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Jong Hyun Moon,Jang Jin,C. R. Lee,Choong Hoon Lee,J. J. Kim,Kyu Chang Park,Sung Gu Kang,Sung Hoon Lim,Woo Kyung Bae 한국물리학회 2004 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.45 No.2
We have grown carbon nanotubes (CNTs) in the gate holes for triode-type FEA (eld-emitter array) by plasma-enhanced chemical vapor deposition (PECVD) by varying the growth temperature between 400 C and 580 C. By applying plasma pretreatment onto catalyst metal, we have developed the low-temperature growth of CNTs by PECVD for triode-type FEA. The activation energy for the growth rate was found to be 0.47 eV, much less than that by chemical vapor deposition (1.2 1.5 eV). Plasma post-treatment on the grown CNTs can control the length of CNTs in the gate hole, resulting in enhanced eld-emission characterization. Uniform light emission from the triode-type eld emitter could be realized by optimizing the CNT length through the plasma treatment time.
Yim, Jong Hyuk,Joe, Sung-yoon,Pang, Christina,Lee, Kyung Moon,Jeong, Huiseong,Park, Ji-Yong,Ahn, Yeong Hwan,de Mello, John C.,Lee, Soonil American Chemical Society 2014 ACS NANO Vol.8 No.3
<P>We report the fabrication of efficient indium–tin–oxide-free organic solar cells based on poly(3-hexylthiophene-2,5-diyl):[6,6]-phenyl-C61-butyric acid methyl ester (P3HT:PCBM). All layers of the devices from the lowermost silver nanowire cathode to the uppermost conducting polymer anode are deposited from solution and processed at plastic-compatible temperatures <200 °C. Owing to the absence of an opaque metal electrode, the devices are semitransparent with potential applications in power-generating windows and tandem-cells. The measured power conversion efficiencies (PCEs) of 2.3 and 2.0% under cathode- and anode-side illumination, respectively, match previously reported PCE values for equivalent semitransparent organic solar cells using indium tin oxide.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2014/ancac3.2014.8.issue-3/nn406672n/production/images/medium/nn-2013-06672n_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn406672n'>ACS Electronic Supporting Info</A></P>
박병권(Byung-Kwon Park),임종환(Jong-Hwan Lim),황윤환(Youn-Hwan Hwang),김명석(Myung-Seok Kim),송인배(In-Bae Song),이홍기(Hong-Gee Lee),한성진(Sung-Jin Han),황미현(Mi-Hyun Hwang),김종우(Jong-Woo Kim),이만휘(Man-Hee Rhee),박승춘(Seong-C 한국독성학회 2006 Toxicological Research Vol.22 No.4
This study was carried out to investigate the acute toxicity of surfactin C in mice. Surfactin C was administered orally at does of 0, 381, 610, 977, 1562 and 2500 ㎎/㎏. Number of deaths, clinical signs, body weights, feed and water consumptions, and biochemical examinations were investigated for 14 days after single oral administration of surfactin C. LD?? value was over 2500 ㎎/㎏ in mice. In addition, no differences were found between control and treated groups in clinical signs, body weight gains, hematology, serum chemistry, feed and water consumptions. The results indicate that surfactin C did not show any toxic effects at 2500 ㎎/㎏ in mice.
KIM, DONG I.,KIM, EUN H.,BYUN, JONG C.,CHOI, JONG H.,NA, HUN G.,PARK, YU C. 濟州大學校 基礎科學硏究所 2002 基礎科學硏究 Vol.15 No.2
The benzoylated asymmetrical nickel(Ⅱ) complexes, 2,4,9,11 -tetramethyl-3,10-dibenzoyl- 1,5,8,12-([ 14]-Xbenzo)tetraazacyclotetradecinato(2-)nickel(II) (A_(1-4)) and 2,4,10,12-tetra- methyl3, l1-dibenzoyl-l,5,9,13-([15]-Xbenzo)tetraazacyclotetradecinato(2-)nickel(II) (B_(1-4)), wherein X=CH3 (A_(l) and B_(1)), H (A_(2) and B_(2)), C1 (A3 and B_(3)) and NO_(2) (A_(4) and B_(4)), have been synthesized and characterized by analysis, IR, electronic, ^(1)H- and ^(13)C-NMR spectra. An intense IR band due to C=O stretching is present in the range 1630-1650cm^(-1) upon benzoylation. Electronic spectra show bands at 375-390nm with ^(ε)max = 10000- 26000 M^(-1)cm^(-1) due to π → π^(*) transitions of macrocycles and at 500-550 nm with (ε)max = 10000- 5000 M^(-1)cm^(-1) attributable to LMCT for each of the complexes. The proton peaks of methine sites in the NMR spectra disappear on benzoylation. Results of the carbon-13 NMR spectra are compatible with those of the proton NMR. Cyclic voltammograms of the complexes in acetonitrile exhibit two successive and reversible (irreversible in DMSO) oxidation peaks for the macrocycle (Mc → Mc^(+) and Mc^(+) →Mc^(2+)) in the ranges +0.31-+0.51 and +0.60-+0.84V, respectively. In the reduction area, a reversible wave is followed by reduction of metal {Ni(II) → Ni(Ⅰ) at around -2.32V}. Unlike analogous complexes without the benzoyl group, those compounds are not electropolymerized by cyclic voltammetry.
Cho, Jung Sun,Youn, Ho-Joong,Her, Sung-Ho,Park, Maen Won,Kim, Chan Joon,Park, Gyung-Min,Jeong, Myung Ho,Cho, Jae Yeong,Ahn, Youngkeun,Kim, Kye Hun,Park, Jong Chun,Seung, Ki Bae,Cho, Myeong Chan,Kim, C The Korean Academy of Medical Sciences 2015 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.30 No.7
<P>The prognostic value of the left ventricle ejection fraction (LVEF) after acute myocardial infarction (AMI) has been questioned even though it is an accurate marker of left ventricle (LV) systolic dysfunction. This study aimed to examine the prognostic impact of LVEF in patients with AMI with or without high-grade mitral regurgitation (MR). A total of 15,097 patients with AMI who received echocardiography were registered in the Korean Acute Myocardial Infarction Registry (KAMIR) between January 2005 and July 2011. Patients with low-grade MR (grades 0-2) and high-grade MR (grades 3-4) were divided into the following two sub-groups according to LVEF: LVEF ≤ 40% (n = 2,422 and 197, respectively) and LVEF > 40% (n = 12,252 and 226, respectively). The primary endpoints were major adverse cardiac events (MACE), cardiac death, and all-cause death during the first year after registration. Independent predictors of mortality in the multivariate analysis in AMI patients with low-grade MR were age ≥ 75 yr, Killip class ≥ III, N-terminal pro-B-type natriuretic peptide > 4,000 pg/mL, high-sensitivity C-reactive protein ≥ 2.59 mg/L, LVEF ≤ 40%, estimated glomerular filtration rate (eGFR), and percutaneous coronary intervention (PCI). However, PCI was an independent predictor in AMI patients with high-grade MR. No differences in primary endpoints between AMI patients with high-grade MR (grades 3-4) and EF ≤ 40% or EF > 40% were noted. MR is a predictor of a poor outcome regardless of ejection fraction. LVEF is an inadequate method to evaluate contractile function of the ischemic heart in the face of significant MR.</P>
Min Young Kim,Kyung Suk Song,Gun Ho Park,Hyun Woo Kim,Jin Hong Park,Jun Sung Kim,Hwa Jin,Kook Jong Eu,Hyun Sun Cho,Gami Kang,Chanhee Chae,Yoon Shin Kim,Young Chul Kim,Hae Yeong Kim,George Beck,Nancy C 한국독성학회 2004 Toxicological Research Vol.20 No.1
Changes in cell cycle control in the lungs and liver of the B6C3F1 mice (20 males per each group) exposed to ozone (0.5 ppm), 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK, 1.0 mg/kg), and dibutyl phthalate (DBP, 5,000 ppm) after 52 weeks were examined through Western, Northern blot, and immunohistochemistry based on alterations in protein expression levels of G1/S checkpoints (cyclin D1, cyclin E, and PCNA), G2/M checkpoints (cyclin B1, cyclin G, and cyclin A), negative regulators (p53, p21, GADD45, and p27), and positive regulator (mdm2). Expression levels of cyclins D1, E, G, PCNA, mutant p53, and mdm2 proteins were higher in the lungs<br/> and livers treated with combination of toxicants than in those treated with ozone only. Expression levels of the wild-type and mutant p53, p21, GADD45, p27, and mdm2 proteins and mRNAs were<br/> higher in toxicant-treated groups than those of the control. Immunohistochemical analysis revealed staining intensities of the PCNA, cyclin D1, c-myc and mdm2 protein- treated lungs and livers were stronger than those of the control group. Our results showed that combined treatment of ozone with NNK/DBP altered the cell cycle control through instability of the wild-type p53 gene. Such pivotal p53-mediated cell cycle alterations may be responsible for the toxicity observed under our experimental condition. These results may be applied to risk assessment of mixture-induced toxicity.
Park, Byung-Gook,Choi, Byung Yong,Choi, Woo Young,Lee, Yong Kyu,Lee, Jong Duk,Shin, Hyungcheol,Sung, Suk-Kang,Kim, Tae-Yong,Cho, Eun Suk,Cho, Byung Kyu,Bai, Keun Hee,Kim, Dong-Dae,Kim, Dong-Won,Lee, C The Japan Society of Applied Physics 2005 Japanese journal of applied physics Vol.44 No.37
<P>Thanks to the combination of damascene gate and outer poly-Si sidewall spacer process, we have successfully fabricated twin silicon–oxide–nitride–oxide–silicon (SONOS) memory (TSM) transistors with 20-nm twin nitride storage nodes under an 80-nm gate. In terms of device manufacturability, the damascene gate process makes it possible to realize physically separated structure and the outer poly-Si sidewall spacer scheme contributes to realization of 20-nm long nitride storage node. Compared with conventional SONOS transistor, the fabricated TSM transistor maintains its threshold voltage margin between the forward and reverse reads down to 80-nm long gate. The TSM transistor also shows stable and reliable characteristics: up to 10<SUP>5</SUP> program/erase cycles endurance and fairly good bake retention at 150°C.</P>
ISO 9712에 따른 비파괴검사 기술자 자격인정 및 인증제도 수립을 위한 조사연구(Ⅰ)
이종포,박은수,한치현,하기수,장영권 한국비파괴검사학회 2003 학술대회 논문집 Vol.- No.1
비파괴검사 기술자에 대한 자격인정 및 인증에 관한 국제 표준인 ISO 9712가 1991년 제정되고 이후 개정판이 계속 이어지고 있다. 세계 각국은 자국의 비파괴검사 기술자 자격인정 및 인증제도를 국제 기준인 ISO 9712에 부합되게 고치거나 아직 자국에 그런 규정이나 제도가 없었던 나라들에서는 국제 기준에 맞는 제도를 수립해가고 있다. 우리나라는 국제 기준이 제정되기 이전에 국가기술자격법에 의한 비파괴검사 자격제도를 수립하였고 이후 국제 환경의 변화와 국제기준의 제정에 따라 자격기본법을 추가로 제정하여 시행하고 있으나 ISO 9712와는 거리가 멀어 비파괴검사 기술자 자격은 국가간에 상호 인정이 어렵도록 되어 있다. 한국 비파괴검사학회 표준화 위원회에서는 이와 같은 현실을 감안하여 ISO 9712에 따른 자격인정 및 인증 제도 수립을 위하여 ISO 9712와 관련된 국제 기준과 각국의 기준을 조사 분석하고, 국내의 관련 규정과 비교 검토함으로써, 국내에 새로운 자격제도 수립이나 자격제도 변경의 타당성을 조사 분석하였다. 본 원고에서는 1차년도의 조사 분석 연구결과를 여기에 요약 제시한다.
Juha Song,C-Yoon Kim,Seo-Na Chang,Tamer Said Abdelkader,Juhee Han,Tae-Hyun Kim,Hanseul Oh,Ji Min Lee,Dong-Su Kim,Jong-Taek Kim,Hong-Shik Oh,Moonsuk Hur,Jae-Hwa Suh,Jae-Hak Park 대한기생충학열대의학회 2015 The Korean Journal of Parasitology Vol.53 No.6
In order to examine the prevalence of Cryptosporidium infection in wild rodents and insectivores of South Korea and to assess their potential role as a source of human cryptosporidiosis, a total of 199 wild rodents and insectivore specimens were collected from 10 regions of South Korea and screened for Cryptosporidium infection over a period of 2 years (2012-2013). A nested-PCR amplification of Cryptosporidium oocyst wall protein (COWP) gene fragment revealed an overall prevalence of 34.2% (68/199). The sequence analysis of 18S rRNA gene locus of Cryptosporidium was performed from the fecal and cecum samples that tested positive by COWP amplification PCR. As a result, we identified 4 species/genotypes; chipmunk genotype I, cervine genotype I, C. muris, and a new genotype which is closely related to the bear genotype. The new genotype isolated from 12 Apodemus agrarius and 2 Apodemus chejuensis was not previously identified as known species or genotype, and therefore, it is supposed to be a novel genotype. In addition, the host spectrum of Cryptosporidium was extended to A. agrarius and Crosidura lasiura, which had not been reported before. In this study, we found that the Korean wild rodents and insectivores were infected with various Cryptosporidium spp. with large intra-genotypic variationa, indicating that they may function as potential reservoirs transmitting zoonotic Cryptosporidium to livestock and humans.
Automatic extension of Gene Ontology with flexible identification of candidate terms
Lee, Jin-Bok,Kim, Jung-jae,Park, Jong C. Oxford University Press 2006 Bioinformatics Vol.22 No.6
<P><B>Motivation:</B> Gene Ontology (GO) has been manually developed to provide a controlled vocabulary for gene product attributes. It continues to evolve with new concepts that are compiled mostly from existing concepts in a compositional way. If we consider the relatively slow growth rate of GO in the face of the fast accumulation of the biological data, it is much desirable to provide an automatic means for predicting new concepts from the existing ones.</P><P><B>Results:</B> We present a novel method that predicts more detailed concepts by utilizing syntactic relations among the existing concepts. We propose a validation measure for the automatically predicted concepts by matching the concepts to biomedical articles. We also suggest how to find a suitable direction for the extension of a constantly growing ontology such as GO.</P><P><B>Availability:</B> http://autogo.biopathway.org</P><P><B>Contact:</B> park@nlp.kaist.ac.kr</P><P><B>Supplementary information:</B> Supplementary materials are available at <I>Bioinformatics</I> online.</P>