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Kyu-shik Jeong,정원일,Jae-yong Chung,Mi-young An,Chae-yong Jung,Gyoung-jae Lee,Jong-soo Kang,Byeong-cheol Kang,Young-heun Jee,Bruce H Williams,Young-oh Kwon,Da-hee Jeong 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2
Cirrhosis Occurring in a Young Woodchuck (Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus (WHV)Da-hee Jeong, Won-il Jeong, Jae-yong Chung, Mi-young An, Chae-yong Jung, Gyoung-jae Lee1, Jong-soo Kang1, Byeong-cheol Kang2, Young-heun Jee3, Bruce H Williams4, Young-oh Kwon5 and Kyu-shik Jeong*College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea1Shinwon Scientific Co., LTD, Research Institute, Suwon, Korea2Clinical Research Institute, Seoul National University, Seoul 110-744, Korea3College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea
채희백,이수빈,홍진수,김승우 순천향대학교 기초과학연구소 1997 순천향자연과학연구 논문집 Vol.3 No.2
Nd-Yag pulsed laser(210mJ, 6ns) was focused on polymer to make craters in an atmosphere. The size of the crater has a trend to follow the ideal estimation. Laser-firing near the focal point in air could be an energy dissipation of laser and a possible cause of the crater size reduction. Multiple plasma image and normal eruption of the plasma was also studied with photographs.
방사선 조사를 받은 두경부 병소의 재건을 위한 유리피판술
채수욱,고경석,김주봉,박상훈,한상훈,이택종,남순열,김상윤 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3
Radiation therapy is an effective cancer treatment modality as a primary treatment in early cancer and as an adjuvant treatment in advanced cancer, especially in head and neck lesions, but it also causes irreversible chronic damages to overlying normal tissues that may lead to wound complications. As well, at the microscopic level, radiation injury causes both stasis and occlusion of small vessels. Therefore, surgical reconstruction of previously-irradiated lesions in the head and neck poses a great problem. Fifth-six patients with head and neck lesions underwent 57 microsurgical reconstructions between 1990-1998. Thirteen patients were irradiated before surgery. The previous radiation dose was 30∼75.6 Gy. The free tissue transfer was successful in 52 of the 57 microsurgical reconstructions(91.2%). The success rate was 92.3%(12/13) in previously-irradiated patients and 90.9%(40/44) in nonirradiated patients. Postoperative complications, such as flap loss, fistula, and infection, developed in 4 irradiated patients and 8 nonirradiated patients. Overall complication rate was 30.8%(4/13) in previously-irradiated patients and 18.2%(8/44) in nonirradiated patients. Although the failure rate of previously-irradiated patients was higher than that of nonirradiated patients, there was no statistically significant difference between them. Thus, free tissue transfers in patients with previously-irradiated head and neck lesions are suitable for one-stage reconstruction.
채수흥,홍우정,김군순,조영석,김도희,김현진,구본정,송민호,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 2001 충남의대잡지 Vol.28 No.1
Background : In the previous stuides, we identified that the interferon-r activated sequence (GAS) in the 5-flanking region of rat ICAM-1 gene is major element for interferon-r-inducible expression of the gene in rat thyroid cells, FRTL-5. We here, investigated the role of transcriptional coactivators, CBP(CREB binding protein) and CⅡTA (class Ⅱ transactivator) in the modulation of the activity of GAS which could interacts with signal transducers and activators of transcription-1 and 3 (STAT1 and STAT3). Methods : The expression of CBP RNA and protein were quantitated in FRTL-5 after stimulation with interferon-r (IFN-r), thyroid stimulating hormone (TSH), forskolin and methimazole. Direct association of CBP with STAT were analyzed by immunoprecipitation. The transcriptional roles of CBP and CⅡTA in the regulation of GAS were assessed by the cotransfection with their expression vectors with reporters; 5-deletion constructs of rat ICAM-1 promoter or 8xGAS-luc constructs, into FRTL-5 thyroid cells. Results : The level of CBP RNA and protein were not changed by the treatment with TSH, IFN-r, forskolin and methimazole in FRTL-5, FRT and BRL liver cells. The CBP could be directly associated with STAT1. Furthermore, the overexpression of CBP significantly increases the both promoter activities; rat ICAM-1 gene promoter which has GAS element and 8xGAS-luc cassette constructs. However, the cotransfection of CⅡTA decreased the constitutive and CBP-mediated transactivation of rat ICAM-1 promoter and 8xGAS-luc cassette constructs. Conclusion : We identified that the two tanscriptional coactivators; CBP and CⅡTA has differential roles in the regulation of transcriptional activity of GAS drived promoter. CBP increases the GAS activity through the direct binding with STAT1, but CⅡTA inhibited the CBP-mediated transactivation of GAS activity.
마늘 장아찌 숙성 중 Allicin 성분 변화에 관한 연구
채수규 서울保健大學 1997 論文集 Vol.17 No.1
마늘 장아찌를 여러 가지 방법으로 담금하여 시제품을 제조한 후 숙성과정 중 마늘의 유효성분인 allicin 및 기타 이화학 성분의 변화를 조사 하여 비교 분석하였다. 생마늘에 대한 일반성분 분석 결과 마늘 100g당 수분은 65.80g이었고, 당질에 해당하는 가용성 무질소물 28.65g으로 가장 많았고, 단백질 2.65g, 지방질 1.12g이었으며, 무기질로서 Ca, P, Fe가 각각 25mg, 58mg, 1.7mg으로 비교적 많이 들어 있었다. 마늘 장아찌 숙성과정 중의 수분함량 변화는 담금 방법에 따라 약간 다르나 일반적으로 간장에 담근 경우에는 담금 초기 64.47%이던 것이 담금 기간이 경과할수록 감소되어 4주째는 수분 함량이 53.05%로 되었으며, 식초에 담근 경우에는 담금 초기 1주일째는 63.76%로 약간 감소하다가 4주일째는 74.25%로 다시 증가하는 추세였다. 마늘 장아찌 숙성과정 중의 염분함량 변화는 담금 방법에 따라 약간 다르나 일반적으로 식초에 담근 경우에는 0.09~0.1%로 거의 변화가 없었으나 간장에 담근 경우에는 담금 기간이 경과할수록 마늘 중의 염분함량은 0.74%로 증가되었고 액즙의 염농도는 간장 자체의 염농도 16.2%이던 것에 비해 다소 감소되어 10.6%를 나타내었다. 마늘 장아찌 숙성과정 중의 pH의 변화는 생마늘 즙액의 pH는 6.88이었으나 간장에 담근경우에는 pH 7.51의 약 알칼리성을 띠었으며, 식초에 담근 경우에는 pH4.53으로 식초에 함유된 초산에 의해 pH가 내려갔다. 마늘 장아찌 숙성과정 중의 pyruvic acid의 함량변화는 담금 방법에 따라 많은 차이를 나타내었다. 생마늘의 pyruvic acid 함량은 57.35㎍/g 이었으나 일반적으로 담금 기간 2주일째에 간장에 담근 경우에는 199.94㎍/g, 식초에 담근 경우에는 246.68㎍/g으로 각각 최고값을 나타내었다가 숙성기간이 경과할수록 감소하였다. 마늘 장아찌 숙성 과정 중의 allicin 및 diallyl disulfide의 함량변화는 일반적으로 담금 기간이 경과할수록 allicin 함량은 급격히 감소하였으며 반대로 diallyl disulfide는 크게 증가하였다. 생마늘의 allicin 함량은 23.73ppm이었으나, 간장에 담근 경우에 담금 1주일이 경과되었을 때 allicin 함량은 20.23ppm으로 85%이상 잔존하였으며 2,3,4주일이 경과되었을 때 각각 5.16ppm, 4.24ppm, 3.11ppm으로 급격히 감소하였다. 그러나 diallyl disulfide 함량은 담금 1, 2, 3, 4주일이 경과됨에 따라 각각 1.78ppm, 2.90ppm, 4.13ppm, 5.07ppm으로 약 20배정도 증가하였다. 한편 식초에 담근 경우에는 담금 1주일이 경과되었을 때 allicin 함량은 5.86ppm으로 급격히 감소하여 25% 정도만이 잔존하였고, diallyl disulfide는 담금 1주일 경과되었을 때 0.35ppm으로 약간 증가되었으나 담금 2, 3, 4주일 경과함에 따라 각각 1.82ppm, 2.57ppm, 3.12ppm으로 크게 증가하였다. Changes in the contents of allicin and the other components on the aging of pickled garlic samples prepared by the several methods were investigated. The contents of moisture, N-free extract, crude protein and crude fat were 65.80%, 28.65%, 2.65% and 1.12%, respectively, in raw garlic. Moisture content in the garlic pickled with soysauce was 64.47% at early stage of pickling and the content was decreased to 53.05% by 4th week of pickling. On the other hand, moisture content in the garlic pickled with vinegar was decreased slightly to 63.76% by 1st week of pickling, but the content was increased to 74.25% by 4th week of pickling. Salt content in the garlic pickled with vinegar was 0.09% to 0.1% and the content was not changed during the aging period. On the other hand, salt content in the garlic pickled with say sauce that salt concentration was 16.2% was increased to 0.74% and salt concentration of the juice was decreased to 10.6%. pH value in raw garlic juice was 6.88. The garlic pickled with soysauce showed alkaline pH 7.51. However, pH in the garlic pickled with vinegar was decreased to 4.53 caused by the acetic acid in vinegar. Pyruvic acid content in raw garlic was 57.35㎍/g. After 2 weeks of pickling, the contents of pyruvic acid were 199.94㎍/g in the garlic pickled with soysauce and 246.68㎍/g in the garlic pickled with vinegar. Thereafter the contents were decreased with the progress of aging. Allicin content in raw garlic was 23.73ppm. The content in the garlic pickled with soysauce was 20.23ppm with 85% remaining by 1st week of pickling. after 2, 3, and 4weeks, however, the amount of allicin was reduced to 5.16ppm, 4.24ppm and 3.11ppm, respectively. Diallyl disulfide content in the garlic pickled with soysauce was increased remarkably to 5.07ppm by 4th week of pickling. On the other hand, allicin content in the garlic pickled with vinegar was 5.86ppm with 25% remaining by 1st week of pickling and diallyl disulfide content in the garlic pickled with vinegar was increased to 3.12ppm by 4th week of pickling.
蔡洙天 公州大學校 資源科學硏究所 1998 資源科學硏究論文集 Vol.6 No.-
Dry weight and percentage of dry matter increased after the occurrence of flag leaf. In this case, free sugar contents were the greatest in September when flag leaf occurred and slowly decreased afterSeptember while nob-free sugar increased vice versa. According to the analyses of fatty acids in Dendrobium stem, linoleic acid was the highest whereas myristic acid wasthe least. Content of pentadecanoic acid increased continuously after occurrence of flag leaf but content of oleic acid was high on September when flag leaf occurred and then decreased gradually, speculating that it may have something to do with flower bud formation.
채수환 한국항공대학교 1989 論文集 Vol.27 No.-
병렬처리형 계산시스템에서의 선형 방정식 시스템의 해를 구하기 위한 두개의 직접 방법인 Gauss 제거법과 Gauss - Jordan법을 비교 논의하였다. 특히 병렬성과 병렬 수행기간에 대해서 주로 고찰되었다. Two direct methods, Gauss elimination method and Gauss-Jordan method are discussed about parallelism and parallel execution time to solve systems of linear equations with parallel processing computing systems.