Could cluster of risk factors predict clinical outcome in patients with acute myocardial infarction?

( Sang Mi Park ),( Hong Nyun Kim ),( Se Yong Jang ),( Myung Hwan Bae ),( Dong Heon Yang ),( Hun Sik Park ),( Yongkeun Cho ),( Shung Chull Chae ),( Jang Hoon Lee ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1

Purpose: Conventional risk factors are differently contributed to short-term prognosis of acute myocardial infarction (AMI); hypertension and diabetes increase adverse outcome, whereas hyperlipidemia, smoking, and obesity paradoxically decrease adverse outcome of post-MI patients. The aim of this study is to assess whether cluster of conventional risk factors, PARADOCS (Pressure of ARtery Abnormality, Diabetes, Obesity, Cholesterol, Smoking) score, would improve the ability to predict major adverse cardiac events (MACEs) in patients with AMI. Methods: Between November 2005 and July 2011, 24,020 patients (17,232 men; mean age=63.0±12.8) with AMI were analyzed from Korean AMI registry. PARADOCS score was calculated as follows; [number of non-paradoxical risk factors (NRF) -number of paradoxical risk factors (PRF)]+3 in which non-paradoxical risk factors are hypertension and diabetes, and paradoxical risk factors are the rest. The 1-year MACEs were defined as death and non-fatal MI. Results: NRF including hypertension and diabetes were present in 49.6% and 27.0%, whereas PRF including hyperlipidemia, smoking, and obesity were present in 12.3%, 43.0%, and 34.6%, respectively. During the follow-up, 1,409 (5.9%) MACEs occurred. PARADOCS score was significantly higher in patients with 1-year MACEs (3.38±1.03 versus 2.81±1.08, p<0.001). In Cox proportional hazards model, PARADOCS score was an independent predictor of 1-year MACEs (hazards ratio 1.26, 95% confidence interval 1.18-1.34; p<0.001) after adjusting for confounding variables. Patients were categorized into 3 groups according to the PARADOCS score; PARADOCSLOW (0-1, n=2,446), PARADOCSMID (2-3, n=14,594), and PARADOCSHIGH (4-5, n= 6,980). Kaplan-Meier survival curve showed that there were significant differences in the 1-year MACEs among three groups including 3.5% in PARADOCSLOW, 8.5% in PARADOCSMID, and 16.4% in PARADOCSHIGH, respectively (long-rank p<0.001). Conclusions: In post-MI patients, conventional risk factors are differently associated with short-term prognosis, and score of these risk factors, PARADOCS score, can provide useful prognostic information to clinicians.

마우스에서 조합시험법에 의한 고려홍삼의 생식발생독성 평가

김미라, 박동선, 장자영, 신선희, 이예은, 백인정, 연정민, 이세라 , 남상섭, 황방연, 노재섭, 김순선, 조대현, 남상윤, 이범준, 김윤배, 윤영원 충북대학교 동물의학연구소 2006 Journal of Biomedical and Translational Research Vol.7 No.1

본문참조

유기 전이 금속의 Hydroboration 에 관한 연구

박미영,정장훈 명지대학교 자연과학연구소 2000 자연과학논문집 Vol.19 No.-

(μ-H)2Os3(CO)10 [1]은 전자적으로 불포화 상태에 있어 반응성이 매우 좋은 클러스터이다. 이런 오스윰 클러스터에 B10H14, B10H122L(L=CH3CN, Et2S, Me2S), Borane〈BH3·L(L: Lewis base=Et3N, Me3N, (C6H5)3P pyridine)) 등의 화합물을 첨가시켜 Os-B결합 형성을 유도하고 리간드의 재배치를 통해서 합성되는 다양한 클러스터들을 연구하였다. 그 결과, (μ-H)2Os3(CO)10과 BH3 ·N(C2H5)3를 반응시켜 이미 발표된 borylidyne cluster (μ-H)2Os3(CO)9(μ-H)2BH를 합성했다. 그리고 상온에서 (μ-H)2Os3(CO)10과 BH3·N(CH3)3 반응시켜 tetra osmium boride cluster를 합성했으며 기존의 방법보다는 수득률이 높았다. 한편, Osmium boride cluster화합물의 특성은 1H, 11B NMR과 IR spectroscopies로 조사하였다. Hydroboration of the unsaturated cluster (μ-H)2Os3(CO)10 has been extensively studied. The reactions of the unsaturated cluster (μ-H)2Os3(CO)10 with various boranes such as BH3·L {L; N(C2H5)3, N(CH3)3, PPh3, C6H5N, Me2S}, B10H14 and B10H12·2L (L; CH3CN, C6H5N, Me2S) effectively resulted in the hydroboration of the osmium cluster. The products formed depended upon the reaction conditions employed. The previously reported borylidyne cluster (μ-H)2Os3(CO)9BH3 was formed in 80% yield when the reaction of (μ-H)2Os3(CO)10 with BH3·N(C2H5)3 occurred. On the other hand, it was reported that the reaction of (μ-H)2Os3(CO)10 with BH3, formed from B2H6 in the presence of N(C2H5)3, produced another borylidyne cluster (μ-H)3Os3(CO)9(BCO). The hydroboration of (μ-H)2Os3(CO)10 with BH3·N(CH3)3 at room temperature produced tetra-osmium boride cluster HOs4(CO)12BH2 in more yield than the earlier synthetic procedure. The osmium boride clusters were characterized by 1H and 11B NMR and IR spectroscopies.

목재 건조공정 배기가스의 특성에 관한 연구

장정국,박동근,김미란 東西大學校 2001 동서논문집 Vol.7 No.-

This study was performed to provides the characteristics of flue gas producted from wood drying process. Generally, the flue gas producted from wood drying process was elutriated with a large amount of moisture and odorous compounds such as BTX and ethanol. Therefore, it is very difficult to select and design of flue gas control devices. In order to optimum design and selection of control devices, have to investigate the various parameters such as temperature, moisture contents and flow rate of flue gas. When the wood is almost dry(<10% moisture), the moisture contents of flue gas were very high (about 18.2 V/V%). It is equivalent to 320 ton/day moisture as 1100 ton wood/day induce to the drying process. The temperature of flue gas ranges from 140℃ to 150℃ in each dryer stack with exception of the input site of wood(about 110℃). Thevelocity of flue gas In each stack ranges from 1.7 to 9.7 m/sec. About 40 VOCs in the flue gas were analyzed, and the concentrations of major VOCs(ppm) were as follows respectively; benzen: 0.054∼0.052, toluene: 1.011∼2.547, ethylbenzen: 0.472∼2.023, m,p-xylene: 0.504∼3.245, styrene: 0.015∼0.148, o-xylene : 0.271∼1.097, ethanol: 11.2∼32.5, α-pinene: 0.908∼10.578, β-pinene: 0.982∼14.278.

광교산 등산객들의 특징과 시설 만족도

박장근,이원희,장미영 명지대학교 예체능연구소 2000 藝體能論集 Vol.11 No.-

본 연구는 수원시 광교산을 이용하는 등산객을 대상으로 등산시설의 만족도 조사를 하였으며. 광교산 등산시설에 대한 마케팅 전략을 제시하는데 목적을 두었다. 설문조사를 위하여 3개 등산코스에서 총206명을 대상으로 실시하여 다음과 같은 결과를 도출하였다. 본 연구의 결과 시설 수, 시설위치 부분에서는 대체적으로 긍정적 경향으로 나타났지만 시설 수에 있어서는 20대의 집단에서 부정적으로 나타났다. 또한 시설관리, 홍보활동 부분에서는 보통보다 낮은 만족도를 나타내어, 광교산 관리담당기관이 등산객을 위한 현실적이고 효율적인 관리·운영 프로그램 개발이 필요할 것으로 사료된다. 등산객들의 선호도 및 만족도를 조사함으로써 상이한 세분시장에 상응하는 마케팅전략이 제시될 수 있을 것이다. 마케팅 대안 및 차 후 연구의 방향이 제시되었다.

‘숙명역사관’뮤지엄 아이덴티티 개선을 위한 마케팅, 디자인 전략 수립 -특별 기획전, 홍보, 기프트 샵을 중심으로-

박민지,박한빛,서예원,이진민,장미정,이성애 숙명여자대학교 산업디자인연구소 2017 숙명디자인학 연구 Vol.24 No.-

본 연구는 디자인과 마케팅이 이분법적으로 나누어질 수 없음을 인식하고, 디자인과 마케팅을 융합하여 스페이스 디자인 마케팅을 통한 뮤지엄아이덴티티를 구축하는 일련의 프로세스를 제안하는데 목적이 있다. 본 연구는 2017년 3월~6월 총 15주간 숙명여자대학교 환경디자인과 ‘브랜드·스페이스·마케팅’수업에 서 진행된 결과물로서 작업물을 정리하였다. 본 연구의 범위는 4개(物, 事, 人, 場)의 주제 중, 장소(場)를 중심으로 ‘숙명역사관’의 그래픽, 제품, 공간을 개발하는 브랜드 매뉴얼과 연관하여 한정한다. 이에 본 연구는 ‘숙명역사관’이 가지고 있는 역사적 컨텐츠와 가치를 통해 현재 상황과 문제점을 분석하였다. 그 결과 ‘숙명역사관’의 다양한 마케팅 전략을 제시하고 이에 따른 디자인 전략과 해결 방안을 통해 디자인과 마케팅의 융합을 꾀하였다. 아울러 SWOT 분석을 통해 로고, 명함부터 새로 기획하는 숙명역사관 기프트샵, 인테리어디자인, 디스플레이, 공간연출과 그 안의 제품디자인에 이르기까지 일관성과 통일성을 추구했다. 끝으로 본 연구는 뮤지엄아이덴티티 구축을 위한 창의적 디자인 프로세스를 고찰하며, 이를 바탕으로 개발 매뉴얼을 총체적으로 정리함에 있어서 뮤지엄 브랜딩의 기초 자료로 활용될 것으로 기대된다.

무선 전력 전송을 위한 고조파를 제거한 H모양 안테나 설계

장미희,이정남,박종권 한밭대학교 정보통신전문대학원 2005 정보통신전문대학원 논문집 Vol.3 No.1

본 논문에서는 2.45GHz 무선 전력 전송에 사용되는 H형태의 고조파 제거용 패치 안테나를 설계하였다. 제안된 안테나의 세부적인 설계와 측정결과를 설명하였고 논의하였다. 제안된 안테나는 유전율이 4.5이고 두께가 0.762mm인 TMM4 기판을 사용하였다. 제안된 안테나는 시뮬레이션 결과 2차, 3차 고조파 성분은 제거되었다. In this paper, we have designed a harmonic suppression H-shaped antenna using wireless power transmission system for 2.45GHz. Details of the proposed antenna designed and measured results are presented and discussed. It is designed to work an a substrate TMM4 of thickness 0.762mm and relative permittivity 4.5. From the simulation results, the second and third harmonics were eliminated.

서울 시내 4년제 남자 대학생의 우울과 흡연량, 흡연기간, 니코틴 의존도와의 관계

박지영,박소영,이미숙,백수진,신의경,예혜련,오승진,장윤정,조혜진,김수지 이화여자대학교 간호과학대학 2003 이화간호학회지 Vol.- No.37

Background: With reports on the relation between smoking and depression appearing since 1980, it has become clear that depression is one of the psychodynamics of smoking, though there has been little or no progress made in the study of whether or not there is indeed a relation between depression and nicotine dependence. Purpose: The purpose of the study was to investigate the effects of depression on the amount and period of smoking and nicotine dependence among university man student smokers. Method: In periodical examination between 14 and 21, May, 2003, using 170 university male. The CES-D(Center for Epidemiologic Studies Depression) Scale and the FTQ(Fagerstrom Tolerance Qustionnaire) were utilized to measure the level of depression and nicotine dependency. The amount of smoking was calculated based on the number of cigarette used. Result: Results indicated that depression had something to do with amount of smoking. Nicotine dependence also was related to depression but total value was relatively low. finally the period of smoking had nothing to do with depression. Conclusion: The results of this study revealed that the amount of smoking of university man student smokers was very high. Both the amount of smoking and nicotine dependence were affected by levels of depression. Accordingly psychiatric nursing access such as emotional support is needed to manage depression and decrease smoking.

DS-COMA 다중 사용자 검출기의 성능 평가

박미선,장은영,변건식 동아대학교 정보기술연구소 2003 情報技術硏究所論文誌 Vol.11 No.1

MUD(Mu1tiUser Detector) is the best way of a solution to neai-far problem in CDMA system. Synchronous MUD is classified into linear and nonlinear. Linear MUD includes decorrelator, MMSE, LMS, RLS. Nonlinear MUD has SIC, PIC, DFD, this paper compared and evaluated performance of MUD'S features and confirmed that Blind MUD is used without training sequence.

Carbon tetrachloride를 투여한 rat의 hepatic lipid 축적에 미치는 vitamin E의 효과에 관한 연구

박은주,이경연,이미영,이외숙,장재정,정귀은,최진희 曉星女子大學校 藥學大學 學生會 1988 曉星藥誌 Vol.4 No.-

The present studies were undertaken to evaluate the effect of vitamin E, CCl_4 on the change of hepatic triglyceride, hepatic cholesterol, hepatic phospholipid in male rat. The result obtained from this study were summarised as follows: 1. Hepatic phospholipid of CCl_4 treated rat was increased in proportion to CCl_4 dosage but after concomitant injection(I.P) of vitamin E and CCl_4, hepatic phospholipid was significantly decreased in comparison to that of CCl_4 alone injection. 2. There was no effect on hepatic cholesterol concentration either CCl_4 alone injection(I.P) or concomitant injecton(I.P) of vitamin E and CCl_4. 3. Hepatic triglyceride of CCl_4-treated rat was significantly increased in comparison to that of normal rat but hepatic triglyceride of rat concomitant injection of vitamin E and CCl_4 was significantly decreased in comparison to that of CCl_4 alone injection.