활성탄에 의한 카페인 및 니코틴의 흡착특성

손진언,이성식,김달한,유명호,이만식 동아대학교 환경문제연구소 1994 硏究報告 Vol.17 No.1

Adsorption equilibrium and kinetics of Caffeine and Nicotine from aqueous solution on activated carbon were determined experimentally in a batch system. Then, the equilibrium data were expressed by the Freundlich type and the equilibrium constants were obtained. Diffusion coefficient were determined by comparing experimental decay curve with theoretical ones. Surface diffusion was consided to be dominant and the value of diffusion coefficient were depent of the amount adsorbed and the equilibrium concentration. Domestic activated carbon has nearly same amount of adsorption as imported activated carbon made by CALGON carbon Corp.

泡沫分離에 의한 亞鉛이온의 吸着特性

孫晋彦,李成植 동아대학교 환경문제연구소 1981 硏究報告 Vol.5 No.1

Foam Separations in batch operation were carried out in the system of ZnCl₂-Sodium lauryl sulfate in water. From the results, the technique of foam separations is applicable to purifying for surfactant Zinc Ion as found in wastewater treatment. The surface excess of Zinc Ion was a function of bulk concentration, itself and surfactant concentration, and Langmuir adsorqtion model, was fitted.

이원분산마크로장방형수지에 의한 파라니트로페놀의 흡착

손진언,김달한,후루야에이지,조영삼,이성식,야마시타세이치 東亞大學校 大學院 1991 大學院論文集 Vol.16 No.-

Uptake curves were obtained for p-nitrophenol/XAD-2000 resin system using a shallow-bed method for various concentration ranges at 298.2K. Distilled water was employed as solvent. The values of effective intraparticle diffusivity were detrermined by comparing experimental and theoretical uptake curves. The values obtained for solvent i. e, distilled water system was not dependent on the amount adsorbed in the higher concentration range. Those results shows that, except in the region where there is a low adsorbed amount, and adsorber packed with macrorecticular resin particles can be designed using a traditional pore diffusion model.

液膜에 의한 廢水중의 重金屬이온의 分離

孫晋彦,李成植,金鍾和,全成均 동아대학교 환경문제연구소 1986 硏究報告 Vol.9 No.1

The purpose of this paper was to separate the copper and nickel ions from waste water using supported liquid membrane The effect of a given amount of carrier and ammonia concentration of up-stream was described. We used the LIX65N as carriers. The results were as follows 1. The distribution ratio of copper ions at equilibrium was shown linear increment according o the mole ratio of carrier concentration versus the concentration of metal ions increased to 2.0. The maximum distribution ratio of copper ions exceeded that of nickel by approximately 4-fold when the liquid membrane was saturated by carrier 2. The important parameters governing flux were carrier and ammonia concentration. We compared these two parameters, and then the latter influenced more than the former to get higher flux. The copper ions reacted with ammonia in the up-stream, it formed a complexes of Cu(NH₃)₄^(2+), and then diffused to interface of liquid membrane. 3. The flux of metal ions were increased with enlarging the distribution ratio of ordinary extraction. The principle of coupled transport was carried out by the difference of concentration of hydrogen ions. 4. We can be selectively separated in the mixing soultion of copper and nickel ions using LIX65N as carrier.

內耳組織의 Na^+, K^+ ATPase 分布와 알부민輸送에 關한 超微形態學的 硏究

손진호,박경란,이영호,노승무,김원식 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

This study was carried out to investigate distribution of Na^+, K^+ -ATPase in the cochlear tissues by means of electron microscopic immunocytochemistry and transcytosis of albumin in the cochlear tissues. Ten cochleas obtained from guinea pigs were stained by avidin-biotin-peroxidase with anti-human Na^+, K^+ -ATPase rabbit IgG as primary antibody. Three guinea pigs were perfused with colloidal gold binding bovine serum albumin. Four were injected into the endolymphatic and perilymphatic spaces via oval and round windows. The cochlear tissues were observed with electron microscope. The results obtained were were as follows. Na^+, K^+ -ATPase was predominently distributed in basolateral infoldings and mitochondrial membranes and cristae, and moderately in the cytoplasmicn membrane and interdental cells. Albumin was distributed on the endothelial cells of the strial capillaries and surrounding interstitium. There were no albumins in marginal cells, intermediate cells, basal cells, Reissner' s membrane, and cells of the organ of Corti. According to the above results. it is suspected that transport of Na^+ and K^+ is performed in basolateral infoldings of marginal cells by active transport mechanism, and that immuncoytochemical method is more excellent to demonstrate Na^+, K^+ -ATPase than that of enzyme histochemistry. Transcytosis of albumin into the endolymphatics may be restricted by stria vascularis, Reissner' s membrane, and the cells of the organ of Corti.

활성탄탑에서-페놀-벤조산 이성분계의 흡착파과 특성

이영식,하기성,김달한,손진언 東亞大學校 大學院 1990 大學院論文集 Vol.15 No.-

From the experiments on the adsorption of binary mixtures of benzoic acid-phenol in the fixed bed column packed with activated carbon, the following results are obtained. 1. For the equilibrium adsorption of unicomponent and binary system are fairly well consistent with freundlich's equation. 2. The breakthrough time and selective separation are linearly increased with the lengh of adsorption column. And the slope of benzoic acid which has large equilibrium adsorption is larger than that of pherol. 3. The substitunt coefficients increase with the concentration ratio. 4. The increase in the flow rate does not bring the equivalent increase in the breakthrough time.

Glucagon 및 Cycloheximide 投與에 의한 흰쥐 肝細胞 lysosome의 變化에 관한 超微形態學的 硏究

이진식,김익동,배한익,서인수,김중길,곽정식,손태중 慶北大學校 醫科大學 1983 慶北醫大誌 Vol.24 No.2

저자는 체중 30∼35gm 정도의 ICR계 생쥐에 체중 100gm당 100㎍의 glucagon을 그리고 체중 100gm당 0.15mg의 cycloheximide를 각각 단독으로 또 이들을 같이 복강내에 병합 투여하여, 이때 간세포에 일어나는 형태학적 변화와 아울러 lysosome막의 유래의 일단을 알아보기 위한 실험성적을 요약하면 다음과 같다. 광학현미경적으로는 중심정맥 주위의 간세포이 종창과 한국성 지발변화가 나타났었는데, 그 정도는 glucagon 단독투여군과 cycloheximide와 glucagon을 병합투여한 군에서는 다같이 중등도로 일어났었다. 전자현미경적으로는 glucagon 단독투여 군에서는 간세포에 있어서의 lysosome의 현저한 증가, 특히 autophagic vacuole의 증가, 세포핵의 비대 및 핵소체수의 증가, 그리고 kupffer세포의 탐식 작용의 증가등이고 cycloheximide 단독투여군에서는 경한 lysosome의 증가, RER의 확장, 단열, ribosome의 탈락, free ribosome의 증가, Golgi complex의 위축, SER의 감소, mitochondria의 종창 및 공포화와 lipid droplet의 증가 등이다. 그리고 glucagon과 cycloheximide 병합투여군에서는 상기한 두가지 단독투여군의 소견과 여기에 더하여 peroxisome의 증가가 일어났으며, 이들 변화중 특히 autophagic vacuole의 증가는 glucagon 단독투여군보다 좀더 현저한 경향이었다. 이상의 연구성적으로 보아, glucagon은 간세포에 있어서 autophagy를 증가시킬 뿐 아니라, 핵에도 작용하여 그 비대를 일으키며, 이때 cycloheximide를 투여하여 단백합성을 억제하여도 autophagy를 저해하지는 않는다고 믿어진다. 따라서 autophagic vacuole의 한계막은 새롭게 신생된다기 보다는 세포내의 기존의 막, 예를 들면 SER, RER, Golgi막등 막성 성분에서 유래될 가능성이 지금으로서는 더 많은 것으로 생각된다. Glucagon은 autophagic vacuole을 증가시킬 뿐 아니라, cycloheximide를 투여한 후 glucagon을 투여한 경우에는 autophagic vacuole의 증가와 더불어 peroxisome도 증가시킬 것으로 추정된다. In order to investigate the morphologic changes and origin of membrane of lysosomes, the author administered glucagon, 100㎍ per 100gm of body weight, cycloheximide, 0.15㎎ per 100 gm of body weight and both to the healthy male ICR mice intraperitoncally. Each hepatic tissue was observed by light microscope and electron microscope. The results were summarized as follows. Light microscopically, swelling of heaptocytes and focal fatty change appeared around the-central vein. The severity of these changes was mild in the group administered glucagon and was moderate in groups administered cycloheximide alone, both cycloheximide and glucagon. Electron microscopically, in the group administered glucagon, marked increase of lysosomes, particularly autophagic vaculoles, enlargement of nuclei with increase of nuclcoli in thc hepatocytes and increase of phagocytosis in kupffer cells were appeared. In the group administered cycloheximide, slight increase of lysosomes, dilatation and fragmentation of RER, shedding of ribosomes, increase of free ribosomes, atrophy of Golgi complex, decrease of SER, swelling and vacuolizatlon of mitochondria, and increase of lipid droplets occured. In thr group aiministered both cycloheximide and glucagon, above findings in each group and additional increase of peroxisomes appeared. In these changes, increase of autophagic varuoles was more prominent in the group administered glucagon. From the above results, it is believed that glucagon induces enlargement of nuclei as increase of autophagy in the hepatocytes. At this time, in spite of suppression of protein synthesis by administration of cycloheximide, the autophage was not inhibited. Therefore it is more possible that the limiting membrane of autophagic vacuoles originates from preexisting membrane rather than front de novo synthesis. when glucagon was administered after administration of cycloheximide, peroxisomes as well as autophagic vacuoles were increased.

대한상하수도학회 국제저명인사 초청간담회

윤제용,손진식 대한상하수도학회 2002 상하수도학회지 Vol.16 No.6

活性炭에 의한 重金屬 시안化物 錯陰이온의 吸着特性

金柱奉,李成植,李來雨,孫晋彦 東亞大學校 1985 東亞論叢 Vol.22 No.1

It is the purpose of this study to investigate the possibility and mechanisms of complex formation for the removal of cyanide and toxic heavy metals from mining and electroplating industrial wastewater simultaneously. The adsorption forms of heavy metals from a synthesized wastecyanide water by activated carbon is discussed. Under the cyanide complexiation, mercury ion is adsorbed in the formation of complex anion as ?? and Hg(CN)₃, but zinc and cadmium are also as ?? and ?/?. The effects are established under the presence of ?? in the concentration range ?? mol/ℓto ?? mol/ℓand the presence of heavy metals.

Change of Molecular Weight of Organic Matters through Unit Water Treatment Process and Associated Chlorination Byproducts Formation

Jin Sik Sohn,Hyo Soon Kang,Ji Hee Han,Yeo Min Yoon 대한환경공학회 2007 Environmental Engineering Research Vol.12 No.5

The objectives of this study were to evaluate the change of molecular weight (MW) profiles in natural organic matter (NOM) through various treatment processes (coagulation, granular activated carbon (GAC), and ozonation) using high performance size exclusion chromatography based on ultraviolet absorbance and dissolved organic detection (HPSEC-UVA-DOC). In addition, relationships between MW profiles and disinfection by-production (DBP) formation were evaluated. Each treatment process results in significant different effects on NOM profiles. Coagulation is effective to remove high molecular weight NOM, while GAC is effective to remove low molecular weight NOM. Ozonation removes only a small portion of NOM, while it induces a significant reduction of UV absorbance due to breakdown of the aromatic groups. All treated waters are chlorinated, and chlorination DBPs such as trihalomethanes (THMs) and haloacetic acids (HAAs) are measured under formation potential conditions. Both THM and HAA formation potentials were significantly reduced through the coagulation process. GAC was more effective to reduce THM formation compared to HAA formation reduction, while ozonation showed significant HAA reduction compared to THM reduction.