흉선종 제거후에 발생한 재생 불량성 빈혈 : 증례보고

전원선,이상철,김현정,배상병,김찬규,이남수,박노진,이규택,박성규,홍대식,박희숙,원종호 순천향의학연구소 2007 Journal of Soonchunhyang Medical Science Vol.13 No.2

Thymoma is associated with myasthenia gravis, Pure red cell aplasia, and autoimmune diseases such as autoimmune hemolytic anemia, aplastic anemia, and hypogammaglobulinemia. It's association with aplastic anemia is rare and aplastic anemia appearing after surgical removal of thymoma is especially rare. The authors hereby report a case of aplastic anemia occuring in a patient who was diagnosed with thymoma and myasthenia gravis and had the tumor surgically removed. The patient was treated with anti-thymocyte globulin, cyclosporin, and prednisolone, and showed partial remission with hematologic improvements after 12 months.

Southern Blot Hybridization법을 이용한 악성 림프종의 면역유전형에 관한 연구

전호종,기근홍,김윤신,이미숙,이미자,장원재,장숙진,박영진,정춘해,정종훈,양성훈,이광민 조선대학교 1994 The Medical Journal of Chosun University Vol.19 No.2

Immunogenotyping using gene rearrangement analysis has emerged as a precise laboratory aid in the diagnosis and classification of malignant Iymphoid neoplasms. The lineage and clonality of the malignant Iymphoid neoplasms can be identified by the demonstration of rearrangements of antigen receptor genes of the immunoglobulin and T-cell receptor genes. The analysis of the gene rearrangements on the malignant Iymphoid neoplasms are also useful as a sensitive unique clonal markers to detect early recurrence in patients with malignant Iymphoid neoplasms after treatment. To analyze the sensitivity and specificity of gene rearrangements in the diagnosis of malignant Iymphoid neoplasms. 24 cases of malignat Iymphoma were examined by Southern blot hybridization using CTβ-T cell receptor β chain gene-DNA probe and JH-immunoglobulin heavy chain gene-DNA probe. The results of the immunogenotypings using Southern blot hybridization disclosed high correlation between the immunophenotyping using immunohistochemical stain with monoclonal antibodies (B-cell Iymphoma 84.2%. T-cell Iymphoma 75% ). The analysis of the gene rearrangement of the angioimmunoblastic lymphadenopathy(AILD) and unclassifiable Iymphoma using immunohistochemical stain could resolve the monoclonality and lineage . Rearranged bands to the CTβDNA probe were observed in one case out of 2 cases of AILD. One case of unclassifiable Iymphoma showed rearranged bands to the CTβ DNA probe. There were no rearrangements in reactive follicular Iymphoid hyperplasia and paracortical Iymphoid hyperplasia. In conclusion, DNA gene rearrangement study should be applied to differentiate the clonality and cell lineage in the malignant Iymphoma with indistinctive immunophenotype.

IMT-2000 휴대용 멀티미디어 기기디자인에 관한 연구

전종찬,심춘호 한국기초조형학회 2002 기초조형학연구 Vol.3 No.2

통신시장이 하루가 다르게 변하고 있다. 지금까지 유선통신이 통신시장의 주류를 형성했다면, 최근 이동통신의 급속한 성장으로 인해 지난해부터 가입자수 기준으로 이동통신이 유선통신을 추월해 시장의 주류가 이동통신으로 변하고 있다. 특히 IMT-2000의 등장으로 더욱 편리하고 더욱 신속한 정보 및 화상, 무선 인터넷 등 다양한 서비스를 제공 받을 수 있는 휴대용 멀티미디어 기기들이 출현하게 되었다. 본 연구에서는 MOBILE MULTIMEDIA 시대에 대비하여 휴대용 멀티미디어 시스템의 일반적 고찰을 통해 현재와 미래를 예측하여 보고, 연구방향 설정을 위해 멀티미디어 시대의 사회적 변화 및 현대 사회의 공통된 객관적 요구를 파악하고, 국내외 멀티미디어 시스템의 시장성 분석과, 사용자 Life Style, 기존 제품의 회사별 비교 분석을 통하여 방향 설정을 하였다. 구체적으로 형태와 색상, 그리고 기능에 대해서는 유저들의 Life Style의 분석 자료를 바탕으로 향후 디자인을 위한 CONCEPT을 설정하였다. 형태의 방향설정의 경우, 경제적 능력이 어느 정도 있으며 패션에 아주 예민한 1925세대와 경제적으로 독립되고 홈뱅킹과 사이버 트레이딩을 자주하며 기술에 민감한 자동차 애호파 2632세대를 본 디자인의 수요층으로 설정했기 때문에 스타일면에서 Cyber, Casual을 복합적으로 구성할 수 있는 형태 즉 미래지향적인 느낌의 형태를 지향하였으며 단순성, 복합성, 편리성을 추구하였다. 특히 복합성은 다기능과 성능을 갖춘 제품으로서의 기능이며, 이를 바탕으로 통합 개념 모델의 디자인 방향을 개념으로 설정하였다. The communication markets are changing everyday. Recently, the wire communications had dominated the markets, but lately, the mobile or wireless communications have been growing rapidly. Since last year, the number of mobile communication subscribes began to exceed that of sire communication ones. Thus, the focus of communications markets is shifting from wire to wireless, in particular, as IMT-2000 emerges, we are witnessing various mobile multi-media communication devices characterized by more convenient and faster information and screen image services, wireless internet access and other various functions. To this end, mobile multi-media systems are examined in preparation for the age of mobile multi-media to get a perspective into their future technology and designs. While the social changes and common or objective needs of our modern society are reviewed. The domestic and foreign multi-media system markets are analyzed, and thereupon, users' life styles and existing multi-media products are comparatively analyzed to set a desirable direction for the multi-media mobile industry. Based in shapes, colors, functions and users' life styles analyzed, future design concepts for the mobile multi-media are reviewed.

C₄유분을 이용한 옥텐류의 합성에 있어서 1,3-Butadiene의 함량에 따른 이량화 촉매의 수명에 관한 연구

전종기,한원희,조정호,고승태,노상균 동양대학교 2001 동양대학교 논문집 Vol.7 No.1

Selective hydrogenation of 1,3-butadiene in C4 raffinate was carried out in fixed bed reactor using Pd/a1unina catalysts, Concentration of 1,3-butadiene in C4 raffinate could be reduced under 100 ppm.The life of dimerization catalyst using C4 raffinate after selective hydrogenation was longer than that of dimerization catalyst without selective hydrogenation.It was found that dilution of olefin concentration in feed was effective to increase dimerization catalyst life.

남성유방에 발생한 지방육종

최종범,임성철,기근홍,전호종,서재홍 대한병리학회 1992 Journal of Pathology and Translational Medicine Vol.26 No.3

노인의 운동유형에 따른 혈관탄성과 혈압의 반응

전용수,김일곤,이종호,차진 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

The purpose of this study was to analyze the response of Vascular Compliance and blood pressure on aerobic, muscular endurance, stretching exercise and to ascertain the best effects of exercise for improve vascular health in the Elderly men, The subjects were 20 old men, I measured blood pressure and vascular compliance pre and post exercise. For the data, all the measurement were represented by mean(M) and standard deviation(SD) using SPSS package(version 10.0). Statistical techniques for data analysis were paired t-test to determine the difference in pre-post data into group and were one-way ANOVA to determine the rank between group, The Conclusions of this study were as follows; 1. The vascular compliance(p<.01) and blood pressure(p<.05) showed significant differences between pre and post exercise in aerobic exercise groups, 2, The vascular compliance(p<.000) and blood pressure(p<.01) showed significant differences between pre and post exercise in muscular endurance exercise. 3. The vascular compliance(p<.000) and the systolic blood(p<.01) showed significant differences between pre and post exercise in stretching exercise, But diastolic blood pressure showed no significant(p<.437) differences between pre and post exercise. 4. The vascular compliance showed significant(p<.05) only left ankle which differences in order of muscular endurance, stretching, aerobic post-exercise between group. The systolic blood pressure showed significant(p<.001) which differences in order of aerobic, muscular endurance, stretching and the diastolic blood pressure showed significant(p<.01) which differences in order of muscular endurance, aerobic, stretching past-exercise between group.

DMN과 GALN에 의한 간세포손상이 신사구체의 면역글로부린 침착에 미치는 영향에 관한 실험적 연구

전호종,설주문,김수홍 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.2

Glomerular IgA deposition often occured in prolonged hepatobiliary disease and also it's definite pathogenesis is not yet cleared, In the present study, liver injury was induced by intraperitoneal administration of single dose of dimethylnitrosamine and D-galactosamine in rats to investigate the pathogenesis of glomerular Ig A deposition by observations of immunohistochemical and special stains. The results obtained were as follows 1. In the dimethylnitrosamine-treated rats, there were extensive blood-filled necrotic spaces containing debris of necrotic hepatocytes and sinusoidal lining cells in the centrilobular areas 5 days after intraperitoneal administration. 2. In the D-galactosamine treated rats, spotty necrosis with inflammatory cell infiltration throughout the lobule, and swelling and increment of Kupffer cells were appeared 2 days after intraperitoneal administration. 3. There were slightly increased thickness of renal glomerular basement membrane and widening of the mesangeal matrix in dimethylnitrosamine-treated rats, 14 days after intraperitoneal administration, but no pathological changes were observed in glomerular basement membrane and mesangeal cells in D-galactosamine treated rats. 4. There were glomerular IgA deposition after a single dose administration of dimethylnitrosamine. Slight deposits of IgA appeared 2 days after administration, In 5 days after administration, the deposits gradually intensified and peaked at 14 days after administration, However in the D-galactosamine-treated rats, only slight deposits of IgA appeared at days 7 and 14 There were no depositions of IgG in the dimethylnitrosamine and D-galactosamine treated rats. 5. These results suggest that dysfunction of the hepatocytes and Kupffer cells contribute to glomerular IgA deposition.

韓國語와 英語의 對照 硏究와 그 敎育的 效用

全在昊,金宗澤,朴英壽 慶北大學校 人文科學硏究所 1986 人文 科學 Vol.2 No.-

다형성 선종에서의 근상피세포에 대한 병리학적 연구

최종범,임성철,전호종,서재홍 대한병리학회 1992 Journal of Pathology and Translational Medicine Vol.26 No.2

악성 섬유성 조직구종의 기원에 관한 면역조직화학적 및 초미세형태학적 연구

전호종,임성철,강종식,김일,황호원 朝鮮大學校 附設 醫學硏究所 1991 The Medical Journal of Chosun University Vol.15 No.1

Malignant fibrous histiocytoma(MFH) was first terminologically introduced in 1963 to refer to a group malignant soft tissue tumors characterized by a stonform growth pattern and these tumors are a oup of sarcomas composed of cells morphologically resembling fibroblast and histiocvte. The histogeisis of MFH is still controversial, but a more complete appreciation of it's morphogenesis has been ovided by tissue culture and ultrastructural studies. In the present study, ultrastructural and immunohistochemical studies of seven cases of MFH disclosee maturation and development of principal types of cells constituting MFH and immunohistochemical actions to investigate the histogenesis of malignant fibrous histiocytoma. The results obtained were as follows. Malignant fibrous histiocytoma composed of different portions of fibroblast-like cells, histiocyte-like cells, cells intermediate between histiocyte-and fibroblast-like cells, multinucleated giant cells, undif ferentiated cells, xanthomatous cells and myofibroblast. The principal cell types of malignant fibrous histiocytoma were fibroblast-like, histiocyte-like, intermediate (fibrohistiocytoid) and undifferentiated cell. There were cells bearing variable stages of differentiation along the fibroblastic and histiocytic lines from undifferentiated cells. 2. There was no difference in cellular composition ultrastructurally between storiform-pleomorphic, myxoid and inflammatory subtypes. 3. Junctional complexes were shown in fibroblast-like, histiocyte-like cells, intermediate cell and myofibroblasts. Long desmosomes were observed in histiocyte-like cells, intermediated cells and myofibroblasts, Paired subplasmalemmal densities were also shown in fibroblast-like cells and. intermediate forms. 4. Immunohistochemical reactions revealed strong staining reactions for α1-antitrymotrypsin in histiocyte=like cells and multmucleated giant cells. Vimentin was reactive for fibroblast-like cells, histsiocyte-like cells and multinucleated giant cells. However, no evidence of staining reactions for α1-antitrypsin, a1-antichymotrypsin, vimentin, lysozyme in the cells of early stage of differentiation along the fibroblast and histiocyte-like cells from the undifferentiated cells. 5. In conclusion it is suggested that malignant fibrous histiocytoma may be considered a primitive mesenchymal tumors originating from undifferentiated cells.