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      • 원위 대퇴골의 고립성 골연골종에서 발생한 속발성 연골 육종 1례 보고

        정필현,황장수,강석,김용민,오형호,채동주,김종필 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

        연골육종은 비교적 서서히 자라며 늦게 전이하는 악성 연골 종양으로 알려져 있다. 골 연골종에서 발생한 속발성 연골육종은 발생빈도는 드물며 타부위로의 전이가 적고 악성도가 낮은 경우가 많아 적합한 수술적 치료로서 좋은 예후를 보이는 것으로 보고되고 있다. 본 동국대학교 정형외과학 교실에서는 우측 대퇴골 원위부 골간단부에 생긴 고립성 골 연골종에서 이차적으로 발생한 연골육종을 치험한 바 문헌고찰과 함께 보고하는 바이다. A case of Secondary Chondrosarcoma Arising from Solitary Osteochondroma of the Distal Femur Department of Orthopaedic Surgery, College of Medicine, DongGuk University Phil Hyun Chung M.D., Jung Su Hwang M.D., Suk Kang M.D., Yang Mln Kim M.D., Hyung Ho Oh M.D., Dong Ju Chae M.D., Jong Pil Kim M.D. Chondrpsarcoma is a malignant cartilage-forming tumor that grows slowly and metastasis of this tumor occurs in late stage. Secondary chondrosarcomas arising from a solitary osteocartilaginous exostosis are rare and those have a better prognosis than other chondrosarcomas, and they rarely metastasize. We present our experience with a case of secondary chondrpsarcoma arising in solitary osteochondroma of distal metaphysis of right femur with clinical details.

      • 서울시 역세권 주차장의 운영 합리화에 관한 연구

        고주연,금기정,김현정,김현주,홍영식 明知大學校 産業技術硏究所 1995 産業技術硏究所論文集 Vol.14 No.-

        In this study, we study about park and ride facilities at subway station in seoul, since we have perceived that park and ride facilities at subway's station's serious problem on its operation and usage. We practiced the interviews and transfer rate survey so found these problems of operation usage problem, spatial utilization, private park and ride facilities. Through the analysis of these problem we propose the adequate alternatives and we hope that our study contribute operation rationalization of park and ride facilities at subway station.

      • KCI등재

        스트라이프 패턴을 사용한 패션 디자인 이미지 분석 및 활용방안

        정현 ( Jung¸ Hyun ),우주형 ( Woo¸ Ju Hyung ) 한국기초조형학회 2021 기초조형학연구 Vol.22 No.1

        이 연구의 목적은 스트라이프 패턴을 사용한 패션 디자인의 이미지와 디자인 요소와의 관계를 분석하여 스트라이프 패턴 사용에 따른 특정 이미지의 디자인 전개를 위한 실질적인 아이디어를 제공하는 것이다. 연구방법은 2014년 S/S에서 2018년 S/S까지 패션 컬렉션에 등장한 패션 스타일 중 609점을 대상으로 8개 이미지 범주를 사용하여 패션 이미지를 분석하였고, 통계를 사용하여 디자인의 형태적 요소, 스트라이프의 표현요소, 배색 관계에서 패션 이미지와의 관련성을 도출하였다. 스트라이프 패턴 이 사용된 디자인의 이미지는 로맨틱, 모던, 에스닉, 매니시, 엘레강트, 아방가르드, 스포티, 클래식 순 의 빈도를 보였고, 패션 이미지와 디자인 요소의 연관성 분석, 즉 아이템, 도련 위치, 실루엣, 스트라이프 패턴의 선 방향, 선 모양, 반복 형태, 배색 관계 모두에서 패션 이미지에 따른 유의미한 차이가 발견되었다. 그 결과를 토대로 스트라이프 패턴을 사용한 패션 디자인의 이미지 활용방안을 제시하면 다 음과 같다. 로맨틱 이미지는 허벅지 길이의 X 실루엣 원피스 디자인에 고명도의 무채색과 유채색의 조합으로 이루어진 가로/혼합 방향의 선을 사용, 엘레강트 이미지는 풀렝스 원피스에 명도/채도차를 적게 둔 사선/혼합방향의 선, 클래식 이미지는 수트류에 저명도 중심의 전통적 선염 직물용 세로 방향 스트라이프를 사용, 모던 이미지는 간결한 원피스에 간격의 대비, 명도 차가 뚜렷한 무채색의 규칙적 인 세로 방향 스트라이프 사용, 매니시 이미지는 풀렝스 팬츠 아이템에 규칙적 세로 방향 스트라이프 사용, 스포티 이미지는 탑 & 팬츠/원피스 아이템에 채도차를 강조한 가로 방향 스트라이프 사용, 아방 가르드 이미지는 오벌 실루엣과 착시를 일으키는 불규칙적 반복/혼합 방향의 스트라이프 사용, 에스닉 이미지는 풀렝스 원피스에 가로 방향의 다양한 선들과 탁색조 중심의 멀티배색 등 시각적 복잡성을 강조하는 방향으로 활용하면 패션 이미지의 전달이 더욱 강화될 것으로 제안한다. The purpose of this research is to analyze the relationship between the image of fashion design using stripe patterns and design elements, and to provide practical ideas for the development of a specific image using stripe patterns. The research method was to analyze fashion images using 8 image categories targeting 609 fashion styles that appeared in the fashion collection from 2014 S/S to 2018 S/S. And the relationship between fashion image and formative elements of design, expressional elements of stripes, and color combinations was derived by statistical analysis. The fashion design image using stripe patterns among 609 fashion styles was used in the order of romantic, modern, ethnic, mannish, elegant, avant-garde, sporty, and classic. Significant differences were found according to the analysis of the relevance between fashion image and design elements, such as item, hem-line position, silhouette, line direction, line shape, line repetition, and color scheme. Based on the results, suggestions for utilization of the fashion image using stripe patterns are as follows. It can be enhanced that romantic image by X silhouette one-piece dress above knee-length using horizontal/mixed directional lines consisting of white and tinted color combination; elegant image by full-length dress using diagonal/mixed lines with similar value/saturation in colors; classic image by skirt/pants suits using traditional vertical stripes for yarn-dyed fabrics with low values in colors; modern image by simple one-piece dress using regular vertical stripes with clear intervals between lines and value contrast in achromatic colors; mannish image by full-length pants using regular vertical stripes; sporty image by pants/one-piece items using horizontal stripes with saturation contrast in colors; avant-garde image by oval silhouette items using irregularly repeated multi-directional stripes which cause optical illusion; and ethnic image by full-length one-piece dress using various horizontal lines such as zigzag with tone-downed multi-colors which cause visual complexity.

      • KCI등재후보

        Inducing apoptpsis by the inhibition of c-myb in oral squamous carcinoma cell line, KB cell

        Lee,Jung-Chang 대한구강생물학회 2007 International Journal of Oral Biology Vol.32 No.4

        Oral squamous cell carcinoma (OSCC) is the most commonmalignancy and is a major cause of worldwide cancer mortality.The proto-oncogene c-myb plays an important role in regulationof cell growth and differentiation, and it is expressed at highlevels in hematopoietic cells and many other types of cancers.However, the function of c-myb is not well known in OSCC.The present study aimed to reveal the function of c-myb and totest the alternation of cell growth and signaling by c-myb inOSCC. In this study, c-myb and dominant-negatibe myb(DN-myb) were expressed in an adenovirus-mediated gene deliverysystem to KB cells. The over-expressed c-myb broughtincreased cellular proliferation compared with control cells.However, DN-myb infected KB cells showed significantreduction of cell growth and enhanced induction of apoptosis toactivate PARP and caspase 9. c-myb induced increase of IGF-I,-II and IGF-IR expressions while DN-myb down-regulatedthese expression. Activation of ERK and Akt/PKB pathwaywas shown only in c-myb transduced cells. These findingssuggest that the role of c-myb in cell growth of oral cancer cellsis partially mediated through the modulation of IGFs, ERK andAkt/PKB. From this results, DN-myb is strongly recommendedas a curable gene for the treatment of c-myb dependentmalignancies such as OSCC.

      • KCI등재
      • KCI등재

        The Identification of Aucklandiae Radix, Inulae Radix, Vladimiriae Radix and Aristolochiae Radix, Using Macroscopic, Microscopic and Physicochemical Methods

        Yoon, Jee-Hyun,Park, Ha-Yeong,Kim, Tae-Ju,Lee, Seung-Ho,Kim, Jung-Hoon,Lee, Guem-San,Kim, Hong-Jun,Ju, Young-Sung The Society of Korean Medicine 2014 대한한의학회지 Vol.35 No.4

        Objectives: This study aimed for establishing the discriminative criteria for Aucklandiae Radix, Inulae Radix, Vladimiriae Radix and Aristolochiae Radix, which can be confused as 'Mokhyang', because of similar appearances and synonyms. Methods: Morphological characteristics of dried herbal medicines were compared by macroscopic observation. To examine microscopic features of 'Mokhyang', paraffin embedding and the staining by using Ju's method were conducted. Physicochemical experiments were performed using HPLC analysis and antioxidant assay. Results: The types of stem, phyllotaxy and leaf shape were chosen as macroscopic criteria and the size, oil spots, color and root top as well as phloem and central cylinder were compared using microscopic features. The HPLC results showed different amounts of costunolide and dehydrocostuslactone among Aucklandiae Radix, Inulae Radix and Vladimiriae Radix. However, Aristolochiae Radix only contained aristolochic acid. The antioxidant assays also showed that Vladimiriae Radix exhibited strongest antioxidant activity followed by Aucklandiae Radix, Inulae Radix and Aristolochiae Radix. Conclusions: These results demonstrate that macroscopic, microscopic and physicochemical methods would be useful tools for the discrimination of 4 kinds of 'Mokhyang'.

      • S-580 : Vitamin D and carotid subclinical atherosclerosis in SLE

        ( Chang Bum Bae ),( Ju Yang Jung ),( Bo Ram Go ),( Hyun Ah Kim ),( Chang Hee Suh ) 대한내과학회 2013 대한내과학회 추계학술대회 Vol.2013 No.1

        Vitamin D and carotid subclinical atherosclerosis in SLE Chang-Bum Bae, Ju-Yang Jung, Bo-ram Go, Hyun-Ah Kim, Chang-Hee Suh Department of Rheumatology, Ajou University School of Medicine, Suwon, Korea Introduction Atherosclerosis develops earlier in systemic lupus erythematosus (SLE) and is the important cause of mortality. It has been suggested that vitamin D deficiency contributed cardiovascular disease and immune dysregulation in SLE. Methods One-hundred two female patients with SLE and 52 normal controls (NC) were recruited. The carotid artery intima-media thickness (cIMT) and plague were assessed by B-mode ultrasound at the carotid artery level. Vitamin 25(OH)D3 levels were checked by immunoradiometric assay using the Bio-Line 25(OH)D3-Ria CT kit (Bio-Line S.A., Belgium). Disease activity markers were checked at the time of enrollment. Results The cIMT of SLE is 0.41±0.08mm, which is higher than NC (0.37±0.11 mm, p=0.012). Also, carotid artery plague index (PI) of SLE is higher than NC (0.68±1.39 vs 0.26±0.87, p=0.026). The cIMT was correlated with age (r=0.442, p<0.001), body mass index (r=0.246, p=0.013), waist-hip ratio (r=0.245, p=0.013), SLE disease activity index (r=0.239, p=0.016), taking aspirin (r=0.244, p=0.013), and the carotid artery PI was correlated with renal involvement (r=0.224, p=0.023) in patients with SLE. Vitamin 25(OH)D3 was not showed correlation with cIMT and carotid artery PI. Also, it was not correlated with disease activity markers. Conclusion In patients with SLE, the risk of cardiovascular disease measured by cIMT and carotid artery plaque was higher than NC, which may be derived from systemic inflammation. However, vitamin D levels were not showed significant correlations with carotid subclinical atherosclerosis. It may be not suitable to assess vitamin D as marker of disease activity or subclinical atherosclerosis.

      • KCI등재후보

        2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

        이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

        목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

      • CWOS와 황토를 이용한 농축·소화슬러지의 탈수성에 관한 연구

        정병길,고현웅,주윤경,정유진,이징연 동아대학교 환경문제연구소 2002 硏究報告 Vol.25 No.1

        Every year, 190,000 tons of oystershell are wasted from many oyster farms. And the fact that the main components of oystershell are CaO and Al₂O₃ which are chemically similar to those of lime leaded to an assumption that oystershell can be used as raw materials for synthesizing dewatering conditioner. In this study, the Jar-Test and the Bu˝chner funnel test were proceeded for the assessment of dewaterability of a thickened sludge and digested sludge. And TTF(Time To Filter), SRF(Specific Resistence Filtration) and TS(Total Solids) were adopted as the valuation indices of sludge dewaterability. Dewatering conditioner which composed of both oystershell and loess is much dewaterable than the one composed of only oystershell. And in the course of combining of oystershell and loess, the following fact was found that the dewaterability of the combination which have the higher ratio of oystershelI than that of loess is superior. Eventually, the most suitable ratio of dewatering conditioner complex is 9 : 1 (oystershell : loess) in treating not only thickened sludge but also digested sludge. In conclusion, the conditioner synthesized from waste oystershell and loess seems to be used as a splendid alternative material for the dewatering conditioner treating the sludge of sewage.

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