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RISS 인기검색어
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- 저자 : ( Jeongha Wie ) (검색결과 2 건)
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The Influence of previous vaginal delivery on cervical length
( Seonghye Park ),( Ji Hea Byun ),( Jeongha Wie ),( In Yang Park ),( Ji Young Kwon ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-
Objective: Cervical length (CL) is a potential screening tool to predict preterm delivery for high risk women. Also it can be used for prediction of spontaneous labor or successful induction of labor. The objection of this presentation was to assess association between CL and previous vaginal delivery. Methods: Prospective observational cohort study was conducted from Jul. 2015 to Dec. 2017 at tertiary hospital. We measured CL at 18- 22 weeks, 22-26 weeks, 30-32 weeks and 36-37 weeks for all pregnant women who visited our hospital for antenatal care. Pregnant women with multifetal pregnancy, cerclage during pregnancy, fetal death in uterus and preterm delivery were excluded. Student t test was conducted between history of previous delivery and cervical length at each gestational week. Results: We included 595 pregnant women and their records of CL. At 18-22 weeks of gestation, there was no significant association between previous vaginal delivery and CL. At 22-26 weeks of gestation, women with previous vaginal delivery (N = 356) had a shorter CL compared with women without previous vaginal delivery (N=239). (mean CL in women with previous vaginal delivery 34.8 ± 5.8 mm, women without previous vaginal delivery, 36.4 ± 6.3 mm, P = 0.033). At 30-32 and 36-37 weeks of gestation, women with previous vaginal delivery had shorter CL than women without history of vaginal delivery significantly (P= 0.038 and 0.002, respectively). Maternal height, body mass index, birthweight, and gestational week at delivery were not associated with history of vaginal delivery. Conclusion: CL at 22-26 weeks and at 30 -32 weeks and 36-37 weeks are significantly associated with previous vaginal delivery. When we measure and use CL as a predictor for preterm or term labor, history of vaginal delivery should considered.
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Association between Ultrasonography Findings and Abnormal Karyotypes in Early Pregnancy Loss
( Jaeyoung Pae ),( Jaeyoung Park ),( Sinyoung Kim ),( Rayon Kim ),( Jeongha Wie ),( Hyun Sun Ko ),( In Yang Park ),( Jong Chul Shin ) 대한주산의학회 2020 Perinatology Vol.31 No.2
Objective: Chromosomal abnormality in the fetus is a major cause of early pregnancy loss (EPL). It is considered that maternal age is a risk factor of chromosomal abnormality in the fetus. The objective of this study was to evaluate the association between ultrasonography findings and abnormal karyotypes in EPL. Methods: This retrospective analysis assessed 217 cases of EPL occurring between 2009 and 2018, which have the results of cytogenetic analysis following miscarriage, as well as the ultrasonography finding. The correlations between the ultrasonography findings and the karyotypes were evaluated. Results: Of the 217 cases, after excluding cases with no mitotic cells, karyotypes analysis was performed in 190 cases. The overall rate of abnormal karyotypes was 32.1% (61/190). Mean maternal age was significantly higher in the abnormal karyotype group (35.66±4.22 vs. 33.79±4.02 years, respectively, P=0.006). The embryo/gestational sac ratios was significantly smaller in the abnormal karyotype group (0.3±0.18 vs. 0.43±0.3, P=0.022). In the multivariate logistic regression analysis, smaller embryo/gestational sac ratios (≤0.4) was a significant risk factor of abnormal karyotype (adjusted odds ratio [OR] 2.43, 95% confidence interval [CI]: 1.086-5.437, P=0.031), after the adjustment with the number of previous abortion. The chromosomal abnormality rate was significantly higher in male miscarriage (adjusted OR 2.36, 95% CI: 1.003-5.443, P=0.049). Conclusion: By identifying a predictive factor of chromosomal abnormalities in embryonic abortion, this study presented ultrasonography findings to consider cytogenetic analysis and an easy-to-use cut off value, small embryo/gestational sac ratio (≤0.4) at a patient’s request of chromosomal study in the fetus.
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