http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
진폐증 환자에서 발생한 폐렴에서의 정주용 인 면역글로불린의 투여 효과
문제혁,정진숙,김경아,임영,남호우,한중수 大韓産業醫學會 2002 대한직업환경의학회지 Vol.14 No.2
목 적 : 진폐중환자에서 대식세포의 기능저하, 폐섬유화로 병소로의 약물 침투의 저조, 면역계의 변화가 있는 것으로 알려져 있다. 이로 인하여 폐렴치료의 어려움이 있어 중증 감염증에 효과가 있는 것으로 알려져 있는 IgG를 진폐증 환자에서 동반된 폐렴의 치료로 항생제와 함께 투여하였을 때 효과를 보고자 하였다. 방 법 : 항생제와 IgG를 함께 투여하는 투여군과 항생제만 단독 투여하는 대조군을 무작위로 선정하였다. 약물 투여전과 투여후 2·4·6·8일에 객담검사, 체온, 동맥혈산소분압, 말초혈액 백혈구와 간상중성구를 검사하여 1점부터 4점까지 점수를 부여하여 두 군간에 비교하였다. 결 과 : 투여군은 27명있었고, 대조군은 18명이었다. 두 군간에 나이, 진폐병형, 심폐기능장해도, 객담에서의 균배양여부가 유의한 차이를 보이지 않았다. 1. 이들 인자들을 고려하지 않았을 때, 투여군에서 대조군보다 임상평가 점수가 낮아지는 경향을 보였다. (p=0.083). 2. 나이가 60세 미만인 경우에는 투여군이 대조군보다 임상평가점수가 유의하게 적었다(p<0.01). 3. 단순진폐증인 대상자인 경우에는 투여군에서 대조군보다 임상평가점수가 낮아지는 경향을 보였다(p=0.077). 4. 심폐기능장해도에 따라 두 군간에 임상평가점수의 유의한 차이는 없었다. 5. 객담배양검사의 결과에 따라 두 군간에 임상평가점수의 유의한 차이는 없었다. 결 론 : 나이가 60세 미만으로 상대적으로 젊고, 단순진폐증인 경우에는 진폐증환자에서 병발한 폐렴의 치료에 항생제와 병용한 IgG의 효과가 있을 것으로 예상된다. Objectives : It is well known that pneumoconiotic patients experience impairments of macrophage function, as well as poor penetration of drugs into the fibrotic nodules and the immune system. Resultantly, pneumonia is frequently involved in pneumoconiotic patients and its treatment is not easy. Therefore, we conducted a clinical evaluation of immunoglobulin G which is known to be effective in severe infectious diseases. Methods : We randomly selected 45 pneumoconiotic patients with pneumonia and classified them into 2 groups. The experimental group (IgG group) was scheduled to receive antibiotics and igG (5 g I.V./day for 7 days). The control group was treated with antibiotics alone. Sputum gram stain (counts of WBCs and microorganisms), body temperature, arterial oxygen tension, and counts of peripheral venous blood leukocytes and band neutrophils were used as markers to assess the response effect therapy at time periods of 0, 2, 4, 6, and 8 days after completion of therapy. We compared the clinical scores between the two groups. Results : The experimental IgG treated group was composed of 27 patients, and the control group comprised 18 patients. There was no statistical differences between two groups in terms of age, pneumoconiotic profusion, impairment degree of pulmonary function, or frequency of pathogen isolation in the sputum before medication. The experimental IgG treated group showed lower clinical scores as compared with the control group (p=0.083). Conclusions : These results suggest that IgG infusion with antibiotics will have an effect on pneumonia therapy in pneumoconiosis patients that are under 60 years and exhibit simple pneumonoconiois.
高X線 吸收유리에 있어서 BaO, SrO의 含量變化가 液相溫度에 미치는 影響
李卿喜,梁在翊,金德文,姜元浩 明知大學校 産業技術硏究所 1987 産業技術硏究所論文集 Vol.6 No.2
The liquidus temperature was observed according to the change of content BaO 6 W/O ~ 12W/O and SrO 1 W/O~4W/O in R₂O-PbO-Al₂O₃- (BaO+SrO+SiO₂) glass system. The liquidus temperature varied between 810°C ~ 950°C in these glasses. The effect of BaO & SrO content to the liquidus temperature of the glasses are as follows. 1. The variation of the liquidus temperature were remarkable by the content of SrO in the range of BaO contents from 6 W/O to 8 W/O. 2. The minimum liquidus temperature is located at the composition of BaO 8 W/O SrO 4 W/O SiO₂ 68 W/O.
Histopathology of inflammatory nail disorders
( Je-ho Mun ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1
Histopathology is fundamental in establishing a diagnosis of nail disorders. Although nail biopsy is not a primary test as it has side-effects, it is performed in difficult, long-standing, recalcitrant cases, or cases that need unequivocal diagnosis. In this presentation, the histopathologic features of inflammatory nail disorders will be discussed. The presenter's experience as well as literature review will be presented for cases such as trachyonychia, nail psoriasis, lichen planus, lichen striatus, contact dermatitis, etc.
( Je Ho Mun ),( Hyun Je Park ),( Hoon Soo Kim ),( Su Han Kim ),( Hyun Chang Ko ),( Byung Soo Kim ),( Moon Bum Kim ) 대한피부과학회 2012 Annals of Dermatology Vol.24 No.1
Lichens striatus (LS) is an acquired, self-limiting inflammatory dermatosis that follows the lines of Blaschko. The etiology of the eruption is unknown, but several theories have been proposed with focus on environmental factors, viral infection, cutaneous injury, hypersensitivity, and genetic predisposition. We describe a 19-year-old woman who developed a unilateral linear eruption 17 months after allogenic peripheral blood stem cell transplantation. Histopathology revealed features, which were consistent with LS. To the best of our knowledge, our patient is the first case describing the appearance of LS occurring after allogenic stem cell transplantation. We speculate that this condition represents an unusual form of localized, chronic graft- versus-host disease. (Ann Dermatol 24(1) 87∼89, 2012)
P050 : Dermoscopic patterns of m alignant melanomas on the trunk and extremities in Koreans
( Je Ho Mun ),( Woo Il Kim ),( Gun Wook Kim ),( Hyun Ho Cho ),( Won Jeong Kim ),( Margaret Song ),( Hoon Soo Kim ),( Hyun Chang Ko ),( Byung Soo Kim ),( Moon Bum Kim ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: Dermoscopy has been proven to increase diagnostic accuracy of malignant melanomas. However, dermoscopic features of melanomas in Asians have been scarcely reported. Objectives: To investigate dermoscopic patterns and evaluate diagnostic algorithmic approach in Korean patients with melanomas in trunk and extremities. Methods: Dermoscopic evaluation of histopathologically confirmed melanomas at 2 university hospitals from 2007 to 2014 was performed. Dermoscopic scores were evaluated using various dermoscopic algorithmic methods. Results: Sixteen patients with 16 primary melanomas and 5 patients with 15 metastatic melanomas were included. In primary melanomas, several dermoscopic melanoma-associated features were found: blue-white veil (76%), blotches (62%), atypical dots/globules (52%), ulcer (48%), atypical pigment network (43%), irregular peripheral streaks (43%), atypical vessels (38%), shiny white lines (29%), and regression (10%). Mean scores of 7-point checklist, revised 7-point checklist, 3-point checklist, ABCD rule, and CASH algorithm were 6.3, 4.1, 2.6, 7.6, and 10.9. In metastatic melanomas, the algorithmic approaches were not accurate as the mean scores were 1.7, 0.9, 0.8, 2.0, 4.1. Conclusion: Dermoscopy can be useful in diagnosingmalignant melanomas in trunk and extremities in Koreans. Dermoscopic algorithmic approaches were useful in detecting primary melanomas; however, they were not precise in identifying metastatic melanomas.
FC 2-6 : Clinical and dermoscopic characteristics of extramammary paget``s disease
( Je Ho Mun ),( Sung Min Park ),( Hyun Ho Cho ),( Won Jeong Kim ),( Mar Garet Song ),( Hoon Soo Kim ),( Hyun Chang Ko ),( Byung Soo Kim ),( Moon Bum Kim ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: Extramammary Paget`s disease (EMPD) is a rare cutaneous, intraepithelial adenocarcinoma. Diagnosis is often delayed because of the various clinical presentations and the rarity of the disease. Dermoscopy improves diagnostic accuracy of pigmented and non-pigmented skin tumors. However, dermoscopic features of EMPD had not been thoroughly investigated. Objectives: To evaluate the clinical and dermoscopic characteristics of EMPD. Methods: Clinical and dermoscopic images of 32 histopathologically confirmed EMPD were analyzed. Results: EMPDs were clinically characterized by erythematous patches (100%), scales (62.5%), ulcer (37.5%), nodules (12.5%), focal hyperpigmentation (18.8%), and hypopigmentation (9.4%). Dermoscopically, the following features were detected: erythematous background coloration (100%), surface scales (96.9%), vascular patterns (90.6%), ulcers (43.8%), structureless white areas (12.5%), shiny white lines (12.5%), and pigmentary structures (34.4%). Among vascular patterns, dotted vessels were frequently observed (53.1%), followed by glomerular vessels (21.9%), and polymorphous vessels (12.5%). Conclusion: The results of our study suggest that there are distinctive clinical and dermoscopic features of EMPD. Recognition of the characteristic features of EMPD can facilitate accurate diagnosis of EMPD, and may reduce misdiagnosis.