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      • 유체-구조물-지반 상호작용을 고려한 항만구조물의 지진응답 해석

        김두기,류희룡,장성규,서형렬 국립7개대학공동논문집간행위원회 2004 공업기술연구 Vol.4 No.-

        This paper presents the result of a study on the fluid-structure-soil interaction(FSSI) of a port structure under earthquakes. In this analysis, the fluid is modeled by the 4-node element which is a modification of a structural plane elements, and the port structure and foundation is modelled by the plane strain elements. Since the present method directly models the fluid-structure-soil interaction system by finite elements, if can be easily applied to the dynamic analysis of a 2-D port structure with complex geometry. Finally, results of seismic analyses are presented and compared to those of the seismic coefficient and the added mass methods.

      • KCI등재후보
      • KCI등재

        골반부 방사선 치료 환자에서 in vivo 선량측정시스템의 임상적용

        김보경,지의규,허순녕,이형구,하성환 대한방사선 방어학회 2002 방사선방어학회지 Vol.27 No.1

        방사선치료 시 종양에 정확한 양의 방사선을 조사하는 것은 국소 재발을 방지하고 합병증의 빈도를 낮춰 효과적인 치료를 가능하게 하는 중요한 요소이다. 종양에 조사되는 방사선량의 측정을 통해 치료의 정확성을 확인하기 위한 여러 방법들이 시도되고 있으며, 투과선량을 이용한 측정법도 그 중 한 예로 비침습적이며 매 치료 시 측정이 가능한 장점을 가지고 있다. 본 교실에서는 투과선량을 이용한 in vivo 선량측정시스템과 임의의 치료 조건에서 투과선량을 계산하기 위한 알고리즘을 개발하였다. 본 교실에서 개발한 in vivo 선량측정시스템의 단기간 및 장기간의 재현성을 확인하고, 환자의 방사선치료에서의 이용 시 발생할 수 있는 문제점을 파악하고 알고리즘의 정확성을 확인하기 위하여 본 연구를 시행하였다. 2000년 7월 25일부터 8월 14일 사이에 방사선치료를 시행 받은 환자 66명을 대상으로 투과선량의 측정을 시행하였으며, 이 중 골반부위의 방사선 치료를 3회 이상 시행 받은 11명의 환자를 대상으로 측정선량과 예측선량의 비교 분석을 시행하였다. 측정시스템의 재현성의 확인을 위하여 환자의 치료 전 및 치료 중 매시간 기준 조사조건에서 측정치를 확인하였다. 일별 몇 일 중 변동은 ±2% 이내로 재현성을 확인할 수 있었다. 본 시스템의 사용 시 별다른 문제점은 없었으나, 2명의 흉부 치료환자에서 투과선이 치료용테이블의 측면 금속을 관통하는 문제가 발생하였다. 골반부위 환자에서는 골반부위의 불균질조직에 의한 영향의 확인을 위하여, CT 및 simulation film을 이용하여 골 조직의 두께를 확인하여 보정 전 및 후의 값을 비교하였다. 전후방 및 후방조사야의 경우 골 조직의 보정을 시행하지 않은 경우 평균 오차가 -5.20%내지 +2.20%이었으며, 보정을 시행한 경우 -0.62%내지 +3.32%로 환자에 따라 정도의 차이는 있으나 골 보정이 필요함을 확인할 수 있었다. 측정치와 예측치 간 오차의 표준편차는 1.19%내지 2.46%로서 재현성이 높음을 확인할 수 있었다. 좌우 측방조사야에서 골 보정을 시행하지 않은 경우 평균오차는 -10.80%내지 +3.46%로서 골 조직의 보정이 필요하지 않은 1인의 환자를 제외하면 모두 음수 값을 지녔고, 보정을 시행한 경우 -0.55%내지 +3.50%의 평균오차를 지녀 골 보정의 필요성을 확인할 수 있었다. 측정치와 예측치 간 오차의 표준편차는 1.09%내지 6.98%로 전후방조사야의 경우보다 재현성이 낮음을 알 수 있었다. 복와위로 방사선치료를 시행 받은 환자의 경우를 제외하면, 표준편차는 1.09%내지 3.12%로 1례 외에는 2.57% 이내로 재현성이 높음을 확인할 수 있었다. 본 실험을 통하여 in vivo 선량측정시스템의 안전성과 재현성을 확인할 수 있었다. 정확한 예측치를 얻기 위하여 불균질 조직이 조사야에 포함되는 경우 보정이 요구되며, 골반의 경우 골 조직의 보정이 중요한 요인임을 알 수 있었다. 이를 위하여 불균질 조직에 대한 정확한 정보가 요구되며, 이는 CT 영상을 이용하는 것이 크게 도움이 되리라 생각된다. The accuracy of radiation dose delivery to target volume is one of the most important factors for good local control and less treatment complication. In vivo dosimetry is an essential QA procedure to confirm the radiation dose delivered to the patients. Transmission dose measurement is a useful method of in vivo dosimetry and it's advantages are non-invasiveness, simplicity and no additional efforts needed for dosimetry. In our department, in vivo dosimetry system using measurement of transmission dose was manufactured and algorithms for estimation of transmission dose were developed and tested with phantom in various conditions successfully. This system was applied in clinic to test stability, reproducibility and applicability to daily treatment and the accuracy of the algorithm. Transmission dose measurement was performed over three weeks. To test the reproducibility of this system, X-ray output was measured before daily treatment and then every hour during treatment time in reference condition (field size; 10 cm x 10 cm, 100 MU). Data of 11 patients whose pelvis were treated more than three times were analyzed. The reproducibility of the dosimetry system was acceptable with variations of measurement during each day and over 3 week period within ±2.0%. On anterior- posterior and posterior fields, mean errors were between -5.20% and +2.20% without bone correction and between -0.62% and +3.32% with bone correction. On right and left lateral fields, mean errors were between -10.80% and +3.46% without bone correction and between -0.55% and +3.50% with bone correction. As the results, we could confirm the reproducibility and stability of our dosimetry system and its applicability in daily radiation treatment. We could also find that inhomogeneity correction for bone is essential and the estimated transmission doses are relatively accurate.

      • SCOPUSKCI등재

        Malassezia sympodialis가 동정된 신생아 Malassezia 농포증 1예

        김휘준,이무형,안규중 대한의진균학회 2001 대한의진균학회지 Vol.6 No.4

        Neonatal Malassezia pustulosis can be defined as pustules on face and neck, age at onset younger than 1 month, isolation of Malassezia by direct microscopy in pustular material, elimination of other causes of neonatal pustuloses, and response to topical ketoconazole therapy. We report a case of neonatal Malassezia pustulosis in a 20-day-old male. Direct microscopic examination on smears for pustules showed forms of Malassezia yeasts and culture yielded Malassezia sympodialis. The lesions were remarkably improved by topical ketoconazole cream for 14 days. [Kor J Med Mycol 6(4): 229-231] Key Words: Neonatal Malassezia pustulosis

      • 요통환자에 대한 임상적 고찰 : 한·양방 협진병원 내원 환자를 중심으로

        김형태,류규수 慶山大學校 保健福祉硏究所 1997 保健福祉硏究 Vol.1 No.-

        With 160 lumbago patients (85 inpatients and 75 outpatients) who received both Oriental and Western medical treatment from December, 1994 to April, 1995 at the acupuncture section and rehabilitation section of the H Hurb Hospital which is located in Seoul, a clinical study on the realities of lumbago was carried out. Findings from such a study are as follows: 1. It appeared that regarding the distribution of sex, 80 lumbago patients(50%) were male while the same number of lumbago patients were female, thereby presenting a distributional rate of male and female, 1:1 ; regarding the distribution of age groups, from the age group which consists a large number of lumbago patients, they were the age group of 30s 44 lumbago patients(which is 27.5% of total lumbago patients), age group of 60s or more than that, age group of 50s, and age group of 20s ; regarding the distribution of job, from the group which consists a large number of lumbago patients, they were the group of housewives, group of the unemployed(or the aged), group of clerical workers, group of professional job, etc. 2. It appeared that the causes of the attack of lumbago are unknown etiology 56 lumbago patients(35.0%), heavy lifting 39 patients(24.4%), longtime standing 24 patients(15%), sprain 20 patients(12.5%), and accidents and contusion 11 patients(6.9%) in the order from the most case. 3. Regarding the relapse rate among the subjects, it appeared that 106 lumbago patients(66.2%) had more than relapse, and 54 patients(33.8%) were newpatients; and among the patients having more than relapse, the case of 3rd recurrence outnumbered the case of 2nd recurrence. Regarding the distribution other relapse rate according to age groups, it appeared that the most case was in the group of 60s and more than that with 28 patients(26.2%), then the next case in the group of 30s, then the case in the group of 20s, and then the case in the group of 50s. Regarding the distribution of the relapse rate according to job, it appeared that from the most case, there were 28 lumbago patients of housewives(28.0%), 27 patients(24.7%) of theunemployed(an aged population), and 19 patients(17.8%) of clerical workers. 4. Regarding the distribution of the causes of relapse, it appeared that the most case was due to unknown etiology with 43 patients(40.2%), then the next case due to heavy lifting, then due to longtime standing, then due to sprain, and then due to accidents and contusion. Regarding the distribution of the causes of relapse accoriding to age groups, it appeared that the most case was due to unknown etiology which was seen in all the age groups ; in the age group of 30s, due to heavy lifting, then due to longtime standing, and then due to sprain; and in the age group of 60s and more than that, due to heavy lifting, then due to longtime standing, and then due to contusion. Regarding the causes of relapse according to job, it appeared that the most case was due to unknown etiology or no special cause of attack ; in the group of the unemployed(an aged population), due to heavy lifting, and then due to longtime standing in the order from the most case ; in the group of service workers, due to heavy lifting, and then due to contusion ; and in the group of clerical workers, due to heavy lifting, then due to sprain, and then due to longtime standing in the order from the most case. 5. Regarding the results of the combined treatment of Oriental medicine and Western medicine, it appeared that 86 patients(53.8%) were in a superior state, 45 patients(28.1%) in a good, satisfactory state, 15 patients(9.4%) in the evenly improved state, 8 patients(5.1%) in a lightly improved state, and 6 patients(3.8%) in a poorly improved or inferior state, showing a valid rate of 96.2%. 6. Regarding the required period of medical treatment according to the case history of lumbago, it appeared that the acutest patients(82 patients : 51.3%) required 17.5days, the semi-acute(29 patients ; 18.1%) 20.9 days, the acute(10 patients ; 12.5%) 28.1 days, and the chronic(29 patients; 18.1%) 30.5 days(p=0.0874). Regarding the required period medical treatment according to the degree of the pain, 40 patients(25.2%) having an pain in a degree of an even ache required 18.2 days, 87 patients(54.6%) having a severe pain 22.6 days, 26 patients(16.4%) having a very severe pain 27.9 days, and 7 patients(4.6%) having a light pain 29.4 days(p=0.5857). 7. Regarding the period of medical treatment according to the diagnosed names of lumbago, it appeared that in Western medicine, 57 patients(35.7%) of Accute back pain required 10.1 days, 20 patients(12.4%) of Chronic back pain 24.3% days, 57 patients(37.0%) of HNP 26 days, 19 patients(11.9%) of degenerative spondylosis 26.5 days, 4 patients(2.5%) of Spondyolisthesis 33.3 days, 1 patients(0.6%) of Spinal stenosis 25.5 days(p=0.0108) ; in Oriental medicine, 29 patients(18.2%) of Shensu-zwasum lumbago 31.7% days, 46 patients(28.8%) of Shensu lumbago 25.7 days, 27 patients(16.9%) of Zwasum-yihyul lumbago 20.6 days, 55 patients(34.4%) of Zwasum lumbago 15.5 days, 2 patients(1.3%) of Yihyul lumbago 21 days, and 1 patients(0.6%) of Shi lumbago 2 days(p=0.2762). 8. Regarding the period of medical treatment according to the diagnosed names of lumbago in case of new patients and old patients(or relapsed patients), it appeared that new patients required a period of medical treatment of 18.4 days in general or average for curing lumbago while old patients required a period of 24.1 days in general or average ; this indicates that new patients were cured earlier than old patients. Regarding the period of medical treatment according to the diagnosed names of lumbago, it appeared in Oriental lumbago, when the diagnosed names was Zwasum lumbago and Yihyul lumbago, the required period of medical treatment was short ; in Western medicine, when the diagnosed name was Acute back pain, the required period of medical treatment was short ; in Western medicine, when Shensu lumbago and Shensu lumbago develop into Chronic back pain and HNP, medical treatment of them required more days ; regarding the period of medical treatment in case of new patients and old patients, new patients required a shorter period than old patients ; in particular, in case of Shensu lumbago in Oriental medicine and Chronic back pain in Western medicine, it was understandable that the required period of medical treatment necessitates more days.

      • 중추성 요붕증이 동반된 랑게르한스 세포 조직구증 1예

        김진호,문준성,문선중,이지은,최재원,은미정,천경아,조인호,윤지성,원규장,이경희 신덕섭,이형우 영남대학교 의과대학 2005 Yeungnam University Journal of Medicine Vol.22 No.2

        Central diabetes insipidus (DI) is a syndrome characterized by thirst, polydipsia and polyuria. Langerhans cell histiocytosis is one of the etiologies of DI. Recently we experienced a central DI associated with Langerhans cell histiocytosis. The 44 years old female patient complained right hip pain polydipsia and polyuria. We carried out water deprivation test. After vasopressin injection, urine osmotic pressure was increased form 109mOsmol/Kg to 327mOsmol/Kg (300%). Brain MRI showed a thickened pituitary stalk and at hot bone CT.CT guided biopsy revealed abnormal histiocytes proliferation and abundant lymphocytes, The final diagnosis was central DI associated with systemic Langerhans cell histiocytosis invading hip bone, L-spine and pituitary stalk. Desmopressin and etoposide chemotherapy were performed to the patient.

      • 고상 에피텍시 성장을 이용한 elevated source/drain 공정연구

        金湘薰,崔在植,崔圭鎭,金亨駿 弘益大學校 科學基術硏究所 1999 科學技術硏究論文集 Vol.10 No.2

        Recently, semiconductor devices require the ultrashallow junctions and low leakage current. Self-implantation to make preamorphization prevents channeling and minimizes junction depth. But in this way, implantation with high energy makes defects like dislocation loop in depletion region and interface between amorphous silicon and silicon wafer. But solid phase epitaxy using low pressure chemical vapor deposition prevents channeling, allows the easy control of junction depth by amorphous layer thickness, and improves the conventional processes. Amorphous silicon films in source and drain by LPCVD are elevated from the Si substrate. This structure is called "elevated source/drain". The elevated source/drain process improves metal contact and simplify the fabrication process. Usually, the amorphously-deposited Si films by chemical vapor deposition are crystallized to polycrystalline films due to a formation of SiO₂layer at the amorphous Si/Si substrates interfaces. Formation of SiO₂layer on Si surface can be effectively prevented by flowing the Si₂H?? gas during the heating-up procedure for amorphous Si depositions. In this way, amorphously deposited Si layer onto (100) Si substrates was grown epitaxially during the post-deposition heat treatments. The suppression of surface SiO₂can be explained in terms of adsorption of SiHx adspecies, instead of oxygen from residual gases in the reactors, to Si surfaces after desorption of hydrogen from H-passivated Si surfaces. Employing Si₂H?? flowing and solid phase epitaxial growth, high-quality epitaxial Si layer was obtained at low temperatures below 500℃ without conventional high temperature cleaning procedures. Amorphous Si films on Si substrate are epitaxially grown and amorphous Si films on SiO₂layer remain as amorphous with proper heat treatments. Uncrystallized amorphous Si films on SiO₂layer can be selectively etched using the HNO₃/HF/HNO₃/CH₃COOH solution with proper mixing ratio and elevated source/drain regions were formed.

      • 승온시 Si₂H가스 주입을 이용한 저온 Si 에피택시에 관한 연구

        金亨駿,申東勳,崔圭鎭,金東玄 弘益大學校 科學技術硏究所 1998 科學技術硏究論文集 Vol.9 No.2

        In this study, we studied on the low temperature Si epitaxy growth for Si epitaxial growth temperature below 650。C. Usually, the Si epitaxy films by chemical vapor deposition are crystallized to polycrystalline films due to a formation of SiO₂layer at the epitaxial Si/Si substrates interfaces. Formation of SiO₂layer on Si surface can be effectively prevented by flowing the Si₂H?? gas during the heating-up procedure for Si deposition. In this way, Si epitaxial layer onto (100) Si substrates was grown epitaxial layer during the post-deposition heat treatments. The suppression of surface BIO₂can be explained in terms of adsorption of SiH?? adspecies, instead of oxygen from residual gases in the reactors, to Si surfaces after desorption of hydrogen from H-passivated Si surfaces. Employing Si₂H?? flowing and epitaxial growth, high-quality epitaxial Si layer was the low temperature below 650。C without conventional high temperature cleaning procedures. And the crystallinity of epitaxial layer measured as deposition conditions using ultraviolet reflectance. AS this results, we could be aquaired process temperature region for high-quality low temperature Si epitaxial growth.

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