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南海岸地方의 櫛文土器 硏究(1) : 釜山·慶南地方 晩期櫛文土器의 檢討
鄭澄元 부산대사학회 1982 역사와 세계 Vol.- No.6
Of 20 sites in southern coast region known as Korean neolithic remains up to present, 11 sites of them alone have yieled the comb-pattern potteries. The caracteristics of the late comb-pattern pottries which have been excavated in southern coast region are very similar to ones of the precious times in terms of the type, paste, colour, thickness and the basic technique of manufacturing, but many changes occurred such as retrogradation of the carving technique, simple and unifying decoration, diminution of decoration on the surface of the pottery, and the steady increase of noncarving potteries and so on. In a word, the former indicates the traditional factors remain intact, and the latter just does the transmutation of them. In addition to the general characristics as stated above, the visible ones on the late comb-pattern potteries excavated in the southern coast region are sandy paste, double mouth rim and horizontal bands of oblique. The sandy paste and degenerate horizontal bands of oblique may have resulted from the western coast region, and the double mouth rim may appear in the southern coast itself. And the characteristics as given above are believed that the comb-pattern potteries themselves changed and degnerated, there being no possibility of being affected by the plain coarse potteries, especially in terms of what the factors of plain coarse potteries have not been found in the late comb-pattern potteries.
장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4
Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.
( Jin Won Hyun ),( Ji Won Cha ),( Mei Jing Piao ),( Ki Cheon Kim ),( Cheng Wen Yao ),( Jian Zheng ),( Seong Min Kim ),( Chang Lim Hyun ),( Yong Seok Ahn ) 한국응용약물학회 2014 Biomolecules & Therapeutics(구 응용약물학회지) Vol.22 No.2
We investigated the protective effects of chlorogenic acid (CGA), a polyphenol compound, on oxidative damage induced by UVBexposure on human HaCaT cells. In a cell-free system, CGA scavenged 1,1-diphenyl-2-picrylhydrazyl radicals, superoxide anions,hydroxyl radicals, and intracellular reactive oxygen species (ROS) generated by hydrogen peroxide and ultraviolet B (UVB). Furthermore, CGA absorbed electromagnetic radiation in the UVB range (280-320 nm). UVB exposure resulted in damage to cellularDNA, as demonstrated in a comet assay; pre-treatment of cells with CGA prior to UVB irradiation prevented DNA damage andincreased cell viability. Furthermore, CGA pre-treatment prevented or ameliorated apoptosis-related changes in UVB-exposedcells, including the formation of apoptotic bodies, disruption of mitochondrial membrane potential, and alterations in the levelsof the apoptosis-related proteins Bcl-2, Bax, and caspase-3. Our findings suggest that CGA protects cells from oxidative stressinduced by UVB radiation.
Lu, Jing Nan,Lee, Won Sup,Yun, Jeong Won,Kim, Min Jeong,Kim, Hye Jung,Kim, Dong Chul,Jeong, Jae-Hoon,Choi, Yung Hyun,Kim, Gon-Sup,Ryu, Chung Ho,Shin, Sung Chul Hindawi Publishing Corporation 2013 Evidence-based Complementary and Alternative Medic Vol.2013 No.-
<P>Recently we have demonstrated that anthocyanins from fruits of <I>Vitis coignetiae</I> Pulliat (AIMs) have anticancer effects. Here, we investigate the effects of AIMs on cell proliferation and invasion as well as epithelial-mesenchymal transition (EMT) which have been linked to cancer metastasis in human uterine cervical cancer HeLa cells. AIMs inhibited the invasion of HeLa cells in a dose-dependent manner. AIMs inhibited MMP-9 expression in a dose-dependent manner. AIMs inhibited the motility of HeLa cells in a wound healing test. AIMs still suppressed NF-<I><I>κ</I></I>B activation induced by TNF. AIMs also inhibited EMT in HeLa cells. AIMs suppressed vimentin, N-cadherin, and <I>β</I>-catenin expression and induced E-cadherin. AIMs also suppressed expression of <I>β</I>-catenin and Snail, which was regulated by GSK-3. These effects of AIMs were also limited in the HeLa cells treated with TNF. In conclusion, this study indicates that AIMs have anticancer effects by suppressing NF-<I><I>κ</I></I>B-regulated genes and EMT, which relates to suppression of I<I><I>κ</I></I>B<I><I>α</I></I> phosphorylation and GSK-3 activity, respectively. However, the effects of AIMs were attenuated in the TNF-high condition.</P>