혈액 내 구리, 아연 및 ceruloplasmin 농도에 흡연, 음주 및 신체적 활동이 미치는 영향

홍연표,강은용,신인철,최병선,박정덕,장임원,박진완 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.4

Objectives : To investigate the influence of smoking, alcohol ingestion, and physical activity on copper and zinc in RBC and serum and serum ceruloplasmin, this study was performed in a cross-sectional study in 113 healthy men aged 20 to 40 years who had no symptomatic liver, heart, gastrointestinal, and other chronic diseases. Methods : At the men's entry into the study, blood samples were drawn from each subject and immediately centrifuged for analysis of copper, zinc, iron, ceruloplasmin, total cholesterol, and hematocrit. Each man completed a questionnaire that provided information on smoking, amount of alcohol intake, and physical activity. Partial regression analysis was performed on confounding variables such as age, body mass index, hematocrit, serum cholesterol, and serum iron. Results : In general linear models, adjustment for confounding variables did not show statistical differences, and there was only an increasing tendency in serum copper in heavy smoker(P=0.0678). There was no difference between high physical activity with mild smokers and lower physical with heavy smokers. Conclusions : This study suggested that copper, zinc and ceruloplasmin were not good biomarker for early effect by smoking, alcohol intake and physical activity in young adult. However, selection bias should be considered in evaluation of this result, and a large prospective study will be needed in advance on usefulness of copper, zinc and ceruloplasmin as a marker for risk factors and early change of atherosclerosis.

제품디자인에 있어서 인간공학 적용과정에 관한 연구 : Hand-Drill의 손잡이 형태에 빠른 EMG 적용을 중심으로 Focus on EMG Application for the shape of Hand-Drill Grip

홍성수,한정완 한국디자인과학학회 1998 디자인과학연구 Vol.1 No.-

디자인에서의 인간공학의 활용은 그동안 대단히 무질서하고, 난잡하게 적용되었다. 이것은 아직까지 디자인이 미술적 재능이나 경험적, 감각적인 재능의 부산물로 인식되기 때문에 이 시점에서 디자이너는 인간공학 도입의 본래의 취지에 맞게 디자인을 객관적, 정량적인 방법으로 수행해야 할 것이다. 따라서 본 연구는 EMG 시스템을 이용하여 Hand-Drill의 손잡형태가 팔근육에 미치는 영향에 대한 가설을 통하며 Hand-Drill디자인시 보다 객관적인 인간공학적 접근방법을 모색하고 적정각도 및 굵기를 정량적으로 제시하고자 한다. 이를 위해 5명의 신체 건강한 20대 피실험자을 대상으로 Hand-Drill 손잡이 각도 굵기를 독립변수, 팔근육에 미치는 힘을 종속변수로 설정하여 Hand-Drill의 각도와 굵기가 팔근육에 미치는 영향에 대해 조사 분석하였다. 측정된 자료를 통계분석한 결과 각도 0°, 굵기 2.56cm일 때 근육에 미치는 힘이 적게 나타났다. 본 연구의 결과는 제품디자인에 있어서 EMG 신호를 이용하여 각 형태를 인간공학적 방법으로 정량화 하였고, Hand-Drill 디자인에 있어 각도와 굵기에 대한 추천지로 제안 될 수 있다고 본다. 추후에는 진동, 단면적 형태, 무게 등의 독립변수 요인을 추가 확대하여 Hand-Drill 디자인에 응용한다면 더욱 유용하리라 생각된다. Human Factor, a practical science that is an application fields, has been employed and used in industrial importance. But we limited Human Factor on anthrome design work, and have used it as sensible data only. It is necessary that scientific, quantitized and responsib be applied in industrial design. In this paper, I propos design process can be used in EMG system of biom Human Factor with responsible and quantitized characteristics of EMG system is described and the cap application of EMG system of industrial design is pre-experiment. I applied this result to joystick leve hydraulic excavator. In this paper, 1 emphasize that objective aid standa applied to EMG system experiment process and indu process integratively. And I suggest that systematic method be applied to H in industrial design.

케이블 감속을 이용한 소형 로봇의 개발과 실시간 제어에 관한 연구

홍종성,이정완 江原大學校 産業技術硏究所 2002 産業技術硏究 Vol.22 No.B

In this thesis, a three degrees of freedom robot, which is able to provide sufficient precision for various robot researches, has been developed. The cable mechanism is used as a basic transmission of robot joints. Based on an optimal design strategy, link and joint parameters are determined and then overall geometry of the robot is designed. As an architecture of robot control, real time control system using real time linux and RtiC-Lab(Real Time Controls Laboratory) is developed. This system, written in C and based on Linux O/S, includes text editor, compiler, downloader, and real time plotter running in host computer for developing control purpose. Using these hardware and software, simple PD position control is implemented, the results shows the effectiveness of the system.

남성 사무직 근로자들의 직무스트레스와 간기능 이상과의 관련성

홍정연,김형렬,이보람,김용규,구정완,박정일 大韓産業醫學會 2009 대한직업환경의학회지 Vol.21 No.2

목적: 사무직 근로자의 직무스트레스와 간기능 이상의 관련성을 파악하고자 하였다. 방법: 근로자 건강검진에 참여한 남성 사무직 근로자 664명을 대상으로 응답자 직접 기입식 건강 검진 문진 및 한국인 직무스트레스 측정도구(Korean Occupational Stress Scale)의 결과와 각 근로자의 간기능 검사결과를 통해 간기능 이상에 영향을 주는 요인에 대해 분석하였다. 결과: 직무요구도 및 전체 직무스트레스 수준이 높은 군에서 간기능 이상률이 증가하였다. 음주 행동과 BMI에 따라 근로자 군을 분류하였을 때, 직무요구도 및 전체 직무스트레스 수준이 높은 군에서 간기능 이상률이 증가 하였다. 불건강 음주를 하는 군과 BMI 25이상 비만자군의 경우 직무스트레스의 수준이 간기능 이상에 중요한 역할을 하는 것으로 나타났다. 결론: 직무요구도 및 전체 직무스트레스 수준이 높은 군에서 간기능 이상과 관련성을 보였다. 따라서 직무스트레스의 조직적 관리 및 접근을 통해 간기능 건강에 기여 할 수 있을 것이다. Objectives: We wanted to investigate the relationship between job stress and liver dysfunction in Korean male white collar workers. Methods: A total of 700 male white collar workers who worked at one electronic institute and who participated in an annual surveillance program were recruited: 664(94.9%) workers were initially recruited and the data for 36 workers was excluded due to poor responses and a past history of liver disease. The questionnaire survey included the participants' general characteristics, the job-related factors, the health-related behaviors and job stress. Job stress was assessed using the Korean Occupational Stress Scale-Short Form (KOSS-SF). We merged the job stress data with the individual liver function results by conducting annual surveillance. Multiple logistic regression analysis with adjusting it for the Confounding variables, including alcohol drinking and the body mass index (BMI), was used to evaluate the relationship between job stress and liver dysfunction. Results: After adjustment for the confounding variables, the proportion of liver dysfunction cases was significantly higher in the groups with a high level of job stress, as assessed by the 'job demands and total score'. After conducting a stratified analysis with considering alcohol drinking and the BMI, the prevalence odds ratio of liver dysfunction was higher in the groups with a high level of job stress, as assessed by the 'job demands and total score'. Conclusions: The results of this study suggest that the level of job stress (and especially that assessed by the job demands and total score) is related to liver dysfunction. Thus, further preventive efforts and studies are needed to reduce job stress and address liver dysfunction.

고분자 전지용 Polypyrrole/Sulfonated-poly(2,6-dimethyl-1,4-phenylene oxide) 복합전극의 전기화학적 특성

정홍련,김찬,양갑승,이완진 한국공업화학회 2004 응용화학 Vol.8 No.1

Polypyrrole/PPO and polypyrrole/SPPO, conducting polymer composite, were made by a oxidative chemical polymerization with changing the contents of pyrrole and PPO using FeCl₃ act as a dopant and a initiator. The electrode was made by hot press on Cu exmat after mix conducting polymer composite and Super-P, and was examined electrochemical characteristics to penetrate to 1 M LiClO₄ + PC/DMC. The charge-discharge performance of the PPy/SPPO composite electrode was increased the extent of about 50 % compared to that of PPy/PPO. The reason is that the miscibility, contact area and affinity are promoted owing to the effect of sulfonation.

心拍數와 Pedometer Score에서 본 國民學校 體育授業時의 活動量 分析

홍상완,김영수,박정화 대구교육대학교 초등교육연구소 1995 초등교육연구논총 Vol.7 No.-

1.Utilizing ten boy elementary students among 47(forty-seven)members of forth grade class, our systematic and group learning study discovered by carrying our soccer lesson that the average of pedometer score(2226.8±608.6) of group learning was higher than that(1912.7±504.8)of systematic learning. 2.We found the pedometer score had nothing to do with the mean heart rate in our systematic and group learning. 3.The mean heart rate of group learning was meaningfully higher(P<0.05) than that of systematic learning. 4.The exercise duration of group learning was longer than that of systematic learning in the 80%HRmax above physiological exercise intensity to improve the cardiorespiratory.

혈액질환 환자에서 조혈모세포 이식과 화학요법 후의 침습성 진균감염의 분석

유진홍,최정현,이동건,최수미,신완식,김춘추 대한감염학회 2004 감염과 화학요법 Vol.36 No.1

목적 : 조혈모세포 이식이나 화학요법을 받은 혈액질환 환자에서 침습성 진균감염의 양상을 분석하고 예후 인자를 정하기 위하여 이 연구를 실시하였다. 방법 : 2000년 3월부터 2001년 2월까지 가톨릭 조혈모세포이식센터에 입원한 318명의 환자들 중 진균 감염으로 의심되어 항진균제를 투여받은 122명의 환자를 대상으로 후향적 분석을 실시하였다. 결과 : 74명의 환자가 EORTC/MSG 기준에 의해 침습성 진균증으로 판정되었다. 이들 중 6명이 확진이었고, 46명이 추정, 22명이 가능 증례이었다. 가장 많이 침습된 장기는 하부 호흡기이었다(72/74). 사망률은 32.4%이었다. 단변량 분석으로 예후 인자를 도출한 결과 입원 기간, 진단까지 걸린 시일, 그리고 amphotericin B의 총 투여량이 유의한 인자로 나왔다. 그러나 다변량 분석을 시행한 결과 입원 기간만이 독립적으로 유의하게 영향을 미치는 예후 인자로 산출되었다. 결론 : 침습성 진균 감염은 현재도 조혈모세포 이식이나 화학요법 후의 중요한 합병증으로 작용하고 있음을 알 수 있었다. 진균 감염 합병증의 예후에 영향을 미치는 요소로 입원 기간이외에 진단의 신속성과 항진균제의 투여도 유의한지에 대해서는 후속 연구를 통해 재치 규명해야 할 것으로 생각된다. Background : Invasive fungal infections (IFI) are one type of representing total infections in compromised patients. To analyze the characteristics and to determine the prognostic factors of IFI in patients with hematologic diseases undergoing hematopoietic stem cell transplantation (HSCT) and/or chemotherapy. Methods : We retrospectively reviewed consecutive patients (n=122) who received antifungal treatment with the impression of fungal infection complicating post-HSCT or chemotherapy from March-2000 to February-2001. Results : Seventy-four out of 122 registered patients belonged to the IFI on the basis of EORTC/MSG criteria. Six patients were proven IFI, 46 were probable, and 22 were in the category of possible one. The most commonly involved organ was lower respiratory tract (72/74). The mortality was 32.4%. Univariate analysis revealed duration of hospitalization, days to diagnosis of IFI, and total amount of amphotericin B as significant prognostic factors. But multivariate analysis determined only duration of hospitalization from these variables as an independently influencing factor on the prognosis. Conclusion : Invasive fungal infection is still the major threatening complication of HSCT and chemotherapy. Further follow-up and extension of this study is necessary to elucidate more prognostic factors.

데드링크 시각화에 관한 연구

김완규,김현주,김일,정연홍 진주산업대학교 산업과학기술연구소 2007 산업과학기술연구소보 Vol.- No.14

Web mining is to extract useful information for homepage management by analyzing the structures, contents and usages of web pages. The web mining is classified into structure mining, content mining and usage mining. Web crawler is a representative tool that has been used in the structure mining. Not only the web crawler has a function to analyze the link structures among webpages and accumulate information, but also it is used to resolve problems by finding out link errors on homepages. But this web crawler uses a way of analyzing based on texts, so it takes so much time and costs a lot to find out locations of errors. As a result, most of homepages just leave these link errors unsettled. In this paper, we design and implement an analyzing system of link errors on hyperlinked environment in order to improve defects and increase efficiency of links on homepages. In addition, this system which we propose analyzes the location and size of hyperlinks, and provides visual information whether a link is successfully connected or not.

김치유래 젖산균의 균체지방산 분석을 이용한 분류학적 연구

이정숙,정민철,김우식,이근철,김홍중,박찬선,이헌주,주윤정,이근종,안종석,박완,박용하,민태익 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.2

표준균주를 포함한 230여개의 김치유래 젖산균에 대한 균체지방산(FAMEs)을 분석하였다. FAMEs profiles는 Euclidian Distance 17.5에 의해 7개의 Major Cluster와 1개의 Single Cluster로 나뉘어졌다. 이중 A, B, C 및 Cluster는 Leuconostoc속으로 분석되어졌고, F는 Lactobacillus속으로 분석되어졌다. 그리고 E와 G cluster는 두개의 Genus가 혼재되어 나타났으며 보충적인 연구가 필요하다. 앞으로 김치유래 젖산균의 균체지방산 분석결과를 기반으로 한 데이타베이스에 95가지 탄소원을 이용하는 수치분류학적 접근방법 및 Pyrolysis Mass Spectrometry 등의 화학적 분석 방법과 분자친화적 연구를 통한 종합적 분류정보 체계가 갖추어지면 젖산균의 신속, 정확한 동정 및 연구에 활발히 이용되어질 것이다. Two hundreds and thirty lactic acid bacteria, mostly isolated from Kimchi, including type strains were sued for analysis of cellular fatty acids. The 230 test strains were recoverd in 7 major and 1 single clusters defined a Euclidian distance of 17.5. These aggregate taxa were equivalent to the genus Leuconostoc (aggregate group A, B, C and D), and the genera Leuconostoc and Lactobacillus (aggregate group G). It is concluded as evident that FAMEs (Fatty Acid Methyl Esters) profile of cell can be used as a criterion in classification of lactic acid bacterial from kimchi. Additional comparative taxonomic studies need to be carried out on well chosen representative strains to determine the most appropriate methods of value.

간내 담관암의 초음파 및 전산화 단층촬영소견 : Ultrasound and CT Findings

김완진,김표년,김일영,홍현숙,이혜경,권귀향,김기정 순천향대학교 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1