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      • 칼라영상 입 ·출력 시스템의 칼라보정 알고리듬에 관한 고찰

        신현덕,김일태,임재권,윤동한 國立金烏工科大學校附設生産技術硏究所 1995 産業技術開發硏究 Vol.11 No.-

        Colors reprodued by color image processing system are affected by various physical factors and environmental conditions. Therefore it is difficult to reproduce the original object color accurately. Thus color calibrations of the input and output data of color image processing system based on spectral distributions are required. We propose a color calibration algorithm by considering spectral characteristic of the chosen color reproduction system which can be applied to device independent color reproduction using characteristic vectors of surface reflectance. The method comprised of two steps. The first step is color analysis step which reproduces the original object color from the camera output using color characteristic vectors. The second step is color synthesis step which displays the original color accurately on the monitor by considering the monitor's phosphor spectra. The spectral responsivities of camera sensors and phosphor spectral characteristics of a given monitor are evaluated. Also, to evaluate color reproducing characteristic we applied the proposed color calibration algorithm by choosing Macbeth ColorChecker's twenty four color spectra as a test color set. As a result, we reconstruct the actual color very closely on monitor using the proposed color calibration algorithm.

      • 敗醬草가 癌細胞柱에 미치는 影響

        申大澈,權貞南,金瑩均,韓宗鉉,김재석,김재섭 동의대학교 한의학연구소 1997 동의한의연구 Vol.1 No.-

        The purpose of this study was to investigate effect of water extract of Patriniae Herba on the poliferation of human cancer cell-lines. The effects of Patriniae Herba on the poliferation of A43l, HeLa, MOLT-4, K562 cells, Balb/c 3T3 cells, mouse thymocytes, splenocytes and human lymphocytes were estimated by MTT colorimetric assay, The results were as follows; 1. Patriniae Herbs did not effect A43l, HeLa, MOLT-4, K562 cells. 2. The cytotoxicity of mitomycin C on MOLT-4 cells was increased by the combination of Patriniae Herba. 3. Patriniae Herba inhibited the proliferation of Balb/c 3T3 cells. 4. Patriniae Herba stimulated the proliferation of thymocytes. 5. Patriniae Herba stimulated the proliferation of splenocytes. 6. Patriniae Herba stimulated the proliferation of human lymphocytes.

      • KCI등재후보

        국내 혈액질환 환자에서 침습성 아스페르길루스증의 구제치료로서 Voriconazole의 효과와 안전성

        권재철,김시현,최수미,최재기,이동건,박선희,최정현,유진홍,신완식 대한감염학회 2010 감염과 화학요법 Vol.42 No.1

        Background: Invasive aspergillosis (IA) is associated with significant morbidity and mortality in patients with hematologic malignancies. We investigated the efficacy and safety of voriconazole (VCZ) when used as salvage therapy for IA in Korean adults with hematologic malignancies who had not responded to prior antifungal therapy. Materials and Methods: We retrospectively reviewed data, collected from January 2007 to October 2008, from patients with proven or probable cases of IA. All were probable IA cases, except for one proven case. All cases were refractory or intolerant to antifungal therapy prior to administration of VCZ. Efficacy and safety were assessed in patients treated with VCZ for more than 3 days and for more than one dose, respectively. A favorable response [complete (CR) or partial (PR)] was defined by significant improvement of all clinical symptoms, signs, and radiologic abnormalities. Results: Fifty patients who met the inclusion criteria were enrolled. There were 27 male and 23 female patients with mean age of 44.4 years (range, 15-65 years). Underlying diseases were acute leukemia (35 cases), chronic myelogenous leukemia (4 cases), myelodysplastic syndrome (3 cases), lymphoma (3 cases) and other hematologic diseases (5 cases). Twenty-two patients had received chemotherapy and 13 patients had undergone hematopoietic stem cell transplantation. The lung was the main infection site (94%) followed by the sinus (6%). Amphotericin B deoxycholate alone was the most frequent previous antifungal therapy. The mean duration of antifungal therapy prior to VCZ therapy was 13.9±8.8 days (2-44 days). The median duration of VCZ therapy was 19 days (interquartile range, 49 days). Sixteen patients (32.0%) showed favorable responses (CR:PR=8:8) at the end of VCZ therapy. The numbers of patients with stable disease, progression and death were, 6 (12%), 6 (12%) and 22 (44%) respectively. Most of those with unfavorable responses had relapsed underlying malignancies or refractory graft versus host diseases. Twelve patients developed drug-related adverse events but only one patient stopped VCZ treatment prematurely. Conclusions: VCZ demonstrated an acceptable level of toxicity in patients with hematologic malignancies but further studies are required to prove its efficacy as salvage therapy.

      • KCI등재

        몰리브덴이 첨가된 Stellite 6 합금의 마모와 부식특성

        申種喆,金在洙,李德悅,梁在雄,尹珍國,盧大虎,李種權 대한금속재료학회 2002 대한금속·재료학회지 Vol.40 No.10

        Hardfacing layers of Stellite 6 with different molybdenum content are deposited on AISI 1045-carbon steel using Plasma Transferred Arc welding(PTA) machine. The microstructures, wear and corrosion resistances of the hardfacing layer are investigated in order to clarify the effect of molybdenum in Stellite 6 alloys. The microstructural characterizations of the hardfacing layers are performed using X-ray diffraction, back scattered electron images, and scanning electron microscopy. With an increase of Mo contents, M_6C type carbide are formed instead of Cr-rich type carbides, and so this microstructural change enhanced the mechanical properties such as wear and corrosion resistance of a Mo-modified Stellite 6 alloy.

      • KCI등재

        산청군 산림지가 형성요인에 관한 연구

        권철현,이상태,신현철,최재채,정영관 경상대학교 농업생명과학연구원 2003 농업생명과학연구 Vol.37 No.1

        본 연구는 산청군 남부와 북부지역 361개소의 공시지가와 일반시가에 대하여 분석하였다. 지가 형성요인에 대하여 단계별 회귀분석을 실시하였으며, 그 결과는 다음과 같다. 남부지역에 대한 공시지가와 관련된 5변수 모형에 의한 추정식은 Y = 332.1973 +0.0099X_26 - 0.3577 X_8+ 0.0291X_24 - 2.6768X_2 - 26.1452X_3 이며, 회귀식에 대한 설명력은 90%로 높게 나타났으며, 일반시가에 대한 추정식은 Y = 1035.7976 -185.8280X_21 -3.3937X_1 + 405.6658X_19 -0.4703X_8 이며, 추정식에 대한 설명력은 92%롤 비교적 높게 나타났다. 북부지역에 대한 지가 형성요인에 의한 공시지가 추정모형은 Y = 176.7875 + 0.0205X_25 -0.1168X_8 + 0.0015X_26 -46.3447X_21 로 추정되었으며, 회귀식에 대한 설명력은 96%, 일반시가의 추정 모형은 Y = 203.0697 + 0.0430X_25 + 0.0027X_26 -28.8276X_4 -46.7856X_21 -0.0007X_23 으로 추정되었으며, 회귀식에 대한 설명력은 90%로 나타났다. 이상과 같이 접근요인은 부의 영향을, 그 외 다른 요인들은 지가에 양의 영향을 미치는 것으로 나타났다. This study was carried out to analyze the publicly announced land price and actual land price compared to the northern and southern region of 361 forest land place in Sanchung county. To decipher factors for making forest land price it used the stepwise regression analysis. And the result of analysis are followings; Y = 332.1973 +0.0099X_26 - 0.3577 X_8+ 0.0291X_24 - 2.6768X_2 - 26.1452X_3 (R^2=90%) and the estimation equation of actual price analyze the publicly announced and actual price compared to the northern and southern regions of Sanchung county of price was obtained as Y = 1035.7976 -185.8280X_21 -3.3937X_1 + 405.6658X_19 -0.4703X_8(R^2=92%). In the northern region, the estimation equation of publicly announced land price by the factors for making forest land price was obtained Y = 176.7875 + 0.0205X_25 -0.1168X_8 + 0.0015X_26 -46.3447X_21(R^2=96%) and the estimation equation of actual price was obtained as Y = 203.0697 + 0.0430X_25 + 0.0027X_26 -28.8276X_4 -46.7856X_21 -0.0007X_23(R^2=90%). In the result of the stepwise regression analysis, it was a showed negative effect of the proximity factor and the positive effect between others factor and land price.

      • 수술적으로 치료한 통증을 동반한 흉추부의 후외상성 Schmorl씨 결절 : 2례 보고 Report of Two Cases

        신병준,이재철,송화용,정석봉,권계원,조영일,김연일 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        Study Design : Two patients who had painful Schmorl's node at thoracic level from acute trauma were adopted and taken operation for its treatment Objectives : To document the effect of operation for the treatment of painful Schmorl's node at thoracic level summary of background data : Schrmorl's nodes are common spinal lesion generally believed to be asymptomatic, but in some cases there were painful symptom by Schmorl's node. This case report is to explain the effect of operative treatment for the painful Schmorl's node. Methods : Two patients were adopted who had traumatic painful Schmorl's node at thoracic level for our case report. They were treated conservative methods at first but it's effect were poor, so they were taken anterior decompression and fusion, and checked back pain symptom. Result : In all two patients, the symptom of back pain by Schmorl's nodes at thoracic level was almost subsided. conclusion : For the treatment of traumatic painful Schmorl's node, most of surgeon says that conservative treatments were treatment of choice, but operative treatments are also benefit to subsidence of back pain by Schmorl's node.

      • Pinus koraiensis와 Pinus parviflora의 樹高에 따른 氣孔數 變異에 關하여

        權五容,辛昌男,吳炅煥,方在旭 충남대학교 자연과학연구소 1980 學術硏究誌 Vol.7 No.2

        Stomata1 distribution in relation to the height of Pinus parviflora and Pinus koraiensis was studied 1. Stomata1 bands per needle of P parviflora and P koraiensis were 8.60±0.62 - 11.47±0.74, 14.07±1.03 - 16.60±0.99 and the number of stomata per band were 382.0±8.80 404.27±26.16, 1,326. 67±87.78 - 2,286.58±214.57, respectively 2. The number of stomatal band was significantly different between 3, 4m and 5, 6m in P parviflora and between 5, 6m and 7m in P. koraiensis Consequently, it is suggested that stomatal frequency gradient associated with increasing height above the ground is correlated with the greater degree of exposure to light.

      • KCI등재후보

        심상성 루프스에서 Nested-Primer Gene Amplification Assay에 의한 결핵균 DNA의 검출

        신문석,전효진,김병천,이규석,김재룡,권호준,송준영 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4

        Lupus vulgaris, which is a progressive form of postprimary tuberculosis in patients with a moderate to high degree of immunity and tuberculin sensitivity, is the most common, most serious, and most variable type of cutaneous and mucous membrane tuberculosis. Domonstration of M.tuberculosis directly or in culture in some of these eruptions can be difficult. It is essential to demonstrate the presence of M.tuberculosis in a clinical sample for a definitive diagnosis of tuberculosis. With the discovery of the polymerase chain reaction (PCR), the DNA diagnostic approach for infection has developed in a short period. With the dual purpose of definitive and rapid diagnosis of tuberculosis, this study examined the usefulness of a nested PCR for detection of M. turberculosis. Compared with a single-step PCR, the two-step PCR was able to enhance sensitivity approximately 1,000-fold on the basis of bacterial counts and DNA quantity. We concluded that two-step nested PCR appeared to be the most useful PCR protocol for early and sensitive diagnostic method detecting M.tuberculosis in acid-fast stain negative specimens.

      • IMT-2000용 수신단 One-chip MMIC의 설계 및 제작

        신상문,권태운,최재하 울산대학교 2002 공학연구논문집 Vol.33 No.1

        본 논문은 IMT-2000용 수신단 One-chip MMIC의 설계 및 제작에 관한 것이다. LNA, 이중 평형 믹서, LO 발룬, RF 발룬, 그리고 IF 증폭기를 하나의 칩에 집적시켰다. 새롭게 제안된 바이어스 회로는 공정상의 변화와 온도의 변화 등의 원인에 의한 문턱전압의 변화를 보상할 수 있다. 제작된 칩의 측정 결과는 모의실험으로 얻은 결과와 일치하지 않는다. LNA는 변환이득이 평탄하게 동작하지 않을 뿐만 아니라 발진현상도 나타났다. 문제에 대한 분석을 통해 원인을 찾았으며, 이 결과는 향후 연구에 사용하려고 한다. 믹서의 변환손실은 -14㏈, IP3는 4㏈m, 포트간 격리도는 25㏈ 이상인 특성을 나타낸다. 설계된 칩은 ETRI MESFET 0.5 ㎛공정으로 제작하였으며 칩 사이즈는 1.4㎜×1.4㎜이다 This is paper describes a design and fabrication of a one-chip receiver MMIC for IMT-2000. The LNA, double balanced mixer, LO balun, RF balun, IF amplifier and a bias circuit are integrated a chip. Each balun operates active and composed of MESFETs. The new applied bias circuit is able to compensate the variation of the threshold voltage caused by the process variation, temperature changes, and etc. The measured response of the fabricated chip doesn't correspond with the simulated performance, the LNA is not only the conversion gain doesn't operates flatly, but also even the oscillation presented. By the study of the cause about the problem, the factor was found. And the result will be deal with further study. The mixer achieves the conversion losses of -14㏈, IP3 of 4㏈m, and port to port isolation over 25㏈. The designed chip is fabricated by the ETRI MESFET 0.5㎛ process. The chip size is 1.4m×1.4m.

      • 초음파 시험법에 의한 실존 콘크리트 구조체의 압축강도 추정식에 관한 연구

        권영웅,유재은,신정식 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

        This study concerns the new strength equation of concrete by ultrasonic pulse velocity test. There are not only few estimate strength equations of concrete by nondestructive test, but also many problems to apply them because of time, cost, easiness, structural damage, reliability and so on. For this study, there performed a series of test and proposed a equation as follows ; Linear : fck = 70.57Vp - 222.9, r²=91.3% Quadratic : fck = 19.868Vp² - 76.6Vp + 48.1, r²=91.7% here, fc estimated compressive strength of concrete by MPa Vp : Ultrasonic Pulse Velocity of concrete by km/sec.

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