결핵성 부고환염의 자기공명 영상 소견

장지연,김동훈 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

Tuberculous epididymitis occours sporadically and represents a specific secondary subacute or chronic inflammatory process involving the epididymis. And the tuberculous epididymitis should be differentiated with nontuberculous one, because delaying administration of specific antituberculous chemotherapy can result in the progression of the disease. The authors report on a 21 years old man with tuberculous epididymitis combined with active pulmonary tuberculosis who presented with scrotal swelling.

Urban Mapping Game

지장훈 경기대학교 건축전문대학원 2007 경기대학교 건축대학원 논문집 Vol.11 No.-

Various propositions have been made to connect the axes, which were broken by the unsystematic city planning and developing without thought for the environment, of the urban since late of 1999. As increasing interests of the urbiculture and trying to get a realistic competitive power by each cities after operating the local self-government system, Mapping has been developed. Mapping of the architecture reflects all the data regarding urban design. It's a method to solve an actual problem architecturally and more positive way to reflect data though the Mapping to solve the problem rationally than intuitive Design of the architect. It is a problem to exist in architecture to take conditions of the Mapping progress maximally. The Mapping progress substantiates a program, culture and society environmental component, Physical component (density-infrastructure component), and natural component, etc. Moreover, it substantiates immaterial to material component. The architecture is influenced by a social environment at the time of construction. Modern architecture that should deal with fast changes of the modern society leads the Mapping progress to take a variety of actions in the mixed space. The city is composed of the Invisible Flow which changes continuously and Field-Force. It is necessary to have a new angle to loot at city. The city can be thought the flow from a dense of buildings and Field Force. Many phenomena that arise in city are not able to explain with an influence among buildings but are able to explain with a collision and combination of city-flows. The study is a Design game for establishing the rule, which is based on Game theory, of Design Process and presenting an architectural methodology with analysis of city organization by Mapping to solve problems as stated above, through the process to connect cultural axes from the Jangchung-dong though Ssangrim-dong and Ehwa-dong to Heahwa-dong(3.1Km). As condensed Field Force of the city appears viably, various conditions are happened through an Interference and Collision of the city organizations by diverse Parameters. As trying the various phenomena to the Urban Mapping game, the study is to present new possibilities of reorganization of the city space, to confirm a cultural identification in the city, and to reveal a character as a local place which was hidden by strong power. 1999년 후반부터 체계적이지 못한 도시계획과 난 개발로 인해 끊어진 도심의 축(Axis)들을 다시 연결하고자 여러 가지 제안들을 내 놓고 있으며, 지방자치제 실시 이후 도시경영에 대한 관심도가 높아지면서, 현실적으로 도시들은 도시경쟁력을 갖추려는 도시마케팅 차원의 노력을 시도하고 있음에 착안하였다. 건축에서의 Mapping은 설계(Design)에 도시가 가지고 있는 모든 Data들을 반영하려고 노력한다. Mapping을 통해 현실의 문제를 건축적으로 해결하는 방법을 모색하며, 건축이 직면한 문제를 합리적으로 해결하기 위해서는 건축가의 직관에 의한 Design보다는 Mapping을 통해 얻어낸 Data를 보다 적극적으로 반영하여 형태를 만들어 보고자 하는 것이다. Mapping과정에서 얻어지는 조건들을 최대한 수용하는 건축을 하는 것은 그것이 건축에 존재하는 현실적인 문제이기도 하다. 이러한 Mapping Process는 프로그램, 인문·사회 환경적 요소, 물리적 요소 (밀도·Infrastructure의 요소), 자연적요소 등을 건축적으로 실체화 시키는 것이며, 비물질적인 것을 물질화 시키는 것이다. 또한, 건축은 건축될 당시의 사회적 영향을 지대하게 받는다. 현대 사회의 빠른 변화에 대응하며, 그 변화를 수용해야만 하는 현대의 건축은 공간의 혼성화와 혼성화된 공간에서 다양한 행위들을 수용할 수 있도록 하는 Mapping 과정을 유도한다. 도시는 계속해서 변화하는 보이지 않는 흐름(Invisible Flow)과 힘의 장(Field-force)으로 구성된다. 도시를 바라보는 관점의 변화가 필요하다. 도시 자체를 건물들로 이루어진 집합체로부터 흐름과 힘의 파장(Field Force)으로 도시를 바라본다. 도시에서 일어나는 수많은 현상들은 건물간의 영향만으로 설명할 수 없고 도시의 흐름들이 서로 충돌하고 결합됨으로서 발생된다고 설명할 수 있다. 본 연구는 과거 장충동을 시작으로 쌍림동, 이화동을 거쳐 동숭동의 혜화동 로터리까지에 이르는 3.1Km의 문화적 축의 연결하고자 하는 작업을 통해, 서두에 언급한 여러 가지 문제점을 게임이론(Game Theory)을 바탕으로 Design Process의 Rule을 설정하고 Mapping을 통해 도시조직을 분석하여 건축적 방법론을 제시하는 Design Game이다. 도시가 응축하고 있는 힘의 장(Field Force)을 가시적으로 드러내고, 다양한 Parameter에 의해 도시조직들이 서로 간섭(Interference)되고 충돌(Collision)함에 따라 다양한 조건들이 발생하게 된다. 이러한 다양한 현상을 Urban Mapping Game을 해봄으로서 보이지 않는 강한 힘에 가려있던 지역적 장소성을 다시 드러내고, 도시 내에서 문화적 정체성을 확인시켜주며 또한, 도시 공간을 재구성함에 있어 새로운 가능성들을 제시하고자 하는데 있다.

라미부딘 내성 만성 B형 간염 환자에서의 아데포비어의 치료 효과

이지숙,장리라,이상욱,한병훈,윤병철 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

Backgrounds/Aims : Adefovir dipivoxil(ADV) has been shown to be effective against lamivudine resistant strain of hepatitis B virus. But continuation of lamivudine therapy or switching to Adefovir dipivoxil in patients with viral breakthrough after long term lamivudine therapy are controversial. To find efficacy of adefovir dipivoxil, we retrospectively assessed clinical course after lamivudine resistance in patients who changed adefovir dipivoxil and continued lamivudine therapy. Methods : 58 patients with lamivudine resistant HBV mutants after at least 6 months of lamivudine treatment were included in this study. 24 of the 58 patients were treated with ADV and rest of them were continued the lamivudine therapy after lamivudine resistance. The continuous lamivudine treatment group (n=34) was divided into two groups according to ALT count (ALT≧40, n=19 vs ALT<40, n=16) The clinical course and the biochemical and virological response of the switching adefovir group were compared with those of continuing lamivudine group. HBV genotypes and YMDD mutation site was anaylzed by TRUGENE HBV Genotyping. Results : At twelve months, the levels of median serum HBV DNA and ALT was decreased and albumin was improved significantly(P<0.01) in adefovir switching group compared with lamivudine sustained group, especially ALT was elevated more than 40. There is no significant differences between adefovir switching group and lamivudine sustained group (ALT<40, n=15). This study showed that adefovir dipivoxil reduces HBV replication and improves not only biochemical markers of disease activity, but also liver function. HBV genotypes of 58 patients were all C and rtM204I/V mutant was the most common. Conclusion : This study provides an evidence that adefovir dipivoxil can be effective in the treatment of lamivudine-resistant HBV mutants, especially ALT elevated.

선택적 NCMA 방법을 이용한 분할 블라인드 적응 등화기의 성능 분석

홍지훈,장태정 江原大學校 産業技術硏究所 2001 産業技術硏究 Vol.21 No.B

In this paper, the selective normalized constant modulus algorithm(SNCMA) is applied to a fractionally spaced equalizer. The fractionally spaced equalizer is insensitive to the sampling timing because it processes received signals with the sampling rate larger than the symbol rate. The SNCMA improves the convergence rate by using the large step size for the most outer covering symbol belonging to the trust-level. This blind equalizer exhibits a fast start-up convergence rate as well as a reduced steady-state residual error compared to the fractionally spaced blind equalizer and the T-spaced blind equalizer using conventional blind algorithms.

소방대원들의 실내, 실외 근무 형태에 따른 유산소 운동능력 및 등속성 근력

김남익,장지훈,성기홍,윤성 한국유산소운동과학회 2002 대한스포츠융합학회지 (jcses) Vol.6 No.1

The purpose of study was to investigate the influence of cardiopulmonary function and isokinetic knee joint muscle strength on duty form in the fm fighters. 28men who aged 30-40 years were measured by resting pulmonary function test, exercise stress test(Q4500, Quinton, Co.) and isokinetic knee joint muscle strength testing(Cybex 6000 dynamometer system). Subjects were divided into the 2 groups that were indoor duty group and outdoor duty group. Statistical analysis was performed using analysis of variance t-test. Major findings and conclusion are as follows: In body fat test, outdoor duty groups was showed lower than that of indoor duty group. For the lung function test at rest, lung volume, vital capacity, MVV, FEVO.5-1.0, expiratory and inspiratory flow rate were checked. In results, outdoor duty group was showed higher than that of indoor duty group. During exercise stress test, heart rate, ventilation, and oxygen uptake, were checked by automatic gas analyzer. In results, outdoor duty group was showed higher than that of indoor duty group. In isokmetic knee joint muscle strength, peak torque and average power of indoor duty group was showed significantly lower than that of outdoor duty group. At Comparison of right and left knee joint, isokinetic strength, isokinetic power and isokimtic endurance of right knee joint was showed significantly higher then that of left knee joint, but in 60 degree per second, left knee joint was showed higher then that of right knee joint. Result from this investigation show greater personal training and fire quell a not, emergency rescue activity was increased knee joint muscle strength. Therefore, physical fitness and health maintenance programs for fire fighters have been developed, implemented and proven to reduce morbidity and mortality and financial expenditures.

UV 센서를 위한 Spiroxazine LB 단분자막 특성에 대한 연구

최성욱,박은진,장지훈,김재호,강신원 경북대학교 센서기술연구소 2002 센서技術學術大會論文集 Vol.13 No.1

석면관련 폐질환의 진단에 있어서 흉부고해상도전산화단층촬영검사(HRCT)의 유용성

이현재,손지언,,홍영습,,이영일,예병진,유창훈,정갑열,김상훈,임형준,장은철,김정만,김준연 大韓産業醫學會 2006 대한직업환경의학회지 Vol.18 No.2

목적: 석면에 노출된 근로자에서 석면관련 폐질환의 양상을 분석하고 진단에 있어 HRCT의 유용성을 연구하여 석면에 대한 의학적 감시프로그램의 개발에 기여하고자 하였다. 방법: 석면에 직접 노출되는 작업자 68명과 간접 노출되는 작업자 94명 등 총 162명에 대해 OSHA 석면 표준, 의학적 감시 프로그램에 따라 단순 흉부방사선검사, 폐활량검사 및 우리나라 실정에 맞게 일부 수정한 의학적 설문지를 통해 면접조사의 방식으로 환자에 관한 정보를 수집하였으며, 자료의 신뢰성을 확보하기 위하여 면접조사는 1달 이상의 기간을 두고 2차례에 걸쳐 실시된 후 확인, 수정하였다. 또한, 석면관련 폐질환을 확진하기 위하여 HRCT를 추가적으로 실시하였다. 결과: HRCT결과 석면관련 폐질환의 유병율은 162명의 근로자중 17명으로 10.5%였는데, 직접 노출군에서 10명 (14.7%), 간접 노출군에서 7명 (7.4%)이었다. HRCT와 비교할 때 단순 흉부방사선검사의 민감도와 특이도는 각각 70.6%와 98.6%이었고, 양성 예측도와 음성 예측도는 각각 85.7%와 96.6%으로, HRCT는 단순흉부방사선검사에 비해 민감도가 높아 초기 석면관련 폐질환을 진단하는데 효과적이었다. 석면관련 폐질환의 진단에 있어 HRCT와 폐활량검사 사이에 유의한 관련성이 관찰되었다. HRCT 결과 석면관련 폐질환의 유무와 의학적 설문조사 결과의 빈도분석을 실시한 결과, 유의한 변수는 작업기간, 흡연량, 호흡기질환의 과거력, 기침, 호흡곤란이었다. 결론: HRCT는 석면관련 폐질환의 진단에 있어 단순 흉부방사선검사와 비교하여 민감도가 높아 초기 진단에 유용하므로 단순 흉부방사선선검사 결과 석면관련 폐질환소견을 보일 때뿐만 아니라, 정상소견을 보이더라도 폐활량 검사결과와 근무력, 흡연력, 호흡기질환의 과거력, 기침, 호흡곤란 등의 호흡기 증상을 참고하여 HRCT검사를 고려해야 한다. 또한, 본 연구에서 관련성이 없었던 요인들에 대해서도 향후 연관성을 규명하는 광범위한 전향적 연구가 필요하다. Objectives: This study was carried out to improve the medical surveillance program of workers exposed to asbestos by examining the usefulness of High Resolution Computed Tomography (HRCT) in the diagnosis of asbestos-related lung disease. Methods: The study subjects comprised 162 workers in a ship-repairing yard, 68 of whom had been directly exposed to asbestos and 94 indirectly exposed. The 'Occupational Safety & Health Administration (OSHA) asbestos standard, medical surveilance program' and HRCT were conducted to analyze the aspects of the asbestos-related lung disease. The OSHA asbestos standard, medical surveilance program consists of simple chest x-ray, spirometry and medical questionnarie. Results: Seventeen (10.5%) of the 162 subjects, 10 (14.7%) directly exposed and 7 (7.4%) indirectly exposed, revealed asbestos-related lung disease on HRCT. The sensitivity and specificity of simple chest x-ray for asbestos-related lung disease were 70.6% and 98.6%, and the positive and negative predictive values were 85.7% and 96.6% respectively, as compared with HRCT, HRCT was an effective diagnostic tool especially to detect early asbestos-related lung disease. The study results indicated a relative significant association between the results of spirometry and HRCT. The variables significantly associated with asbestos-related lung disease on HRCT were work duration, smoking history (pack-years), past history of respiratory disease, cough and dyspnea. Conclusions: In the diagnosis of asbestos-related lung disease, HRCT should be considered not only for workers with positive findings on simple chest x-ray, but also workers with specific findings on spirometry, occupational history, smoking history, and past history of respiratory disease, or with respiratory symptoms such as cough and dyspnea.

여수국가산업단지 인근 지역 대기오염물질 농도에 영향을 미치는 요인분석

김민영,변정훈,이영훈,이건영,한지은,이예림,임지현,장봉기 순천향대학교 기초과학연구소 2022 순천향자연과학연구 논문집 Vol.28 No.1,2

Eight monitoring stations in the Yeosu National Industrial Complex will determine the concentration of air pollutants measured every hour in 2019, analyze what factors affect them, and how they correlate with the air pollutant measurements. Six air pollutants (SO2, NO2, O3, CO, PM-10 and PM-2.5) measured at eight monitoring stations around Yeosu National Industrial Complex (Seogang-dong, Wolnae-dong, Munsu-dong, Yeocheon-dong, Deokchung-dong, Hwayang-myeon, Yulchon-myeon, Samil-dong) the measurement data for each hour of the year were downloaded to analyze the concentration by weather condition, time zone, season, separation distance from Yeosu Industrial Complex, and separation distance from Gwangyang Industrial Complex. SO2, NO2, and CO concentrations were significantly higher in winter, significantly lower in summer, and O3, PM-10, and PM-2.5 concentrations were significantly higher in spring. SO2, CO, PM-10, and PM-2.5 concentrations were significantly higher between 10 a.m. and 12 p.m., NO2 concentrations were significantly higher between 7 a.m. and 9 a.m., and O3 concentrations were significantly higher between 13 p.m. and 15 p.m.(p<0.001). The concentration of air pollutants (SO2, NO2, CO, PM-10, PM-2.5) excluding O3 was found to have a negative (-) correlation with weather condition, and in the case of O3, it was found to have a positive (+) correlation with PM-10, PM-2.5, temperature and wind speed. It was confirmed that the concentration of air pollutants emitted from the Yeosu National Industrial Complex differs depending on the season, time and distance to the industrial complex. This study aims to establish measures to minimize health damage to residents living relatively close to the industrial complex and contribute to the establishment of management and response measures according to the properties of substances to reduce the concentration of air pollutants in the future.

두개강내로 전이된 Adenoid Cystic Carcinoma 2례 : 증례보고 Report of Two Cases

송재욱,윤상민,이창훈,장지수,이승훈,조경자,강신광 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.10

The authors describe two cases of unusual intracranial metastatic adenoid cystic carcinomas. A 42-year-old woman had a right pariental epidural metastatic mass. presumed hematogenous. spread from a primary tumor in the parotid gland. In second case, a 32-year-old man had a intracranial metastatic adenoid cystic carcinoma mimicking calcified psammomatous meningioma on CT scans. We present these unusual cases with a review of relevant literature and a discussion of possible pathogenesis.

원발성 척추 악성 신경초종 : 증례보고 3례 Case Report

김진국,송재욱,박우민,장지수,이창훈,이승훈 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.5