시판 요구르트의 비피더스균수 및 유산균수의 비교

최선규,김경민,강국희 성균관대학교 생명과학자원연구소 1996 生命資源科學硏究 Vol.3 No.1

This study was carried out to count of the number of lactic acid bacteria and bifido bacteria in commercial yogurts during transportation. Yogurts were collected from supermarkets in Suwon area and were stored at 10℃. Titratable acidity, pH, bifidobacteria count, and lactic acid bacteria count of commercial yoghurts. Titratable acidity was slowly increased from 0.8% to 1.2% and pH decreased from 3.88 to 4.5 at 10℃ during 12 days. Total range of lactic acid bacteria of the yogurts were 10^8-10^9 cfu/ml. For the bifidobacteria, some samples of B, N, P, S indicated 103.8-106 cfu/ml and products H, M, Y showed 10^7.8-10^8.8 cfu/ml during storage for 10 days. The number of lactic acid bacteria in all the sample products were contained over than 10^7 cfu/ml with regal level during transportation.

진행된 HIV 감염 환자에서 십이지장의 미란성 병변으로 발현한 Mycobacterium genavense 감염 1예

진상만,박종선,김홍빈,오명돈,최강원,김희연,국윤호,김남중 대한감염학회 2007 감염과 화학요법 Vol.39 No.4

Mycobacterium genauense는 최근에 알려진 미코박테륨으로서, 식욕 부진, 체중 감소, 설사, 림프절 병증 등 파종성 Myocobacterium avium-intracellulare complex 감염과 유사한 임상상을 보이며, 위장관 침범을 잘 하는 것으로 알려져 있으나 아직 국내에서 증례는 보고된 바가 없다. 저자들은 진행된 HIV 감염 환자에서 십이지장의 미란성 병변으로 발현한 Mycobacterium genavense 감염 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. 환자는 상복부 동통과 발열, 설사로 내원하였다. 십이지장의 미란성 병변에서 시행한 조직검사에서 항산균이 가득 차있는 거품세포가 관찰되었으며, 이 검체에서 16S rRNA 유전자의 중합연쇄반응 검사를 시행하여 Mycobacterium genavense를 확인하였다. Mycobacterium genavense, first identified in 1990, is known as a pathogen that mimics disseminated Myocobacterium avium-intracellulare complex (MAC) infection with particular propensity for the gastrointestinal tract. In Korea, no case with the organism has been reported. Herein we report a case of Mycobacterium genavense infection that manifested with erosive lesion of duodenum in a patient with acquired immune deficiency syndrome. The patient presented with epigastric pain and fever, diarrhea. Duodenal biopsy showed histiocytic infiltration with numerous acid-fast bacilli. Identification of the mycobacterial isolate by the polymerase chain reaction restriction analysis of 16S rRNA gene revealed Mycobacterium genavense.

관해유도 화학요법을 받는 급성 백혈병 환자에서 발생한 감염증에서 Imipenem 단독요법과 Ceftizoxime + Amikacin 병용요법의 효과 및 안전성에 관한 전향적 비교 연구

신형식,김성민,이기형,최희정,김남중,오명돈,박선량,김병국,최강원 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.2

A total of 40 febrile granulocytopenic patients with acute leukemia were randomized to receive imipenem-cilastatin or ceftizoxime plus amikacin as initial empirical therapy to compare the efficacy and safety of imipenem monotherapy with that of ceftizoxime/amikacin combination therapy. 21 patients were randomized to the imipenem monotherapy, while 19 patients to the ceftizoxime/amikacin combination therapy. On 72 hour assessment success rates accordings to NCI criteria were 100% in both groups, success rates according to IHS (Immunocompremised Host Society) criteria were 55.0% in imipenem group and 66.7% in ceftizoxime/amikacin group. On overall assessment success rates according to NCI criteria were 90.0% in imipenem group and 94.7% in combination group, success rates according to IHS criteria were 50% in both groups. There was no statistical difference in success rate between two groups. Hepatotoxicity was the most common side effect in both groups(imipenem 15.0% vs. ceftizoxime/amikacin 15.8%). There was no CNS tixicity in both groups. Nausea and vomiting occurred in 9.5% of imipenem recipients, and 1 patients was unable to complete therapy due to intolerance. In summary, imipemem monotherapy was effective and safe empirical antibiotic therapy as compared with ceftizoxime/amikacin combination therapy.

발아조건과 배지종류 및 양액 농도에 따른 식물공장 재배 청경채와 상추의 묘 생육특성

최효길(Hyo-Gil Choi),권준국(Joon-Kook Kwon),박경섭(Kyoung-Sub Park),강윤임(Yun-Im Kang),조명환(Myeong-Whan Cho),노일래(Il-Rae Rho),강남준(Nam-Jun Kang) (사)한국생물환경조절학회 2011 생물환경조절학회지 Vol.20 No.4

본 연구는 식물공장에서 청경채와 상추의 발아조건과 육묘배지 및 육묘 시 양액농도가 묘의 생육에 미치는 영향을 구명하고자 수행되었다. 청경채와 상추의 발아율은 광의 유무와 온도처리(15, 20, 25℃) 간에 유의적 차이가 없었으나, 육묘배지 간에는 우레탄스펀지의 경우 파종 전ㆍ후 수분관리 유ㆍ무에 따라 큰 차이를 보였다. 즉, 우레탄스펀지 배지에서 파종전ㆍ후 수분관리를 하지 않았을 경우 암면에 비해 발아율이 현저히 낮았으나, 수분관리를 해주었을 때에는 암면보다 발아율이 높았으며, 묘의 생육도 암면과 차이가 없었다. 그리고 청경채의 생체중은 EC 1.0dSㆍm?¹에서 1.5dSㆍm?¹에서보다 1.8배 무거웠고, 0.5dSㆍm?¹에서보다는 6배 무거웠다. 상추의 생체중 또한 EC 1.0dSㆍm?¹이 1.5dSㆍm?¹와 0.5dSㆍm?¹에 비해 1.7배와 3.5배 각각 무거웠다. This experiment was conducted to study the effects of germination condition, nursery media and nutrient concentration in plant factory on the growth characteristics of pak-choi and lettuce seedlings. The results showed that temperature (15, 20, 25℃) and light conditions (lighting and no lighting) had no significant effect on germination rate of pak-choi and lettuce, whereas the interaction of growing media (rockwool and urethane sponge) and moisture management before and after sowing had significant effect on germination percentage. In case of no moisture management before and after sowing, germination percentage was much higher in rockwool medium than urethane sponge medium. But germination percentage of urethane sponge was higher than that of rockwool with applying moisture before and after sowing. At the nutrient concentration of EC 1.0 dSㆍm?¹ the fresh weight of pak-choi was heavier than in EC 1.5 and 0.5 dSㆍm?¹ by 1.8 and 6.0 times, respectively. At the nutrient concentration of EC 1.0 dSㆍm?¹ the fresh weight of lettuce was also heavier than in EC 1.5 and 0.5 dSㆍm?¹ by 1.7 and 3.5 times, respectively.

[Free Paper] Single-Incision Laparoscopic Splenctomy versus Conventional Multiport Lapaoscopic Splenectomy

Kang Kook Choi,Jin Seok Heo,Dong Wook Choi,Seong Ho Choi,Min Jung Kim,Hyojun Park 대한외과학회 2011 대한외과학회 학술대회 초록집 Vol.2011 No.11

Synchronous double primary cancers associated with a choledochal cyst and anomalous pancreaticobiliary ductal union

Kang Kook Choi,Sae Byeol Choi,Seung Woo Park,Hyun Ki Kim,Young Nyun Park,Kyung Sik Kim 대한외과학회 2011 Annals of Surgical Treatment and Research(ASRT) Vol.81 No.4

A 60-year-old female was admitted with epigastric pain lasting a month. Preoperative diagnosis was choledochal cyst with anomalous pancreaticobiliaryductal union (APBDU), C-P type. A papillary mass measuring 2.5 × 1.9 cm was found adjacent to the pancreaticocholedochal junction. Gallbladder (GB) cancer was also observed. Pyloric-preserving pancreaticoduodenectomy (PPPD) was performed. The patient received adjuvant chemotherapy/radiation therapy on the tumor bed. The gallbladder cancer showed serosal invasion, while the bile duct cancer extended into the pancreas. Although common bile duct (CBD) cancer lesion showed focally positive for p53 and the gallbladder cancer lesion showed negative for p53, the Ki-67 labeling index of the CBD cancer and GB cancer were about 10% and 30%, respectively. Nine months after curative resection, a stricture on the subhepatic colon developed due to adjuvant radiation therapy. Localized peritoneal seedings were incidentally found during a right hemicolectomy. The patient underwent chemotherapy and had no evidence of tumor recurrence for two years after PPPD.

The incidence and configuration of the bifid mandibular canal in Koreans by using cone-beam computed tomography

Kang, Ju-Han,Lee, Kook-Sun,Oh, Min-Gyu,Choi, Hwa-Young,Lee, Sae-Rom,Oh, Song-Hee,Choi, Yoon-Joo,Kim, Gyu-Tae,Choi, Yong-Suk,Hwang, Eui-Hwan Korean Academy of Oral and Maxillofacial Radiology 2014 Imaging Science in Dentistry Vol.44 No.1

Purpose: This study was performed to investigate the incidence and configuration of the bifid mandibular canal in a Korean population by using cone-beam computed tomography (CBCT) imaging. Materials and Methods: CBCT images of 1933 patients (884 male and 1049 female) were evaluated using PSR-9000N and Alphard-Vega 3030 Dental CT units (Asahi Roentgen Ind. Co., Ltd, Kyoto, Japan). Image analysis was performed by using OnDemand3D software (CyberMed Inc., Seoul, Korea). The bifid mandibular canal was identified and classified into four types, namely, the forward canal, buccolingual canal, dental canal, and retromolar canal. Statistical analysis was performed by using the chi-squared test and one-way analysis of variance (ANOVA). Results: Bifid mandibular canals were observed in 198 (10.2%) of 1933 patients. The most frequently observed type of bifid mandibular canal was the retromolar canal (n=104, rate: 52.5%) without any significant difference among the incidence of each age and gender. The mean diameter of the accessory canal was 1.27 mm (range: 0.27-3.29 mm) without any significant difference among the mean diameter of each type of the bifid mandibular canal. The mean length of the bifid mandibular canals was 14.97mm(range: 2.17-38.8 mm) with only a significant difference between the dental canal and the other types. Conclusion: The bifid mandibular canal is not uncommon in Koreans and has a prevalence of 10.2% as indicated in the present study. It is suggested that a CBCT examination be recommended for detecting a bifid canal.

Intra-abdominal bronchogenic cyst

Kang Kook Choi,Ji-Youn Sung,Jung-Sun Kim,Min Jung Kim,Hyojun Park,Dong Wook Choi,Seong Ho Choi,Jin Seok Heo 한국간담췌외과학회 2012 한국간담췌외과학회지 Vol.16 No.2

An intra-abdominal bronchogenic cyst (BC) is a very rare congenital anomaly caused by abnormal budding of the developing tracheobronchial tree. Intra-abdominal BCs are reported as retroperitoneal masses in most cases, many of which are located on the left side of the midline, the perigastric area, the left adrenal gland, or the superior body of the pancreas. Intra-abdominal BCs are frequently misdiagnosed due to the rarity, location, and variable cystic content. We report five patients with intra-abdominal BCs who underwent surgery in a single institution. (Korean J Hepatobiliary Pancreat Surg 2012;16:75-79)

Immediately transcripted genes in various hepatic ischemia models

Kang Kook Choi,Jin A Cho,Se Hoon Kim,Sang Woo Lee,Seon Ok Min,Kyung Sik Kim 대한외과학회 2012 Annals of Surgical Treatment and Research(ASRT) Vol.83 No.5

Purpose: To elucidate the characteristic gene transcription profiles among various hepatic ischemia conditions, immediately transcribed genes and the degree of ischemic injury were compared among total ischemia (TI), intermittent clamping (IC), and ischemic preconditioning (IPC). Methods: Sprague-Dawley rats were equally divided into control (C, sham-operated), TI (ischemia for 90 minutes), IC (ischemia for 15 minutes and reperfusion for 5 minutes, repeated six times), and IPC (ischemia for 15 minutes, reperfusion for 5 minutes, and ischemia again for 90 minutes) groups. A cDNA microarray analysis was performed using hepatic tissues obtained by partial hepatectomy after occluding hepatic inflow. Results: The cDNA microarray revealed the following: interleukin (IL)-1β expression was 2-fold greater in the TI group than in the C group. In the IC group, IL-1α/β expression increased by 2.5-fold, and Na+/K+ ATPase β1 expression decreased by 2.4-fold. In the IPC group, interferon regulatory factor-1, osteoprotegerin, and retinoblastoma-1 expression increased by approximately 2-fold compared to that in the C group, but the expression of Na+/K+ ATPase β1 decreased 3-fold. Conclusion: The current findings revealed characteristic gene expression profiles under various ischemic conditions. However, additional studies are needed to clarify the mechanism of protection against IPC.

Radical resection of intestinal blue rubber bleb nevus syndrome

Kang Kook Choi,Jin Yong Kim,Min Jung Kim,Hyojun Park,Dong Wook Choi,Seong Ho Choi,Jin Seok Heo 대한외과학회 2012 Annals of Surgical Treatment and Research(ASRT) Vol.83 No.5

Blue rubber bleb nevus syndrome (BRBNS) is a rare systemic vascular disorder characterized by multiple venous malformations involving many organs. BRBNS can occur in various organs, but the most frequently involved organs are the skin and gastrointestinal (GI) tract. GI lesions of BRBNS can cause acute or chronic bleeding, and treatment is challenging. Herein, we report a case of GI BRBNS that was successfully treated with a combination of intraoperative endoscopy and radical resection.