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Alteration of Mitotic Checkpoint Gene hMAD1 in Primary Hepatocellular Carcinomas
박능화,신정우,정영화,이영상,서동진,류명수,( Kenneth H. Buetow ) 대한간학회 2005 Clinical and Molecular Hepatology(대한간학회지) Vol.11 No.3(S)
Background: The mitotic checkpoint functions to block the anaphase entry until each of every condensed chromosome has successfully attached to the spindle microtubules. Aneuploidy is commonly observed in many cancers including hepatocellular carcinoma (HC
Alteration of Fragile Histidine Triad (FHIT) Gene in Human Primary Hepatocellular Carcinomas
박능화,신정우,정영화,이영상,서동진,류명수,( Kenneth H. Buetow ) 대한간학회 2005 Clinical and Molecular Hepatology(대한간학회지) Vol.11 No.3(S)
Background: The fragile histidine triad (FHIT) gene located at chromosome 3p14.2, is a candidate tumor suppressor gene often involved in various tumors. The role of FHIT in hepatocarcinogenesis has not been fully investigated. Material and Methods: We exa
The Role of Fragile Histidine Triad As Tumor Suppressor in Pathogenesis of Hepatocellular Carcinoma
송일한 ( Song Il Han ),신정은 ( Sin Jeong Eun ),김홍자 ( Kim Hong Ja ),황일란 ( Hwang Il Lan ),류명수 ( Lyu Myeong Su ),( Kenneth H. Buetow ) 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-
<Aims> Fragile histidine triad (FHIT), located within chromosome 3p14.2, has been known to be one of molecular targets as the candidate tumor suppressor involved in the development of several human tumors. <Methods> In order to define the pathogenetic rol