판막 질환에서의 심근 섬유화 : 심근 조직을 이용한 형태학적 연구 및 혈청 생화학적 지표의 분석

강수진,박덕우,송재관,박경민,송종민,강덕현,한기훈,송현,이재원,주석중,송명근,김정선 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

미만성 경화 아형 갑상선 유두암 1예

최정민,이송주,김부경,최영식,박요한,김정훈,허방 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.1

The diffuse sclerosing variant (DSV) is a rare malignant tumour that accounts for 0.7-5.3% of all papillary thyroid cancers. DSV tends to occur at a younger age and has a higher incidence of cervical lymph node metastases, compared with papillary thyroid carcinoma. A 62-year-old female patient diagnosed thyroid nodule with diffuse and mild increased 18F-deoxy-glucose (FDG) on FDG positron emission tomography (PET)-computed tomogram (CT) scan. The ultrasound images showed typical findings of DSV such as diffusely enlarged thyroid lobes and diffusely scattered microcalcification. We performed this patient ultrasonography guided fine needle aspiration and cytologic analysis revealed papillary carcinoma. Total thyroidectomy with central compartment node dissection and lateral lymph node dissection was performed and finally diagnosed DVS. The authors report this case with literature review.

Baculovirus를 이용한 Aujeszky's Disease Virus gⅢ 단백질 발현

송재영,이중복,현방훈,박종현,김병한,권창희,전무형,안수환 충남대학교 생물공학연구소 1993 생물공학연구지 Vol.3 No.-

The g Ⅲ gene located in U_L region of Yangsan strain, a field isolate of Aujeszky's disease virus (ADV) in Korea, was cloned into pTZ18R and sequenced. The gⅢ gene consisting of 1,437 nucleotides showed 98% sequence homology with that of Becker strain, a reference strain of ADV. The gene encoding gⅢ of Yangsan strain was placed under the control of Autographa californica nucleopolyhedrosis virus (AcNPV) polyhedrin promoter, and expressed by the derived recombinant baculovirus using Spodoptera frugiperda 9 (Sf9) cells. The expressed gⅢ was a protein with molecular weight of 72kd determined by immunoprecipitation and Western blotting assay using anti-ADV polyclonal antibodies and anti-gⅢ monoclonal antibody. The partially purified gⅢ protein was utilized as antigen in the radial immunodiffusion enzyme assay (RIDEA) to detect to specific antibody against ADV in pig sera. The results indicated that the sensitivity of RIDEA with the recombinant gⅢ protein antigen (98%) was as high as that with the conventional glycoprotein antigen extracted from the ADV infected cells. In addition, the false positive and false nagative reactions in gⅢ RIDEA were significantly reduced than the conventional glycoprotein RIDEA as judged from the results of standard serum neutralization test.

초정밀 마이크로 물성평가를 위한 비전변형률 측정모듈 개발

한아름,이혜진,이낙규,이근안,송정한 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

Researches about micro technology travel lively in these days. Such many researches are concentrated in the field of micro materials and a process field. But properties of micro materials should be known to give results of research developed into still more. In these various material properties, reliability data such as mechanical, optical, thermal property, etc is the basic property. In this paper, it is developed that is Strain measurement module for micro material property system.

뇌동맥류의 진단에 대한 전산화단층촬영 뇌혈관조영술과 고식적 뇌혈관조영술의 비교

송상현,윤수한,안영환,안영민,조기홍,조경기,김선용,서정호 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.10

Cerebral angiography has been essential for the diagnosis of the intracranial aneurysms but. is sometimes accompanied by serious complications. Resolution of CT angiography was up-graded greatly to represent the three-demensional structure of vesseles since helical CT had been introduced. We have compared 26 cases of CT angiography and 28 cases of conventional angiography in terms of specificity and sensitivity for the diagnosis detectable aneurysm diameter. configurational diagnosis and diagnostic confidency. All results showed no statistical difference between CT angiography and conventional angiography. These should suggest that CT angiography could be replaced with conventional angiography for the diagnosis of ruptured aneurysms and even of unruptured aneurysms. resulting in the introduction of first screening modality of unruptured aneurysms.

지연성근육통에 대한 수지요법의 효과

송영래,정한영 한국학교체육학회 2001 한국학교 체육학회지 Vol.11 No.2

지연성 근육통에 대한 예방과 치료법은 다양하다. 그러나 아직까지 명확한 치료법은 밝혀지지 않았다. 따라서 본 연구는 수지요법이 지연성 근육통에 대한 예방과 치료법의 대안으로 적합한지를 보기 위하여 수지요법을 이용한 통증역치의 변화를 알아보았다. 실험에 참가한 대상자는 5대학교에 재학중인 건강한 여학생 18명으로 실험군과 대조군에 9명씩 무작위 배치하였다. 지연성 근육통은 슬관절 굴곡근과 신전근에 등속성 운동을 시행하여 유발하였으며, 통증역치의 수치는 지연성 근육통을 유발하기 전과 후, 그리고 치료 후 각각 3회 측정되었다. 실험군에서는 30분의 수지요법 치료과정을 거쳤 고 대조군은 치료과정이 없었다. 연구의 결과 실험군에서 치료 후의 통증역치는 치료전에 비해서 상승하였으며 통계학적으로 유의한 차이가 있었다(p<.05). 대조군은 치료 전·후에 유의한 차이가 없었다(p<.05). 치료 전·후의 실험군과 대조군의 통증역치의 변화량을 비교한 결과 실험군의 통증역치의 변화량이 대조군보다 유의하게 높았다(p<.05). 이상과 같은 결과로 지인성 근육통에 대한 수지요법의 적용은 효과적이라 할 수 있으며, 앞으로의 연구는 그 기전에 대하여 다루어져야 할 것이다. There are diverse prevention and treatment methods for Delayed Onset Muscle Soreness(DOMS). There are, however, controversy regarding effective treatment methods. Therefore, the purposes of this study were 1) to determine the changes between pre and post-treatment of two groups of 18 people and 2) to examine the effect of Koryo Hand Therapy on pressure threshold. DOMS was induced when isometric exercise were performed the flexor muscle and extensor muscle of knee joint. Eighteen healthy subjects (female=18) aged 20 to 23 years were randomly assigned to one of two troups. Group 1 received Koryo Hand Therapy to the appropriate hand points for DOMS of knee flexor muscle. Group 2 received no treatment and served as control. Pain threshold at the knee joint. Determined by a painful Apbong before and 30minutes after hand stimulation. Experimenta3 group was the only group that showed statistically significant increase(p <.05) in pain threshold. These results suggest that Koryo Hand Therapy has the capability to increase pain threshold.

골형태분석법과 micro-CT를 이용한 골소주 특성에 대한 연구

송영한,이완,이창진,지정현,이병도 대한구강악안면방사선학회 2007 Imaging Science in Dentistry Vol.36 No.1

Purpose : The research was done to investigate the effectiveness of 2D bony morphometry and microstructure of micro-computed tomography (micro-CT) on the osteoporotic bony change. We performed the bone morphometric analysis of proximal femur in ovariectomized rabbits with BMD and micro-CT examination. Materials and Methods : Twenty-one female (Newzealand, about 16 weeks old, 2.9-3.4 kg) rabbits were used. Three rabbits were sacrificed on the day when experiment began (Baseline). The remaining 18 rabbits were divided into two groups. One group was ovariectomized bilaterally (OVX) and the other animals were subjected to sham operation (Sham). Bone specimens were obtained from the right and left femur of sacrificed rabbits. At intervals of 1, 2, 3, 5, 6 months respectively, BMD tests were performed on the proximal femur by using PIXImus 2 (GE Lunar Co. USA), 2-dimensional bone morphometric analysis by custome computer program and 2D/3D bone structure analysis by micro-CT (Skyscan1072, Antwerpen, Belgium). Statistical analysis was carried out for the correlation between bone morphometry , micro-CT and BMD Result : BV/TV, Tb.Th, Tb.N of micro-CT parameters showed higher values in sham group than OVX group. N.Nd/Ar.RI, N.NdNd, N.NdTm, N. TmTm, PmB/Ar.RI, 3-D BoxSlope of 2D morphometric parameters showed higher values in Sham group than OVX group. The micro-CT parameters of Tb.Sp, Tb.N were statistically significant correlated with BMD respectively. Several 2D morphometric parameters were statistically significant correlated with BMD respectively. Conclusion : Several parameters of 2D bony morphometry and micro-CT showed effective aspects on the osteoporotic bony change. (Korean J Oral Maxillofac Radiol 2007; 37 : 27-33)

간내 담관 낭선종

송일한,김정택 단국대학교 2000 論文集 Vol.35 No.-

Hepatobiliary cystadenoma is a rate but distinct neoplasm with malignant potential, similar to that occuring in the pancreas or ovary. The differential diagnosis of hepatobiliary cystadenoma includes other cystic neoplasms, primary and metastatic, and nonneoplastic cysts including infective conditions. A preoperative distinction from hydatid disease, difficult on radiologic grounds alone, is particulary important. We report a 38-year-old woman admitted because of intermittent epigastric pain. Abdominal ultrasonography, CT and MRI revealed about 15×10㎝ sized multiloculated cystic lesion in medial segment of left lobe of the liver. Hydatid serologic analysis was normal. But serum level of CA 19-9 was raised above 2400U/mL. Under ultrasonographic guidence, we performed aspiration of the cystic fluid. In the examination of cystic fluid, malignant cell was abscent and cystic fluid level of CA 19-9 was also rasied above 2400U/mL. Under the impression of hepatobiliary cystadenoma, laparotomy was performed. A 15×10㎝ sized cystic mass was noted in the medial segment of left lobe of the liver, and then left lobectomy was done. On cut section, 1800mL of serous fluid was obtained from the multiloculated cystic mass. Microscopic findings revealed a cystadenoma lined by a single layer of columnar epithelium containing some intracellular mucin pools and hemorrhagic infact without evidence of cellular atypism or mitosis.

척수종양의 임상적 관찰

송재욱,김수한,우정현 全南大醫大 1987 전남의대학술지 Vol.24 No.1

고효율 폐페인트의 재활용 기술 개발

정재헌,김정수,김종민,김영한,이상록,장상목 동아대학교 공과대학부설 생산기술연구소 1997 生産技術硏究所硏究論文集 Vol.2 No.1

In this study, the equipment and method to recyle waste-paint, were developed and investigated. The efficiency of drying and pulverizing the waste-paint were improved via vescosity reducing process and microwave energy source with a blast of hot air. This method may be useful to recyle the waste-paint, rubber and plastics.