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남자 중학생의 식품 중량과 열량을 중심으로 한 영양교육 효과에 관한 연구
신혜주,김은영,배윤정,승정자 숙명여자대학교 건강·생활과학연구소 2006 生活科學硏究誌 Vol.- No.22
This study was planned to suggest countermeasure of nutrition education by investigating adolescents, dietary behavior, food weight, and acknowledgement of food calories. 210 middle school boys were selected and asked to fill out the questionnaire. The subjects were divided by nutrition education experience; 1st grade who received nutrition session and 3rd grade who divided subjects. In terms of acknowledgement of food calories subjects nutrition education experience had more recognition for calories than the other group(p<0.01). When one bowl of rice, a potato, a bowel of kimchi and a carrot were asked. However recognition for meats, fishes and eggs were not different between two groups. Among milk and dairy foods the educated group showed high recognition both calories and weight of a piece of cheese than the other(p<0.05). The educated group showed better recognition for calories and weight of tea-spoon of butter, a tea spoon of oil and a tea-spoon of mayonaise, compared to the other group(p<0.01, p<0.05, p<0.05). Also the educated group showed better recognition for calories and weight of a packet of shrimp snack than the other group. The results of this study suggest that nutrition education improved the recognition of calories and weights of foods in study subjects. Also, the number of foods recognized for their calories and weights was higher among subjects who received nutrition education. These results will influence the choice the food by adolescents. Also the nutrition education are thought to be more effective by using photographs or food models, not just by lectures on theories.
권경주,정성애,심기남,정정화,강석형,송도경,전승정,김혜인 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.1
Until recently, colorectal polyps were classified predominantly as hyperplastic or adenomatous. While adenomatous polyps are well-characterized precursor lesions of adenocarcinomas, hyperplastic polyps have been considered as benign lesion. However, some hyperplastic polyps with serrated morphology of the crypts have been recognized to have distinctive features and these polyps were termed ‘serrated adenomas’. Recent data show that sessile serrated adenomas (SSA) might be the precursors of serrated colonic cancers, underlining the necessity of identifying them. SSA is approximately 3% of all polyps, commonly appears as flat or sessile and yellowish due to mucus production. In the pathogenesis of SSA, progression to high grade dysplasia or early invasive carcinoma may be associated with serrated neoplasia pathway different from adenoma-carcinoma sequence. We report a case with a colon polyp diagnosed as sessile serrated adenoma with high grade dysplasia after endoscopic submucosal dissection.
In Vivo Bioluminescent Imaging of Rat Mesenchymal Stem Cells in a Mouse Model of Hindlimb Ischemia
( Hye Kyung Chung ),( June Key Chung ),( Joo Hyun Kang ),( Seung Hoo Kim ),( Hyun Joo Kim ),( Dong Soo Lee ) 한국조직공학·재생의학회 2009 조직공학과 재생의학 Vol.6 No.4
We developed a luciferase gene imaging system using a retrovirus for monitoring mesenchymal stem cell distribution. Retrovirus expressing firefly luciferase was infected into rat mesenchymal stem cells(rMSCs). rMSC-luc cells were excellent correlations between in vitro and in vivo bioluminescent activities and cell numbers. After systemic injections of cells in mice, luminescence activity was observed until six days, but was not detected in ischemic regions. After local injection with scaffold, luminescence activities were detected in injection sites over 3 weeks. This system could be a useful means for in vivo real time imaging of stem cell distributions, viability, and trafficking.
노인 도시락 봉사활동을 위한 디자인 제안 -정성적 조사 방법을 중심으로
백혜주 ( Hye Joo Back ),정주현 ( Joo Hyun Chung ) 한국기초조형학회 2013 기초조형학연구 Vol.14 No.1
‘드림’ 도시락 세트 프로젝트는 독거노인 도시락 봉사를 위한 디자인을 제안해보기로 했다. 직접 독거노인 도시락 사회 활동 단체에 참가하여 도시락 봉사의 시스템과 실질적인 문제를 체험하고 분석하여 컨셉 아이디어를 창출하였다. 노인의 심리적 특성을 고려하여 정성적 연구 방법 중 두 가지의 구체적 방식을 시도하였다. 첫째, 비디오 에쓰노그래피를 이용하여 독거노인의 행태를 수집하고 문제점을 분류한다. 둘째, 컬쳐코드 방식을 통하여 독거노인들의 도시락에 대한 문화적 코드를 도출해낸다. 이번 연구를 통한 디자인 제안은 정성적 연구 방법을 통해 컨셉을 내고 구체적인 디자인을 완성했다는데 의의를 둘 수 가 있으며, 노인들의 심리적 특성에 대한 이러한 조사 방법들의 기대 효과를 볼 수 있을 것이다. Lunchbox set ``Drim`` suggest a design for social service for seniors. We experienced actual problem of lunchbox deliver system through attending social service organization. Because of psychological attribute of the senior citizens, we tried two specific qualitative research methods. First, collect the behavior of senior with video ethnography survey method and categories the issues. Second, deduce cultural code about senior`s lunchbox by using ``Culture code`` method. Qualitative research method reach to design concept and it finally finish design of lunchbox; that is important meaning of this study. Two survey methods will show clear effect for senior`s psychological attribute.
정혜주(Hye Joo Chung),박재현(Jae Hyun Park),김재희(Jae Hee Kim),김영옥(Young Ok Kim),정승태(Seung Tae Chung),김진호(Jin Ho K im),조은득(Eun Deuk Cho),조대현(Dae Hyun Cho),노건응(Geun Woong Noh),김동섭(Dong Sup Kim) 대한약학회 2001 약학회지 Vol.45 No.1
The pork meat been reported as one of the food occurring allergic reactions predominantly to korean. To identify the potential food allergens in pork meat, sera were collected from 25 allergic patients to the pork meat and 10 allergic patients not to pork meat as well as 5 normal subjects after skin prick test and open food challenge test. Crude extracts were prepared by blending raw pork meat in phosphate buffered saline (pH 7.0) and the heat treatment on crude extracts was carried to characterize sensibility of the allergens to heat. ELISA was performed to determine specfic IgE antibody levels of allergic patients to pork meat, and resulted in twofold higher mean value than that of tolerated patients. Extracted proteins from pork meat was separated with SDS-PAGE followed by immunoblotting using sera from pork sensitive patients and control subjects, respectively. The IgE binding response to pork meat by immunobots correlated with quentitative specfic IgE value of each person. Immunoblots showed four prominent IgE-binding bands (66, 60, 50, 44kDa) in crude extract, but two bands of those (60, 44kDa) were heat-labile. These results suggest that most prominent allergens from pork meat are four components(66, 60, 50, 44 kDa) in korean and the heat treatment on allergen is additional parameter to characterize allergen.
Kim, Hye Ryun,Shim, Hyo Sup,Chung, Jin‐,Haeng,Lee, Young Joo,Hong, Yun Kyoung,Rha, Sun Young,Kim, Se Hoon,Ha, Sang‐,Jun,Kim, Se Kyu,Chung, Kyung Young,Soo, Ross,Kim, Joo Hang,Cho, Byoung C Wiley Subscription Services, Inc., A Wiley Company 2012 Cancer Vol.118 No.3
<P><B>Abstract</B></P><P><B>BACKGROUND:</B></P><P>The objectives of this study were to determine the proportions of major oncogenic alterations and to examine survival in genotype‐specific subsets of never‐smokers with nonsmall cell lung cancer (NSCLC).</P><P><B>METHODS:</B></P><P>The authors concurrently analyzed mutations in the epidermal growth factor receptor (<I>EGFR</I>) and v‐Ki‐<I>ras</I>2 Kirsten rat sarcoma viral oncogene homolog (<I>KRAS</I>) genes and investigated anaplastic lymphoma kinase (<I>ALK</I>) gene rearrangements in samples from 229 never‐smokers with NSCLC. <I>ALK</I> rearrangements were identified by fluorescent in situ hybridization and were confirmed by immunohistochemistry. Mutations in <I>EGFR</I> (exons 18 to 21) and <I>KRAS</I> (codons 12 and 13) were determined by direct sequencing.</P><P><B>RESULTS:</B></P><P>Of 229 tumors, the frequency of <I>EGFR</I> mutations, <I>ALK</I> rearrangements, <I>KRAS</I> mutations, and no mutations (wild type [WT]) in any of the 3 genes (<I>WT/WT/WT</I>) was 48%, 8.3%, 3.5%, and 40.2%, respectively. All genetic alterations were mutually exclusive. The median progression‐free survival after treatment with EGFR tyrosine kinase inhibitors (TKIs) was 12.8 months, 6.3 months, 2.1 months, and 1.6 months in patients with <I>EGFR</I> mutations, the <I>WT/WT/WT</I> genotype, <I>KRAS</I> mutations, and <I>ALK</I> rearrangements, respectively. In a Cox regression model, the adjusted hazard ratio for the risk of disease progression after treatment with EGFR TKIs was 0.59 (95% confidence interval [CI], 0.40‐0.87; <I>P</I> = .008) for patients with <I>EGFR</I> mutations, 4.58 (95% CI, 2.07‐10.15; <I>P</I> < .001) for patients with <I>ALK</I> rearrangements, and 4.23 (95% CI, 1.65‐10.8; <I>P</I> = .003) for patients with <I>KRAS</I> mutations. Overall survival also differed significantly among genotypes.</P><P><B>CONCLUSIONS:</B></P><P>To the authors' knowledge, this was the largest comprehensive and concurrent analysis to date of 3 major oncogenic alterations in a cohort of East Asian never‐smokers with NSCLC. Because survival outcomes differed among genotypes, and drugs that target specific alterations currently are available, genetic profiling to identify genotype‐specific subsets can lead to successful treatment with appropriate kinase inhibitors. Cancer 2012;. © 2011 American Cancer Society.</P>