해상형 국립공원 탐방수요의 요인분해

모수원 ( Mo Soo-won ),이광배 ( Lee Kwang-bae ),박정환 ( Park Jeong-hwan ) 한국도서(섬)학회 2018 韓國島嶼硏究 Vol.30 No.2

국내관광은 국제관광의 변동성이 주는 충격을 완화하려 관광산업의 안정성을 담보하는 역할을 수행함에도 불구하고 국내관광부문은 활성화되지 못하고 있다. 이러한 점은 우리나라의 해외관광객은 2010년-2017년에 연평균 11.3%라는 높은 증가를 보인데 비해 우리나라 국립공원의 탐방객은 연평균 1.5% 성장이라는 초라한 실적을 드러내고 있다는 데서 알 수 있다. 더욱 산악형 국립공원에 대해서는 비교적 많은 연구가 이루어지고 있는데 비해 해상형 국립공원에 대해서는 상대적으로 연구와 관심이 빈약한 편이다. 이에 본고는 변이할당분석과 BCG분석을 이용하여 해상형 국립공원 탐방객의 변동요인을 식별한다. 먼저 변이할당분석을 적용하여 4개 해상형 국립공원 탐방객의 변동을 국립공원 전체에 대한 탐방수요가 개별 국립공원탐방수요에 미치는 국립공원효과, 국립공원 전체에 대한 매력과 해상형 국립공원에 대한 매력의 차이가 개별 국립공원 탐방수요에 미치는 해상형 국립공원효과, 그리고 개별 국립공원과 해상형 국립공원의 탐방수요가 미치는 소위 경쟁력효과와 같은 3개 요인으로 분해한다. 또한 변이할당분석을 정태적 분석과 동태적 분석으로 구분하여 정태적 분석과 동태적 분석의 3개효과가 부호와 크기에서 상당한 차이를 노정한다는 것도 밝힌다. 구체적으로 우리나라 4개 해상형 국립공원의 탐방객 변동을 요인별로 분해하여, 정태적 분석에서는 국가효과와 구성효과가 양의 값으로 4개 해상형 국립공원 탐방객을 증가시키나, 동태적 분석에서는 구성효과의 경우 2013년부터, 국가효과의 경우 2014년부터 음의 부호를 갖는다는 것을 밝힌다. 탐방객이 증가한 오동도, 다도해해상국립공원, 태안해안국립공원은 물론 탐방객이 감소한 변산반도국립공원에서도 개별 국립공원의 경쟁력을 의미하는 지역효과가 가장 큰 영향을 미친다는 것도 보인다. BCG 매트릭스를 적용하여 오동도와 다도해해상국립공원은 star 영역으로 상승한 후star 위상을 유지하며, 변산반도국립공원은 star에서 cash cow와 child로 위상이 변화하여 탐방객 증가가 평균 이상을 유지하고 있는데 비해 태안해안국립공원은 child에서 dog로 추락함을 보인다. 이러한 분석을 통해 4개의 해상형 국립공원 모두에서 지역효과가 탐방객 변동에 가장 큰 영향을 미친다는 것과, 오동도와 다도해해상국립공원의 경쟁력은 우수하나 변산반도 국립공원의 경쟁력은 정체상태에 있으며, 태안해안국립공원의 경쟁력은 하락하고 있음을 밝힌다. BCG분석에서는 오동도와 다도해해상국립공원이 탐방객에서 경쟁력이 있다는 것과 태안해안국립공원에서 가장 큰 경쟁력 향상이 이루어져야 한다는 것도 밝힌다. Tourism is widely considered one of the world's largest and rapidly growing industries. Domestic tourism, however, remains an under-researched theme in many countries involving Korea partly due to the difficulty to track domestic tourism and with governments and policy-makers placing emphasis on the attractive higher expenditures of foreign visitors. It is stated that a vibrant domestic tourism sector can cushion the industry from fluctuations of the international tourism market and bring stability and predictability in the industry. Nature-based tourism to national parks gives us broad benefits such as improved physical and mental health, stress reduction and increased social cohesion. Employment is one of tourism’s main development advantages and its role in promoting economic opportunities for communities adjacent to national parks has long been appreciated. But tourism performance in Korean national parks continues to dwindle and stagger. This paper introduces a shift-share decomposition to break down the tourism to the marine national parks into three components: one measuring national effect, and two other components due to changes in compositional effect and regional effect respectively. While the static shift-share analysis shows that the growth in marine national parks’tourism seems to be due to positive national park effect as well as marine national park effect, the dynamic regional effect appears to have a negative effect on visitors. This paper also employs the positioning analysis on national parks using Boston Consulting Group matrix over the period 2011-2016. The BCG analysis shows that Odongdo and Dadohaehaesang succeed in rising to a star area, Byeonsanbando ranges over a cash cow to a child, but Taeanhaean degrades from a child to a dog area.

경주지역 여고생의 초경과 체성장간의 관계

김준섭,권오구,박진석,오종수,박정현,박제식,안세한,이용환,서정호,신태섭,최영배,김덕수,이관,박수경 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

본 연구는 경주지역 1개 고등학교 3학년 여고생을 대상으로 초경 시작 전인 초등학교 4학년부터 고등학교 2학년까지의 키, 몸무게, 가슴둘레 수치와 초경 연령을 파악하여 여성의 초경이 빠를수록 체성장 속도의 변화가 있을 것이라는 가설을 기초로 두 요인간의 관련성을 파악하고자 시행되었다. 경주시 1개 여자고등학교 3학년생 총 317명에 대해 ㅊ경 나이, 초경시 심리 상태, 초경이 시작되었을 때의 상담 여부와 상담하였던 사람, 부모 신장과 초경전후의 식사 규칙성, 다이어트 경험, 수면시간, 스트레스, 음주/흡연 여부, 질병력 등에 대한 설문 조사를 시행하였고, 초등학교 4학년부터 고등학교 2학년까지의 키, 몸무게, 가슴둘레에 대한 정보는 건강기록부에서 확보하였다. 상기 대상자 중 건강기록부가 분실된 39명, 초경나이에 대해 응답하지 않았던 29명 및 결석 등으로 조사를 하지 못하였던 42명을 제외한 조사 대상자는 206명으로 선정하였다. 대상자들의 초경연령 평균값(Mean±SD)은 13.0±1.11이었고, 초등학교 4학년부터 고등학교 2학년까지의 초경 이후 신장 성장률은 감소하였으며, 초경연령이 빠른 군이 초등학교 때는 신장에 있어서 우위를 차지하나 고등학교에 오면서 신장은 비슷한 수준이 되었다. 초경후 1-2년 사이에 체중과 흉위의 증가율은 감소하였고, 초경연령이 빠른 군이 초등학교와 고등학교 사이에 체중과 흉위에서 모두 우위를 차지하였다. 본 연구의 결과는, 흔히 이차 성징의 시작 시점 혹은 사춘기의 시작 시점으로 보고있는 초경 연령이 청소년기의 성장과 밀접한 관련성이 있고, 특히 체중과 흉위의 성장 속도와 밀접한 관련성이 있음을 시사한다. To understand the onset of menarche in relation to changes in physical growth that take place during female adolescence, especially the changes in height and weight velocity. The 207 senior in one women high school of Kyongju were investigated in April 3 to 8, 2001. We collected the information, relation in the age at menarche, height & weight of parents, regularity of eating, and obesity diet, duration of sleeping, sickness & stress near age at menarche, by self-recording. The status of height, weight & chest circumference between the 4th grade of primary school and the junior of high school was collected by individual Health Record. The results were followed; The average age at menarche was 12.95±1.11 years old and the most frequent age of menarche is 13 years. After menarche, the velocity of height, weight and chest circumference were decreased. The most rapid group of menarche hold dominant position in height during elementary school. As time passed, they dont hold dominant position in height. The most rapid group of menarche get an advantage in the weight and the girth of chest after elementary school. The height of subjects is directly proportional to the height of their parents. These results suggest that the starting age at menestuation can be closely associated with physical growth and development.

설악산 국립공원의 어류분포

장민호,조가익,하진용,정광석,박성배,주기재 한국어류학회 2002 韓國魚類學會誌 Vol.14 No.4

설악산 국립공원지역 산간계류의 17개 지점에서 2000년 6월부터 2001년 6월까지 어류상 및 이화학적 요인을 계절별로 총 4회에 걸쳐 분석하였다. 모든 조사지점은 1~3차의 하천으로 비교적 물리·화학적 교란이 적었으며 하천폭은 5~30 m 정도였다. 채집된 어류는 총 18과 42종 2,557개체였고, Cyprinidae는 16종으로 84.7%의 상대풍부도를 나타냈으며, Gobiidae 4종, 5.0?의 상대풍부도를 보였다. Cyprinidae는 전체 채입종의 37.2%를 나타냈다. 우점종은 Zacco temminck로 10개 지점에서 738개체가 채집되어 28.9%의 상대풍부도를 나타냈으며, 아우점종은 Rhynchocypris kumkangensis와 Z. platypus로 각각 4개 지점 648개체(25.3%)와 7개 지점 344개체(13.5%)로 나타났다. 한국고유종(Korean endemic species)은 모두 4과 11종 781개체로 30.5%의 상대풍부도를 나타냈으며, 고유화 빈도는 25.6%로 한국의 평균 고유화 빈도와 유사하게 나타났다. 본 조사에서 외래어는 채집되지 않았다. 국립공원 내에 서식하는 어류의 다양성 유지와 회복을 위해서는 공원 내는 물론 경계지역 하천의 체계적인 관리가 요구된다. The fish fauna of mountain streams in the Seorak National Park area was investigated from June 2000 to June 2001 (4 times). All 17 sites were relatively undisturbed 1st to 3rd order streams. A total of 2,557 individuals were collected and classified into 17 families and 43 species. Cyprinidae accounted for 37.2% (16 species) of the total fish species and 84.7% (2,165 ind.) of the total abundance. Subdominant families were Gobiidae (4 species, 5.0%) and Balitoridae (3 species, 3.4%). Zacco temmincki (RA 28.9%, 10 sites) dominated. Subdominant species were Rhynchocypris kumkangensis (25.3%, 4 sites) and Zacco platypus (13.5%, 7 sites). Eleven of the species are endemic to Korea (4 families, 30.5%). Exotic species were not collected in this survey. Fish diversity was higher in streams around the boundary area than in the national park. Therefore, management of streams in the boundary area to protect the fish biodiversity can be efficiently conducted. Habitat degradation should be reduced for the conservation and restoration of fish diversity.

Protein kinase A-induced phosphorylation at the Thr154 affects stability of DJ-1

Ko, Yeon Uk,Kim, Su-Jeong,Lee, Juhyung,Song, Min-Young,Park, Kang-Sik,Park, Jun Bae,Cho, Hyun-Soo,Oh, Young J. Elsevier 2019 Parkinsonism & related disorders Vol.66 No.-

<P><B>Abstract</B></P> <P><B>Introduction</B></P> <P>Most cases of Parkinson's disease (PD) are sporadic, but genetic variations have been discovered in PD patients. PARK7/DJ-1 is a known cause of early-onset autosomal-recessive PD and is implicated in neuroprotection against oxidative stress. Although several post-translational modifications of DJ-1 have been proposed, phospho-modification of DJ-1 and its functional consequences have been less studied.</P> <P><B>Methods</B></P> <P>Putative phosphorylation sites of DJ-1 were determined by liquid chromatography-tandem mass spectrometry (LC-MS/MS analysis). Subsequently, phosphorylation site of DJ-1 was confirmed by <I>in vitro</I> kinase assay and cell-based pull-down assay. Impaired dimer formation of phospho-null mutant was measured using DSS crosslinking assay and immunoprecipitation assay. To evaluate physiological consequences of this event, protein stability of DJ-1 WT and DJ-1 phospho-null mutant were compared using cycloheximide chase assay and ubiquitination assay.</P> <P><B>Results</B></P> <P>Here, we showed that DJ-1 directly bound to the catalytic subunit of protein kinase A (PKAcα). We found that PKAcα is responsible for phosphorylation of DJ-1 at the T154 residue. Interestingly, dimerization of DJ-1 was not detected in a DJ-1 T154A mutant. Furthermore, stability of the DJ-1 T154A mutant was dramatically reduced compared with that of wild-type DJ-1. We found that DJ-1 T154A was prone to degradation by the ubiquitin proteasome system (UPS).</P> <P><B>Conclusion</B></P> <P>We identified a novel phosphorylation site of DJ-1. Furthermore, we determined protein kinase A that is responsible for this posttranslational modification. Finally, we demonstrated physiological consequences of this event focusing on dimerization and protein stability of DJ-1.</P> <P><B>Highlights</B></P> <P> <UL> <LI> PKAcα phosphorylates PARK7/DJ1 at the Thr154 residue. </LI> <LI> Disruption of Thr154 phosphorylation is linked to a lower stability. </LI> </UL> </P>

제한효소 SacⅡ의 Isoschizomer인 SexⅢ를 생성하는 토양 Streptomyces 균주의 수리 동정

배무,서원나,박정옥,김형태,이계준 이화여자대학교 생명과학연구소 1993 생명과학연구논문집 Vol.4 No.-

제한효소인 SexⅢ을 생성하는 Streptomyces속의 한 균주(Streptomyces sp.58)를 토양으로부터 분리하여 형태적 관찰 및 수리동정을 실시하였다. 50여개의 분류 단위 형질을 분석하였고 이 실험 결과를 TAXON program에 적용하여 종의 수리 동정을 실시하였다. 그 결과 분리균은 Streptomyces의 제5주군집에 속하는 것으로 나타나 Streptomyces exfoliatus의 한 균주로 동정하였다. Numerical identification was carried out for an isolate of Streptomyces sp. 58 producing a new restriction endonuclease SexⅢ. Fifty taxonomic unit characters were tested and the data were analyzed numerically using the TAXON program. The isolate was identified to the major 5 or Streptomyces. Therefore, it was concluded that the isolate was identified to be a member of Streptomyces exfoliatus.

사지의 급성동맥 색전증에 대한 응급동맥 색전제거술

박철완,원형섭,박정배,이근,조상훈,표창해,김상일 대한응급의학회 1996 대한응급의학회지 Vol.7 No.2

Acute arterial occlusion of the extremities is often a surgical emergency and is due mostly to arterial embolus. It has infrequently been reported in the emergency department. Cardiac embolism is most commonly the result of atrial fibrillation secondary to valvular heart disease followed by ischemic heart disease. The emergency arterial embolectomy by Fogarty balloon catheter works well when the cause of occlusion is cardiac embolus obstructing normal vessels in a patient with valvular heart disease. Recently we met some patients with acute critical ischemia of the extremities due to arterial emboli in our emergency department. On physical examination, they all had symptoms of 5"P"s(pain, pallor, pulselessness, paresthesia, paralysis). After emergency arterial embolect omy, immediate improvement was observed in all patients. They were discharged within 1 week. We report our experiences with the review of literatures.

내시경으로 치료한 담석성 췌장염을 동반한 담도회충증 1예

박영주,김영수,최원,신용운,이돈행,김범수,전정배,조현근 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.4

3극관형 진공게이지 제작 및 최적조건 결정

박래준,배정운,박종윤 성균관대학교 기초과학연구소 1996 論文集 Vol.47 No.2

B-A type hot cathode ionization gauge to measure the UHV(Ultra High Vacuum) was generally used in these days. Whereas, HV(High Vacuum) is still major pressure region in the application of vacuum to the industry. Conventional triode gauge(CTG) is used mainly for measurement in HV region, thus we constructed the modified triode gauge(MTG). In order to find the optimum condition of MTG. We measured I_e vs U_c, I_e vs U_g and U_c, I_e vs U_g and P, I_i vs U_g and P as well as I_i vs P because I_i is depend on pressure(P), filament potential(U_c), grid potential(U_g), filament heating power(Hp), and emission current(I_e). The good linearity of I_i P curve is obtained from ∼10^-6 to ∼10^-4 torr at 5A heating current, 200V grid potential, 40V filament potential and below ∼10^-7 torn at 4.6A.

위암세포에 의한 종양침윤 림프구의 면역반응 억제기전에 관한 연구

박정규,송규상,서광선,최정목,배진선,장일성,윤완희,노승무,조은경,백태현 大韓免疫學會 1995 大韓免疫學會誌 Vol.17 No.3

Tumor-infiltrating lymphocytes ('1°ILs) interact most closely with tumor cells and thus are more likely to reflect tumor host interactions accurately. But it is unknown whether such T cells are nonspecific inflammatory cells or a subset of specific host immune responses. In this study, there was no clear correlation between the infiltration of T lymphocytes in stomach cancer and the overexpression of c-ErbB-2 or increasing class I MHC expression on tumor cells. A positive correlation was seen between the presence of TILs in the tumor and tumors with diploidy by flow cytometric DNA analysis. The proliferative responses of Ills stimulated with IL-2, anti-CD3 mAb, or both were examined. When compared to normal mucosal-associated lymphoid tissue lymphocytes, the proliferative response of TILs to high dose IL-2 was minimal. A similarly poor response to anti-CD3 mAb plus IL-2 was also observed. The freshly isolated TILs exhibit reduced ability to proliferate in response to IL-2, anti-CD3 mAb or both. The microenvironment of the tumor suppresses the proliferative capacity of the TILs. The mechanism of this suppression remains unknown. It could be mediated by suppressor cells, by soluble substances within the tumor, or both. To examine this question, supernatants of stomach cancer cells (SNSNU-1) were tested for the presence of immunosuppressive factors. Human peripheral blood T-cells and tumor-draining lymph node lymphocytes (TDLNL) were incubated for 3 days with SNSNU-1 and then assessed for proliferative responses to PMA, anti-CD28 mAb, or both and for the inducibility to express IFN- r or IL-4 mRNA to PMA. Peripheral blood T-cells pretreated with SNSNU-1 were unable to proliferate in response to PMA, anti-CD28 mAb or both. SNSNU-1 also produces inhibitory activities of TDLNL proliferative response to PMA or anti-CD28 mAb and PMA (49%, 52%, respectively). In contrast, culture supernatants obtained from HEp-2, K562 or Daudi showed normal proliferative responsiveness of peripheral blood T-cells and TDLNL by PMA, anti-CD28 mAb or both.

전계발광소자를 위한 강유전체 박막의 제작 및 특성

배승춘,김정환,김호운,박성근,김기완 경북대학교 센서기술연구소 1997 센서技術學術大會論文集 Vol.8 No.1

PLT and PLZT feroelectric thin films were fabricated on ITO substrate by rf magnetron sputtering. Pressure was 30mTorr, rf power was 180W and substrate temperature was varied from room temperature to 500℃. In this case, PLT had the highest dielectric constant of 120 at 500 ℃, oppositly PLZT had the highest dielectric constant of 312 at room temperature. I-V characteristics of PLZT film were shown that leakage current of PLZT film deposited at room temperature was below 3μA at 100V.