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Jeremy C. DeGuzman,Tarlac State University,Kyla Niicole G. Cruz,Jiyoung Lee 국제인문사회연구학회 2022 Studies on Humanities and Social Sciences (SHSC) Vol.4 No.1
The Relationship Between Self-confidence and Academic Commitment of AB-ELS Students in Learning Korean Language in an Online Class Setting Jeremy C. DeGuzman,* Kim M. andrea Reyes,** Kyla Niicole G. Cruz,*** & Jiyoung Lee**** Abstract: The purpose of this study is to investigate the Self-confidence and Academic Commitment of students learning Korean online. The subjects of this study were 86 4th year students of AB ELS who participated in online Korean language classes. In this study, analysis data were collected through an online questionnaire of self-confidence and academic commitment. For analysis, using SPSS 23.0, descriptive statistics and correlation analysis were performed. The research results are as follows. First, the students’ self-confidence was found to be neither agree nor disagree. Second, students’ academic commitment was slightly disagreed. Third, it was found that there was a significant positive correlation between students’ self-confidence and academic commitment. Based on the results of this study, methods to enhance the academic commitment of students learning Korean online were discussed. Key Words: AB English Language Studies Students, Academic Commitment, Correlation, Foreign Language Learning, Korean language, Online Classroom, Self-confidence □ Received: June 1, 2022, Revised: June 28, 2022, Accepted: June 30, 2022 * First Author, College of Arts and Social Sciences, Tarlac State University, Philippines, Student ** Co-author 1, College of Arts and Social Sciences, Tarlac State University, Philippines, Student *** Co-author 2, College of Arts and Social Sciences, Tarlac State University, Philippines, Student **** Corresponding Author, College of Arts and Social Sciences, Tarlac State University, Philippines, Lecturer The Relationship Between Self-confidence and Academic Commitment of AB-ELS Students in Learning Korean Language in an Online Class Setting Jeremy C. DeGuzman,* Kim M. andrea Reyes,** Kyla Niicole G. Cruz,*** & Jiyoung Lee**** Abstract: The purpose of this study is to investigate the Self-confidence and Academic Commitment of students learning Korean online. The subjects of this study were 86 4th year students of AB ELS who participated in online Korean language classes. In this study, analysis data were collected through an online questionnaire of self-confidence and academic commitment. For analysis, using SPSS 23.0, descriptive statistics and correlation analysis were performed. The research results are as follows. First, the students’ self-confidence was found to be neither agree nor disagree. Second, students’ academic commitment was slightly disagreed. Third, it was found that there was a significant positive correlation between students’ self-confidence and academic commitment. Based on the results of this study, methods to enhance the academic commitment of students learning Korean online were discussed. Key Words: AB English Language Studies Students, Academic Commitment, Correlation, Foreign Language Learning, Korean language, Online Classroom, Self-confidence □ Received: June 1, 2022, Revised: June 28, 2022, Accepted: June 30, 2022 * First Author, College of Arts and Social Sciences, Tarlac State University, Philippines, Student ** Co-author 1, College of Arts and Social Sciences, Tarlac State University, Philippines, Student *** Co-author 2, College of Arts and Social Sciences, Tarlac State University, Philippines, Student **** Corresponding Author, College of Arts and Social Sciences, Tarlac State University, Philippines, Lecturer
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Jiyoung Kim,Suk Kyun Hong,Jae-Yoon Kim,Jaewon Lee,Hyun Hwa Choi,Sola Lee,Su young Hong,Jeong-Moo Lee,YoungRok Choi,Nam-Joon Yi,Kwang-Woong Lee,Kyung-Suk Suh 대한외과학회 2023 Annals of Surgical Treatment and Research(ASRT) Vol.105 No.1
Purpose: Total necrosis of hepatocellular carcinoma (HCC) achieved via locoregional treatment (LRT) is considered to indicate a lack of tumor viability. Nonetheless, there is insufficient evidence of recurrence after liver transplantation (LT) in patients with such a status. The aim of this study was to investigate the prognosis of patients diagnosed with totally necrotic nodules upon explant hepatectomy after LT. Methods: We conducted a retrospective study of patients diagnosed with totally necrotic nodules after LT for HCC. A total of 165 patients with HCC who underwent living- or deceased-donor LT from 2000 to 2020 in our hospital were included. Results: A total of 5 patients (3.0%) exhibited HCC recurrence during a median follow-up of 84 months (range, 4–243 months) after LT. The 5-year overall and recurrence-free survival rates of these patients were 92.8% and 92.2%, respectively. Four patients in the HCC-recurrence group (80.0%) died even after further treatment, including transarterial chemoembolization, surgery, and systemic treatment. Both univariate and multivariate analyses of clinicopathological factors identified a maximum diameter of the totally necrotic nodules of >5 cm as the only factor associated with tumor recurrence following LT (P = 0.005 and P = 0.009, respectively). Conclusion: Total necrosis of HCC via LRT yielded excellent survival outcomes for patients undergoing LT. Nevertheless, patients with large tumors should be considered at high risk of recurrence after LT, suggesting the need for their active surveillance during the follow-up period.
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Lee, Jun Ho,Suh, Jae Hee,Choi, Soo Youn,Kang, Hyun Je,Lee, Hwan Hee,Ye, Byeong Jin,Lee, Gap Ryol,Jung, Seok Won,Kim, Chang Jae,Lee-Kwon, Whaseon,Park, Jiyoung,Myung, Kyungjae,Park, Neung Hwa,Kwon, Hyu BMJ Publishing Group 2019 Gut: journal of the British Society of Gastroenter Vol.68 No.2
<P><B>Objectives</B></P><P>Hepatocellular carcinoma (HCC) is a common cancer with high rate of recurrence and mortality. Diverse aetiological agents and wide heterogeneity in individual tumours impede effective and personalised treatment. Tonicity-responsive enhancer-binding protein (TonEBP) is a transcriptional cofactor for the expression of proinflammatory genes. Although inflammation is intimately associated with the pathogenesis of HCC, the role of TonEBP is unknown. We aimed to identify function of TonEBP in HCC.</P><P><B>Design</B></P><P>Tumours with surrounding hepatic tissues were obtained from 296 patients with HCC who received completion resection. TonEBP expression was analysed by quantitative reverse transcription–quantitative real-time PCR (RT-PCR) and immunohfistochemical analyses of tissue microarrays. Mice with TonEBP haplodeficiency, and hepatocyte-specific and myeloid-specific TonEBP deletion were used along with HCC and hepatocyte cell lines.</P><P><B>Results</B></P><P>TonEBP expression is higher in tumours than in adjacent non-tumour tissues in 92.6% of patients with HCC regardless of aetiology associated. The TonEBP expression in tumours and adjacent non-tumour tissues predicts recurrence, metastasis and death in multivariate analyses. TonEBP drives the expression of cyclo-oxygenase-2 (COX-2) by stimulating the promoter. In mouse models of HCC, three common sites of TonEBP action in response to diverse aetiological agents leading to tumourigenesis and tumour growth were found: cell injury and inflammation, induction by oxidative stress and stimulation of the COX-2 promoter.</P><P><B>Conclusions</B></P><P>TonEBP is a key component of the common pathway in tumourigenesis and tumour progression of HCC in response to diverse aetiological insults. TonEBP is involved in multiple steps along the pathway, rendering it an attractive therapeutic target as well as a prognostic biomarker.</P>
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Lee Jiyoung,Lee Mi-Young,Lee Jina,Jang Euijin,Bae Seongman,Jung Jiwon,Kim Min Jae,Chong Young Pil,Won Hye-Sung,Jung Euiseok,Kim Sung-Han 대한감염학회 2023 Infection and Chemotherapy Vol.55 No.3
Background: There are limited data on the clinical characteristics and the vertical transmission rate of pregnant women with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and their neonates in Korea. Materials and Methods: Pregnant women who tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection were retrospectively reviewed in Asan Medical Center from September 1, 2020, to April 26, 2022. All neonates and infected women underwent a polymerase chain reaction test for severe acute respiratory syndrome corona virus 2 within 24 hours of birth and at 48-hour interval if they stayed in the hospital. Results: A total of 60 pregnant women gave birth by cesarean section (n = 40, 66.7%) or vaginal delivery (n = 20, 33.3%). Among them, 3 women gave birth to twins. Delivery occurred, on average, at 38+2 weeks (± 2+0) of gestational age, and 9 patients (15.0%) had underlying diseases. Of these 60 patients, 9 (15.0%) received coronavirus disease 2019 vaccinations. Pneumonia was confirmed by a chest radiograph in 7 patients (11.7%), and 2 patients (3.3%) required supplemental oxygen therapy, both of whom eventually recovered. The mean birthweight of the neonates was 3,137 g (± 557.6). Further, 8 neonates (12.7%) were of low-birth weight (< 2,500 g), and 11 neonates (17.5%) were preterm (<37 weeks of gestation). Apgar score was median 8 (8 - 9) at 1 minute and 9 (9 – 9.5) at 5 minutes. Four neonates (6.3%) required invasive mechanical ventilation. All neonates had negative SARS-CoV-2 test results. Therefore, there was no vertical transmission in 63 of the neonates (0%, 95% confidence interval [CI]: 0 - 6) Conclusion: Pregnant Korean women with SARS-CoV-2-infection had favorable obstetric outcomes, and the risk of vertical transmission to their neonates was low. Managing the infection risks of pregnant women and their neonates during the coronavirus disease 2019 pandemic are required.
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The Effects of Acupotomy Therapy on Carpal Tunnel Syndrome: A Report of 4 Cases
Lee, Seongjin,Cha, Eunhye,Yang, Muhak,Lee, Jongdeok,Lee, Jiyoung,Lee, Sojin,Kim, Deokho,Kim, Sungchul Korean AcupunctureMoxibustion Medicine Society 2018 Korean Journal of Acupuncture Vol.35 No.1
The aim of this report was to show the effects of acupotomy in patients with carpal tunnel syndrome. Four patients were treated with acupotomy twice. Visual analogue scale (VAS), Tinel's sign, Phalen's test, Boston carpal tunnel syndrome questionnaire (BCTQ), muscular strength test, and a cross-sectional area of median nerve was measured using ultrasound before and after treatment. In all 4 cases, the VAS score, BCTQ score and cross-sectional area of median nerve, all decreased and muscular strength test score increased. Tinel's sign and the Phalen's test changed from a positive to a negative in most cases. This report shows that acupotomy is an effective treatment for carpal tunnel syndrome. Further larger are needed to fully evaluate the beneficial effects of this treatment.
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Lee, Changhu,Kim, Min,Lee, Jun Ho,Oh, Jiyoung,Shin, Hyun‐,Hee,Lee, Sang Min,Scherer, Philipp E,Kwon, Hyug Moo,Choi, Jang Hyun,Park, Jiyoung John Wiley Sons, Ltd. 2019 The Journal of pathology Vol.247 No.1
<P><B>Abstract</B></P><P>Extracellular matrix dysregulation is associated with chronic liver disease. CollagenVI‐alpha3 chain (COL6A3) is a biomarker for hepatic fibrosis and poor prognosis of hepatocellular carcinoma (HCC), but its function in liver pathology remains unknown. High levels of COL6A3 and its cleaved product, endotrophin (ETP) in tumor‐neighboring regions are strongly associated with poor prognosis in HCC patients. Here, we report that the high levels of ETP in injured hepatocytes induce JNK‐dependent hepatocyte apoptosis and activate nonparenchymal cells to lead further activation of hepatic inflammation, fibrosis, and apoptosis. Nevertheless ETP <I>per se</I> showed limited phenotypic changes in normal liver tissues. Furthermore, inhibition of ETP activity by utilizing neutralizing antibodies efficiently suppressed the pathological consequences in chronic liver diseases. Our results implicate ETP mechanistically as a crucial mediator in reciprocal interactions among various hepatic cell populations in the pathogenesis of chronic liver disease, and it could be a promising therapeutic target particularly in individuals with high local levels of COL6A3. Copyright © 2018 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.</P>
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Lee, Dong Eun,Shin, Bong Jik,Hur, Haeng Jeon,Kim, Jong Hun,Kim, Jiyoung,Kang, Nam Joo,Kim, Dae Ok,Lee, Chang Yong,Lee, Ki Won,Lee, Hyong Joo Cambridge University Press 2010 The British journal of nutrition Vol.104 No.2
<P>We evaluated the effects of the two main kiwifruit cultivars (gold kiwifruit (GOK) and green kiwifruit (GRK)) and their active phenolic compound, quercetin, on H2O2-induced inhibition of gap-junction intercellular communication (GJIC) in WB-F344 rat liver epithelial cells. We found that both GOK and GRK protect WB-F344 cells from H2O2-induced inhibition of GJIC. The extracellular signal-regulated protein kinase 1/2 (ERK1/2)-connexin 43 (Cx43) signalling pathway is crucial for the regulation of GJIC, and both GOK and GRK blocked the H2O2-induced phosphorylation of Cx43 and ERK1/2 in WB-F344 cells. Quercetin alone attenuated the H2O2-mediated ERK1/2-Cx43 signalling pathway and consequently reversed H2O2-mediated inhibition of GJIC in WB-F344 cells. A free radical-scavenging assay using 1,1-diphenyl-2-picrylhydrazyl showed that the scavenging activity of quercetin was higher than that of a synthetic antioxidant, butylated hydroxytoluene, per mol, suggesting that the chemopreventive effect of quercetin on H2O2-mediated inhibition of ERK1/2-Cx43 signalling and GJIC may be mediated through its free radical-scavenging activity. Since the carcinogenicity of reactive oxygen species such as H2O2 is attributable to the inhibition of GJIC, GOK, GRK and quercetin may have chemopreventive potential by preventing the inhibition of GJIC.</P>
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The Influence of Face Shields on the Quality of Colonoscopy in the Era of the COVID-19 Pandemic
Lee Jin Wook,Lee Hyo Jeong,Kim Dae Sung,Yoon Jiyoung,Hong Seung Wook,Hwang Ha Won,Lee Jong-Soo,Kim Gwang-Un,Lee Sinwon,Choe Jaewon,Park Jin Hwa,Yang Dong-Hoon,Byeon Jeong-Sik 거트앤리버 소화기연관학회협의회 2022 Gut and Liver Vol.16 No.3
Background/Aims: The worldwide coronavirus disease 2019 pandemic has led endoscopists to use personal protective equipment (PPE) for infection prevention. This study aimed to investigate whether wearing a face shield as PPE affects the quality of colonoscopy. Methods: We reviewed the medical records and colonoscopy findings of patients who underwent colonoscopies at Asan Medical Center, Korea from March 10 to May 31, 2020. The colonoscopies in this study were performed by five gastroenterology fellows and four expert endoscopists. We compared colonoscopy quality indicators, such as withdrawal time, adenoma detection rate (ADR), mean number of adenomas per colonoscopy (APC), polypectomy time, and polypectomy adverse events, both before and after face shields were added as PPE on April 13, 2020. Results: Of the 1,344 colonoscopies analyzed, 715 and 629 were performed before and after the introduction of face shields, respectively. The median withdrawal time was similar between the face shield and no-face shield groups (8.72 minutes vs 8.68 minutes, p=0.816), as was the ADR (41.5% vs 39.8%, p=0.605) and APC (0.72 vs 0.77, p=0.510). Polypectomy-associated quality indicators, such as polypectomy time and polypectomy adverse events were also not different between the groups. Quality indicators were not different between the face shield and no-face shield groups of gastroenterology fellows, or of expert endoscopists. Conclusions: Colonoscopy performance was not unfavorably affected by the use of a face shield. PPE, including face shields, can be recommended without a concern about colonoscopy quality deterioration.
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