Goldman's Algorithm을 이용한 비외상성 흉통 환자의 분석

조석진,유진현,김찬웅,어은경,정구영 대한응급의학회 1999 대한응급의학회지 Vol.10 No.4

Back ground : It is important to evaluate the patient presenting with non-traumatic chest pain in emergency department, and it is also difficult to classify appropriately. The purpose of this study is to predict probability of acute myocardial infarction(AMI) and assess the group for low probability of AMI that is target for observation-unit of chest pain in emergency department. Methods : A prospective, clinical study was performed from March 1998 to August 1998 at the department of emergency medicine, Ewha Womans University Mokdong hospital. We classified high-probability group and low-probability group of AMI according to Goldman's algorithm and then compared with the final diagnosis. Results : The study included 218 patients. 84 patients(39%) was the high-probability group and 134 patients(61%) was the low-probability group of AMI. As compared with final diagnosis, AMI was 47 patients(56%) among the high-probability group and 1 patient(0.7%) among the low-probability group. We observed sensitivity of 98%, specificity of 78% in predicting AMI. Conclusion : The classification according to Goldman's algorithm may be useful predictor of AMI and improve triage for emergency department patients with chest pain. It is also helpful for management of observation-unit of chest pain in emergency department.

부산 서구 저탄소 녹색도시사업을 통한 지역환경 개선 및 활성화 방안 연구

정숙진, 윤성환, 우신구 신라대학교 부산학연구센터 2012 부산연구 Vol.10 No.-

전 세계의 환경문제인 기후변화에 적극적으로 대응하기 위해 새로운 국가 비전인 저탄소 녹색도시을 견인할 수 있는 지역·권역별 녹색도시화 특성화 방안을 제시함으로서 기후변화에 대응할 수 있는 방안을 모색하고자 한다. 부산 원도심인 서구 충무동·남부민동의 풍부한 자연자원과 다양한 역사·문화자원을 활용한 저탄소 녹색성장과 환경보호를 양립시켜 새로운 성장동력과 지역경제 활성화로 도시재생방안을 마련한다. 녹색기술을 활용한 경사지 주거재생, 도심형 항만재생, 원도심 상권재생의 3대 목표를 설정하고 6대 핵심 전략을 중심으로 지속가능한 녹색도시를 조성한다. 서구 저탄소 녹색도시 선도사업에서 노후화된 주거시설을 개선하기 위한 하우스 프로젝트을 통해 지역성에 맞는 주거모델을 제시하고 친환경 기술요소를 이용하여 자체에너지 생산, 그린 인프라를 이용하여 생태복원 및 바람길을 연결하여 미기후 조절을 가능하게 한다. 그리고 도심형 항만재생에서는 공동어시장에 발생하는 유기성폐기물을 바이오매스시스템 구축을 통하여 바이오에너지를 생산하며 해양친수공간 조성과 천마산을 연결하는 그린네트워크를 형성하여 부산의 대표적인 저탄소 녹색성장 명품도시로 조성한다. By suggesting the green city characterization measure for each region and zone that can lead the low carbon green city which is a new national vision in order to actively cope with the climate change, the global environment issue, we aim to seek for the measure to build up low carbon green city suitable for local characteristics. With low carbon green growth and environment protection by using abundant natural resources and various historical/cultural resources in Seo-gu Chungmu-dong and Nambumin-dong, the old downtown of Busan, the city reclamation measure can be prepared based on a new growth driving force and local economic vitalization. It is a general measure related to easing and adapting to climate change like water circulation, including setting up the three main goals like reclamation of residence on slopes, urban ports and business districts in old downtown based on green technology, and the six core strategies like establishing system of carbon reduction through using low carbon energy, improving the transportation structure through introducing green traffic system, having water/resource circulation system through low carbon circulation resource, having green construction system through applying green technology and environmentfriendly materials, building up ecotype greens based on the carbon absorption system through management of greens and urban forest and creating green community through private and public green partnership. It is possible to control microclimate by connecting wind ways, restoring ecology through using green infrastructure and producing its own energy based on environment-friendly technical elements as also suggesting residental models suitable for local characteristics based on the house project to improve obsolete residential facilities with low carbon green city leading project in Seo-gu. For the urban port reclamation, bio-energy is produced by building up biomass system through organic waste generated in the joint fish market. As also forming waterfront and green network connecting with Mt. Cheonma, it can be the representative low carbon green growth city in Busan.

조기유자망 어구의 개량 및 생력화 조업시스템 개발 : 3. 생력형 5단 양망기의 해상 성능 시험

김석종,구명성,강경범,서대범,정용진 제주대학교 해양과환경연구소 2005 해양과환경연구소 연구논문집 Vol.29 No.2

A rare case of extensive papillary muscle calcification in senile cardiac calcification syndrome

김은진;송봉근;강민호;손형래;홍수민;박동원;허승혜;김계연;최석구 인제대학교 2011 仁濟醫學 Vol.32 No.-

광범위 유두근 석회화는 흔하지 앉으며, 원인과 임상적 중요성에 관한 문헌만 드물게 찾아볼 수 있다. 반면에 작은 석회 침착은 노인에서 흔하며 심장 첨부에 주로 나타난다. 유두근 석회화는 관상동맥질환, 확장성 심근병증, 승모관 질환, 고칼슘혈증, 그리고 말기신부전에서 인산칼슘의 중가와 연관성이 있다. 저자는 심장초옴파와 MDCT를 통해 진단된 전외측 유두근의 광범위 석회화의 드문 사례가 있어 보고한다.

증점제를 사용한 고유동콘크리트의 기포조직과 내동해성에 관한 실험적 연구

김무한,권영진,강석표,여동구,김용로,장종호 충남대학교 산업기술연구소 2000 산업기술연구논문집 Vol.15 No.1

Recently, lots of studies for high flowing concrete have been suggested under practical use that it is only a way to solve the confronted problem. However, most studies have been concentrated on the manufacture method and properties of fresh concrete, but there is few studies for the durability of hardened concrete, specially for the freezing and thawing. It is generally known that the frost resistance of concrete is much affected by the air content in concrete and by the air void system. The frost resistance is also believed to vary with the strength of concrete. The purpose of this experimental study is to make a comparison between high flowing concrete using viscosity agent and ordinary concrete about the effect of the viscosity agent, air content and curing method on the frost resistance. As the result of tutus study, the frost resistance have not effect the viscosity agent but effect the different of curing methods.

고압 수증기 내에서 산화막 형성에 관한 연구

박경희,안순의,구경완,왕진석 충남대학교 산업기술연구소 2000 산업기술연구논문집 Vol.15 No.2

This paper shows experimentally that oxide layer on the p-type Si-substrate can grow at low temperature(500℃∼600℃) using high pressure water vapor system. As the result of experiment, oxide layer growth rate is about 0.19Å/min at 500℃, 0.43Å/min at 550℃, 1.2Å/min at 600℃ respectively. So, we know oxide layer growth follows reaction-controlled mechanism in given temperature range. Consequently, granting that oxide layer growth rate increases linearly to temperature over 600℃, we can expect oxide growth rate is 5.2Å/min at 1000℃. High pressure oxidation of silicon is particularly attractive for the thick oxidation of power MOSFET, because thermal oxide layers can grow at relatively low temperature in run times comparable to typical high-temperature. 1 atm conditions. In the condition of higher-temperature and high-pressure steam oxidation. the oxidation time is reduced significantly.

파노라마방사선사진 지수와 임플란트 실패와의 관계에 관한 연구

조현정,이원진,허민석,안창현,이진구,이삼선,최순철 大韓口腔顎顔面 放射線學會 2004 Imaging Science in Dentistry Vol.34 No.1

Purpose : Several panoramic indices have been suggested to assess bone quality from the morphology and width of mandibular cortex on panoramic radiography. The purpose of this study was to compare dental implant failure group with control group in panoramic mandibular index (PMI), mandibular cortical index (MCI), and gonion index (GI) and to determine the effect of these panoramic indices on dental implant failure. Materials and Methods : A case-control study was designed. Test group (n = 42) consisted of the patients who had their implants extracted because of peri-implantitis. Control group (n = 139) consisted of the patients who retained their implants over one year without any pathologic changes and had been followed up periodically. They had dental implants installed in their mandibles without bone augmentation surgery from 1991 to 2001. The following measures were collected for each patients: 1) PMI, MCI, and GI were measured twice at one-week interval on preoperative panoramic views; and 2) age, sex, implant length, implant type, installed location, occluding dentition state, and complication were investigated from the chart record. Results : The PMI showed moderate level of repeatability. The intra-observer agreement of MCI and GI were good. There was statistically significant difference in PMI between two groups. There were significant different patterns of distribution of MCI and GI between two groups. Among the panoramic indices, PMI and MCI showed significant correlation with dental implant failure. Conclusion : Panoramic indices can be used as reference data in estimating bone quality of edentulous patients who are to have implants installed in their mandibles.

신이식에서 이식신의 생존분석

오선미,김종학,황평주,구영선,강민규,나기량,김종섭,김성숙,이강욱,신영태,설종구,배진선,손기섭 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.2

To investigate the prognostic factors for the survival of transplanted kidney in patients with end-stage renal failure, 59 cases of renal transplantation from September 1986 to Feburary 1997 in Chungnam National University Hospital were analyzed retrospectively. The results were as follows: 1)The mean age of recipients was 33.8 years and that of doners was 38.9 years. The male to female ratio of recipients was 2.5:1, and that of donors was 1.03:1 2) Living related donore(LRD) were 79.6% and living non-related donors were 20.3%. The HLA-identical donors(ID) in LRD were 18.7% and HLA-haploidentical donors(HID) were 61.0%. In living non-related donors(LNRD), mean matched HLA-AB antigens were 1.56 and mean matched HLA-DR antigens were 0.56. 3) The average 5-year patient survival fate was 94%, and average 5-year graft survival rate was 70%. The 5-year graft survival fate of HLA-ID was 100%, and those HLA-HID and LNR were 70% and 36% respectively. 4) Total 33 episodes of acute rejection were found in 45.8% of transplanted patients. The number of acute rejection episode did not show significant difference between LRD and LNRD(P > 0.05). There was no significant difference in MLC between two groups(p > 0.05). 5) In comparison between the 18 patients who lost their graft function in 5 years and 17 patients who are maintaining graft function for more than 5 years, MLC was significantly lower in patients with functioning graft than of patients with non-functioning graft (p < 0.05). The number of rejection episode was also lower in patients with functioning graft than that of the patients with non-functioning graft(p < 0.05). However, there were no significant difference in recepient and donor age and history of pre-transplantation donor specific transfusion between two groups. With the results above, we can speculate that adequate donor selection according to good matched HLA typing and low MLC is very important for graft survival in renal transplantation. Prevention and treatment of acute rejection in renal transplantation is also na important factor for graft survival.

디지털 및 일반 측방두부규격방사선사진에서 측정 방법에 따른 계측치의 비교

김미자,허경회,이원진,허민석,이삼선,이진구,안병근,최순철 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.1

Purpose : To compare cephalometric measurement between measuring methods in digital and conventional lateral cephalometric radiograph. Materials and Methods : Twenty digital and conventional lateral cephalometric radiographs were selected. In digital group, cephalometric measurements were performed manually using hardcopies and automatically using VCeph^(TM) program on the monitor. In conventional group, the same measurements were performed manually on conventional films, and for automatic measurement conventional films were digitized by scanner. All measurements were performed twice by 4 observers, and 24 cephalometric variables were calculated and the time spent for each measurement was recorded. The differences in measurements data and the time spent for each measurement were compared within each group. Intra-observer and inter-observer comparisons were performed. Results : In both groups, no statistically significant difference between manual and automatic measurements was observed and most of the variables didn’t show statistically significant differences between methods. The observer with less experience tended to show statistically significant differences of measurements between methods, and differences from other observers. The differences of measurements between methods in digital group were lesser than those of conventional group with statistical significance in 8 variables out of 24. With automatic method and in digital group, the spent time was shorter. Conclusion : With direct digital radiograph, automatic method using manually idenitified landmarks can be preferable in cephalometric analysis.

흰쥐 생체시료 중 5-플루오로우라실 및 테가푸르의 안정성

장지현,박종국,강진형,정석재,심창구,구효정 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.3

5-Fluorouracil (5-FU) is an antimetabolite anticancer agent active against many types of solid tumors. Tegafur (TF), a prodrug of 5-FU, is frequently used in combination with uracil as dihydropyrimidine dehydrogenase (DPD) inhibitory fluoropyrimidine. We studied the stability of 5-FU and TF in biological fluids of rats and determined their bioavailability (BA) and excretion into bile, and urine. The drug concentrations were analyzed by an HPLC method. At room temperature, there was a 14-30% decrease in the concentration of 5-FU and TF in bile, urine, and plasma specimen at 10 and 100 μg/ml over 240 min. No significant difference was noted among the sample types or between two different concentrations of 10 and 100 μg/ml. The decrease in drug concentration was significantly less in samples kept on ice (6-12%) for both drugs. These data indicate that biological fluid samples containing 5-FU or TF in plasma, urine, or bile should be placed on ice during the sample collection. Following these storage guidelines, samples were collected after administration 50 ㎎/㎏ of each drug via i.v. or oral route. BA was 1.5 folds greater for TF (60%) than that of 5-FU (42%). Approximately 0.52 and 3.3% of the i.v. doses of 5-FU and TF was excreted into bile, respectively. Renal clearance of 5-FU was about 16% of its total body clearance. These results suggest that instability of 5-FU and TF in biological fluids should be considered in pharmacokinetic or pharmacogenomic studies.