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GC 연삭숫돌을 이용한 탄소섬유 에폭시 복합재료의 평면 연삭특성에 관한 연구
한흥삼,윤혁중,이동주 韓國工作機械學會 2000 한국생산제조학회지 Vol.9 No.4
Since carbon fiber epoxy composite materials have excellent properties for structures due to their high specific strength, high specific modulus, high damping and low thermal expansion, the hollow shafts made of carbon fiber epoxy compos-ites have been widely used for power transmission shafts for motor vehicles, spindles of machine tools, motor base, bear-ing mount for tool up and manufacturing. The molded composite machine elements are not usually accurate enough for mechanical machine elements, which require turning, drilling, cutting and grinding. The experiment are surface grinding of the grinding wheel GC60 to the car-bon fiber epoxy composite specimen with respect to stacking angle [0]_nT, [45]_nT, [90]_nT on the CNC grinding machine. In this paper, the surface grinding characteristics of composite plate, which are surveyed experimentally and analytically with respect to the grinding force, surface roughness and wheel loading according to the variable depth of cut, wheel velocity and table feed rate are investigated.
체외수정시술을 위한 과배란유도시 Highly Purified FSH 사용 군과 FSH / hMG 사용 군과의 비교연구
최기동(Ki Dong Choi),홍민(Min Hong),김일한(Ill Han Kim),최창익(Chang Ik Choi),오갑영(Gab Young Oh),한혁동(Hyuck Dong Han) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.8
불임환자에서 체외수정을 위한 과배란 유도시 사용되어지는 FSH 제재로는 0.01 IU의 LH를 함유하고 있는 FSH와 약0.006 IU의 LH를 함유하고 있는 Highly Purified FSH(FSH-HP)등이있다. 불임환자의 체외수정을 위한 과배란 유도시 FSH 제재만으로도 정상적인 난포의 성장 및 임신이 가능하며 또한 많은 양의 LH는 임신율을 감소 시키는 것으로 알려져왔다. 따라서 본연구에서는 FSH-HP만 사용한 군과 FSH/hMG를 사용한군 사이의 체외수정을 위한 과배란 유도결과를 비교 분석하기 위하여 시행하였다. 본 연구는 체외수정을 위한 과배란 유도 총 280주기중 FSH-HP사용군이 111주기이고, FSH/hMG사용군이 169주기였다. 각 연구군에서 불임환자의 연령, 투여된 Gonadotropin의 양 및 기간,이식한 배아의 수, 자궁내막의 두께, 수정율 등은 유의한 차이가 없었다. 채취된 난자의 수는 두 투여군 사이에 유의한 차이가 없는 반면 hCG 투여일의 혈중 E2 농도는FSH/hMG 투여군에 비하여 FSH-HP투여군에서 유의하게 낮았다. 배아의 질면에서는 GradeⅠ,Ⅲ,Ⅳ 의 배아에서는 두군간차이는 없었으나 GradeⅡ 의 경우 0.22±0.67개와 0.06±0.24개로 FSH-HP 투여군이 유의하게 높았으며 배아의 GradeⅠ 과Ⅱ를 합한 경우 FSH-HP투여군이 2.56±1.78, FSH/hMG투여군이2.06±1.73으로 FSH-HP투여군이 유의하게 높았다. 임신율에 있어서는 38.8% Vs 34.2% 로 FSH-HP 투여군이 높은경향을 보였으나 유의한 차이는 없었다. 이와같은 결과로 볼 때 FSH-HP 사용이 FSH/hMG 사용보다 더 양질의 배아를 얻을수 있었고 FSH-HP 투여군이 임신율에 있어서도 유의한 차이는 아니지만 높은 경향을 보였으므로 효과적인 과배란 유도의 한 방법으로 사용되어질수 있을것으로 생각되어진다. Objective : It is known that normal follicular growth and pregnancy are possible using Follicular stimulating hormon(FSH) alone during controlled ovarian hyperstimulation(COH) for IVF-ET. The purpose of this study was to compare and analize the results of COH for IVF-ET between a group using only FSH-HP and a group using FSH/hMG Method : 111 cycle of the total 280 COH for IVF-ET cycles belonged to the FSH-HP group, and the FSH/hMG group accounted for remaining 169 cycles. The amount of gonadotropin administered, the duration of hormonal therapy, the number of embryos transfered, the endometrial thickness, and the pregnancy rate were compared between the two groups and statistically analized using the t-test. p values less than 0.05 deemed statistically significant. Result : There were no statistical differences on the amount of gonadotropin administered, the duration of hormone therapy, number of oocytes retrieved, nor the endometrial thickness between the two groups. However,the serum E2 level was significantly lower, and the number of embryos of high quality(GradeⅠandⅡ) significantly higher in the FSH-HP group. In pregnancy rate, FSH-HP group shows higher than FSH/hMG group(38.8% VS 34.2%). but the difference was not large enough to be considered statistically significant. Conclusion : The results of this study show that compared to using FSH/hMG, treatment with FSH-HP alone allowed the retrieval of more embryos of high quality, and although not statistically significant, achieved a higher pregnancy rate, thus indicating that it can be used as an effective method for COH.
Han, Ji H.,Shin, Hanho,Rho, Jun G.,Kim, Jung‐,Eun,Son, Dong H.,Yoon, Juhwan,Lee, Yong J.,Park, Jung‐,Hyuck,Song, Byung J.,Choi, Chang‐,Sik,Yoon, Seul G.,Kim, Il Y.,Lee, Eun K.,Seong, Blackwell Publishing Ltd 2018 DIABETES OBESITY AND METABOLISM Vol.20 No.9
<P>Conclusions: These results suggest that peripheral CB1R blockade improves obesity-induced insulin resistance by suppressing adipose tissue inflammation via the NLRP3 inflammasome.</P>
Impact of multi-vessel vasospastic angina on cardiovascular outcome
Han, Seung Hwan,Lee, Kwan Yong,Her, Sung Ho,Ahn, Youngkeun,Park, Keun-Ho,Kim, Dong-Soo,Yang, Tae-Hyun,Choi, Dong-Ju,Suh, Jung-Won,Kwon, Hyuck Moon,Lee, Byoung Kwon,Gwon, Hyeon-Cheol,Rha, Seung-Woon,Jo Elsevier Scientific Publ. Co 2019 Atherosclerosis Vol.281 No.-
<P><B>Abstract</B></P> <P><B>Background and aims</B></P> <P>Since clinical characteristics and prognosis of patients with multi-vessel vasospastic angina (VSA) are not clear, we investigated the nature and prognosis of multi-vessel VSA in Koreans.</P> <P><B>Methods</B></P> <P>Among 2960 patients enrolled in the VA-KOREA (Vasospastic Angina in Korea) registry, 104 definite multi-vessel VSA patients, 163 single vessel VSA patients and 737 non-VSA patients were identified using the intracoronary ergonovine provocation test.</P> <P><B>Results</B></P> <P>Multi-vessel VSA and single vessel VSA groups showed similar baseline characteristics and medical treatment on discharge, but different from the non-VSA group. The primary composite endpoint (cardiac death, acute coronary syndrome, and symptomatic new onset arrhythmia) over a 36-month follow-up period was significantly higher in the multi-vessel VSA group than in the single vessel VSA and non-VSA groups (8.7% <I>vs</I>. 1.8% and 1.1%, each log-rank <I>p</I> < 0.05, respectively). The rate of death and acute coronary syndrome of the multi-vessel VSA group was higher than in the single vessel VSA and non-VSA groups (5.8% <I>vs.</I> 1.2% and 0.9%, each log-rank <I>p</I> < 0.05, respectively). In addition, multi-vessel VSA was an independent predictor of the primary composite endpoint at 36 months (HR 8.5, 95% CI [2.6–27.2], <I>p</I> < 0.0001).</P> <P><B>Conclusions</B></P> <P>Patients with multi-vessel VSA had worse clinical outcomes than single vessel VSA and non-VSA groups, suggesting that the existence of multi-vessel VSA itself is highly prognostic.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Prevalence of multi-vessel vasospastic angina (VSA) is not low (39.0%) by strict definition. </LI> <LI> Baseline characteristics of multi-vessel and single vessel VSA groups were similar, but different from non-VSA group. </LI> <LI> Multi-vessel VSA group had worse clinical outcomes than the single vessel and non-VSA groups. </LI> <LI> Multi-vessel VSA itself is one of the independent predictors for MACE. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>