캘리포니아주의 관상동맥 우회술 위험도보정 결과평가 사례 연구

윤석준,서현주,박형근 한국의료QA학회 2004 한국의료질향상학회지 Vol.11 No.1

새마을 主産團地의 營農實態 比較硏究

徐大振,李宗玉,鄭鉉承,崔元凱,姜鎬允 진주산업대학교 1981 論文集 Vol.19 No.-

The purpose of this study were to find the actual condition of the co-operative group farming in Korea, and to improve the low income Saemaul villages by the adoption of good points in co-operative Group farming. There were so many co-operative farmings in Korea, but all of them were not so successful, Eight co-operative group farmings were chosen to investigate for the above purposes. (Table 1). The tendency of agricultural income was not always true. First of all, Co-op Poultry farm did not follow the order of agricultural income. Because there was an excellent leader who had eliminated the circulation expenses in process of the purchase of feeds and the sale of eggs in common, Second, Seachiodong flower were devived into two parts the cultural flower and the sale flower. The cultural flower meant mainly producing flowers and the sale flower mainly selling flowers to downtown shops in Seoul. The income per householder of the cultual flower was less than that of the sale flower. Consequently, sucessful Co-operative Group farmings had an able leader, and performed production and sale more reasonablly.

골아세포 MC₃T₃-E₁의 증식과 기능에 Insulin Like Growth Factor Ⅰ, Ⅱ 및 부갑상선 호르몬이 미치는 영향

윤현구,정호연,양인명,김성운,김진우,김광원,김영설,최영길,서광식 대한내과학회 1992 대한내과학회지 Vol.42 No.1

MC₃T₃-E₁골아세포군을 이용하여 IGF-Ⅰ과 Ⅱ를 투여하고 DNA합성과 골아세포기능을 측정하기 위해 PTH에 대한 C-AMP반응정도, alkaline phosphatase 활성도를 측정하여 다음과 같은 결과를 얻었다. 1) IGF-Ⅰ과 Ⅱ는 모두 DNA합성이 어느 농도까지는 증식효과를 나타내지만 그 이후에는 억제되는 양상을 보였다. 2) PTH에 대한 골아세포의 C-AMP반응으로 증가되었지만 IGF-Ⅰ과 Ⅱ의 투여시 농도변화에 따른 의미있는 변화는 없었다. 3) 본 실험의 조건에서 alkaline phosphatase 활성도는 증가되지 않았다. 이상의 결과로 MC₃T₃-E₁ 골아세포에 IGF-Ⅰ과 Ⅱ는 세포의 증식을 자극하여 PTH는 C-AMP생성을 촉진하는 효과가 있었다. The effect of insulin-like growth factor (IGF) Ⅰ and Ⅱ on cloned MC₃T₃-E₁ cells that had osteoblastic activity was examined by [³H] thymidine incorporation into DNA, cyclic AMP responsiveness to parathyroid hormone (PTH), and alkaline phosphatase activity. IGF Ⅰ and Ⅱ stimulated the growth and proliferation of osteoblastic cells at 20ng/㎖ and 50ng/㎖, respectively. We next examined the effect of IGF-Ⅰ and Ⅱ on the expression of osteoblastic activity. Adenylate cyclase response of PTH to IGF-Ⅰ and Ⅱ-treated cells showed maximal stimulation at 10 and 50㎚PTH, respectively, but IGF Ⅰ and Ⅱ induced limited activity of osteoblastic function. In conclusion, IGF-Ⅰ and Ⅱ were potent stimulators to the growth of osteoblastic cells but did not have an immediate effect on expression of osteoblastic function in this experiment.

전기집진기 Layout 설계를 위한 소프트웨어 개발

조현덕,윤문철,박기서 한국공작기계학회 1997 한국생산제조학회지 Vol.6 No.1

Electrostatic precipitator is the equipment that separates dust particles from the gas in which they are suspended. Specially, for the construction of industrial electrostatic precipitator, the corporations would send the layout design to a customer to accept an order. Therefore, it is mae a detail drawing after accept ance. Since the layout design of electrostatic precipitator is very complex, it takes time and design errors are included. Thus, for competitiveness in these industries, the development of software for the layout design of electrostatic precipitator is important. In this study, the developed software deals with technical concept and layout design of industrial electrostatic precipitator. By using the software, design time was very short, design errors reduced largely, and the standardization of design could be carried out.

일 대학 병원 마취 · 회복실 간호사의 간호활동 분석

강윤경,김경미,김연이,박혜옥,서광희,송숙녀,이현숙,조의영 대한간호행정학회 2006 간호행정학회지 Vol.12 No.1

Purpose: This study was aimed to specify roles of nurses from the anesthesia and recovery room by analyzing nursing activities as well as anesthesia nursing during surgery. Method: The objects were 12 RNs working in the recovery room of a university hospital located in Incheon. Self-report was performed by measuring stop-watch for five days from May 17th to May 21st in 2004. Research method was designed to record the time and frequency of the nursing activity from anesthesia and recovery room based on nurses' statement and other references for five days. The data were analyzed with descriptive statistics, ANOVA, and t-test via SPSS Win 10.0 program. Result: Nursing activities in anesthesia recovery room were classified into two different characteristics such as direct and indirect nursing activity. The activities consisted of 11 direct nursing areas and 39 nursing activities in anesthesia preparation room. The indirect nursing was classified into 8 nursing areas and 32 nursing activities. The direct nursing was classified into 12 nursing areas and 55 nursing activity. Also, the indirect nursing was classified into 7 nursing areas and 21 nursing activities in recovery room. In terms of prevalence of nursing activities in the anesthesia preparation room, observation and cooperation of anesthesia was the most prevalent activity, drug and eqipment management the second prevalent, and drug administration the third. On the other hand, in the recovery room, the most prevalent activity was vital sign checking and observation, the second most prevalent activity informative activity, and the third body temperature control. Nursing activity time was recorded according to the nursing characteristics. In the anesthesia preparation room, the direct nursing spent for 8092.20 minutes was larger than the indirect nursing spent for 7198.50 minutes. Also, in the recovery room, the direct nursing spent for 2361.16 minutes was larger than the indirect nursing spent for 1134.13 minutes. 4. Nursing activity time was compared to duty shifts. In the anesthesia preparation room, the direct nursing was more prevalent on day shift and the indirect nursing was prevalent on evening shift. However, in the recovery room, both direct and indirect nursing activities were prevalent on day shift. Conclusion: The role of anesthesia and recovery room nurses was analysed according to the time, frequency, and its characteristics.

건축설계실무와 의사결정에 관한 사례 연구 : 공공프로젝트의 경우 Case of Buchon Welfare center and Yonsu Sub-municipal Office

장성준,서윤영,이현창,하종수 명지대학교 대학원 1997 대학원논문집 Vol.1 No.-

The study analyzes a series of decisions made by Building Construction Review Committee on public building construction project. Several government authorities are engaged on the review and required the building client authority to revise the design according to revise items suggested by the committee members ranging from Architectural Planning to other Building Engineering fields. The study delves the legal and design aspects of the review, the meaning of private, semi-public and public function of building, and the construction policy. Two Public building projects were analyzed in terms of revise items. We found some patterns of problem and the current review system works to promote technical aspect of the building and to keep public entity of the projects.

절삭력에 의한 마이크로 엔드밀 변형에 관한 연구

손종인,이학용,손현승,서태일,윤길상 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

Micro end-milling has been becoming an important machining process to manufacture a number of small products such as micro-devices, bio-chips, micro-patterns and so on. Despite the importance of micro end-milling, many related researches have given grand efforts to micro end-milling phenomenon, for example, micro end-milling mechanism, cutting force modeling and machinability. This paper strongly concerned actual problem, micro tool deflection, which causes excessive machining errors on the workpiece. To research this problem, we measured cutting forces in micro end-milling processes. And then we measured about cutting profile for that processes. At last we make a comparison between tool deflection due to cutting force and measurement of cutting profile.

정신분열병 및 정신분열형 장애에 대한 올란자핀의 효과와 안전성

안용민,강대엽,권준수,김창윤,김철응,반건호,신영민,이기철,이동우,이중서,조현상,채정호,김용식 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.4

연구목적 : 본 다기관 공동임상연구는 국내 환자를 대상으로 새로운 항정신병약물인 올라자핀의 치료 효과와 안전성을 확인하고자 시행되었다. 방 법 : 1999년 7월부터 2000년 3월까지 국내 10개 병원에 방문한 정신분열병 및 정신분열형 장애 105명을 대상으로 비대조 개방 임상연구를 시행하였다. 중등도 이상의 정신병 증상을 지니거나, 부작용으로 약물교체가 필요한 경우 또는 기분장애 증상의 치료가 필요한 환자를 대상으로 하였다. 2∼7일간의 약물 배설기간 후에 1일 10mg의 올란자핀을 투여하였고, 이후로 3∼7일 간격으로 용량을 조절하여 총 8주간 투여하였다. 치료 효과는 PANSS(Positive and Negative Syndrome Scale), BPRS(Brief Psychiatric Rating Scale), CGI(Clinical Global Impression-Severity), MADRS(Montgomery-Asberg Depression Rating Scale), HAM-A(Hamilton Rating Scale for Anxiety)로 판정하였다. 안전성 평가는 자발적인 이상반응 보고, 활력징후와 혈액 검사 및 SAS(Simpson-Angus Scale), BARS(Barnes Akathisia Rating Scale), AIMS(Abnormal Involuntary Movement Scale)척도를 이용하였다. 결 과 : 105명중에서 85.7%인 90명이 8주간의 치료를 완료하였다. 평균 최빈 용량은 일일 16.1(±4.7)mg이었고, 종료시점에서의 BPRS전체 점수가 기저 상태에 비해 40%이상 감소된 반응군은 69.5%이었다. PANSS의 양성 증후군과 일반정신병리 뿐만 아니라 음성 증후군 소척도에서도 유의한 감소를 보였으며, 이 감소들은 치료 초기부터 나타나서 8주간 지속되었다. 43.8%의 피험자가 중등도 이상의 우울증상을 같이 지니고 있었으며, 올란자핀에 의해 MADRS와 HAM-A가 유의하게 감소하였다. 치료 기간 동안에 활력징후에는 뚜렷한 변화가 없었으나 체중은 8주간 지속적으로 증가하였다. SAS와 AIMS는 감소하였으며, 정좌불능증을 제외한 나머지 추체외로 증상의 발생비율도 낮았다. 임상적인 증상이나 징후를 동반하지 않는 ALT/SGPT의 상승을 보였지만 프로락틴을 포함하는 대부분의 혈액 검사상 뚜렷한 이상 변화는 없었다. 결 론 ; 비록 본 임상연구가 비대조 개방 임상연구로서 많은 제한점을 가지고 있지만, 올란자핀이 기존 약물에 내약성을 보이거나 기분증상을 동반하는 정신병에 치료 효과가 있었다. 그리고 기존 항정신병약물 치료시에 문제가 되었던 추체외로 증상과 고프르로락틴 혈증을 포함하는 대부분의 부작용면에서 안전성을 보여 주었다. Objective : This multicenter clinical trial was carried out to investigate the efficacy and the safety of olanzpine for the treatment of Korean patients. Mothod : 105 patients with schizophrenia and schizophreniform disorder, visited at 10 mental or university hospitals, had received an open and non-comparative treatment with olanzapine for 8 weeks. Patients had psychotic or depressive symptoms with the severity above moderate degree or intolerable side effects to previous antipsychotics. After a wash-out period of 2-7 days, 10mg olanzapine was prescribed initially to all the patients, and then the dosage could be adjusted within the range of 5-20mg/day of olanzapine by 3-7 days. Results : 90(85.7%) of 105 patients completed the 8-weeks trial and the mean modal dose of olanzapine was 16.1(±4.7%)mg/day. At the end of the trial, 73 patients(69.5%) were classified as responder, which was defined as 40% or more improvement in BPRS(Brief Psychiatric Rating Scale) score comparing to baseline. There was a significant reduction in the scores of PANSS(Positive and Negative Syndrome Scale)and subscales including negative symptom scores and CGI. Also weekly analysis showed that the reductions in scores were kept on for the whole period of the trial. 43.8% of all the patients had depressive symptoms at the baseline and total scores of MADRS(Montgomery-Asberg Depression Rating Scale) and HAM-A(Hamilton Rating Scale for Anxiety) were also reduced after the trials. Vital signs revealed no clinically significant changes but continuous weight gain was observed during the treatment with olanzapine. The scores of SAS(Simpson-Angus Scale) and AIMS(Abnormal Involuntary Movement Scale) for assessing the EPS(extrapyramidal symptoms)and tardive dyskinesia respectively were significantly decreased and only a few patients reported EPS as adverse events. Although mild and clinically non-significant of ALT/SGPT was observed, most laboratory parameters including plasma prolactin level showed to significant changes during the trial. Conclusions : Although this trial had many limitations because it was a non-comparative and open study, olanzapine showed high efficacy on the positive, negative and depressive symptoms in schizophrenia and schizophreniform disorder.In addition to that, olanzapine showed a substantially favorable safety profile, such as low incidence of EPS and hyperprolactinemia.

재래식 시장 지하 상인의 호흡기증상 및 폐기능 조사 연구

이승관,이창규,조경진,임현표,서장훈,최윤수 高麗大學校 倂設 保健大學 保健科學硏究所 1998 保健科學論集 Vol.24 No.1

The prevalence of respiratory symptoms and pulmonary function were studied in a group of 55 whole-sale market merchants Working in underground. As a control group, 55 whitecollar workers was also included in this study. Following results were obtained. A higher complaint for respiratory symptoms(cough, sputum, chest tightness, shortness of breath) was found among merchants than control workers. The measurement value for FVC, FEV1.0, FEV 1.0% in the merchants were reveal to lower figure in comparison with control groups. The measurement Value for MVV, PEF in the merchants were lower than control groups, but was not significant statistically. The pattern of pulmonary ventilation disturbance in the whole-sale market merchant were the same as followings : restrictive disturbance(6 person), abstrictive disturbance(1 person), and combined disturbance(1 person).

만성 어깨 통증을 유발한 양측성 탄력섬유종 1예

장재훈,김강민,김태우,정현광,조윤성,서수홍,이충원 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

Elastofibroma is a rare, benign, soft-tissue tumor that usually located at the inferior pole of the scapula. It is important to differentiate this tumor from other soft-tissue tumors such as sarcoma, fibromatosis, metastatic tumor, and lipoma. A 57-year-old female who complained of chronic both shoulder pain was admitted to our hospital with bilateral, soft tissue masses located in the subscapular region. Ultrasonography, CT and MRI images showed bilateral inhomogeneous tumors that measured 7×3×6 cm. This was compatible with elastofibroma by fine-needle aspiration biopsy. Shoulder pain was gone with decreasing size of masses after conservative treatment and avoiding workload to the shoulder. We present this case with a review of literatures.