Selenium 공급방법이 수경재배 토마토의 생장과 Se 흡수에 미치는 영향

이철규(Cheol-Kyu Lee),조경철(Kyung-Cheol Cho),이정현(Jeong-Hyun Lee),조자용(Ja-Yong Cho),서범석(Beom-Seok Seo),양원모(Won-Mo Yang) (사)한국생물환경조절학회 2005 생물환경조절학회지 Vol.14 No.4

토마토 ‘모모타로’를 공시하여 셀레늄 10㎎ㆍL?¹의 관주 및 엽면시비 등의 단용 및 혼용처리가 수경재배 토마토의 생육 및 과실 내 셀레늄 축적 함량에 미치는 영향을 구명하였다. 토마토 종자를 50공 트레이에 파종하여 70일 동안 육묘한 후 유묘를 코코피트 슬라이브를 이용한 수경재배 시스템에 정식하였다. 양액은 일본원예시험장 배양액 표준처방으로 조성하였으며, pH 5.8~6.2와 EC 2.3 ㎎ㆍL?¹ 등으로 조절하여 공급하였다. 셀레늄은 무기태 SeO₂와 sugar fatty acid ester에 킬레이트화 한 유기태 셀레늄을 10 ㎎ㆍL?¹으로 조성하여 관주, 엽면시비, 관주와 엽면시비를 병행하여 처리하였다. 초장, 엽수, 엽면적 및 엽록소 등의 토마토 생장반응은 셀레늄의 엽면시비, 그리고 엽면시비와 관주를 병행한 처리구에서 현저히 증가하였다. 과실 내 셀레늄 축적 함량은 킬레이트화 한 유기태 셀레늄을 엽면시비와 관주를 병행하여 처리한 경우에 0.302 ㎎ㆍL?¹으로 가장 높았다. 무기태와 유기태 셀레늄의 엽면시비와 관주 등의 단용 처리 보다는 혼용 처리가 전반적인 과실 생장과 체내 셀레늄 축적에 효과적이었다. 무기태 설레늄(SeO₂) 보다는 sugar fatty acid ester에 킬레이트화한 유기태 셀레늄 처리가 셀레늄을 함유한 기능성 토마토의 수경재배에 더 효과적이었다. This study was conducted to clarify the effects of supplying methods of selenium on the growth and Se uptake of hydroponically grown tomato plants. Tomato seeds (Lycopersicum esculentum Mill. cv. Momotaro T-93, Daki Seed Co.) were sown in plug tray with fifty holes, and raised for sixty days. Tomato seedlings transplanted to coco fiber slabs were supplied with the nutrient solutions adjusted to EC 2.3 dSㆍm?¹ and pH 5.8~6.2 recommended by the Japanese Horticultural Experiment Station. Selenium forms used were inorganic SeO₂ (here in after referred to Se) and organic selenium chelated with sugar fatty acid ester (here in after referred to chelated-Se). 10 ppm selenium solutions were treated to tomato plants with foliar applications, drenching, and foliar application plus drenching. Growth characteristics in terms of plant height, number of leaves, leaf area and chlorophyll content were significantly increased in the plot of foliar application of Se, and in the plot of foliar application plus drenching of chelated-Se than other plots, respectively. Transported contents of selenium into the tomato fruits were highest as 0.302 ppm in the plot of foliar application plus drenching of chelated-Se. Also, it had tended to be higher in the plot of foliar application plus drenching than in the plots of foliar application or drenching in both of Se and chelated-Se. Foliar application and drenching of organic chelated-Se were effective to produce the functional tomato fruits.

서울市內一部 動物病院에서 臨床診療된 愛玩犬의 病類別 分布에 對한 醫學統計學的 考察

徐政煜,李元暢,鄭柄鉉,尹和重 건국대학교 동물자원연구센터 1999 動物資源硏究誌 Vol.20 No.-

우리 나라의 소동물 수의임상분야(獸醫臨床分野)에서 주류를 이루고 있는 애완견의 병류별 질병분포를 파약하여 수의임상반야의 기초자료로 제시하고자 시도하고 서울시내 중견 동물병원 5곳을 무작위선택방법에 의하여 선정하여 1993년도부터 1995년도 말까지 3개년간의 임상의료철을 수집, 의학통계학적 방법을 이용 분석 및 관찰한바 몇 자기 결과를 얻어 다음과 같이 적요 한다. 진료과별 진료건수의 분포를 보면, 전체진료건수 8,360건 중에서 내과질환이 53.6%를 점유하고, 외과질환은 13.01%, 비뇨생식기질환1.96%, 피부과질환 15.47%, 안과질환 2.68% 그리고 이(耳)과질환 13.28% 등으로 관찰되었다. 조사 관찰된 내과질환은 총 19종의 질병과 4,481건의 진료건수가 있었으며, 이중에서 위발증(胃發症)이 가장 많아 21.38%를 점유하고 있었고, 외과질환은 성형외과와 정형외과 질환을 포함하여 역시 총 19종의 질병과 1,088건의 진료건수가 있었는데, 이중에서 외상(外傷)이 가장 많아 19.21%, 비뇨 생식기질환은 6종류의 질병과 164건의 진료건수가 있었으며, 그 중에서 비뇨기 감염증이 가장 많아 37.0%를, 피부질환은 5종의 질병에 1,293건의 진료가 있었고, 이중에서 체외기생충의 감염이 37.74% 그리고 안이과(眼耳科)질환은 7종에 1,332건으로 외이염(外耳炎)이 가장 많아 59.49%를 점유하고 있었다. 애완견에서 빈발하는 10대 질환의 분포를 관찰하바, 위염 (11.46%), 위장염(10.28%), 외이염(9.74%), 기관기관지염(8.49%), 대장염(6.41%), 체외기생충증(5.84%), 체내기생충증(4.35%), 이내(耳內) 진드기(3.8%), 피부진균증(3.53%) 및 피지누증 (3.12%) 등의 순으로 관찰되었다. 끝으로 애완견의 전염병으로는 distemper가 44.8%, parvoviral infection 39.37%, coronaviral infection 15.83% 그리고 본조사기간중 서울시내에서의 rabies 발생건수는 전혀 없었다. The purpose of this study was to a retrospective and medical statistical observation on the clinical cases of pet-dogs by veterinary hospital in Seoul City, during the period from 1993 to 1995, which important not only in veterinary clinic but also pet animal health information system development for veterinary practitioner of Korea. The results were summarized as follows: In the clinical cases determined by the international classification of diseases, during the period of three years, 8,358 cases of morbidity of pet-dogs were shown by five veterinary hospital for small animals. Among them, the disease of internal medicine, including medicine, including digestive, respiratory, circulatory, metabolic and parasitosis were 53.6% of total cases, the surgical disease, including orthopedic and plastic surgery were 13.01%, the disease of urogenital was 1.96%, the disease of dermatology was 15.47%, the disease of ophthalmic was 2.68% and the disease of otiatric was 13.28%, respectively. The gastric crisis of 21.38% among 4,481 cases of 19 kinds on the disease of internal medicine showed the highest morbidity. The trauma of 19.21% among 1,088 cases of 19 kinds in the surgery, including orthopedic and plastic surgery, the case of urogenic infection of 37.0% among 164 cases of 6 kinds in the urogenital organe, the ectoparasitosis of 37.24% among 1,293 cases of 5 kinds in the disease of dermatology, the otitis externa of 59.49% among 1,332 cases of 7 kinds n the opthalmatic and otiatric diseases showed the highest morbidity in each part of veterinary clinics. Observation on the morbidity of the main disease of pet-dogs were gastritis (11.46%), gastroenteritis (10.28%), ectoparasitosis (9.64%) including ear-mite, otitis externa (9.47%), trachobronchitis (8.49%), enterocolitis (6.41%), endoparasitosis (4.35%), dermatophytosis (3.53%) and seborrhea (3.12%), respectively. Finally, distributive observation on the incidence case of the main infections disease in pet-dogs which that distemper, parvoviral infection and coronaviral infection were 44.80%, 39.37% and 15.83, respectively.

제통단이 퇴행성 슬관절염 환자의 삶의 질에 미치는 영향

서병관,류성룡,강중원,우현수,이상훈,이재동,최도영,김건식,이두익,이윤호 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objectives : to evaluate the effects of Jetongdan, the newly developed herbal medicine, on the quality of life in patients with osteoarthritis of knee Methods : Placebo-controlled, randomized clinical trial on the 80 patients with osteoarthritis of the knee was fulfilled. After enrollment, they took medication as they enrolled. And they were asked to answer the questionnaires (Korean Health Assessment Questionnaire (KHAQ), Lequesne's functional index (LF1), visual analogue scale (VAS)) and analysed with the erythrocyte sedimentation rate (ESR) at baseline, after 4 weeks and 8 weeks of medication. Results : Total KHAQ score, some categories of KHAQ like hygiene, activities were significantly improved after 8 weeks of medication. And the change of the KHAQ score was significantly correlated with the change of VAS. But LFI, VAS, ESR level was not significantly improved, and it was considered because of the short medication period and small size of study population. Conclusion : In conclusion, Jetongdan could improve the health-related quality of life in patients with osteoarthritis of knee. Further study in the large population, in long period were recommended.

서양산 고추냉이 추출물이 함유된 세치제의 효능에 대한 임상적 실험연구

서현우,박호원,김종수,이시영,신일식 大韓小兒齒科學會 2012 大韓小兒齒科學會誌 Vol.39 No.1

The purpose of this study was to find out the effect of dentifrice containing Horseradish (Armoracia rustica) root extracts on improvement of oral hygiene. The clinical evaluation was done participated by 80 adults volunteers who provided a informed consent for their participation. The participants were divided into two groups ; control group (using toothpaste without Horseradish extracts) and experimental group (using toothpaste containing Horseradish extracts). The checklist of the experiment includes the plaque index, gingival index and anti-caries activity. The anti-caries activity was measured by cultivating Streptococcus mutans for 48 hours then estimating the number of increased bacteria using Dentocult SM. The double-blind method was used in this study. The results of this study can be summarized as follows; 1. The plaque formation decreased 28% in control group, 58% in experimental group using dentifrice with Horseradish extracts compared to baseline data. 2. For gingival index, control group and experimental group showed 26% and 40% decrease compared to baseline data, respectively. 3. The score of caries activity test decreased by 4% for control group and 69% for experimental group compared to baseline data. According to the results, a dentifrice containing Horseradish extracts can improve oral hygiene. 식물성 자연추출물 중 하나인 고추냉이 추출물을 배합한 세치제의 구강환경 개선 효과를 알아보기위해 총72명을 대상으로 교차실험 및 이중맹검법을 실시하여 치면세균막지수, 치은염지수 및 우식활성도검사 등을 비교 검토한 결과 다음과 같은 결 론을 얻었다. 1. 치면세균막지수는 초기값에 비해 대조군은 28%, 고추냉이 추출물 배합세치군은 58%의 억제효과를 나타내었다. 2. 치은염지수는 초기값에 비해 대조군은 26%, 고추냉이 추출물 배합세치군은 40%의 억제효과를 나타내었다. 3. Dentocult-SM을 이용한 우식활성도 평가에서는 초기값에 비해 대조군은 4%, 고추냉이 추출물 배합세치군은 69%의 억제효과를 나타내어 고추냉이 추출물 배합세치군이 대조군에 비해 유의할만한 Streptococcus mutans 억제효과를 나 타내었다. 이상의 결과들로 보아 고추냉이 추출물을 배합한 세치제는 치면세균막 억제와 치은염의 감소 그리고 우식활성도 억제에 중 요한 역할을 하여 구강환경 개선에 뛰어난 효과를 보이는 것으로 사료된다.

만성경부통증 환자에 대한 근막이완술과 경피신경 전기자극 치료가 치료기간에 따라 관절가동범위와 통증에 미치는 영향

서현규,공원태,이상용 대한정형도수치료학회 2005 대한정형도수물리치료학회지 Vol.11 No.2

The purpose of this study is compare the effects of two therapeutic processes-ⅰ) conservative Myofacial Release Technique along and ⅱ) Transcutaneous Electrical Nerve stimuliation alone - on the increase in the range of motion(ROM) and on the decrease in patient's pain with chronic Neck pain. The subjects of the study were student with choronic neck pain in Daegu health university. Half of them (10) took conservative Myofacial Release Technique along and the others (10) took Transcutaneous Electrical Nerve stimuliation alone.I used 3D Motion analysis. The range of motion (ROM) in six areas-flexion, extension, left lateral flexion, right lateral flexion, left rotation, right rotation-to check the effectiveness of the two combinations of methods, measured pain with visual analogue scale (VAS) to see the effect on pain reduce. Assement was conducted to the groups before the treatment began and affer the four weeks treatment ended. This study shows that both groups demonstrated significant improvement in ROM increase and pain reduction. Flexion ROM increases were significant in MFR and TENS after treatment 2 weeks and 4 weeks. Extension ROM increases were significant in MFR and TENS after treatment 2 weeks. Right rotation ROM was no significant differences were found in MFR and TENS after treatment all weeks. Right lateral flexion ROM increases were significant in MFR and TENS after treatment 3 weeks. Left lateral flexion ROM increases were significant in MFR and TENS after treatment 1 weeks. But the others no significant differences were in MFR group and TENS group during 4 weeks.

다중 스펙트럼 화상 분류에 있어서 이진 다이아몬드 신경망과 비 파라메트릭 화소 단위 방법의 적용

元聖賢,徐元一,金鎭逸 東義大學校産業技術開發硏究所 1994 産業技術硏究誌 Vol.8 No.-

This paper deals with the application of nonparametric pixel-by-pixel classification methods in the classification of pixels, based on their multispectral data. And a new neural network, the Binary Diamond, is introduced, and its performance is compared with a nearest neighbor algorithm and a back-propagation network.

한국형 우울장애 약물치료 알고리듬 2006 (Ⅰ)

서정석,민경준,김원,석정호,박원명,송해철,이상열,전덕인,전현태,홍진표,한국형 우울장애 약물치료 알고리듬 2006 연구그룹 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.5

Objectives : Since the publication of Korean Medication Algorithm Project for Major depressive Disorder (KMAP-MD) in 2002, there has been a substantial need for a revision due to rapid progress in the pharmacological management for depressive disorder. We revised KMAP-MD to Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) in 2006. This paper is one of the following 4 papers consisting of Korean pharmacological algorithm for depressive disorder. Methods : The questionnaire consisted of 4 parts ; initial treatment of 1) non-psychotic depressive disorder, 2) psychotic depressive disorder, 3) treatment strategy for clinical subtypes and drug choice considering adverse effects, and 4) treatment for depressive disorder in women. It was composed of 22 questions, and each question had 54 sub-items. The questionnaire was completed by the review committee consisting of 101 experienced Korean psychiatrists. We classified the expert opinion to 3 categories (the first-line, the second-line, or the third-line). Results : For non-psychotic major depression, regardless ofthe severity of an episode, the antidepressant (AD) monotherapy was the optimal first-line treatment. SSRI, venlafaxine, and mirtazapine were the 1st-line AD. In case of a partial or no response to initial strategy, adding another AD was recommended. For psychotic major depression, combination of an AD and an atypical antipsychotic (AAP) was the treatment of choice. Among AAPs, quetiapine, rispendone, olanzapine were preferred. For non-responder to initial strategy, the next step was adding or changing AD before changing AAP. For women with premenstrual dysphoric syndrome or postpartum depression without psychotic features, AD monotherapty was a preferred strategy while for psychotic postpartum depression, combination of AD and AAP was recommended. Experts recommended various ADs according to adverse effect. Conclusion : These results suggest that the medication strategies for depressive disorder are rapidly changing and reflect the recent studies and clinical experiences.

광원에 따른 수종의 치면열구전색제로부터 용리되는모노머에 관한 연구

서현우,박호원 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.2

본 연구에서는 치과용 복합레진의 중합률에 영향을 미치는 다양한 장원인 할로겐, 플라즈마, LED를 사용하여 임상에서 사용하는 여러 치면열구전색제들을 중합 시, 이로부터 용리되는 미반응 모노머들을 확인하고 정량화하고자 하였다. 5가지의 광중합형 치면열구전색제를 각각의 광원에 따라 중합한 시편을 제작하여 3차 증류수에 넣은 후 바로 용리시킨 액을 0시간으로 하고 37℃ 항온수조에서 10분, 1시간, 12시간, 24시간 보관한 후 각각의 용리액을 고성능 액채 크로마토그래피를 이용하여 미반응 모노머의 정성 및 정량 분석을 시행하였고, 다음과 같은 결과를 얻었다 1. 표준 모노머들의 분리시간은 BPA 2.3분, TEGDMA 3.2분, UDMA 5.6분, Bis-GMA 6.5분, Bis-DMA 10.4분 이었다. 2. 모든 치면열구전색제에서 TEGDMA를 제외한 어떠한 모노머들도 용리되지 않았다. 3. 저장 12시간까지 대부분의 TEGDMA가 용리되었으며, 이후부터는 그 양이 현저히 줄어드는 양상을 보였다. 4. 최소권장중합 시간인 할로겐 20초, 플라즈마 3초, LED 10초 중합 시 TEGDMA의 용리량은 할로겐, LED, 플라즈마 순으로 적었다. 5. 모든 중합기에서 Pit & Fissure Sealant™의 용리량이 가장 적었으며, 할로겐 중합시 Helioseal?가 플라즈마 아크 중합 시 Concise™가, LED 중합 시 Teethmate? F-1이 가장 많은 용리량을 보였다. The aim of this study was to identify and quantify the major or detectable monomers released from any of five commercially-available, light-cured pit and fissure sealants with three different light sources : conventional halogen light curing unit, plasma arc light curing unit and LED curing unit. After curing, specimens were immediately immersed in distilled water for different time intervals. The time related release of monomers were analyzed by high performance liquid chromatography(HPLC). Identification and quantitative analysis of monomers were performed by the comparison of the elution time and the absorption peak height of the eluates with those of the authentic sample. The result of this study can be summarized as follows. 1. Standard solution peaks with retention times of 2.3, 3.2, 5.6, 6.5, 10.4 minutes were identified as BPA, TEGDMA, UDMA, Bis-GMA, Bis-DMA, respectively. 2. None of the chromatograms of the tested sealants displayed peaks with the same retention time as that of the standard solution, except for TEGDMA. 3. The highest release rate of TEGDMA was observed during the 12hr period for all samples and declined thereafter. 4. The elution of TEGDMA from curing with Halogen curing unit for 20 second and LED for 10 second was less than that resulting from curing with Plasma arc for 3 second. 5. TEGDMA was detected at much lower levels in eluates from the Pit & Fissure Sealant™ than other sealants. The elution of TEGDMA from the Helioseal? F cured with Halogen light curing unit, the Concise™ cured with Plasma arc curing unit and the Teethmate? F-1 cured with LED curing unit were higher than other sealants.

소뇌뇌교각종양에서 수술중 전기생리학적 신경계집중감시의 변화

서대원,박관,안재영,이상구,정진상,홍승봉,이원용,김병준,김종현 대한신경과학회 1999 대한신경과학회지 Vol.17 No.1

Pilomatricoma 환아에 대한 증례 보고

서현우,김지혁,박호원 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.1

Pilomatricoma(Calcifying epithelioma of Malherbe)는 모낭 세포 기원의 양성 연조직 종양으로, 보통 머리와 목 부위에 나타나며, 20세 이전의 여성들에게서 호발하고, 악성으로의 전이가 보고되기도 하나, 이는 극히 드물다. 임상적으로, 무통성, 표재성, 고형성이며 종종 적청색을 나타내고, 크기는 보통 0.5~3.Ocm 정도로 다양하게 나타난다. 조직학적으로, 세포기질 내에 상피조직이 존재하는 형태이며, 상피조직에서는 기저제포(basaloid cell)와 유령세포(ghost cell)가 특징적으로 나타나고, 세포내와 기질내 석회화가 종종 관찰되기도 한다. 진단은, 초진시 고형 물질의 촉진으로 병소를 의심해볼 수 있고, 조직병리학적 검사로 확진할 수 있다. 감별진단으로는 아가미낭(branchial cyst), 혈관종(hemangioma), 횡문근육종(rhabdomyosarcolna), 표피포함낭(epidermal inclusion cyst), 모낭(pilar cyst), 이하선 종양(parotid gland tumor), 피부의 골종(osteomas of the skin) 림프절의 석회화(calcified lymph nodes), 죽종(atheromas) 등이 있다. 치료로는 외과적 절제술이 추천되며 재발은 드물다. 본 증례는 우측 하악각 부위에 결절이 촉진되는 6세 여자 환아에게서 임상 검사와 방사선 검사 후 병소의 외과적 절제술을 시행하였으며, 조직병리학적 검사를 통해 pilomatricoma로 확진되었고, 양호한 치료 결과를 얻었기에 이에 보고하는 바이다. Pilomatricoma is a benign soft tissue tumor of hair follicle origin. They occur most commonly in the head and neck region and are usually found in girls during the first two decades of life. Although malignant transformation has been described, it is exceedingly rare. The clinical presentation is typically that of an asymptomatic, superficial, solitary, firm mass that is often accompanied by a reddish-blue discoloration of the overlying skin. Histopathologically pilomatricoma are seen as epithelial islands embedded in a cellular stroma. The epithelial component consist of two main cell types : basaloid cells and ghost cells. Intracellular and stromal calcification is reported in many cases. Diagnosis is usually suspected based on palpation of a superficial, rock-hard mass and confirmed by histopathologic examination. Surgical excision is both curative and the treatment of choice. Recurrence is rare. In this case, the radiographs showed a dense calcification, measuring about 1cm diameter. So simple excision was performed intraorally, and resultantly the lesion was proved to be a pilomatricoma by histological examination.