아동의 物活論的 思考에 관한 연구 : Piaget의 가설을 중심으로

李恩和,尹賢燮 이화여자대학교 한국문화연구원 1976 韓國文化硏究院 論叢 Vol.28 No.-

This study was intended to investigate the Korean child's animism and to test Piaget's hypothesis with Huang-Lee's experimental tools. The experimental hypotheses in this study were: 1) Piagetian animism could be found in Korean children's mentality, and 2) Piaget's hypothesis could be proved not only by Russell-Dennis's tools but also by Huang Lee's. Russell and Dennis have proved Piaget's hypothesis and standardized the experimental procedures to test child's animism; however, M. Mead and Huang-Lee have denied the Piagetian animism in Manusian and Chinese children. Russel and Dennis have also suggested four developmental stages in child's animism. Twenty Korean children, aged between 4-7, were tested individually, the combined experimental procedures of Russell-Dennis and Huang-Lee being used, As a result, the first hypothesis in this study was positively confirmed only by Russell-Dennis's method. This means that the second hypothesis in this study was not confirmed. 90% of the Subjects in this study have had the concept of life or living, and did not regard inanimate objects as having characteristics of "feeling pain." It seems to us that the subjects in this study tend to make some cognitive continuity between their awareness of their living and the being of physical objects. In Piagetian terms, the subjects have not dissociated themselves from their physical and natural environment.

A sub-1-volt nanoelectromechanical switching device.

Lee, Jeong Oen,Song, Yong-Ha,Kim, Min-Wu,Kang, Min-Ho,Oh, Jae-Sub,Yang, Hyun-Ho,Yoon, Jun-Bo Nature Pub. Group 2013 Nature nanotechnology Vol.8 No.1

<P>Nanoelectromechanical (NEM) switches have received widespread attention as promising candidates in the drive to surmount the physical limitations currently faced by complementary metal oxide semiconductor technology. The NEM switch has demonstrated superior characteristics including quasi-zero leakage behaviour, excellent density capability and operation in harsh environments. However, an unacceptably high operating voltage (4-20 V) has posed a major obstacle in the practical use of the NEM switch in low-power integrated circuits. To utilize the NEM switch widely as a core device component in ultralow power applications, the operation voltage needs to be reduced to 1 V or below. However, sub-1 V actuation has not yet been demonstrated because of fabrication difficulties and irreversible switching failure caused by surface adhesion. Here, we report the sub-1 V operation of a NEM switch through the introduction of a novel pipe clip device structure and an effective air gap fabrication technique. This achievement is primarily attributed to the incorporation of a 4-nm-thick air gap, which is the smallest reported so far for a NEM switch generated using a 'top-down' approach. Our structure and process can potentially be utilized in various nanogap-related applications, including NEM switch-based ultralow-power integrated circuits, NEM resonators, nanogap electrodes for scientific research and sensors.</P>

2,4-bis (p-hydroxyphenyl)-2-butenal (HPB242) induces apoptosis via modulating E7 expression and inhibition of PI3K/Akt pathway in SiHa human cervical cancer cells.

Kim, Man Sub,Kim, Jung Hee,Bak, Yesol,Park, Yun Sun,Lee, Dong Hun,Kang, Jeong Woo,Shim, Jung-Hyun,Jeong, Heon Sang,Hong, Jin Tae,Yoon, Do Young Lawrence Erlbaum Associates, Publishers [etc.] 2012 Nutrition and cancer Vol.64 No.8

<P>The Maillard reaction is a chemical reaction occurring between an amino acid and a reducing sugar, usually requiring thermal processing. Maillard reaction products (MRPs) have antioxidant, antimutagenic, and antibacterial effects, and although 2,4-bis (p-hydroxyphenyl)-2-butenal (HPB242), a fructose-tyrosine MRP, appears to inhibit proliferation of cancer cells, its mechanism of action has not been studied in detail. We found that HPB242 treatment modulated expression of cyclins and tumor suppressor genes in SiHa human cervical cancer cell lines: cyclins and phospho-pRB were downregulated, whereas the expression of CDK inhibitors and p53 was enhanced. HPB242 induced apoptosis dose-dependently by suppressing E7 expression and leading to sub-G1 cell-cycle arrest in SiHa cell lines; treatment also led to the proteolytic cleavage of caspase-3, -9, and poly (ADP-ribose) polymerase. Moreover, HPB242 upregulated Fas expression, altered expressions of pro- and antiapoptotic factors, and also inhibited nuclear translocation of nuclear factor κB and phosphorylation of IκB. HPB242 treatment decreased phosphatidyl inositol-3 kinase and p-Akt expression levels, demonstrating that this survival pathway may also be inhibited by HPB242. Cumulatively, HPB242 promotes apoptosis by influencing E7 expression, inducing cell-cycle arrest at sub-G1 phase, and promoting both intrinsic (mitochondrial) and extrinsic (Fas-dependent) apoptosis in SiHa human cervical cancer cells.</P>

Haplogroup Classification of Korean Cattle Breeds Based on Sequence Variations of mtDNA Control Region

Kim, Jae-Hwan,Lee, Seong-Su,Kim, Seung Chang,Choi, Seong-Bok,Kim, Su-Hyun,Lee, Chang Woo,Jung, Kyoung-Sub,Kim, Eun Sung,Choi, Young-Sun,Kim, Sung-Bok,Kim, Woo Hyun,Cho, Chang-Yeon Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.5

Many studies have reported the frequency and distribution of haplogroups among various cattle breeds for verification of their origins and genetic diversity. In this study, 318 complete sequences of the mtDNA control region from four Korean cattle breeds were used for haplogroup classification. 71 polymorphic sites and 66 haplotypes were found in these sequences. Consistent with the genetic patterns in previous reports, four haplogroups (T1, T2, T3, and T4) were identified in Korean cattle breeds. In addition, T1a, T3a, and T3b sub-haplogroups were classified. In the phylogenetic tree, each haplogroup formed an independent cluster. The frequencies of T3, T4, T1 (containing T1a), and T2 were 66%, 16%, 10%, and 8%, respectively. Especially, the T1 haplogroup contained only one haplotype and a sample. All four haplogroups were found in Chikso, Jeju black and Hanwoo. However, only the T3 and T4 haplogroups appeared in Heugu, and most Chikso populations showed a partial of four haplogroups. These results will be useful for stable conservation and efficient management of Korean cattle breeds.

손마사지가 허혈성 심질환 환자의 불안에 미치는 효과

현경선,이향련,공송심,윤경자,김현섭,김효남,최지원,김운정 성인간호학회 2001 성인간호학회지 Vol.13 No.2

The purpose of this study was to investigate the effect of a hand massage program on anxiety, vital sign and pain in clients with ischemic heart disease. The design utilized for this stuffy was quail-experimental with a nonequivalent control group non-synchronized design The subjects were fifty-four patients, twenty-eight for the experimental and twenty-six for the control group, who were admitted with ischemic heart diease at a cardiac intensive care unfit in K medical center of K university. This study was carried out from May, 1999 to March, 2000. The level of anxiety and pain measured by Visual Analogue Scale, systolic blood pressure, diastolic blood pressure and pulse rate were measured before and after hand massage, the state of Anxiety was measured by the Spielberger (1970) scale at admission and after hand massage for three days. The collected data were processed by using the SPSS PC program and analyzed using χ2-test and t-test. The result of this study are as follows : 1. The scores of VAS anxiety and State of anxiety of the experimental group were lower than those of the control group. 2. The degree of systolic blond pressure, diastolic blood pressure and pulse rate of the experimental group were lower than that of the control group. 3. The score of VAS pain of the experimental group was lower than that of the control group. The results suggested that hand massage can decrease VAS anxiety, State of anxiety, vital signs and VAS pain of patients who were admitted with ischemic heart disease at cardiac intensive care unit Therefore, It Is proposed that hand massage is an appropriate nursing intervention to relieve anxiety of the patients who were admitted with ischemic heart disease at a cardiac intensive care unit.

Die-upset Nd_(15)Fe_(77)B_8 자석의 자기적 특성에 미치는 제조조건 및 Ga 첨가의 영향

이경섭,김용성,박현순,서수정 成均館大學校 科學技術硏究所 1995 論文集 Vol.46 No.1

The effects of process parameters and Ga addition on the magnetic properties of die-upset Nd_15Fe_77B_6 magnets were studied. The intrinsic coercivity (_iH_C) was decreased because of grain coarsening by die-upset process. The Remanence (4πM_r) was varied by the extend of crystalline anisotropy. The alignment of c axis depend on the temperature and speed of die-upset process. The coercivity loss by die upsetting was reduced with Ga addition.

생쥐 대장 평활근 세포에서 내향 정류성 칼륨 전류의 특성 연구

이은주,김명,정명섭,조향훈,김기훈,하현철,김준수,최석,전제열 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Objectives: K^(+) channels play an important role in regulating cellular excitability. The aim of this study was to know whether or not inward rectifier K^(+) channel exists in colonic smooth muscle cells. Methods: Mouse colonic smooth muscle cells were isolated using collagenase, and then we recorded their membrane currents using a whole-cell patch clamp technique. Results: With 90 mM K^(+) in bath, hyperpolarization-induced inward currents from -120 mV to 20 mV with 400 ms duration at a holding potential of -10 mV showed rapid activation, inactivation and inward rectification. The inactivation showed single exponential time course. Reduction of external K^(+) to 60 mM decreased the amplitudes of the currents in whole test voltage range and shifted the reversal potential to more negative potential. The inactivation process and peak currents of hyperpolarization-induced inward currents were not affected by removing external Na^(+). External Ba^(+) blocked hyperpolarization-induced inward currents by dose-dependent manner and pure Ba^(+)-sensitive currents showed strong inward rectification. Cs^(+) also suppressed hyper- polarization-induced inward currents. Ba^(+) and Cs^(+)-induced inhibitiOn of hyperpolarization-induced inward currents was voltage-dependent, and the extent of inhibition increasing with membrane hyperpolarization. Conclusions: These results suggest that inward rectifier KU channels may exist in proximal colonic smooth muscle and may play an important role in regulating membrane potential.

요통 및 방사통 환자에서 고장성 식염수를포함한 경막외 주사 효과

김현배,김미정,최기섭,이상건 大韓再活醫學會 1999 Annals of Rehabilitation Medicine Vol.23 No.1

Green 정리를 이용한 철근 콘크리트 단주해석

이홍주,박현재,진치섭 釜山大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.53 No.-

구조물 설계에서, 축하중과 2축 휨을 동시에 받는 기둥 설계를 자주 접하게 된다. 이러한 부재의 해석과 설계는, 모멘트 평형에 따른 여러 변수들의 값을 동시에 구하기 위하여 반복적인 작업이 필요하기 때문에 많은 시간을 요구한다. 본 연구에서는 축력과 2축 휨을 받는 철근 콘크리트 단주의 극한강도를 계산할 수 있는 컴퓨터 프로그램 COLI을 개발하였고, Green정리를 사용하여 임의 형상의 역학적 특성을 계산할 수 있는 수치 방법을 제시하였다. In structural design, columns subjected to combined axial load and biaxial bending are frequently encountered. The analysis and design of such members, are both time consuming and demanding because an iterative procedure is required in order to simultaneously evaluate a number of variables to achieve moment equilibrium. A computer program COLI is developed to compute the ultimate strength of reinforced concrete short columns subjected to combined compression and biaxial bending in this paper. A numerical procedure using Green's theorem is presented that calculates the mechanical properties of generic shapes.

Nd-Fe-B-Al계 합금의 자기적 특성에 관한 연구

이경섭,박현순,서수정 成均館大學校 科學技術硏究所 1994 論文集 Vol.45 No.2

The effects of Al additions and heat treatment on the magnetic properties of Nd-Fe-B sintered magnets were studied. As the Al content was increased, remanence was reduced and coercivity was increased. Also, as these sintered mangets were heat treated at 600℃, remanence(B_r) and intrinsic coercivity(_iH_c) were increased. In spite of coercivity was increased by the Al addition, maximum energy product(BH)_max was reduced. the highest energy product of 27.9MGOe was obtained in the Nd_15Fe_77B_8 magnet which was heat treated at 600℃.