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Hundo Cho,Jin-Hyuk Choi,Seok Yun Kang,Hyun Woo Lee,Yong Won Choi,Tae-Hwan Kim,Mi Sun Ahn,Chul-Ho Kim,Yoo Seob Shin,Jeon Yeob Jang,Young-Taek Oh,Jaesung Heo,Seung Soo Sheen 대한내과학회 2022 The Korean Journal of Internal Medicine Vol.37 No.3
Background/Aims: The study investigated the incidence of thromboembolic events (TEE) in head and neck (H&N) cancer patients who received concurrent chemoradiotherapy (CCRT) with cisplatin, and analyzed the factors affecting TEE occurrence Methods: Two hundred and fifty-seven patients who started CCRT with cisplatin for H&N cancer from January 2005 to December 2019 were analyzed. Results: TEE occurred in five patients, an incidence rate of 1.9%. The 2-, 4-, and 6-month cumulative incidences of TEE were 0.8%, 1.6%, and 1.9%, respectively. Khorana score was the only factor associated with TEE occurrence (p = 0.010). Conclusions: The incidence of TEE in H&N cancer patients who underwent CCRT with cisplatin was relatively low when compared to other types of cancer. However, patients with a high Khorana score require more careful surveillance for possible TEE occurrence.
( Young-sil An ),( Chang-hee Suh ),( Ju-yang Jung ),( Hundo Cho ),( Hyoun-ah Kim ) 대한내과학회 2017 The Korean Journal of Internal Medicine Vol.32 No.6
Background/Aims: <sup>18</sup>F-fluorodeoxyglucose positron emission tomography/computed tomography (<sup>18</sup>F-FDG PET/CT) has been suggested as a reliable imaging technique for monitoring of disease activity in patients with adult-onset Still’s disease (AOSD). Therefore, we investigated the clinical significance of <sup>18</sup>F-FDG PET/CT in Korean AOSD patients. Methods: Thirteen AOSD patients were included in the study. The PET/CT images were evaluated with visual and semiquantitative method using standardized uptake values (SUVs). Results: The presence of increased <sup>18</sup>F-FDG uptake was noted in 90% of clinically active AOSD patients. <sup>18</sup>F-FDG uptake was located in the lymph node, spleen, and bone marrow. Visual grade and SUV intensity of lymph node was significantly correlated with the systemic score of AOSD. Visual grade of spleen was significantly correlated with the systemic score, erythrocyte sedimentation rate (ESR), and ferritin. Additionally, visual grade and SUV intensity of bone marrow was significantly correlated with the systemic score, ESR, leukocyte, and neutrophil. Conclusions: Visual grade and SUV intensity of lymph node, spleen, and bone marrow on <sup>18</sup>F-FDG PET/CT scan showed significant correlations with known disease activity markers. The data suggest that <sup>18</sup>F-FDG PET/CT scan may be a useful imaging technique for evaluation of disease activity in AOSD patients.
내시경적 절제술로 완전 절제된 바터 팽대부의 신경절세포 부신경절종 1예
정진희 ( Jin-hee Jung ),유병무 ( Byung Moo Yoo ),엄유진 ( Yoo Jin Um ),조헌도 ( Hundo Cho ),안영환 ( Young Hwan Ahn ),양민재 ( Min Jae Yang ),황재철 ( Jae Chul Hwang ),김진홍 ( Jin Hong Kim ) 대한췌담도학회 2016 대한췌담도학회지 Vol.21 No.2
저자들은 십이지장의 팽대부에서 발견된 종양에 대해 조직검사를 시행, 신경내분비종으로 판단하여 내시경적 유두부 절제술을 시행하였으며 신경절세포 부신경절종으로 진단된 증례를 경험하였으며, 신경절세포 부신경절종이 내시경적 유두부절제술로 성공적으로 치료되었기에 문헌고찰과 더불어 보고하는 바이다. Gangliocytic paraganglioma (GP) is an extremely rare tumor that mostly occurs in the periampullary area of the duodenum. It is characterized by benign behavior and favorable outcomes, but sometimes shows regional lymph node dissemination. GP consist of three characteristic histological components: epithelioid, spindle, and ganglion cells. Therefore, it is often misdiagnosed as a neuroendocrine tumor when only endoscopic forceps biopsy is performed. The clinical management of GP has not yet been standardized. This case report describes an asymptomatic patient who was initially diagnosed with a grade-1 neuroendocrine tumor, but was confirmed as having benign GP after endoscopic papillectomy. Complete en-bloc resection was performed for this patient, without any significant adverse events. At a 6-month follow-up assessment, the patient remained asymptomatic and there was no evidence of recurrence.
만성담낭염으로 발현되고 류마티스성 다발성 근육통으로 오진된 아밀로이드증 1예
엄유진 ( Yoo Jin Um ),김현아 ( Hyoun Ah Kim ),정진희 ( Jin Hee Jung ),조헌도 ( Hundo Cho ),강준구 ( Joon Koo Kang ) 대한소화기학회 2016 대한소화기학회지 Vol.68 No.1
Amyloidosis is a rare disease defined by extracellular deposits of amorphous fibrillar proteins, derived from aggregations of misfolded proteins. Localization of amyloidosis in the gallbladder is uncommon; only eight cases have been reported. We describe a case of amyloidosis diagnosed by cholecystectomy, which possibly also affected the liver and kidney. The patient was misdiagnosed with polymyalgia rheumatica, but after a cholecystectomy to treat chronic cholecystitis, we ultimately diagnosed him with amyloidosis. We review amyloidosis with gallbladder involvement in the literature. (Korean J Gastroenterol 2016;68:49-53)