노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

부모효율훈련(P.E.T.) 프로그램의 유아교육기관에의 적용 가능성에 대한 기초연구

노경혜 기전여자대학 1995 論文集 Vol.15 No.-

The purpose of this study is to examine the way to apply the concept of Parent Effectiveness Program to the early childhood educational situation in Korea. As a practical program on the relationships between children and parent, P.E.T. program contains following basic principles : the inconsistency principle and the principle of problem ownership. This program also introduces some effective methods on problem solving of child-parent relations such as active listening, I-message, and no-lose method. Even though this program is very practical and effective in developing child-parent relations in general, further researches and studies that take deep considerations on their socio-economic status and regions in Korea should be conducted.

發癌物質을 投與한 쥐의 免疫細胞에 미치는 抗癌劑 및 人蔘成分의 影響

鄭魯八,朴韓雨,全惠京 연세대학교 대학원 1991 延世論叢 Vol.27 No.1

To investigate the effects of the anti-cancer drug (CY, γ-IFN) and ginseng saponin components on the rat immunocytes treated with hepatocarcinogen, the γ-GT(gamma-glutamyl transpeptidase) activity in rat liver homogenates and the amounts of α-FP( alpha-fetoprotein) in peripheral blood system were assayed. And the tumoricidal activities of peritoneal Mφ of mouse preinjected with cancer cells were assayed in vitro. The amount of α-FP using anti-α-FP antibody in peripheral blood system was undetectable and the γ-GT activity was decreased as much as 60% by ginseng saponin and the anti-cancer drug. In the early stage of cancer development those agents suppressed effectively the proliferation of transformated cell into tumor cell and resulted in an increase of tumoricidal activities through the activiation of Mφ in vitro. The above results suggest that the decrease of γ-GT activity in liver homogenates and the disappearance of alpha fetoprotein in peripheral blood system resulted (rom the elimination of precancerous cell through the potentiation of Mφ by ginseng saponin

입원진료비 상승요인 분석

한혜경,이필도,노인철 한국인구보건연구원 1990 保健社會論集 Vol.10 No.2

3차 의료기관에 입원한 노숙환자에서 감염질환의 유병율

함세운,남기석,노혜진,홍경득,황래석,방지환,신형식 대한감염학회 2007 감염과 화학요법 Vol.39 No.4

목적 : 3차 의료기관에서 입원치료를 받았던 노숙자를 대상으로 감염성 질환의 유병율을 알아보고자 하였다. 재료 및 방법 : 2002년 1월부터 2004년 8월 사이에 국립의료원에서 입원 치료를 받았던 269명의 노숙자 환자들을 대상으로 의무기록을 조사하였다. 결과 : 연구 기간동안 입원치료를 받은 총 269명의 노숙자 환자 중 남자가 249명(92.9%), 여자가 19명(7.1%)이었다. 감염질환의 유병율은 B형 간염이 228명 중 15명(6.6%), C형 간염 113명 중 8명(7.1%), 결핵은 269명중 19명(7.1%), VDRL 양성인 경우는 234명 중 25명(10.7%), 항사람면역결핍바이러스항체 양성은 130명중 2명(1.5%)이었다. B형 간염표면항원에 대한 항체 형성자는 118명(51.7%), 항체 미형성자는 95명(41.7%)이었다. 결핵으로 진단된 19명 중 객담도말 및 배양검사와 조직검사로 확인된 경우가 14명, 균음성이나 임상적으로 의심되는 경우가 5명이었다. 간질환 및 관련된 합병증으로 입원한 환자 28명 중 B형 및 C형 간염바이러스에 관련된 경우는 5명(17.9%)에불과하였고 결핵은 19명중 13명(68.4%)이 폐결핵 및 림프절종대의 증상으로 입원치료를 받았다. 복합 감염의 경우는 총 9명이었는데 후천면역결핍증후군 환자였던 2명중 1명이 결핵에 이환되어 있으면서 VDRL 양성소견을 보였고 다른 1명이 HIV와 결핵의 동시감염이었다. 결론 : 노숙자 입원환자에서 결핵, C형 간염 및 매독의 유병율이 일반 인구에 비해 높았다. 노숙자환자를 담당하는 의료인력를 보호하고 환자의 감염질환 유무를 파악하기 위해 적절한 선별검사가 필요하며 감염질환의 확산을 방지하기 위한 정부의 적극적인 대책이 필요하다. Background : Despite the expected high prevalence of several infectious diseases among the homeless, a majority of them have not received screening test and early treatment. Materials and Methods : The subjects of this study were 269 homeless patients who had been hospitalized in the National Medical Center (Korea) between January 2002 and August 2004. Their medical histories and records were reviewed to analyze the prevalence and clinical characteristics of hepatitis B and C, syphilis, tuberculosis and HIV infection among them. Results : The entire 269 homeless patients being hospitalized during the period of this study consist of 249 male patients and 19 female patients. For the prevalence of infectious diseases, HBV was seen in 15 of 228 patients (6.6%); HCV in 8 of 113 patients (7.1%); VDRL positive in 25 of 234 patients (10.7 %); HIV antibody positive in 2 of 130 (1.5%); and tuberculosis in 19 of 269 (7.1%). The number of patients who had the antibody to hepatitis B was 118 (51.7%). Of 28 patients hospitalized with the chief complaints of liver diseases and/or their complications, the number of cases infected with hepatitis B and C viruses was only 5 (17.9%). On the other hand, for patients with tuberculosis, 13 of 19 cases (68.4%) were hospitalized with the chief complaints associated with symptoms of pulmonary tuberculosis or enlarged lymph nodes. The number of patients with multiple infectious diseases was 9 in total. Conclusion : As expected, the prevalence of some infectious diseases were higher among the homeless inpatients, than non-homeless population. Proper screening tests in order to determine the presence of any infectious diseases among the patients and protect involved medical staff are necessary. Further, the government should take proactive measures to prevent the spread of infectious diseases in the aspect of public health.

임부의 연령에 따른 보완대체요법에 관한 인식 태도 경험 비교 연구

김연진,김지연,노경민,신혜리,유예지,이지민,장희조,정아인,최소정,강숙정,이향연,민혜영 이화여자대학교 간호과학대학 2016 이화간호학회지 Vol.- No.50

Purpose: This study aims to test if the age of pregnant women affects the perception, experience, and attitude towards complementary alternative therapy (CAT), by investigating the perception, experience, and attitude of pregnant women under the age of 35, and above 35 (Advanced Maternal Age). The study will 1) find the general characteristics of pregnant women under and over the age of 35 2) compare the perception, behavior, and experience of pregnant women under and over the age of 35, and 3) find the comparison of the perception, behavior, and experience according to the general characteristics of pregnant women under and over the age of 35. Method: The subjects of this study are composed of 44 women under the age of 35 and 44 women above the age of 35, totaling 88 pregnant women visiting midwiferies, obstetrics and gynecology, and baby fairs in Seoul and Gyeong-Gi area. Data for this study was collected from November 28, 2015 to January 6, 2016 for 40 days. The collected data analyzed mean, standard deviation, t test, ANOVA, and chi-square by using SPSS 23.0. Result Results show that there is a significant difference in the perception, attitude, and experience of the two-sample groups in the use of CAT. The question of “what is most necessary when applying CAT in a hospital clinical environment” for the perception criteria came out with the results of t=9.980, p<.05. For the attitude, results showed that the answers of pregnant women under the age of 35 displayed a more positive attitude towards CAT. (t=2.421, p<.05) Lastly, in the experience section, pregnant women under the age of 35 showed more CAT use than the other sample group. Conclusion Results have shown that there is a difference in the perception, behavior, and experience between the two sample groups. Therefore further research on the efficacy and the adverse effects of CAT needs to be done.

The relationship between ovarian volume and related clinical-hormonal parameters in Korean women with polycystic ovary syndrome

( Hye Kyung Noh ),( In Hye Kim ),( Hyun Joo Lee ),( Jong Kil Joo ) 대한산부인과학회 2020 대한산부인과학회 학술대회 Vol.106 No.-

Objective: The aim of this study was to evaluate the relationship between ovarian volume and clinical-hormonal parameters including anti-Mullerian hormone (AMH) in Korean women with polycystic ovary syndrome (PCOS). Methods: A total of 94 Korean women aged 20 to 40 years were included in this study and they were newly diagnosed with PCOS using 2003 revised Rotterdam criteria at Pusan national university hospital. The volumes of each ovary were measured using ultrasonography at the time of diagnosis. The clinical parameters, such as hirsutism, acne, alopecia and oligo-anovulation were investigated. The hormonal parameters including serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), total testosterone, free testosterone, dehydroepiandrosterone sulfate (DHEA-S) and AMH levels were measured in the early follicular phase. The correlation between ovarian volume and clinical-hormonal parameters was investigated using Pearsons correlation coefficients and linear regression analysis. Results: Mean ovarian volume had positive correlation with only serum total testosterone (r = 0.244, p = 0.046), but had no correlation with serum AMH (r = 0.128, p = 0.244), free testosterone (r = 0.098, p = 0.429), hirsutism (r = -0.064, p = 0.542), acne (r = -0.028, p = 0.787), alopecia (r = 0.045, p = 0.665) or irregular menstruation (r = 0.132, p = 0.203). Serum AMH levels had negative correlation with body mass index (r = -0.266, p = 0.014). Conclusion: Mean ovarian volume had weakly positive correlation with serum AMH levels, but it showed no statistical significance. Therefore, we should be more cautious when using AMH levels as surrogate for ultrasonographic appearance in PCOS patients.

Annealing effect on the microstructure and electrochemical properties of Fe2O3/H-TiNT/FTO thin film.

Noh, Kyung-Jong,Oh, Hyo-Jin,Ku, Hye-Kyung,Jung, Sang-Chul,Kang, Wooseung,Park, Sung,Kiml, Sun-Jae American Scientific Publishers 2013 Journal of nanoscience and nanotechnology Vol.13 No.3

<P>A layer of titanate nanotubular (H-TiNT) particles between Fe2O3 film and FTO substrate was inserted and heat-treated to improve electrochemical property of Fe2O3 for water splitting. Heat-treatment of the synthesized F2O3/H-TiNT/FTO thin film was found to significantly affect photoelectrochemical properties of the film through electrochemical impedance analysis. The film showed larger oxidation-reduction peaks of I-V characteristics and capacitive properties under UV-Vis light illumination with heat treatment temperatures during transformation of H-TiNT into anatase TiO2 phase. The overall results showed an appropriate heat treatment was a promising way to improve the electrochemical property of the photoanode film.</P>

Multi-gene panel next generation sequencing is effective for detection of both germline and somatic BRCA mutation in epithelial ovarian cancer

( Hye Kyung Noh ),( Byung Su Kwon ),( Kyung Un Choi ),( Dong Soo Suh ),( Ki Hyung Kim ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-

Objective: We investigated the efficacy of multi-gene panel next generation sequencing (NGS) in formalin-fixed, paraffin-embedded (FFPE) tissue of epithelial ovarian cancer (EOC) patients compared to blood Sanger sequencing. Methods: A total of 48 EOC patients were participated in this study. All of them were conducted both blood Sanger sequencing and tissue NGS, and 17 patients were BRCA mutants. Clinical and pathological data were retrospectively reviewed including age at diagnosis, histology and stage. Sanger sequencing was done using peripheral blood leukocytes and DNA extracted by Promega DNA purification kit. FFPE tissue was used to capture the target regions of 90 cancer-related genes by Illumina MiSeqDx instrument. The clinical significance of detected mutation was evaluated by aggregating several tools such as BIC and ClinVar database. Results: The median age was 56.1 years old, and the most common histology and FIGO stage were serous carcinoma (n=40, 83.3%) and stage III (n=37, 77.1%), respectively. The majority (79.1%) of the 48 patients were non-carrier, but 8 patients (16.7%) had germline mutation and 2 patients (4.2%) had somatic mutation. Blood Sanger sequencing detected 8 pathogenic variants and 10 VUS, which mean germline mutation. Two pathogenic variants and 9 VUS detected in FFPE tissue NGS but not detected in blood Sanger sequencing are somatic mutation. A total of 18 variants were detected in blood Sanger sequencing, including 8 pathogenic variants and 10 variants of uncertain significance (VUS). In contrast, 29 variants were detected in FFPE tissue NGS, including 10 pathogenic variants and 19 VUS. FFPE tissue NGS detected all the mutation detected in blood Sanger sequencing. Moreover, tissue NGS detected 11 additional somatic mutation, including 2 pathogenic variants and 9 VUS. Conclusion: FFPE tissue NGS is effective for detection of both germline and somatic mutation, therefore it has advantages in that it can detect additional somatic mutation compared to blood Sanger sequencing.

Complete hydatidiform mole with massive intrauterine hemorrhage in an adolescent girl

( Hye Kyung Noh ),( Hyun Nyung Jo ),( Sul Lee ),( Byung Su Kwon ),( Dong Soo Suh ),( Ki Hyung Kim ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-

Hydatidiform mole (HM) is a premalignant proliferative trophoblastic disorder. Vaginal bleeding is the most common presenting symptom in women with HM. A 17-year-old nulliparous adolescent girl presented with progressive lower abdominal pain and pronounced nausea and vomiting of about a week’s duration. Her gestational age was 12 weeks and 4 days according to her last menstruation date. Pelvic examination revealed a closed cervical os and no uterine bleeding. Subsequent ultrasound and magnetic resonance imaging (MRI) depicted a T2-hyperintense, huge intrauterine mass, numerous cystic spaces, and massive peri-lesional hemorrhage. Immediately after introducing a forcep into the uterine cavity for suction curettage, a large amount of trophoblastic tissue was expelled and sudden gushes of blood with clots were passed. Histological examination and p57 immunohistochemistry resulted in a final diagnosis of complete hydatidiform mole. Massive intrauterine concealed hemorrhage in an adolescent is a rare complication of complete hydatidiform mole. Key words: Complete hydatidiform mole, massive intrauterine hemorrhage, abdominal pain.