http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
수술로 호전되지 않은 췌장 농양을 내시경 치료로 완치한 1 예
서희영;전태주;김선영;강미선;허란;박지영;서동대;오태훈 인제대학교 백병원 2011 仁濟醫學 Vol.32 No.-
Necrotizing pancreatitis develops in about 10-20% of patients with acute pancreatitis, and pancreatic abscesses develop in 3% of them. The mortality of pancreatic abscess has been reported up to 40% in one study. Recently, there are several reports that show good results with n on-surgical therapy, such as percutaneous drainage and endoscopic drainage, but if the non-surgical drainage fails, surgical therapy are recommended. However, there is no definite therapeutic method which is suggested yet so far after the failure of the surgical drainage. So we report the case in which we experienced successful treatment of pancreatic abscess by endoscopic removal of necrotic tissue through the gastrocystostomy, after the failure of the surgical debridement and internal drainage through gastrocystostomy.
소원섭,이지연,강희라,손원진,허승덕 대구대학교 특수교육재활과학연구소 2012 再活科學硏究 Vol.30 No.1
이 연구는 이학적·청각학적 정상 소견을 가진 성인들의 다중주파수 고막운동도(multi-frequency tympanogram, MFT)와 다중성분 고막운동도(multi-component tympanogram, MCT)의 특성을 알아보고자 하였다. 연구 참여자는 D대학교 재학 중인 19명(M:F=9:10, 만 19∼23세)으로 하였다. MCT는 각 성분(admittance; Y, susceptance; B, conductance; G)별 정점의 수를 확인하였고, MFT는 200 ㎐부터 2 ㎑ 순음에 대한 고막 긴장 및 이완상태에서 전도율을 통해 공명주파수와 ΔB, Δ∅를 각각 구하였다. MCT는 668 ㎐ 자극에 대해 47.4 %가 1Y1B1G를, 52.6 %가1Y3B1G를 보였고, MFT의 공명주파수는 829~1,213(1,021±192) ㎐, ΔB와 Δ∅의 평균은 각각 –0.18, -19.3으로 관 찰되었다. This study will be to confirm the characteristic of Multi-component tympanogram(MCT) and Multi-frequency tympanogram(MFT) of adults who have physical and audiological normal findings. Participants were 19 students(M:F = 9:10) who are attending D-university. MCT checked the number of peaks per each component(admittance; Y, susceptance; B, conductance; G) and MFT got the resonance frequency through the conductivity rate of tympanic membrane's tense and relaxation state, and ΔB, Δ∅ respectively. 47.4% of MCT showed 1Y1B1G about 668 ㎐ stimulus and 52.6% of that showed 1Y3B1G. Resonance frequency of MFT was 829~1,213(1,021±192) ㎐, and the average of ΔB and Δ∅ was observed -0.18, -19.3 respectively.
강미선;박상훈;박지영 서희영;허란;김상현 인제대학교 백병원 2011 仁濟醫學 Vol.32 No.-
Acute fatty liver of pregnancy (AFLP) was first described as a specific clinical entity in 1940 and thought to be universally fatal. Maternal mortality in the past approached 75 percent. However early diagnosis and prompt delivery have dramatically improved the prognosis, and maternal mortality rate is now less than 18 percent. A early diagnosis, a prompt delivery, and a intensive supportive care have improved maternal and perinatal outcome. We report a 30—year—old woman at 37 weeks gestation who have multiple complications including acute pancreatitis in AFLP. She was complicated with acute renal failure, disseminated intravascular coagulation, duodenal ulcer bleeding, spontaneous bacterial peritonitis, pulmonary edema and acute pancreatitis.
소학교령기(1895-1905) 관·공립소학교교육의 성격에 대한 고찰
이성은,김정효,정희숙,이해지,허선영 한국초등교육학회 2004 초등교육연구 Vol.17 No.1
본 연구의 목적은 국가 주도의 기초 공교육의 효시가 된 소학교령기(1895-1905) 관, 공립소학교교육의 성격을 탐구함으로써, 우리나라 초등교육기원에서 보여지는 특성을 재조명하려는 데에 있다. 이를 위해 소학교령기의 사회적 상황과 교육적 요구, 초등학교의 교육목적, 교육내용 및 방법, 학습자계층과 교원양성과 처우에 대해 알아봄으로써, 당시 초등학교교육의 성격이 어떠했는지 규명하였다. 연구결과, 이 당시 관, 공립소학교는 사회 통합적이라기보다는 구국적 국민계몽교육의 성격을 띠었으며, 보편적 아동교육 이라기보다는 혁신적 근대교육을 상징하였고, 현실안주적 보통교육 이라기보다는 미래지향적 교육의 성격을 띠었다. 결론적으로 다양한 시대상황적 한계에도 불구하고 교육개혁의 의지는 대단하였던 것으로 평가되어졌다. The purpose of this study was to search for the nature of public primary school education in beginning period Enlightenment in Korea(1895-1905) in terms of the aims, the educational contents and methods, and the learner and teacher. For the purpose, the contemporary governmental documents, the newspapers, and other historic materials were collected and analyzed and the school sites were visited. The nature of public primary school education in beginning period of Enlightenment, was revealed as follows: First, it was not for the social consensus, but for the enlightenment of the people against nationalism. Second, it was not universal child education, but innovational elite education, Third, it did reflect not the present need, but the future need. In conclusion, it can be said that their intention of establishment of modem primary school has been underestimated and that their effort for educational reform should be reevaluated. But the research result suggests that public primary school education needs the balance not only between national needs and individual needs, but also between present needs and the future need.
A case of capecitabine-induced discoid lupus erythematosus
( Ji Hye Heo ),( Han Na Hyun ),( Seon Bok Lee ),( Hee Seong Yoon ),( Si Hyub Lee ),( Seung Dohn Yeom ),( Jeonghyun Shin ),( Gwang Seong Choi ),( Ji Won Byun ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1
There are a few reports of capecitabine-induced cutaneous lupus erythematosus (CLE), of which most of are subacute CLE. In particular, only one case showed discoid lupus erythematosus (DLE)-like features. Capecitabine is an oral fluoropyrimidine carbamate designed to generate 5-fluorouracil preferentially in tumor tissue through exploitation of higher intratumoral concentrations of thymidine phosphorylase and has less systemic toxicity than 5-fluorouracil administered through intravenous processes. The occurrence of druginduced CLE is related to the use of the drug in a timely manner, followed by the improvement of skin symptoms after discontinuation of the offending drug within several weeks. Stopping implicated medication is the initial management of drug-induced CLE. We report an interesting case of oral capecitabine-induced DLE with discoid and malar rashes, which had not occurred using LF protocol (leucovorin plus 5-fluorouracil) previously, that could not be provoked after changing chemotherapy from a capecitabine (a pro-drug of 5-fluorouracil) to FOLFIRI regimen containing leucovorin, 5-fluorouracil, and irinotecan. This case is meaningful for considering the unknown metabolic components acting on converting capecitabine to 5-fluorouracil of CLE induced by oral capecitabine.
A case of spindle cell hemangioma
( Ji Hye Heo ),( Seon Bok Lee ),( Hee Seong Yoon ),( Si Hyub Lee ),( Seung Dohn Yeom ),( Jeonghyun Shin ),( Gwang Seong Choi ),( Ji Won Byun ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1
Spindle cell hamangioma is an uncommon benign vascular tumor. It usually presents as dermal or subcutaneous nodule and most commonly arises in distal extremities. The histopathologic findings are coexistence of dilated and congested cavernous space and more solid area composed of spindle-shaped cells consisting epithelioid type in part. Immunohistochemical findings show variable positivity with endothelial markers depending on the composition of vascular endothelial cells and epithelioid cells in solid area. Surgical excision is treatment of choice and follow-up is necessary because of the possibility of recurrence. We report a case of a 56-year-old woman presented with tender bluish to skin colored mass on the left sole for several months ago. Ultrasound of the lesion revealed an well defined hypoechoic mass at subcutaneous layer with no vascularity. Surgical removal was performed. Histopathologic findings showed dermal tumor composing of spindle cells with cytologic atypia but no mitosis and dilated and thin-walled vascular spaces. There were hemosiderin deposition and collagen dissection. As differential diagnoses, spindle cell hemangioma, Kaposi sarcoma, angiosarcoma, hobnail hemangioma and hemangioendothelioma can be considered. Immunohistochemical stains for CD31, ERG and SMA were positive but CD34 and HHV-8 were negative. Ki-67 was presented approximately 1% positivity. A final diagnosis of spindle cell hemangioma was made.
[P345] A case of pseudovascular squamous cell carcinoma
( Ji Hye Heo ),( Hee Seong Yoon ),( Si Hyub Lee ),( Seung Dohn Yeom ),( Ji Won Byun ),( Gwang Seong Choi ),( Jeonghyun Shin ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1
Pseudovascular squamous cell carcinoma (SCC) is one of the rare variant of acantholytic SCC. It usually arises in sun-exposed sites such as head and neck in middle-aged or elderly patients. The histologic findings are pseudovascular channels lined with neoplastic cells and acantholytic cells moving from squamous nest. Immunohistochemical findings are positivity with monoclonal antibodies to cytokeratin and vimentin and negativity in vascular markers. Mohs micrographic surgery or surgical excision which is available to access the tumor margin is the primary management of high-risk cutaneous SCC. Radiation therapy is also used in cases suspected incomplete surgical removal. We report a case of a 67-year-old man presented with pruritic and painful erythematous grouped papules on the right chin area for two months ago and also in the right oral mucosa where the lesion had started first. Skin biopsy findings showed overlying epidermis permeating down with irregular shaped cellular proliferation, neoplastic cells with pleomorphic nuclei and acantholytic cells in cleft of dilated vessels. Stains for high-molecular weight cytokeratin and p63 were all positive in tumor cells and Ki-67 was presented approximately 10% positivity. It was consistent with pseudovascular SCC. We could not monitor the patient because of failure to follow up. To our best knowledge, this is the first case report on pseudovascular SCC in Korean dermatologic literature.
Genetic mutations and clinicopathological correlation in Korean melanoma - preliminary study
( Ji Hye Heo ),( Seon Bok Lee ),( Hee Seong Yoon ),( Si Hyub Lee ),( Jeonghyun Shin ),( Gwang Seong Choi ),( Ji Won Byun ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.2
Background: Recently, identifying individual mutated genes in cutaneous melanoma have emerged as effective biomarkers and therapeutic targets. Next-generation sequencing (NGS) shows comprehensive genomic mutations with high sensitivity. Objectives: We assessed the genetic alteration in patients with melanoma and their prognosis. Methods: We analyzed clinicopathological features of 11 patients with melanoma who obtained surgical resection and examined genetic mutations using NGS. Results: Among 11 cases of melanoma, gene mutations were identified in five. Case #1 presented lentigo maligna melanoma with vertical growth pattern on the neck. NGS identified CCND1 amplification and TP53 mutation. No recurrence was observed for 21 months without adjuvant treatment. Case #2 showed acral lentiginous melanoma (ALM) on the foot. NRAS mutation was identified, and metastasis to lymph nodes and lung occurred 8 months after surgery. After eighteenth anti-PD1 therapy, the treatment was changed to dacarbazine due to disease progression. Case #3 presented ALM on the great toe and case #4 presented nodular melanoma on the heel. NGS confirmed RAF1 amplification and KRAS mutation, and FGFR1 amplification and PTEN deletion, respectively. In case #5, tumorigenic phase of ALM developed on the sole and KIT gain was found. There is no recurrence after surgery in case #3 and #5. Conclusion: Further studies are needed to analyze the factors affecting therapeutic outcome including genetic mutations and target therapy.