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      • 서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

        김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

        In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

      • 내시경적 점막절제술로 치험한 식도 과립상 세포종 1례

        강혁주,김성욱,최석진,이중현,장재식,서영범,윤병구,박건욱,김성자,김용섭,강승완,이구,양창헌,이창우,김욱년,이광헌,서정일 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-

        과립상 세포종은 Schwann 세포 기원으로 생각되며 인체에 비교적 드물게 발생한다. 과립상 세포종은 전신 어느 곳에서나 발견될 수 있으나 주로 혀, 구강, 피부 혹은 유방 등에서 호발하며 드물게 위장관에서 발견된다. 위장관에서는 식도에서 가장 호발하며 다음으로 위, 대장 순이다. 과립상 세포종은 대부분, 특히 위장관에서는 양성이며 소수의 악성 병변이 보고되었다. 이러한 이유와 함께 수술 전의 진단이 어렵기 때문에 과립상 세포종에 대한 근본적인 치료는 현재까지 외과적 절제술이다. 최근에 시도되는 치료방법들로는 내시경적 레이저 치료, 용종절제술, 내시경적 점막 절제술 등이 있다. 저자들은 상부 소화관 내시경검사를 시행하여 식도 과립상 세포종을 진단하고 내시경적 점막 절제술을 시행하여 합병증 없이 퇴원하여 현재 재발없이 경과 관찰중인 1례를 경험하였기에 보고하는 바이다. Granular cell tumors, which occur infrequently, are probably of Schwann cell origin. They can occur almost anywhere in the body but usually affect the tongue, oral cavity, skin, or breasts and are rarely found in the gastrointestinal tracts. The esophagus is the most frequent gastrointestinal site, followed by the stomach and the colon. Granular cell tumors are generally benign, especially in the gastrointestinal tract, some malignant lesions have been reported. For this reason, and also because preoperative diagnosis is difficult, the standard treatment for granular cell tumor has until now been surgical excision. In recent years, other therapeutic methods is endoscopic laser therapy (ELT), polypectiomy, endoscopic mucosal resection (EMR). We report a case of esophageal granular cell tumor which was diagnosed by an endoscopy and managed using an endoscopic mucosal resection without complication.

      • 종합병원 병동형 호스피스의 공간구성에 관한 연구 : 통증완화 환경을 고려한 공간구성 계획을 중심으로 focused on spatial composition for environment mitigatied pain

        강성창,박재승 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(계획계)

        The purpose of this study presents basic data for improvement and elevation of general hospital hospice ward. With drawing investigation, interview, observation investigation etc, examine present condition of general hospital hospice ward. And, through each equipment comparison, examine confrontation construction enemy who is preceded according to hospice ward.

      • Zn를 첨가한 고온초전도체 Y Pr Ba₂Cu₃O 의 Raman 분석

        강재필,김성재,박현진,노태호,송승기,박영민,전인 明知大學校 自然科學硏究所 1997 자연과학논문집 Vol.15 No.-

        고온초전도제 Y Pr Ba₂Cu₃O 에 Zn를 첨가(x=0.00, 0.05, 0.10, 0.15, 0.20)하여 전이온도 측정, X-ray회절 실험과 Raman 실험을 하였다. Raman 측정결과 다섯 개의 시료가 일반적인 YBCO 초천도체의 Raman 스펙트럼에서 존재하는 다섯 개의 대칭활성모드(115cm¹,150cm¹.340cm¹,440cm¹,504cm¹)가 관측되었다. 이것은 Cu 와 관련된 대칭활성모드의 주파수가 모두 저주파 변위를 나타내어 Zn가 Cu(1)과 Cu(2)에 치환되었음을 의미한다. 저주파 변위 정도는 Zn에 거의 무관했으나, Raman 스펙트럼의 각 피이크의 선폭은 치환된 Zn에 의해 증가했다. 이 결과는 Zn가 Cu자리에 어느 한계 이상은 치환되지 못하고 시료 내에서 불순물상을 형성함을 나타내는 것이다. We measured transition temperature, X-ray diffraction pattern and Raman spectra of Zn added(x=0.00, 0.05, 0.10, 0.15, 0.20) high-T superconductor Y Pr Ba₂Cu₃O All samples have been observed five symmetric activity modes(115cm,150cm¹.340cm¹,440cm¹,504cm¹)which exist in Raman spectrum of general YBCO superconductor. This means Zn is substituted for Cu(1) and Cu(2) due to the fact that symmetric activity mode frequency related with Cu shows low-frequency shift. The degree of low-frequency shift was nearly independent on Zn but line width of Raman spectra peaks were increased by the substituted Zn. This results shows that Zn does not be substituted for Cu-site more than limit value and formes impurity phase in the sample.

      • FIB 신뢰성 평가를 위한 나노패턴의 설계 및 측정

        강현욱,이승재,조동우 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

        FIB (Focused ion beam) system is one of the most important equipments for the nano-scale machining. Various researches have been performed, since it can etch the material and deposit 3-D structure with high-aspect-ratio in the nanometer scale. In spite of those researches, the definite method for the reliability of FIB system has not been reported. In this paper, we proposed the reliability assessment method through nano-pattern fabrication. In the fabricated nano-pattern, the characteristics of FIB system are included. Using this effect, we tried to assess the FIB reliability. First, we suggested reliability assessment items and nano-patterns. And, to know the suitableness of the proposed method, we fabricated several nano-patterns using Nova200(FEI Company) and SMI2050(SEIKO) which are FIB apparatuses. The fabricated nano-patterns are measured with SEM (Scanning Electron Microscope) and compared with designed dimensions. And the compared results showed that the proposed method is suitable for the assessment of FIB system reliability.

      • 해수유통시설에 따른 대흑산도항 오염확산양상 변화

        강주환,문승록,박선중,정재웅 국립7개대학공동논문집간행위원회 2004 공업기술연구 Vol.4 No.-

        This study was performed to predict some aspects of tidal currents and pollutant dispersion according to the facilities for seawater exchange in order to improve the water quality in Daeheuksando. A numerical simulation was executed, using the hydrodynamic module and advection dispersion module in MIKE 21 program. As a result of hydrodynamic simulation, it did not show change greatly in all cases. But, cutting part of Jungang-breakwater increased greatly than other area. When cut inside part in Jungang-breakwater, pollutant density of Yeri area decreased greatly by the ratio of 0.40 as compared with other cases. Also, dispersion extent diffused whole area of inside sea area of Daeheuksando. This case is the most effective for seawater exchange inside sea area of Jungang-breakwater.

      • SCIESCOPUSKCI등재
      • KCI등재

        한우, 칡소 및 제주 흑우 Calpain-Calpastatin 유전자 다양성

        이승환,김승창,조수현,최봉환,Aditi Sharma,임다정,당창권,장선식,김재환,고문석,양보석,강희설 충남대학교 농업과학연구소 2013 농업과학연구 Vol.40 No.2

        The aim of study was to investigate genetic diversity for the calpain/calpastatin gene in three Hanwoo breeds [(Brown (n=62), Brindle (n=81) and Jeju Black (n=30)]. Random samples from three breeds of Hanwoo were selected and genotyped for the 7 SNPs of calpain/calpastatin using TaqMan method. Allele frequencies were investigated for CAPN1/CAST gene. Allele frequency of CAST2 SNP was 0.75, 0.59 and 0.22 for Brown, Brindle and Jeju black, respectively. The CAST3 revealed allele frequency of 0.59 and 0.57 in Brown and Jeju Black, while it showed very low allele frequency (0.07) in Brindle. In particular, favorable allele (G allele) for the CAPN1-2 SNP which was shown a strong association with tenderness in Taurine and Indicine cattle revealed 16% and 17% higher allele frequency in Brown Hanwoo (0.82) comparing Brindle (0.66) and Jeju Black Hanwoo (0.65). AMOVA demonstrated that among population variance occupied only 10% of total variance and among individual variance was 0%, while within individual variance was 90% of total variance. This result showed that population effect contributed very small portion of genetic to these three Hanwoo breeds, while within individual variance contributed large portion of genetic diversity within these Hanwoo breeds. In conclusion, three Hanwoo breeds (Brown, Brindle and Jeju black) showed a genetically homogeneous based on the 7 SNPs of CAPN1/CAST gene and it came from same ancestor to form modern Hanwoo breed.

      • KCI등재

        액체-고체 순환유동층에서 액상의 반경 방향 혼합 및 액체-고체 Chaotic 흐름 거동

        강석환,이찬기,송평섭,강용,김상돈,김승재 한국화학공학회 2004 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.42 No.2

        직경이 0.102m이고 높이가 3.5m인 액체-고체 순환유동층의 상승관에서 압력요동 및 액체의 반경 방향 혼합 특성을 고찰하였다. 상승관에서 얻은 압력요동을 해석하기 위하여 chaos 이론을 도입하였다. 액체 유속, 유동입자의 크기 그리고 고체 유동입자의 순환속도가 연속액상의 반경방향 분산계수 및 압력요동의 위상공간투영과 상관차원에 미치는 영향을 결정하였다. 본 연구의 결과 액상의 반경방향 분산계수는 유동입자의 크기와 순환속도가 증가함에 따라 증가하였으며 액상의 유속이 증가함에 따라 감소하였다. 상승관에서 압력요동의 위상공간투영은 유동입자의 크기가 고체 유동입자의 순환속도가 증가함에 따라 점점 분산되고 복잡하게 되었으나, 액체유속이 증가함에 따라서는 위상공간에서 궤적의 분산이 다소 감소하는 경향을 나타내었다. 압력요동의 상관차원은 유동입자의 크기와 고체 순환속도가 증가함에 따라 증가하였으나, 액체의 유속이 증가함에 따라서는 큰 변화가 없었다. 본 연구의 결과는, 상승관에서 액상의 반경 방향 혼합 특성 압력요동 측정함으로써 실시간으로 예측하는 것을 가능하게 하여 실제공정에 응용함으로써 그 실용적 측면이 크다고 하겠다. Characteristics of pressure fluctuations and liquid dispersion in the radial direction were investigated in the riser of a liquid-solid circulating fluidized bed whose diameter was 0.102m and 3.5m in height. The concept of chaos theory was employed to analyze the pressure fluctuations obtained in the riser. Effects of liquid velocity, particle size, and solid circulation rate on the liquid radial dispersion coefficient and phase space portraits and correlation dimension of pressure fluctuations were determined. It was found that the radial dispersion coefficient of liquid phase increased with increasing particle size or solid circulation rate, but decreased with increasing liquid velocity. The attractor in the phase space portraits became more scattered and complicated with increasing particle size or solid circulation rate, but it became somewhat less scattered with increasing liquid velocity. The correlation dimension of pressure fluctuations increased with increasing particle size or solid circulation rate, but it did not change considerably with increasing liquid velocity. The results of this study enable us to predict the characteristics of liquid radial dispersion by means of the pressure fluctuations for the practical applications.

      • 77K와 상온에서 CO(NH₂)₂의 ¹⁴N Pulsed NQR 연구

        강재필,박영민,전인,김성재,최숙자,박현진,송승기,서용문 명지대학교 자연과학연구소 1996 자연과학논문집 Vol.13 No.-

        77K와 상온에서 CO(NH₂)₂분말 시료의 ??N Pulsed NQR실험을 하여 위와 아래 공명 진동수, 핵 사중극 결합상수, 비대칭 인자, 스핀-스핀 완화시간, 결정 격자 진동에서의 평균 비틀림 진동수, 진동자의 관성 모먼트 등을 구하였다. 공명 진동수의 온도 의존성은 전형적인 Bayer이론의 격자 진동에 의한 주파수 변화를 보였다. Bayer-Kushida이론의 고온근사식을 실험값에 적용하여 OK에서 공명 진동수 ν??와 ν??를 구했으며, 77K와 상온에서의 스핀-스핀 완화시간 T₂를 관측했다. 상온에서 T₂의 감소는 결정 내의 reorientation motion과 관련이 있을 것으로 보인다. Upper and lower resonance frequencies, nuclear quadrupole coupling constants, asymmetry parameters, spin-spin relaxation time, average torsional frequency in the crystal lattice motion and moment of inertia in the oscillator are found for CO(NH₂)₂powder sample by using ??N Pulsed NQR(Nuclear Quadrupole Resonance) technique at 77K and room temperature. Temperature dependence of resonance frequencies showed frequency variation in agreement with the typical Bayer's theory in lattice motion. Resonance frequencies ν?? and ν?? at OK were obtained by fitting the high temperature approximation of Bayer-Kushida theory to the experimental data and spin-spin relaxation time (T₂) was observed at 77K and room temperature. Decrease of T₂at room temperature was explained by the effect of reorientational motion in the crystal lattice.

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