after a reactor trip. During a postulated accident such as a pipe break in the reactor coolant system, the core decay heat can be properly removed by a RCCS to ensure the integrity of the fuel, reactor pressure vessel (RPV), and concrete silo. In this study we are more interested in the impact of a failure beyond that of the design basis of the RCCS functions, particularly the case in which natural convection of external air is not established. Such a case could happen when a chimney is collapsed by an external event. Against a severe disaster in which air convection is completely lost, a mixed air-water RCCS concept having a water-jacket system is suggested in order to mitigate the significant overheating of the RPV. In order to quantify the effectiveness of the water-jacket RCCS functions, the Depressurized Conduction Cooldown event (DCC) of a HTGR system with a thermal power of 350 MW is analyzed using the GAMMA+ system transient analysis code. As the RCCS air-cooling function is impaired, the water-jacket system increases its role to take part in the heat removal. From the analysis results of a DCC event with complete failure of the RCCS air-cooling, it is confirmed that, compared to the case without the water-jacket system, the maximum temperature of the reactor vessel can be reduced by about 400 °C thus ensuring its integrity. Therefore, the water-jacket system can be utilized as a backup system to mitigate the consequences of a severe accident such as the collapse of the chimney of the RCCS.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A water-jacket RCCS concept was suggested for HTGR decay heat removal. </LI> <LI> This is applied to the conventional HTGR with a thermal power of 350 MWth. </LI> <LI> A DCC event was analyzed using the GAMMA+ analysis code for its effectiveness. </LI> </UL> </P>

The immunogenicity and protection effect of an inactivated coxsackievirus A6, A10, and A16 vaccine against hand, foot, and mouth disease

Lim, Heeji,In, Hyun Ju,Lee, Jung-Ah,Sik Yoo, Jung,Lee, Sang-Won,Chung, Gyung Tae,Choi, Young Ki,Chung, Jae Keun,Cho, Sun Ju,Lee, June-Woo Elsevier 2018 Vaccine Vol.36 No.24

<P><B>Abstract</B></P> <P>Coxsackievirus belongs to the <I>Enterovirus</I> genus of the <I>Picornaviridae</I> family and is one of the major pathogens associated with human hand, foot, and mouth disease (HFMD). Historically, outbreaks of HFMD have mainly been caused by enterovirus 71 and coxsackievirus A16. Recently, coxsackieviruses A6 and A10 have been associated with increased occurrences of sporadic HFMD cases and outbreak events globally. In this study, the immunogenicity of coxsackieviruses A6, A10, and A16 (CA6, CA10, and CA16), which were inactivated by formalin or β-propiolactone (BPL) under different conditions, was evaluated as multivalent vaccine candidates. CA6 induced similar immune responses with both inactivation methods, and the immune efficacy of CA10 and CA16 was better following inactivation with BPL than with formalin. There was no sufficient cross-reactivity or cross-protectivity against heterologous strains in groups vaccinated with the BPL-inactivated (BI) monovalent vaccine. Sufficient neutralizing antibody and cell-mediated immune responses were induced in the BI-trivalent vaccinated group. These findings suggest that BI-CA6, CA10, and CA16 are potential multivalent vaccine candidates and that a multivalent vaccine is needed to control HFMD. The coxsackievirus multivalent vaccine could be useful for the development of effective HFMD vaccines.</P>

무수프탈산을 취급하는 근로자들의 알레르기 질환 유병 실태

임현술,김수근,김기식 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.4

Phthalic anhydride(PA) is widely used in the production of alkyd and unsaturated polyester resins. It has been reported that some workers exposed to PA have developed dermatitis, rhinitis and asthma. The authors intended to investigate the prevalence of PA induced allergic diseases and to develop preventive measures of occupational diseases. Forty-five male workers from PA production and handling were selected as an exposure group. Forty-four male workers not handling PA at tie same factory were chosen as a reference group. A symptom questionnaire, doctor's examination, eosinophil count, serum-total IgE and PA-specific IgE were done on the subjects. There were no significant differences in age, educational level. tenure or smoking habits between groups. Most clinical symptoms were significantly more frequent among the exposure group than the reference group: sneezing(62.2%), rhinorrhea(57.8%), nasal stuffiness(53.3%), coughing(44.4%) and nasal itching(35.6%) were the major symptoms among the exposure group(p<0.01, p<0.05). There were no significant differences in eosinophil count and serum-total IgE between groups but the mean level in PA-specific IgE, in the exposure group, was statistically significantly higher than the reference group(p<0.01). Abnormal rates of eosinophil count, serum-total IgE and PA-specific IgE were not significantly different from each other. The prevalence rate was 68.9%(31 cases) for allergic rhinitis in the exposure group, statistically significantly higher than the reference group(p<0.01). The prevalence rate was 6.7%(3 cases) for bronchial asthma and contact dermatitis in the exposure group, not more statistically significant than the reference group. In the exposure group, the prevalence rate for age, educational level, tenure, smoking habits and use of protective devices are not statistically significant. In PA specific IgE, sensitivity is 10.8%, specificity is 100.0%, positive predictability is 100.0% and negative predictability is 61.2% when criteria point is 3.5 KU/ιor above. As a result, it was recognized that the exposure group had a high prevalence of PA induced allergic rhinitis. Also, in diagnosis of PA induced allergic diseases, medical histories and specific symptoms were the most important where as eosinophil count, serum-total IgE are the only indirect informations. PA-specific IgE has been needed to evaluate the meanings more.