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      • A Study on the Effect of Physical Education in Chinese University on Student Satisfaction

        Junjun Yang(Junjun Yang),Li Wang(Li Wang) 동아시아무역학회 2022 Journal of East Asian Trade(JEAT) Vol.4 No.2

        Purpose - This study aims to understand the level and location of physical education at Chinese universities. Through the analysis of the Chinese sports industry and the government’s sports education policy, we will analyze the development process of Chinese sports education and the implementation process of the Chinese government’s sports policy to provide basic data on the future direction of Chinese sports education. Design/Methodology/Approach - The research method of this study analyzed the effect of physical education in China on student satisfaction through theoretical analysis and policy analysis on the Chinese sports industry and government and analyzed the development process of physical education and the implementation process of the Chinese government. Findings - The results of this study show the positive effect of physical education at Chinese universities on students’ satisfaction and academic achievement. Therefore, Chinese universities must devote more time and resources to physical education to improve students’ health and academic achievement. Research Implications - The limitation of this study is that when measuring the level of participation in sports activities, it may be difficult to grasp the overall level of participation in sports activities because it uses a qualitative measurement method or only measures some sports participation items. In addition, it can be difficult to generalize because the sample size is small to generalize the study results or because the study subject is limited to a specific university or region. Therefore, considering these limitations, finding ways to supplement the research results while actively utilizing them is necessary.

      • SCIESCOPUS

        Blasting wave pattern recognition based on Hilbert-Huang transform

        Li, Xuelong,Wang, Enyuan,Li, Zhonghui,Bie, Xiaofei,Chen, Liang,Feng, Junjun,Li, Nan Techno-Press 2016 Geomechanics & engineering Vol.11 No.5

        Rockburst is becoming more serious in Chinese coal mine. One of the effective methods to control rockburst is blasting. In the paper, we monitored and analyzed the blasting waves at different blast center distances by the Hilbert-Huang transform (HHT) in a coal mine. Results show that with the increase of blast center distance, the main frequency and amplitude of blasting waves show the decreasing trend. The attenuation of blasting waves is slower in the near blast field (10-75 m), compared with the far blast field (75-230 m). Besides, the frequency superposition phenomenon aggravates in the far field. A majority of the blasting waves energy at different blast center distances is concentrated around the IMF components 1-3. The instantaneous energy peak shows attenuation trend with the blast center distance increase, there are two obvious energy peaks in the near blast field (10-75 m), the energy spectrum appears "fat", and the total energy is greater. By contrast, there is only an energy peak in the far blast field, the energy spectrum is "thin", and the total energy is lesser. The HHT three dimensional spectrum shows that the wave energy accumulates in the time and frequency with the increasing of blast center distance.

      • KCI등재

        Characteristics of the gut microbiota colonization, inflammatory profile, and plasma metabolome in intrauterine growth restricted piglets during the first 12 hours after birth

        Shimeng Huang,Na Li,Cong Liu,Tiantian Li,Wei Wang,Lili Jiang,Zhen Li,Dandan Han,Shiyu Tao,Junjun Wang 한국미생물학회 2019 The journal of microbiology Vol.57 No.9

        Intrauterine growth restriction (IUGR) predisposes newborns to inflammatory and metabolic disturbance. Disequilibrium of gut microbiota in early life has been implicated in the incidence of inflammation and metabolic diseases in adulthood. This study aimed to investigate the difference in gut microbiota colonization, cytokines and plasma metabolome between IUGR and normal birth weight (NBW) piglets in early life. At birth, reduced (P < 0.05) body, jejunum, and ileum weights, as well as decreased (P < 0.05) small intestinal villi and increased (P < 0.05) ileal crypt depth were observed in IUGR piglets compared with their NBW counterparts. Imbalanced inflammatory and plasma metabolome profile was observed in IUGR piglets. Furthermore, altered metabolites were mainly involved in fatty acid metabolism and inflammatory response. At 12 h after birth and after suckling colostrum, reduced (P < 0.05) postnatal growth and the small intestinal maturation retardation (P < 0.05) continued in IUGR piglets in comparison with those in NBW littermates. Besides, the gut microbiota structure was significantly altered by IUGR. Importantly, the disruption of the inflammatory profile and metabolic status mainly involved the pro-inflammatory cytokines (IL-1β and IFN-γ) and amino acid metabolism. Moreover, spearman correlation analysis showed that the increased abundance of Escherichia-Shigella and decreased abundance of Clostridium_sensu_stricto_1 in IUGR piglets was closely associated with the alterations of slaughter weight, intestinal morphology, inflammatory cytokines, and plasma metabolites. Collectively, IUGR significantly impairs small intestine structure, modifies gut microbiota colonization, and disturbs inflammatory and metabolic profiles during the first 12 h after birth. The unbalanced gut microbiota mediated by IUGR contributes to the development of inflammation and metabolic diseases.

      • KCI등재

        Long Noncoding RNA Expression Profiling During the Neuronal Differentiation of Glial Precursor Cells from Rat Dorsal Root Ganglia

        Yunfei Dai,Wei Ma,Tong Zhang,Jinwei Yang,Chenghao Zang,Kuangpin Liu,Xianbin Wang,Jiawei Wang,Zhen Wu,Xingkui Zhang,Chunyan Li,Junjun Li,Xiangpeng Wang,Jianhui Guo,Liyan Li 한국생물공학회 2020 Biotechnology and Bioprocess Engineering Vol.25 No.3

        Long noncoding RNAs (lncRNAs) play important roles in the process of cell fate determination. However, their function and expression profiles have not yet been systematically investigated during the transdifferentiation of glial precursor cells derived from dorsal root ganglia (DRG) in the peripheral nervous system. Our results demonstrated significant differences in gene architecture and expression among the three transcript types (lncRNA, mRNA, and TUCP). Distinct differences in transcript length, exon number, and ORF length were identified between lncRNAs and mRNAs after comparative analysis of their structure and sequence conservation. We found that the upregulated lncRNAs outnumbered the downregulated lncRNAs in glial precursor cells cultured with proBDNF antiserum compared with the levels in glial precursor cells cultured without proBDNF antiserum. By a series of GO and KEGG analyses, we found that the effects of some lncRNAs on their target genes in cis were related to nerve growth factor-induced cell cycle, cell phenotype change, and neuronal differentiation. The qRT-PCR verification results of lncRNAs ENSRNOT00000091991, ENSRNOT00000087717, and LNC_000429 were mostly consistent with the sequencing results. The candidate lncRNAs may be associated with the neuronal transdifferentiation of glial precursor cells. Our study provides the first evidence for a remarkably diverse pattern of lncRNA expression during neuronal differentiation of glial precursor cells from rat DRG, and also provides a resource for lncRNA studies in the field of cell differentiation.

      • KCI등재

        Paleogene lacustrine dolomitization, Xingou region, southern Qianjiang Depression, China

        Junjun Shen,Bo Chen,Fangfang Chen,Chao Cheng,Yangfan Li,Ying Tian 한국지질과학협의회 2016 Geosciences Journal Vol.20 No.2

        The lacustrine dolomicrites of Unit II of the lower Xingouzui Formation deposited in the southern part of the Qianjiang Depression provide a good “tight carbonate” hydrocarbon reservoir. The dolomicrites are typically interbedded with and sourced from organic-rich argillite, which together form a source-reservoir assemblage characterized by thin single-layer thicknesses, far lateral extent and continuous lateral distribution. Systematic sedimentological and geochemical studies indicate that the depositional environment and organic matter evolution of the dark argillites (with TOC of 0.5–2%) are favorable for formation of the dolomicrites. The dolomicrite was mainly formed in a shallow-water evaporative environment; crystals are anhedral under SEM, in non-surface contact, and include a number of honeycomb intergranular micropores associated with replacement. The dolomicrite shows orange-orangered light by cathodoluminescence, indicative of association with minor terrigenous debris; X-ray diffraction results indicate that the dolomicrite is characterized by high calcium content (CaCO3 molar contents of 52.28–52.28%), low degree of orders of 0.2–0.4), and high content of Fe. The dolomicrite has δ18O values of 2.47–2.47‰ PDB, more positive than micrite, and δ13C values as moderately negative as 9.4–4.21‰ PDB, similar to micrite. Both values indicate the dolomicrite formed in a low-temperature genetic zone. Together, these characteristics indicate that the dolomicrite in the study area was formed in a high-salinity, confined lake basin, characterized by low temperature, shallow burial, and rapid nucleation and crystallization. The dolomicrite experienced a contemporaneous period with formation of dark mudstone, shale and calcite, and a penecontemporaneous period with formation of dolomicrite via seepage-reflux and a diagenetic period when ferrodolomite was formed via burial.

      • KCI등재

        Nicotine Induces the Expression of C-Reactive Protein via MAPK-Dependent Signal Pathway in U937 Macrophages

        Junjun Mao,Juntian Liu,Xiaoming Pang,Ming Li,Jinyan Song,Chunjie Han,Di Wu,Shuyue Wang 한국분자세포생물학회 2012 Molecules and cells Vol.34 No.5

        Atherosclerosis is an inflammatory disease in the vessel wall. Nicotine, a major component of cigarette smoke, is an independent risk factor for cardiovascular diseases including atherosclerosis. As an inflammatory molecule, C- reactive protein (CRP) participates in atherogenesis. Although it has been confirmed that CRP level in smoking patient is significantly higher than non-smokers and cigarette withdrawal,it is unknown whether nicotine induces CRP expression in macrophages. The present study was to observe effect of nicotine on CRP production and the related signal pathway in U937 macrophages. The results showed that nicotine significantly increased mRNA and protein expression of CRP in U937 macrophages in time- and concentration-dependent ways. Nicotinic acetylcholine receptor (nAChR) blocker hexamethonium, MEK1/2 inhibitor PD98059, p38 MAPK inhibitor SB203580 and NF-B inhibitor PDTC almost completely abolished nicotine-induced CRP expression in mRNA and protein levels in U937 macrophages. The further study indicated that hexa-methonium, PD98059, and SB203580 significantly inhibited ERK1/2 and p38 MAPK phosphorylation. These demonstrate that nicotine has ability to induce CRP ex-pression in macrophages through nAChR-ERK1/2/p38 MAPK-NF-B signal pathway, which contributes to better understanding of the pro-inflammatory and pro-atherosclerotic effects of nicotine in cigarette smokers.

      • KCI등재

        Effectiveness of craniotomy and long- term survival in 35 patients with gestational trophoblastic neoplasia with brain metastases: a clinical retrospective analysis

        Yuan Li,Weidi Wang,Xirun Wan,Fengzhi Feng,Yong-Lan He,Junjun Yang,Yang Xiang 대한부인종양학회 2022 Journal of Gynecologic Oncology Vol.33 No.3

        Objective: To investigate the clinical characteristics, treatments, and prognostic factors among patients with gestational trophoblastic neoplasia (GTN) exhibiting brain metastases who underwent craniotomy. Methods: Thirty-five patients with GTN who had brain metastases and subsequently underwent craniotomies between January 1990 and December 2018 at Peking Union Medical College Hospital were identified using the GTN database. Their clinical manifestations, treatments, outcomes, and prognostic factors were retrospectively analyzed. Results: All 35 patients underwent decompressive craniotomy, hematoma removal, and metastatic tumor resection combined with multiagent chemotherapy. Eighty percent (28/35) achieved complete remission, 11.4% (4/35) achieved partial remission, and 8.6% (3/35) had progressive disease. Not counting 2 patients who were lost to follow-up, 81.8% of the patients (27/33) were alive after a median follow-up of 72 months. The 5-year overall survival rate was 80.4%. Univariate analysis revealed that a history of chemotherapy failure (p=0.020) and a >1-week interval between craniotomy and chemotherapy commencement (p=0.027) were adverse risk factors for survival. Multivariate analysis showed that previous chemotherapy failure remained an independent risk factor for poor survival (odds ratio=11.50; 95% confidence interval=1.55–85.15; p=0.017). Conclusion: Decompressive craniotomy is a life-saving option if metastatic hemorrhage and intracranial hypertension produce a risk of cerebral hernia in patients with GTN who have brain metastases. Higher survival rates and improved prognoses can be achieved through perioperative multidisciplinary cooperation and timely standard postoperative chemotherapy.

      • SCIESCOPUS

        Investigation on energy dissipation and its mechanism of coal under dynamic loads

        Feng, Junjun,Wang, Enyuan,Shen, Rongxi,Chen, Liang,Li, Xuelong,Xu, Zhaoyong Techno-Press 2016 Geomechanics & engineering Vol.11 No.5

        The energy dissipation of coal under dynamic loads is a major issue in geomechanics and arising extensive concerns recently. In this study, dynamic loading tests of coal were conducted using a split Hopkinson pressure bar (SHPB) system, the characteristics of dynamic behavior and energy dissipation of coal were analyzed, and the mechanism of energy dissipation was discussed based on the fracture processes of coal under dynamic loads. Experimental results indicate that the energy dissipation of coal under dynamic loads has a positive linear correlation with both incident energy and dynamic compressive strength, and the correlation coefficients between incident energy, dynamic compressive strength and the energy dissipation rate are 0.74 and 0.98, respectively. Theoretical analysis demonstrates that higher level of stress leads to greater energy released during unstable crack propagation, thus resulting in larger energy dissipation rate of coal under dynamic loads. At last, a semi-empirical energy dissipation model is proposed for describing the positive relationship between dissipated energy and stress.

      • KCI등재

        Review of Vasectomy Complications and Safety Concerns

        Yang Fang,Li Junjun,Dong Liang,Tan Kun,Huang Xiaopeng,Zhang Peihai,Liu Xiaozhang,Chang Degui,Yu Xujun 대한남성과학회 2021 The World Journal of Men's Health Vol.39 No.3

        Vasectomy is a simple, safe, effective, and economical method used worldwide for long-term male contraception. As a sur-gical operation, it has short-term and long-term complications such as hematoma formation, infection, sterilization failure, sperm granulomas, short-term postoperative pain (nodal pain, scrotal pain, and ejaculation pain), and chronic pain syn-drome. Whether it increases the risk of autoimmune disease, cardiovascular disease, testicular cancer, or prostate cancer is still controversial. Changes in plasma concentrations of luteinizing hormone, follicle-stimulating hormone, and testosterone after vasectomy have also been studied, as well as the relation between vasectomy and sexual function. Sperm quality de-creases very slowly after vasectomy, and vasovasostomy and intracytoplasmic sperm injection could help a couple achieve a pregnancy if they change their minds at any point. We include a follow-up strategy and suggestions for follow-up care at the end of this review.

      • KCI등재

        Fabrication and mechanical properties of PLLA and CPC composite scaf-folds

        Shanglong Xu,Wei Guo,Junjun Lu,Wei Li 대한기계학회 2012 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.26 No.9

        The brittleness and insufficient strength of biomaterials such as calcium phosphate cement (CPC) limit their applications in physiologically non-load-bearing bone lesions. These limitations stimulated the research for developing degradable polymer-ceramic composite materials that can closely match the modulus of bones. In this study, poly (L-lactic acid)/calcium phosphate cement (PLLA/CPC) composite scaffolds were fabricated via a four-step process, namely, measurement, prototyping, compounding, and dissolving. The design and mechanical properties of the PLLA/CPC composite structures were theoretically and experimentally studied. The PLLA/CPC scaffold improved the mechanical properties of the CPC. The CPC’s compressive strength and strengthening percentage increase with higher PLLA volume. Such composites may have a clinical use for load-bearing bone fixation.

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