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( Jaya Shree Jena ),( Nilotpala Pradhan ),( Rati Ranjan Nayak ),( Bishnu P Dash ),( Lala Behari Sukla ),( Prasanna K Panda ),( Barada K Mishra ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.4
Bionanotechnology has revolutionized nanomaterial synthesis by providing a green synthetic platform using biological systems. Among such biological systems, microalgae have tremendous potential to take up metal ions and produce nanoparticles by a detoxification process. The present study explores the intracellular and extracellular biogenic syntheses of silver nanoparticles (SNPs) using the unicellular green microalga Scenedesmus sp. Biosynthesized SNPs were characterized by AAS, UV-Vis spectroscopy, TEM, XRD, FTIR, DLS, and TGA studies and finally checked for antibacterial activity. Intracellular nanoparticle biosynthesis was initiated by a high rate of Ag+ ion accumulation in the microalgal biomass and subsequent formation of spherical crystalline SNPs (average size, 15-20 nm) due to the biochemical reduction of Ag+ ions. The synthesized nanoparticles were intracellular, as confirmed by the UV-Vis spectra of the outside medium. Furthermore, extracellular synthesis using boiled extract showed the formation of well scattered, highly stable, spherical SNPs with an average size of 5-10 nm. The size and morphology of the nanoparticles were confirmed by TEM. The crystalline nature of the SNPs was evident from the diffraction peaks of XRD and bright circular ring pattern of SAED. FTIR and UV-Vis spectra showed that biomolecules, proteins and peptides, are mainly responsible for the formation and stabilization of SNPs. Furthermore, the synthesized nanoparticles exhibited high antimicrobial activity against pathogenic gram-negative and gram-positive bacteria. Use of such a microalgal system provides a simple, cost-effective alternative template for the biosynthesis of nanomaterials in a large-scale system that could be of great use in biomedical applications.
Schwannoma of the uterine cervix: a rare case report
Biswajit Dey,Sairem Mangolnganbi Chanu,Jaya Mishra,Evarisalin Marbaniang,Vandana Raphael 대한산부인과학회 2019 Obstetrics & Gynecology Science Vol.62 No.2
Schwannomas are neurogenic tumors, which are among the most varied tumors with respect to morphology, clinicalassociations, and presentations; they occur in a wide variety of sites. The uterine cervix is a rare site of occurrence andonly 15 cases of schwannomas of the uterine cervix, including 5 benign and 10 malignant cases, have been reportedto date. Thus, schwannomas of the uterine cervix may pose diagnostic difficulty. Here, we report a case of benignschwannoma of the uterine cervix in a 37-year-old female, who presented with vaginal spotting.
Metachronous Cancer of Breast and Adenocarcinoma of Cervix: A Rare Case Report
( Nalini Sharma ),( J Lalnunnem Thiek ),( Das Rituparna ),( Jaya Mishra ),( Ahanthem Santa Singh ) 대한폐경학회 2017 대한폐경학회지 Vol.23 No.2
The occurrence of a second primary cancer in a cancer survivor is well documented. It may be synchronous or metachronous. Incidence of metachronous cancer involving cervix is 0.82% to 1.33%. One such metachronous cancer is that of breast and cervix. We present a case of a woman who received tamoxifen for invasive ductal cancer of breast following a modified radical mastectomy and subsequently developed adenocarcinoma of cervix after six month of tamoxifen therapy. The role of tamoxifen in pathogenesis of cervical cancer and that of human papillomavirus infection in pathogenesis of both cancer of cervix and breast cancer has been well recognized. In our patient, the adenocarcinoma of cervix (rare occurrence) which is likely due to six month of tamoxifen therapy is a perplexing question. Women diagnosed and treated for breast cancer need to be followed up for development of other metachronous gynecological cancers. (J Menopausal Med 2017;23:131-134)