이용자 만족도에 영향을 미치는 수변형 생태공원 계획요소 규명 - 경인 아라뱃길 두물머리 생태공원을 대상으로 -

윤상훈(Yoon, Sanghoon),박재영(Park, Jaeyoung) 인천연구원 2015 도시연구 Vol.- No.9

본 연구는 경인 아라뱃길의 수변형 생태공원을 대상으로 이용자 만족도에 영향을 미칠 수 있는 계획요소를 규명하고자 하였다. 수변형 생태공원은 수변공간과 생태공원이 결합된 형태로 새롭게 연구되고 있는 공원의 형태이다. 분석방법으로는 계획요소가 많은 만큼 다중공선성에 대한 문제를 해결하기 위해 전통적인 다중회귀분석이 아닌 PLS회귀분석을 활용하였다. 분석결과, 수변형 생태공원의 이용만족도에 가장 큰 영향을 미치는 계획요소는 사람들간의 교류공간(커뮤니티 공간)(VIP값 : 1.242)인 것으로 나타났다. 또한, 생태공원으로의 접근편리성(1.138), 생태습지의 원래대로의 보전정도(1.108), 수변의 다양한 형태(1.051), 안내시설(1.036), 다양한 동식물 서식환경 제공·보호(1.025), 훼손된 생태계의 재생 및 복원(1.016), 생태공간들간의 접근성(1.007)순으로 VIP값이 1.0이상-1.2미만으로 중요하게 영향을 미치는 변수로 도출되었다. 본 연구의 결과, 향후 수변형 생태공원의 이용자 만족도를 높이기 위해서는 생태적 계획요소의 적절한 활용과 함께 이용자들의 교류 활성화 및 커뮤니티 의식 제고를 위한 공간조성이 중요하며, 생태공원으로의 접근편리성과 안내시설 등과 같은 기본적인 시설 및 정보도 제공되어야함을 시사해주고 있다. The main purpose of this research is to examine planning factors which can be influential to the satisfaction of visitors with a case study of Kyungin Arabetgil Dumulmeori waterfront eco-park. Waterfront ecological park is a new type of park where waterfront area and ecopark are combined. There are many planning factors that would cause multicollinearity. So the research method was selected PLS regression analysis instead of typical multiple regression analysis. According to the result, the most influential factor in the satisfaction of the service users of the waterfront eco-park is community spaces which visitors are able to communicate each other (VIP rate: 1.242). Other important influential variables are as follows: easy to access (1.138), natural integrity condition as an ecological wetland (1.108), various waterfronts (1.051), guide facilities and information boards (1.036), good inhabiting environment for animals and plantsㆍecosystem protection (1.025) regeneration and restoration of the damaged ecosystem (1.016), accessibility between ecological spaces (1.007). Therefore, it is essential to apply ecological planning factors for improving satisfaction of visitors. It is also important to create some spaces to raising community awareness and park users interaction. Moreover those results suggest that it has to provide well presented basic facilities with easy accessibility and good guide information.

Cerebroplacental Ratio to Predict Adverse Perinatal Outcomes in Small-for-Gestational- Age Pregnancies

( Jaeyoung Park ),( Minji Ko ),( Byung Soo Kang ),( Jihyun Park ),( Hyun Sun Ko ),( In Yang Park ) 대한주산의학회 2020 Perinatology Vol.31 No.1

Objective: To evaluate the cerebroplacental ratio (CPR) to predict adverse perinatal outcomes in small-for-gestational-age (SGA) pregnancies. Methods: The study was a retrospective study of cases of pregnant women with SGA babies delivered between 32 and 41 weeks’ gestation, in Seoul St. Mary’s Hospital between January 2009 and December 2015. We analyzed the neonatal adverse outcomes and the risk of emergency cesarean section due to non-reassuring fetal heart rate in pregnancies with norrnal CPR and abnormal CPR in Doppler ultrasonography. Results: The abnormal CPR in SGA pregnancies was significantly associated with neonatal intensive care unit admission (P=0.042) and neonatal seizure (P=0.042), in multivariate logistic regression analysis. In receiver operating characteristic curves, the area under the curve (AUC) of abnormal CPR and severe SGA (less than 5th percentile) was 0.59, with sensitivity of 28.4% and specificity of 90.6% (P=0.038), in the emergency cesarean section due to non-reassuring fetal heart rate. However, between 32-36 weeks’ gestation, AUC of abnormal CPR was 0.7 with sensitivity of 70.6% and specificity of 69.2% (P=0.019) and AUC of abnormal CPR and severe SGA was 0.77, with sensitivity of 64.7% and specificity of 84.6% (P=0.001), in the emergency cesarean section due to non-reassuring fetal heart rate. Conclusion: When SGA is expected after 32 weeks’ gestation, measurement of CPR might be useful in predicting neonatal adverse outcome. Abnormal CPR was highly predictive of cesarean section due to non-reassuring fetal heart rate, in severe SGA, between 32-36 weeks’ gestation.

Correlation between the Korean pork grade system and the amount of pork primal cut estimated with AutoFom III

( Yunhwan Park ),( Eunyoung Ko ),( Kwangwook Park ),( Changhyun Woo ),( Jaeyoung Kim ),( Sanghun Lee ),( Sanghun Park ),( Yun-a Kim ),( Gyutae Park ),( Jungseok Choi ) 한국축산학회 2022 한국축산학회지 Vol.64 No.1

It is impossible to know the amount of pork primal cut by pig carcass grade which is determined only by carcass weight and backfat thickness in the Korean Pig Carcass System. The aim of this study was to investigate the correlation between the pig carcass grade and the amount of pork primal cut estimated with AutoFom III. A total of 419,321 Landrace, Yorkshire, and Duroc (LYD) pigs were graded with the Korean Pig Carcass Grade System. Amounts of belly, neck, loin, tenderloin, spare ribs, shoulder, and ham were estimated with AutoFom III. Regression equations for seven primal cuts according to each grade were derived. There were significant differences among the three carcass grades due to heteroscedasticity variance (p < 0.0001). Three regression equations were derived from AutoFom III estimation of primal cuts according to carcass grades. The coefficient of determination of the regression equation was 0.941 for grade 1⁺, 0.982 for grade 1, and 0.993 for grade 2. Regression equations obtained from this study are suitable for AutoFom III software, a useful tool for the analysis of each pig carcass grade in the Korean Pig Carcass Grade System. The high reliability of predicting the amount of primal cut with AutoFom III is advantageous for the management of slaughterhouses to optimize their product sorting in Korea.

Prevention and management of viral hepatitis in inflammatory bowel disease: a clinical practice guideline by the Korean Association for the Study of Intestinal Diseases

( Soo-kyung Park ),( Chang Hwan Choi ),( Jaeyoung Chun ),( Heeyoung Lee ),( Eun Sun Kim ),( Jae Jun Park ),( Chan Hyuk Park ),( Bo-in Lee ),( Yunho Jung ),( Dong-il Park ),( Do Young Kim ),( Hana Park 대한장연구학회 2020 Intestinal Research Vol.18 No.1

The treatment of inflammatory bowel disease (IBD) has been revolutionized for the last 10 years by the increasing use of immunomodulators and biologics. With immunosuppression of this kind, opportunistic infection is an important safety concern for patients with IBD. In particular, viral hepatitis is determined by the interaction between the virus and the host’s immunity, and the risk of reactivation increases if immunity is compromised by immunosuppression therapy. Parts of Asia, including Korea, still show intermediate endemicity for the hepatitis A virus and hepatitis B virus compared with the United States and Western Europe. Thus, members of IBD research group of the Korean Association for the Study of Intestinal Diseases have produced a guideline on the prevention and management of viral hepatitis in IBD. (Intest Res 2020;18:18-33)

Synthesis and characterization of pentathiophene based copolymer for organic thin film transistor.

Park, Jonggwang,Ju, Jin-Uk,Kim, Ran,Hwang, Jaeyoung,Park, Jong-Man,Kim, Yun-Hi American Scientific Publishers 2014 Journal of nanoscience and nanotechnology Vol.14 No.8

<P>The new dialkylated pentathiophene based copolymer was synthesized by Suzuki coupling reaction. The PD5TADF is synthesized and used as an active material for organic thin film transistor (OTFTs). The copolymer has good solubility in common organic solvent such as toluene, tetrahydrofuran (THF), chloroform, chlorobenzene and dichlorobenzene. The number average molecular weight (M-n) was measured to be 148,000. The TGA curve shows that the polymers exhibit good thermal stability with a weight loss of less than 5% upon heating to 419 degrees C with glass temperature at 184.9 degrees C. The ultraviolet (UV) maximum of the polymer was found at 494 nm in solution and 498 nm in the film. A thin-film transistor with PD5TADF was found to exhibit typical p-channel FET characteristics with a hole mobility of 2 x 6x10(-4) cm(2)/Vs and an on/off ratio of 3.04 x 10(4) with a threshold voltage of -4.5 V.</P>

Cyber infrastructure for <i>Fusarium</i> : three integrated platforms supporting strain identification, phylogenetics, comparative genomics and knowledge sharing

Park, Bongsoo,Park, Jongsun,Cheong, Kyeong-Chae,Choi, Jaeyoung,Jung, Kyongyong,Kim, Donghan,Lee, Yong-Hwan,Ward, Todd J.,O'Donnell, Kerry,Geiser, David M.,Kang, Seogchan Oxford University Press 2011 Nucleic acids research Vol.39 No.1

<P>The fungal genus <I>Fusarium</I> includes many plant and/or animal pathogenic species and produces diverse toxins. Although accurate species identification is critical for managing such threats, it is difficult to identify <I>Fusarium</I> morphologically. Fortunately, extensive molecular phylogenetic studies, founded on well-preserved culture collections, have established a robust foundation for <I>Fusarium</I> classification. Genomes of four <I>Fusarium</I> species have been published with more being currently sequenced. The Cyber infrastructure for <I>Fusarium</I> (CiF; http://www.fusariumdb.org/) was built to support archiving and utilization of rapidly increasing data and knowledge and consists of Fusarium-ID, Fusarium Comparative Genomics Platform (FCGP) and Fusarium Community Platform (FCP). The Fusarium-ID archives phylogenetic marker sequences from most known species along with information associated with characterized isolates and supports strain identification and phylogenetic analyses. The FCGP currently archives five genomes from four species. Besides supporting genome browsing and analysis, the FCGP presents computed characteristics of multiple gene families and functional groups. The Cart/Favorite function allows users to collect sequences from Fusarium-ID and the FCGP and analyze them later using multiple tools without requiring repeated copying-and-pasting of sequences. The FCP is designed to serve as an online community forum for sharing and preserving accumulated experience and knowledge to support future research and education.</P>

Radical Polymerization of Vinyl Monomers to Poly(vinyl)s having nBu3Sn end Groups with Biological Activity

Jaeyoung Park, Beomgi Lee, Seongsim Kim, Hyeonsook Cheong, Gyeongja Gwak, Ki Bok Lee, Hee-Gweon Woo 조선대학교 기초과학연구원 2013 조선자연과학논문집 Vol.6 No.2

Bu3Sn-endded poly(vinyl)s with biological activity were obtained by the radical polymerization of vinyl monomers using thianthrene cation radical/nBu3H. Thianthrene cation and stannyl radicals promoted the homopolymerization and copolymerization of styrene and ethyl vinyl ether having number average molecular weights of 2000- 3100. Tributyltin hydride functions as a chain transfer agent. Such polymereization by cationic thianthrene and stannyl radicals could provide some clues for the biological reaction in living animals. Plausible polymerization mechanisms were suggested.

Probing Cell-Surface Carbohydrate Binding Proteins with Dual-Modal Glycan-Conjugated Nanoparticles

Park, Sungjin,Kim, Gun-Hee,Park, Seong-Hyun,Pai, Jaeyoung,Rathwell, Dominea,Park, Jin-Yeon,Kang, Young-Sun,Shin, Injae American Chemical Society 2015 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.137 No.18

<P>Dual-modal fluorescent magnetic glyconanoparticles have been prepared and shown to be powerful in probing lectins displayed on pathogenic and mammalian cell surfaces. Blood group H1- and Le<SUP>b</SUP>-conjugated nanoparticles were found to bind to BabA displaying <I>Helicobacter pylori</I>, and Le<SUP>a</SUP>- and Le<SUP>b</SUP>-modified nanoparticles are both recognized by and internalized into DC-SIGN and SIGN-R1 expressing mammalian cells via lectin-mediated endocytosis. In addition, glyconanoparticles block adhesion of <I>H. pylori</I> to mammalian cells, suggesting that they can serve as inhibitors of infection of host cells by this pathogen. It has been also shown that owing to their magnetic properties, glyconanoparticles are useful tools to enrich lectin expressing cells. The combined results indicate that dual-modal glyconanoparticles are biocompatible and that they can be employed in lectin-associated biological studies and biomedical applications.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/2015/jacsat.2015.137.issue-18/jacs.5b00592/production/images/medium/ja-2015-00592c_0010.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ja5b00592'>ACS Electronic Supporting Info</A></P>

Global Expression Profiling of Transcription Factor Genes Provides New Insights into Pathogenicity and Stress Responses in the Rice Blast Fungus

Park, Sook-Young,Choi, Jaeyoung,Lim, Se-Eun,Lee, Gir-Won,Park, Jongsun,Kim, Yang,Kong, Sunghyung,Kim, Se Ryun,Rho, Hee-Sool,Jeon, Junhyun,Chi, Myung-Hwan,Kim, Soonok,Khang, Chang Hyun,Kang, Seogchan,L Public Library of Science 2013 PLoS pathogens Vol.9 No.6

<▼1><P>Because most efforts to understand the molecular mechanisms underpinning fungal pathogenicity have focused on studying the function and role of individual genes, relatively little is known about how transcriptional machineries globally regulate and coordinate the expression of a large group of genes involved in pathogenesis. Using quantitative real-time PCR, we analyzed the expression patterns of 206 transcription factor (TF) genes in the rice blast fungus <I>Magnaporthe oryzae</I> under 32 conditions, including multiple infection-related developmental stages and various abiotic stresses. The resulting data, which are publicly available via an online platform, provided new insights into how these TFs are regulated and potentially work together to control cellular responses to a diverse array of stimuli. High degrees of differential TF expression were observed under the conditions tested. More than 50% of the 206 TF genes were up-regulated during conidiation and/or in conidia. Mutations in ten conidiation-specific TF genes caused defects in conidiation. Expression patterns <I>in planta</I> were similar to those under oxidative stress conditions. Mutants of <I>in planta</I> inducible genes not only exhibited sensitive to oxidative stress but also failed to infect rice. These experimental validations clearly demonstrated the value of TF expression patterns in predicting the function of individual TF genes. The regulatory network of TF genes revealed by this study provides a solid foundation for elucidating how <I>M. oryzae</I> regulates its pathogenesis, development, and stress responses.</P></▼1><▼2><P><B>Author Summary</B></P><P>Rice blast disease, caused by <I>Magnaporthe oryzae</I>, destroys rice crop enough to feed 60 million people every year and has served as a model pathosystem for understanding host-parasite interactions. However, little is known about how <I>M. oryzae</I> globally regulates and coordinates its gene expression at the whole-genome scale. We analyzed the expression patterns of 206 <I>M. oryzae</I> genes encoding transcription factors (TFs) under 32 conditions, including infection-related developmental stages and various abiotic stresses, using quantitative real-time PCR. We focused on identifying the TF genes that are induced during the two most important infection-related morphogenetic changes; conidiation and infectious growth in rice. We identified 57 conidiation-specific TF genes and functionally characterized ten of them. Our data also showed that infectious growth <I>in planta</I> and oxidative stress responses <I>in vitro</I> involve largely overlapping groups of TFs. Comprehensive TF expression data and functional validation provided new insights into the regulatory mechanism underpinning pathogenicity and stress responses in <I>M. oryzae</I>. These data will also serve as a guide in studying the role of individual TF genes and the coordination of their expression in controlling development, pathogenicity, and abiotic stress responses in <I>M. oryzae</I>.</P></▼2>

Isolation and characterization of dehydroabietic acid and communic acid from Pinus densiflora needles and antihypertensive effect of Pinus densiflora needles on spontaneously hypertensive rats

Jaeyoung Park,Woong Kim,Beomgi Lee,Dong Hee Lee,Hyeonsook Cheong 한국식품영양과학회 2016 한국식품영양과학회 학술대회발표집 Vol.2016 No.10